Page last updated: 2024-10-25

cisapride and Hyperplasia

cisapride has been researched along with Hyperplasia in 3 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"The serotonin4 (5-HT4) receptor agonists cisapride and/or metoclopramide have been shown to stimulate cortisol secretion in some patients with ACTH-independent bilateral macronodular adrenal hyperplasias (AIMAH) causing Cushing's syndrome."7.72Overexpression of serotonin4 receptors in cisapride-responsive adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia causing Cushing's syndrome. ( Bastard, C; Bertherat, J; Caron, P; Cartier, D; Kuhn, JM; Lacroix, A; Lefebvre, H; Lihrmann, I; Parmentier, F; Tabarin, A; Vaudry, H; Young, J, 2003)
"The serotonin4 (5-HT4) receptor agonists cisapride and/or metoclopramide have been shown to stimulate cortisol secretion in some patients with ACTH-independent bilateral macronodular adrenal hyperplasias (AIMAH) causing Cushing's syndrome."3.72Overexpression of serotonin4 receptors in cisapride-responsive adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia causing Cushing's syndrome. ( Bastard, C; Bertherat, J; Caron, P; Cartier, D; Kuhn, JM; Lacroix, A; Lefebvre, H; Lihrmann, I; Parmentier, F; Tabarin, A; Vaudry, H; Young, J, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feelders, RA1
Lamberts, SW1
Hofland, LJ1
van Koetsveld, PM1
Verhoef-Post, M1
Themmen, AP1
de Jong, FH1
Bonjer, HJ1
Clark, AJ1
van der Lely, AJ1
de Herder, WW1
Cartier, D1
Lihrmann, I1
Parmentier, F1
Bastard, C1
Bertherat, J1
Caron, P1
Kuhn, JM1
Lacroix, A1
Tabarin, A1
Young, J1
Vaudry, H1
Lefebvre, H1
Mannelli, M1
Ferruzzi, P1
Luciani, P1
Crescioli, C1
Buci, L1
Corona, G1
Serio, M1
Peri, A1

Other Studies

3 other studies available for cisapride and Hyperplasia

ArticleYear
Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotr

2003
Overexpression of serotonin4 receptors in cisapride-responsive adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia causing Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Cisapride; Cushing

2003
Cushing's syndrome in a patient with bilateral macronodular adrenal hyperplasia responding to cisapride: an in vivo and in vitro study.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:10

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cisapride; Cushing Syndrome; Female; Gene Expression; H

2003