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cisapride and Muscle Contraction

cisapride has been researched along with Muscle Contraction in 51 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to compare the effect of EM574 with that of cisapride on gastric motility and emptying in normal and gastroparesis dogs."7.70Effects of EM574 and cisapride on gastric contractile and emptying activity in normal and drug-induced gastroparesis in dogs. ( Itoh, Z; Mizumoto, A; Mochiki, E; Omura, S; Suzuki, H; Tanaka, T, 1998)
"To determine whether ether-a-go-go (ERG) potassium channels are expressed in equine gastrointestinal smooth muscle, whether ERG channel antagonists affect jejunal muscle contraction in vitro, and whether plasma cisapride concentrations in horses administered treatment for postoperative ileus (POI) are consistent with ERG channels as drug targets."3.72Expression of the ether-a-go-go (ERG) potassium channel in smooth muscle of the equine gastrointestinal tract and influence on activity of jejunal smooth muscle. ( Finley, MR; Freeman, LC; Ganta, S; Lillich, JD; Rakestraw, PC; Roussel, AJ, 2003)
" The aim of this study was to compare the effect of EM574 with that of cisapride on gastric motility and emptying in normal and gastroparesis dogs."3.70Effects of EM574 and cisapride on gastric contractile and emptying activity in normal and drug-induced gastroparesis in dogs. ( Itoh, Z; Mizumoto, A; Mochiki, E; Omura, S; Suzuki, H; Tanaka, T, 1998)
"The cisapride induced increase in oesophageal contractile force and propagation velocity seems to enhance the clearance of gastro-oesophageal reflux."2.67Effects of ranitidine and cisapride on acid reflux and oesophageal motility in patients with reflux oesophagitis: a 24 hour ambulatory combined pH and manometry study. ( Armstrong, D; Bettschen, HU; Blum, AL; Emde, C; Halter, F; Huber, T; Inauen, W; Merki, HS; Scheurer, U; Weber, B, 1993)
"Cisapride is a newly developed substance that stimulates gastrointestinal motility, possibly enhancing acetylcholine release in the gut wall."2.66Effects of cisapride, a new gastrointestinal prokinetic substance, on interdigestive and postprandial motor activity of the distal oesophagus in man. ( Akkermans, LM; Bogaard, JW; Grade, AC; Smout, AJ; ten Thije, OJ; Wittebol, P, 1985)
" On a molar basis, TD-5108 was approximately twofold less potent than tegaserod following intravenous dosing but 6- or 86-fold more potent than cisapride or mosapride, respectively, and 9- or 18-fold more potent than tegaserod or cisapride, respectively, after intraduodenal administration."1.35The in vivo gastrointestinal activity of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity. ( Armstrong, SR; Beattie, DT; Humphrey, PP; Marquess, D; Sandlund, C; Shaw, JP; Smith, JA; Taylor, JA, 2008)
"Cisapride was less potent than 5-HT and acted as a partial agonist relative to 5-HT."1.32Serotonin-induced potentiation of cholinergic responses to electrical field stimulation in normal and neurogenic overactive human detrusor muscle. ( Chapple, CR; Chess-Williams, R; Martin, SW; Radley, SC; Sellers, DJ, 2004)
"Cisapride has almost the same characteristics, but the present findings suggest the involvement of motilin and 5-HT3 receptors in the effects of cisapride."1.30Effect of TKS159, a novel 5-hydroxytryptamine4 agonist, on gastric contractile activity in conscious dogs. ( Haga, N; Itoh, Z; Mizumoto, A; Mochiki, E; Shiba, Y; Suzuki, H, 1998)
