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cisapride and Nausea

cisapride has been researched along with Nausea in 10 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"To assess the efficacy of cisapride therapy in relieving symptoms of functional dyspepsia."9.08Efficacy of cisapride therapy in functional dyspepsia. ( Cowan, H; Eckstein, RP; Höschl, R; Kellow, JE; Lam, SK; Lunzer, MR; Riley, JW; Shuter, B, 1995)
"Cisapride and ranitidine improved the symptoms of diffuse epigastric pain, postprandial epigastric fullness, epigastric distension, belching, heartburn, regurgitation, and nausea when compared with baseline."9.08Cisapride compared with ranitidine in the treatment of functional dyspepsia. ( Carvalhinhos, A; Fidalgo, P; Freire, A; Matos, L, 1995)
"Low doses of cisapride (5-10 mg twice daily) produced relatively rapid relief from nausea elicited by venlafaxine in six patients with treatment-refractory recurrent major depression."9.08Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression. ( Russell, JL, 1996)
"To highlight a case of torsade de pointes ventricular arrhythmia induced by the concomitant use of cisapride and clarithromycin."7.70Torsade de pointes induced by cisapride/clarithromycin interaction. ( Piquette, RK, 1999)
"To assess the efficacy of cisapride therapy in relieving symptoms of functional dyspepsia."5.08Efficacy of cisapride therapy in functional dyspepsia. ( Cowan, H; Eckstein, RP; Höschl, R; Kellow, JE; Lam, SK; Lunzer, MR; Riley, JW; Shuter, B, 1995)
"Cisapride and ranitidine improved the symptoms of diffuse epigastric pain, postprandial epigastric fullness, epigastric distension, belching, heartburn, regurgitation, and nausea when compared with baseline."5.08Cisapride compared with ranitidine in the treatment of functional dyspepsia. ( Carvalhinhos, A; Fidalgo, P; Freire, A; Matos, L, 1995)
"Low doses of cisapride (5-10 mg twice daily) produced relatively rapid relief from nausea elicited by venlafaxine in six patients with treatment-refractory recurrent major depression."5.08Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression. ( Russell, JL, 1996)
"To highlight a case of torsade de pointes ventricular arrhythmia induced by the concomitant use of cisapride and clarithromycin."3.70Torsade de pointes induced by cisapride/clarithromycin interaction. ( Piquette, RK, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's8 (80.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kellow, JE1
Cowan, H1
Shuter, B1
Riley, JW1
Lunzer, MR1
Eckstein, RP1
Höschl, R1
Lam, SK1
Carvalhinhos, A1
Fidalgo, P1
Freire, A1
Matos, L1
Bergeron, R1
Blier, P1
Güller, R1
Reichlin, B1
Jost, G1
Russell, JL1
Bohn, P1
Sternbach, H1
Amchin, J1
Albano, D1
Piquette, RK1
Stacher, G1
Gaupmann, G1
Mittelbach, G1
Schneider, C1
Steinringer, H1
Langer, B1

Trials

5 trials available for cisapride and Nausea

ArticleYear
Efficacy of cisapride therapy in functional dyspepsia.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Dyspepsia; Eructation; Female; Gastric Emp

1995
Cisapride compared with ranitidine in the treatment of functional dyspepsia.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:5

    Topics: Adult; Antacids; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Dyspepsia; Eructation; Female; F

1995
[Colonic preparation with sodium phosphate. Prospective, randomized, placebo-controlled double blind study with various antiemetics].
    Schweizerische medizinische Wochenschrift, 1996, Aug-06, Volume: 126, Issue:31-32

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Cathartics; Cisapride

1996
Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Cisapride; Cyclohexanols; Depressive Disorder; Drug

1996
Effects of oral cisapride on interdigestive jejunal motor activity, psychomotor function, and side-effect profile in healthy man.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:11

    Topics: Administration, Oral; Adult; Blood Pressure; Cisapride; Clinical Trials as Topic; Double-Blind Metho

1987

Other Studies

5 other studies available for cisapride and Nausea

ArticleYear
[With evidence-based phytotherapy. Takes away gastric and intestinal irritation].
    MMW Fortschritte der Medizin, 2003, Mar-27, Volume: 145, Issue:13

    Topics: Antiemetics; Cisapride; Clinical Trials as Topic; Dopamine Antagonists; Evidence-Based Medicine; Gas

2003
Cisapride for the treatment of nausea produced by selective serotonin reuptake inhibitors.
    The American journal of psychiatry, 1994, Volume: 151, Issue:7

    Topics: Adult; Cisapride; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Nausea; Pipe

1994
Social phobia-related nausea relieved with adjunctive cisapride.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: 1-Naphthylamine; Adolescent; Cisapride; Drug Therapy, Combination; Humans; Male; Nausea; Phobic Diso

1997
Clinical considerations in managing nausea associated with venlafaxine.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Cisapride; Cyclohexanols; Depressive Disorder; Gastrointes

1997
Torsade de pointes induced by cisapride/clarithromycin interaction.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Cisapride; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enz

1999