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cisapride and Pheochromocytoma

cisapride has been researched along with Pheochromocytoma in 1 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"The gastroprokinetic agent metoclopramide is known to stimulate catecholamine secretion from pheochromocytomas."7.75Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors. ( Anouar, Y; Bastard, C; Bertherat, J; Cartier, D; Compagnon, P; Guillemot, J; Kuhn, JM; Lefebvre, H; Lihrmann, I; Pichon, P; Plouin, PF; Thouennon, E; Thuillez, C; Yon, L, 2009)
"The gastroprokinetic agent metoclopramide is known to stimulate catecholamine secretion from pheochromocytomas."3.75Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors. ( Anouar, Y; Bastard, C; Bertherat, J; Cartier, D; Compagnon, P; Guillemot, J; Kuhn, JM; Lefebvre, H; Lihrmann, I; Pichon, P; Plouin, PF; Thouennon, E; Thuillez, C; Yon, L, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guillemot, J1
Compagnon, P1
Cartier, D1
Thouennon, E1
Bastard, C1
Lihrmann, I1
Pichon, P1
Thuillez, C1
Plouin, PF1
Bertherat, J1
Anouar, Y1
Kuhn, JM1
Yon, L1
Lefebvre, H1

Other Studies

1 other study available for cisapride and Pheochromocytoma

ArticleYear
Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors.
    Endocrine-related cancer, 2009, Volume: 16, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Catecholamines; Chromogranins; Cisapride; Contraindication

2009