"Cisapride has been shown in a number of recent studies to have prokinetic effects on the gastrointestinal tract."1.28Cisapride inhibits motility of the sphincter of Oddi in the Australian possum. ( Baker, RA; Saccone, GT; Toouli, J, 1990)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199011 (21.57)18.7374
1990's27 (52.94)18.2507
2000's10 (19.61)29.6817
2010's3 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schaus, JM1
Thompson, DC1
Bloomquist, WE1
Susemichel, AD1
Calligaro, DO1
Cohen, ML1
Becker, DP1
Flynn, DL1
Moormann, AE1
Nosal, R1
Villamil, CI1
Loeffler, R1
Gullikson, GW1
Moummi, C1
Yang, DC1
Kullmann, FA1
Kurihara, R1
Ye, L1
Wells, GI1
McKenna, DG1
Burgard, EC1
Thor, KB1
Jin, YR1
Jin, J1
Piao, XX1
Jin, NG1
Chai, W1
Chan, KY1
de Vries, R1
van den Bogeardt, AJ1
de Maeyer, JH1
Schuurkes, JA6
Villalón, CM1
Saxena, PR1
Danser, AH1
MaassenVanDenBrink, A1
Yau, KI2
Hwang, TL1
Lillich, JD1
Rakestraw, PC1
Roussel, AJ1
Finley, MR1
Ganta, S1
Freeman, LC1
Shimatani, H1
Kojima, Y1
Kadowaki, M1
Nakagawa, T1
Fujii, H1
Nakajima, Y1
Takaki, M3
Chapple, CR1
Radley, SC1
Martin, SW1
Sellers, DJ1
Chess-Williams, R1
Beattie, DT1
Armstrong, SR1
Shaw, JP1
Marquess, D1
Sandlund, C1
Smith, JA1
Taylor, JA1
Humphrey, PP1
Neya, T2
Itano, N2
Mizutani, M1
Yamasato, T2
Nakayama, S3
Kadlec, O1
Schuurkes, J1
Seferna, I1
Katschinski, M1
Wank, U1
Ducree, M1
Schirra, J1
Arnold, R1
de Ridder, WJ1
Inauen, W1
Emde, C1
Weber, B1
Armstrong, D1
Bettschen, HU1
Huber, T1
Scheurer, U1
Blum, AL1
Halter, F1
Merki, HS1
Briejer, MR1
Akkermans, LM2
Meulemans, AL2
Lefebvre, RA1
Ohno, N1
Zhang, G1
Xue, L1
Yamamoto, Y1
Itoh, M1
Suzuki, H3
Candura, SM2
Messori, E1
Franceschetti, GP1
D'Agostino, G1
Vicini, D1
Tagliani, M1
Tonini, M2
Staiano, A1
Clouse, RE1
Langer, JC1
Bramlett, G1
Wechsung, E1
Houvenaghel, A1
Xynos, E1
Tsiaoussis, J1
Epanomeritakis, E1
Glynos, M1
Haroulakis, N1
Vassilakis, JS1
Gourtsoyiannis, N1
Suzuki, T4
Imanishi, N1
Itahana, H1
Watanuki, S1
Miyata, K2
Ohta, M1
Nakahara, H1
Yamagiwa, Y1
Mase, T1
Haga, N1
Shiba, Y1
Mochiki, E2
Mizumoto, A2
Itoh, Z3
Wetscher, GJ1
Glaser, K1
Wieschemeyer, T1
Gadenstätter, M1
Klingler, P1
Klingler, A1
Hinder, RA1
Tanaka, T1
Omura, S1
Toyota, K1
Takeda, M1
Tsukamoto, K1
Mizutani, Y1
Taniyama, K2
Nagakura, Y1
Akuzawa, S1
Kamato, T1
Ito, H1
Yamaguchi, T1
Ko, FN1
Chien, CH1
Cowles, VE1
Nellans, HN1
Seifert, TR1
Besecke, LM1
Segreti, JA1
Mohning, KM1
Faghih, R1
Verlinden, MH1
Wegner, CD1
Steele, AC1
Walsh, P1
Bentley, M1
Neff, J1
Karram, M1
Nieto, JE1
Van Hoogmoed, LM1
Spier, SJ1
Vatistas, NJ1
Snyder, JR1
Timmerman, BL1
Koutsoviti-Papadopoulou, M1
Nikolaidis, E1
Batzias, GC1
Kounenis, G1
Onori, L1
Coccini, T1
Manzo, L1
Rizzi, CA1
Hasler, WL1
Heldsinger, A1
Owyang, C1
Takeda, K1
Matsuyama, S1
Shirakawa, J1
Sano, I1
Tanaka, C1
Stacher, G3
Bergmann, H2
Gaupmann, G3
Schneider, C3
Kugi, A1
Höbart, J2
Binder, A1
Mittelbach-Steiner, G1
Baker, RA1
Saccone, GT1
Toouli, J1
Van den Brink, HW1
Van Nueten, JM2
Van Rossum, JM1
Steinringer, H1
Stacher-Janotta, G1
Steiner-Mittelbach, G1
Abatzi, TA1
Vogelberg, KH1
Dalügge, A1
Wulschke, S1
Ehrlein, HJ1
Tsiamitas, C1
Wiesnagrotzki, S1
Kiss, A1
Mittelbach, G1
Den Hertog, A1
Van den Akker, J1
Smout, AJ1
Bogaard, JW1
Grade, AC1
ten Thije, OJ1
Wittebol, P1
Van Daele, PG1
Reyntjens, AJ1
Janssen, PA1
Burleigh, DE1
Trout, SJ1
Nakaya, M1
Nakamura, T1

