cisapride has been researched along with Kidney Failure, Chronic in 11 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One patient died from ventricular arrhythmia 12 days after discontinuing cisapride." | 1.31 | Retrospective analysis of cisapride-induced QT changes in end-stage renal disease patients. ( Gunderson, BW; Hentges, MJ; Lewis, MJ, 2000) |
| "Ventricular arrhythmias have been associated with both cisapride and hemodialysis (HD)." | 1.31 | Retrospective analysis of the effects of cisapride on the QT interval and QT dispersion in chronic hemodialysis patients. ( Barone, JA; Costeas, C; Mathis, AS, 2001) |
| "Patients with chronic renal failure are often on multiple medications and are at risk for the development of adverse effects from drug interactions." | 1.30 | Torsades de pointes in two chronic renal failure patients treated with cisapride and clarithromycin. ( Sekkarie, MA, 1997) |
| " The pharmacodynamic effect of cisapride was measured by means of radionuclide gastric emptying." | 1.28 | Pharmacokinetics and pharmacodynamics of cisapride in patients undergoing hemodialysis. ( Bares, R; Dakshinamurty, KV; Gladziwa, U; Ittel, TH; Klotz, U; Seiler, KU; Sieberth, HG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marx, M | 1 |
| Kitzmueller, E | 1 |
| Pichler, A | 1 |
| Arbeiter, K | 1 |
| Aufricht, C | 1 |
| Fiskeci, A | 1 |
| Demirçali, A | 1 |
| Arik, N | 1 |
| Sahin, M | 1 |
| Akpolat, T | 1 |
| Bernay, I | 1 |
| Sekkarie, MA | 1 |
| Scott, MK | 1 |
| Kim, MA | 1 |
| Kraus, MA | 1 |
| Mueller, BA | 1 |
| Sehra, RA | 1 |
| Altemose, GT | 1 |
| Sowinski, KM | 1 |
| Hentges, MJ | 1 |
| Gunderson, BW | 1 |
| Lewis, MJ | 1 |
| Silang, R | 1 |
| Regalado, M | 1 |
| Cheng, TH | 1 |
| Wesson, DE | 1 |
| Alimchandani, A | 1 |
| Pai-dhungat, JV | 1 |
| Mathis, AS | 1 |
| Costeas, C | 1 |
| Barone, JA | 1 |
| Gladziwa, U | 1 |
| Bares, R | 1 |
| Klotz, U | 1 |
| Dakshinamurty, KV | 1 |
| Ittel, TH | 1 |
| Seiler, KU | 1 |
| Sieberth, HG | 1 |
| Jenkins, HR | 1 |
| Verrier-Jones, K | 1 |
| Lazarovits, AI | 1 |
| Page, D | 1 |
2 trials available for cisapride and Kidney Failure, Chronic
| Article | Year |
|---|---|
Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying.
Topics: Cisapride; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Humans; Kidney Failure, | 2001 |
A study of gastric emptying in chronic renal failure.
Topics: Adolescent; Adult; Aged; Cisapride; Cross-Over Studies; Double-Blind Method; Erythromycin; Female; G | 1997 |
9 other studies available for cisapride and Kidney Failure, Chronic
| Article | Year |
|---|---|
Effect of cisapride on rate-corrected QT intervals in children on peritoneal dialysis.
Topics: Child; Child, Preschool; Cisapride; Electrocardiography; Female; Gastrointestinal Agents; Humans; In | 2002 |
Effect of cisapride on gastric emptying in haemodialysis patients.
Topics: Adult; Anti-Ulcer Agents; Cisapride; Female; Gastric Emptying; Humans; Kidney Failure, Chronic; Male | 1994 |
Torsades de pointes in two chronic renal failure patients treated with cisapride and clarithromycin.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cisapride; Clarithromycin; Drug Interactions; Female | 1997 |
Effect of cisapride on QT interval in patients with end-stage renal disease.
Topics: Adult; Cisapride; Diabetic Nephropathies; Female; Gastrointestinal Agents; Heart Conduction System; | 2000 |
Retrospective analysis of cisapride-induced QT changes in end-stage renal disease patients.
Topics: Arrhythmias, Cardiac; Cisapride; Diabetic Nephropathies; Electrocardiography; Ethnicity; Female; Gas | 2000 |
Retrospective analysis of the effects of cisapride on the QT interval and QT dispersion in chronic hemodialysis patients.
Topics: Arrhythmias, Cardiac; Cisapride; Contraindications; Drug Interactions; Electrocardiography; Female; | 2001 |
Pharmacokinetics and pharmacodynamics of cisapride in patients undergoing hemodialysis.
Topics: Adult; Aged; Analysis of Variance; Chromatography, Gas; Chromatography, High Pressure Liquid; Cisapr | 1991 |
Vomiting and chronic renal failure.
Topics: Administration, Oral; Cisapride; Gastroesophageal Reflux; Humans; Infant; Kidney Failure, Chronic; P | 1991 |
Intraperitoneal cisapride for the treatment of diabetics with gastroparesis and end-stage renal disease.
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Drug Evaluation; Gastrointestin | 1990 |