Trials

10 trials available for cisapride and Muscle Contraction

ArticleYear
Cisapride stimulates human esophageal motility.
    Digestion, 1995, Volume: 56, Issue:2

    Topics: Administration, Oral; Adult; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Esophagogastric Junc

1995
Effects of ranitidine and cisapride on acid reflux and oesophageal motility in patients with reflux oesophagitis: a 24 hour ambulatory combined pH and manometry study.
    Gut, 1993, Volume: 34, Issue:8

    Topics: Adult; Aged; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Drug Therapy, Combination; Esophagea

1993
The effects of cisapride on the topography of oesophageal peristalsis.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:6

    Topics: Adult; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Esophagus; Female; Humans; Male; Muscle Co

1996
Effect of oral cisapride on gallbladder emptying during fasting and postprandial states.
    Academic radiology, 1998, Volume: 5, Issue:2

    Topics: Administration, Oral; Adult; Animals; Cisapride; Eating; Fasting; Gallbladder; Gallbladder Emptying;

1998
Cisapride enhances the effect of partial posterior fundoplication on esophageal peristalsis in GERD patients with poor esophageal contractility.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9

    Topics: Adult; Aged; Cisapride; Esophagus; Female; Fundoplication; Gastroesophageal Reflux; Gastrointestinal

1998
A randomized, double-blind placebo-controlled trial of the effects of the 5-hydroxytriptamine(4) agonist cisapride on the female urinary bladder.
    American journal of obstetrics and gynecology, 2001, Volume: 185, Issue:1

    Topics: Adult; Aging; Cisapride; Double-Blind Method; Female; Humans; Linear Models; Middle Aged; Muscle Con

2001
Fat preload delays gastric emptying: reversal by cisapride.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:6

    Topics: Adult; Cisapride; Dietary Fats; Gastric Emptying; Gastrointestinal Motility; Humans; Male; Muscle Co

1990
Effects of cisapride on postcibal jejunal motor activity.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:9

    Topics: Adult; Cisapride; Double-Blind Method; Eating; Fasting; Gastrointestinal Motility; Humans; Jejunum;

1989
Intravenous cisapride accelerates delayed gastric emptying and increases antral contraction amplitude in patients with primary anorexia nervosa.
    Gastroenterology, 1987, Volume: 92, Issue:4

    Topics: Adolescent; Adult; Anorexia Nervosa; Cisapride; Drug Evaluation; Female; Gastric Emptying; Humans; I

1987
Effects of cisapride, a new gastrointestinal prokinetic substance, on interdigestive and postprandial motor activity of the distal oesophagus in man.
    Gut, 1985, Volume: 26, Issue:3

    Topics: Adult; Cisapride; Clinical Trials as Topic; Digestion; Double-Blind Method; Eating; Esophagogastric

1985

Other Studies

41 other studies available for cisapride and Muscle Contraction

ArticleYear
Synthesis and structure-activity relationships of potent and orally active 5-HT4 receptor antagonists: indazole and benzimidazolone derivatives.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Adamantane; Administration, Oral; Adrenergic alpha-Antagonists; Animals; Aorta; Brain; Drug Evaluati

1998
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
    Journal of medicinal chemistry, 2006, Feb-09, Volume: 49, Issue:3

    Topics: Amides; Animals; Benzamides; Bradycardia; Brain; Dogs; Esophagus; Esters; Female; Gastric Emptying;

2006
Effects of the 5-HT4 receptor agonist, cisapride, on neuronally evoked responses in human bladder, urethra, and ileum.
    Autonomic neuroscience : basic & clinical, 2013, Volume: 176, Issue:1-2

    Topics: Adult; Aged; Cisapride; Electric Stimulation; Evoked Potentials; Female; Humans; Ileum; Male; Middle

2013
The effect of Taraxacum officinale on gastric emptying and smooth muscle motility in Rodents.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:8

    Topics: 1-Butanol; Adrenergic alpha-Antagonists; Animals; Atropine; Cisapride; Dose-Response Relationship, D

2011
Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae.
    Life sciences, 2012, Apr-09, Volume: 90, Issue:13-14

    Topics: 5-Methoxytryptamine; Adolescent; Adult; Aged; Benzofurans; Calcium Channels; Child; Cisapride; Femal

2012
The nonadrenergic noncholinergic system can modulate the effect of prokinetic agents on contractile response of isolated guinea-pig trachea segments to electrical field stimulation.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2002, Volume: 101, Issue:10

    Topics: Animals; Autonomic Nervous System; Chymotrypsin; Cisapride; Dopamine Antagonists; Electric Stimulati

2002
Expression of the ether-a-go-go (ERG) potassium channel in smooth muscle of the equine gastrointestinal tract and influence on activity of jejunal smooth muscle.
    American journal of veterinary research, 2003, Volume: 64, Issue:3

    Topics: Animals; Blotting, Western; Cisapride; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Eth

2003
A 5-HT4 agonist mosapride enhances rectorectal and rectoanal reflexes in guinea pigs.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:2

    Topics: Anal Canal; Animals; Benzamides; Cisapride; Guinea Pigs; Indoles; Injections, Intravenous; Male; Mor

2003
Serotonin-induced potentiation of cholinergic responses to electrical field stimulation in normal and neurogenic overactive human detrusor muscle.
    BJU international, 2004, Volume: 93, Issue:4

    Topics: Adult; Cisapride; Electric Stimulation; Humans; Middle Aged; Muscle Contraction; Muscle, Smooth; Pip

2004
The in vivo gastrointestinal activity of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:1

    Topics: Administration, Oral; Animals; Azabicyclo Compounds; Benzamides; Cisapride; Colon; Dogs; Dose-Respon

2008
The effect of cisapride on neural 5-HT receptors in guinea-pig isolated ileum.
    European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1

    Topics: Animals; Cisapride; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscl

1984
The topographical basis and frequency-dependence in the effect of different compounds on neurogenic contractions of the guinea-pig ileum.
    General physiology and biophysics, 1993, Volume: 12, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Cisapride and 5-hydroxytryptamine enhance motility in the canine antrum via separate pathways, not involving 5-hydroxytryptamine1,2,3,4 receptors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: Animals; Atropine; Benzimidazoles; Cisapride; Dogs; Electric Stimulation; Gastrointestinal Motility;

1993
Cisapride and a structural analogue, R 76,186, are 5-hydroxytryptamine4 (5-HT4) receptor agonists on the guinea-pig colon ascendens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:5

    Topics: 4-Aminobenzoic Acid; Animals; Cisapride; Colon; Female; Guinea Pigs; Male; Muscle Contraction; Muscl

1993
Excitation and inhibition by cisapride of spontaneous and evoked electrical responses in smooth muscles of guinea-pig stomach.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 112, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Cisapride; Electric Stimulation; Female; Guinea Pigs; In Vitro Tec

1995
Neural 5-HT4 receptors in the human isolated detrusor muscle: effects of indole, benzimidazolone and substituted benzamide agonists and antagonists.
    British journal of pharmacology, 1996, Volume: 118, Issue:8

    Topics: Benzimidazoles; Cisapride; Dose-Response Relationship, Drug; Humans; Indoles; Muscle Contraction; Pi

1996
Effect of prokinetic agents on ileal contractility in a rabbit model of gastroschisis.
    Journal of pediatric surgery, 1997, Volume: 32, Issue:4

    Topics: Abdominal Muscles; Animals; Animals, Newborn; Bethanechol; Cisapride; Congenital Abnormalities; Eryt

1997
Effect of cisapride on myoelectrical activity of the antrum pylori in the conscious miniature pig.
    Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:4

    Topics: Animals; Area Under Curve; Blood Pressure; Cisapride; Electromyography; Female; Gastric Emptying; In

1997
Novel 5-hydroxytryptamine 4 (5-HT4) receptor agonists. Synthesis and gastroprokinetic activity of 4-amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro-2-methoxybenzamide s.
    Chemical & pharmaceutical bulletin, 1998, Volume: 46, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Benzamides; Cisapride; Crystallography, X-Ray; Dogs; Gastric Emptying; G

1998
Effect of TKS159, a novel 5-hydroxytryptamine4 agonist, on gastric contractile activity in conscious dogs.
    Neurogastroenterology and motility, 1998, Volume: 10, Issue:4

    Topics: Animals; Cisapride; Dogs; Drug Evaluation, Preclinical; Gastrointestinal Agents; Gastrointestinal Mo

1998
Effects of EM574 and cisapride on gastric contractile and emptying activity in normal and drug-induced gastroparesis in dogs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Cisapride; Clonidine; Dogs; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Gastro

1998
Pyloric opening and closure evaluated by means of strain gauge force transducers.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1998, Volume: 34, Issue:1

    Topics: Animals; Cisapride; Dogs; Duodenum; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal

1998
Identification of SK-951, a novel benzofuran derivative, as an agonist to 5-HT4 receptors.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:2

    Topics: Acetylcholine; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cisapride;

1999
Pharmacological properties of a novel gastrointestinal prokinetic benzamide selective for human 5-HT4 receptor versus human 5-HT3 receptor.
    Pharmacological research, 1999, Volume: 39, Issue:5

    Topics: Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Digestive System; Esophagus

1999
Effects of prokinetic agents on contractile responses to electrical field stimulation of isolated guinea pig trachea.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:8

    Topics: Animals; Cisapride; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Metoclopramide; Mu

1999
Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: Animals; Cisapride; Dogs; Dose-Response Relationship, Drug; Erythromycin; Gastric Emptying; Gastroin

2000
Use of an extracorporeal circuit to evaluate effects of intraluminal distention and decompression on the equine jejunum.
    American journal of veterinary research, 2002, Volume: 63, Issue:2

    Topics: Albumins; Animals; Cisapride; Erythromycin; Extracorporeal Circulation; Horses; Intestinal Mucosa; J

2002
Cisapride reverses the anticholinergic effect of disopyramide on the isolated guinea-pig urinary bladder.
    Journal of veterinary pharmacology and therapeutics, 2002, Volume: 25, Issue:2

    Topics: Acetylcholine; Animals; Cholinergic Antagonists; Cisapride; Disopyramide; Dose-Response Relationship

2002
5-hydroxytryptamine4 receptor agonists facilitate cholinergic transmission in the circular muscle of guinea pig ileum: antagonism by tropisetron and DAU 6285.
    Life sciences, 1992, Volume: 50, Issue:21

    Topics: Animals; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapri

1992
Is the action of cisapride on the guinea-pig ileum mediated via 5-HT4 receptors?
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Cisapride; Dose-Response Relationship, Drug; Drug Interactions; Female

1992
Cisapride acts on muscarinic (glandular M2) receptors to induce contraction of isolated gastric myocytes: mediation via a calcium-phosphoinositide pathway.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Cisapride; Gastric Mucosa; Guinea Pigs; Male;

1991
Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: Acetylcholine; Animals; Cisapride; Electric Stimulation; Female; Gastrointestinal Motility; Guinea P

1991
Cisapride inhibits motility of the sphincter of Oddi in the Australian possum.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:6

    Topics: Ampulla of Vater; Animals; Cisapride; Female; Male; Movement; Muscle Contraction; Opossums; Piperidi

1990
R 50 595, a selective non-competitive antagonist of cisapride, BRL 24924 and 5-hydroxytryptamine on the guinea-pig ileum.
    European journal of pharmacology, 1990, May-31, Volume: 181, Issue:1-2

    Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Rin

1990
[Sonographic studies during drug treatment of diabetic gastroparesis].
    Deutsche medizinische Wochenschrift (1946), 1988, Jun-16, Volume: 113, Issue:24

    Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastric Emptying; Gastro

1988
The control mechanisms of gastric emptying are not overridden by motor stimulants.
    The American journal of physiology, 1986, Volume: 251, Issue:6 Pt 1

    Topics: 5-Hydroxytryptophan; Animals; Cisapride; Dogs; Duodenum; Gastric Emptying; Gastrointestinal Motility

1986
The effect of cisapride on smooth muscle cells of guinea-pig taenia caeci.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: Animals; Cecum; Cisapride; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Mus

1986
Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Cisapride; Dose-Response Relationship, Drug; Electric Stimulation;

1985
[Effects of cisapride on the motility of the digestive tract in dogs and guinea pigs].
    Nihon Heikatsukin Gakkai zasshi, 1985, Volume: 21, Issue:1

    Topics: Animals; Atropine; Biliary Tract; Blood Pressure; Cisapride; Dogs; Dose-Response Relationship, Drug;

1985
Evidence against an acetylcholine releasing action of cisapride in the human colon.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Acetylcholine; Cisapride; Colon; Electric Stimulation; Humans; In Vitro Techniques; Muscle Contracti

1985
[Effect of cisapride on contractile activity of the gastrointestinal tract].
    Nihon Heikatsukin Gakkai zasshi, 1985, Volume: 21, Issue:2

    Topics: Animals; Atropine; Cisapride; Dogs; Gastrointestinal Motility; Motilin; Muscle Contraction; Muscle,

1985