Page last updated: 2024-10-25

cisapride and Helicobacter Infections

cisapride has been researched along with Helicobacter Infections in 18 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

Research Excerpts

ExcerptRelevanceReference
" pylori infection has an effect on the improvement of dyspeptic symptoms in response to a prokinetic agent, cisapride, in patients with non-ulcer dyspepsia (NUD)."9.11Lack of effect of Helicobacter pylori on symptom improvement with a prokinetic medication, cisapride, in patients with non-ulcer dyspepsia. ( Chaiwatanarat, T; Gonlachanvit, S; Kullavanijaya, P; Mahachai, V, 2005)
"To compare the efficacy of simethicone with placebo and the prokinetic cisapride in patients with functional dyspepsia."9.10A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia. ( Gschossmann, J; Holtmann, G; Mayr, P; Talley, NJ, 2002)
"The aim of this study was to compare symptoms for patients with uninvestigated dyspepsia and a negative Helicobacter pylori serology who were treated with cisapride or placebo."9.09Treatment of uninvestigated dyspepsia with cisapride for patients with negative Helicobacter pylori serologies. ( Avins, AL; Kearney, DJ; McQuaid, KR, 2000)
"Functional dyspepsia is recognized as a common disorder in clinical practice."6.68Cisapride in functional dyspepsia in general practice. A placebo-controlled, randomized, double-blind study. ( de Both, PS; de Groot, GH, 1997)
" pylori infection has an effect on the improvement of dyspeptic symptoms in response to a prokinetic agent, cisapride, in patients with non-ulcer dyspepsia (NUD)."5.11Lack of effect of Helicobacter pylori on symptom improvement with a prokinetic medication, cisapride, in patients with non-ulcer dyspepsia. ( Chaiwatanarat, T; Gonlachanvit, S; Kullavanijaya, P; Mahachai, V, 2005)
"To compare the efficacy of simethicone with placebo and the prokinetic cisapride in patients with functional dyspepsia."5.10A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia. ( Gschossmann, J; Holtmann, G; Mayr, P; Talley, NJ, 2002)
"The aim of this study was to compare symptoms for patients with uninvestigated dyspepsia and a negative Helicobacter pylori serology who were treated with cisapride or placebo."5.09Treatment of uninvestigated dyspepsia with cisapride for patients with negative Helicobacter pylori serologies. ( Avins, AL; Kearney, DJ; McQuaid, KR, 2000)
"Functional dyspepsia is recognized as a common disorder in clinical practice."2.68Cisapride in functional dyspepsia in general practice. A placebo-controlled, randomized, double-blind study. ( de Both, PS; de Groot, GH, 1997)
"Non-ulcer dyspepsia is common and is often confused with other diagnoses."2.42Update on the role of drug therapy in non-ulcer dyspepsia. ( Talley, NJ, 2003)
"Dyspepsia is most optimally defined as pain or discomfort centred in the upper abdomen."2.40Management guidelines for uninvestigated and functional dyspepsia in the Asia-Pacific region: First Asian Pacific Working Party on Functional Dyspepsia. ( Fock, KM; Goh, KL; Lam, SK; Talley, NJ, 1998)
"Dyspepsia affects one in four Australians; of those who present in general practice, the majority will have functional or non-ulcer dyspepsia, with no structural explanation for their symptoms."2.39Modern management of dyspepsia. ( Talley, NJ, 1996)
"Functional dyspepsia is one of the most common functional disorders of the gastrointestinal tract, which resulted from impaired motor skills, visceral hypersensitivity, increased mucosal permeability, disorders of the autonomic nervous system, etc."1.62[Rational treatment of patients with functional dyspepsia]. ( Kazakov, AS; Nasretdinova, EK; Ushkalova, EA; Zyryanov, SK, 2021)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (44.44)18.2507
2000's9 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Kazakov, AS1
Zyryanov, SK1
Ushkalova, EA1
Nasretdinova, EK1
Holtmann, G2
Gschossmann, J1
Mayr, P1
Talley, NJ5
Buzás, GM1
Gonlachanvit, S1
Mahachai, V1
Chaiwatanarat, T1
Kullavanijaya, P1
Ang, TL1
Fock, KM2
Teo, EK1
Chan, YH1
Ng, TM1
Chua, TS1
Tan, JY1
Frazzoni, M1
Lonardo, A1
Grisendi, A1
Della Casa, G1
Pulvirenti, M1
Ferrari, AM1
Di Gregorio, C1
Melini, L1
Hudziak, H1
de Groot, GH1
de Both, PS1
Lam, SK1
Goh, KL1
Chassany, O1
Douet, MC1
Ducrot, F1
Kearney, DJ1
Avins, AL1
McQuaid, KR1
Radwan, P1
Grodzieński, R1
Zaorska-Rajca, J1
Skrzydło-Radomańska, B1
Słomka, M1
Wysokiński, A1
Hansen, JM1
Bytzer, P1
Spiroglou, K1
Chatziparasidis, G1
Paroutoglou, G1
Demertzidou, V1
Giouleme, O1
Nikolaides, N1
Evgenides, N1

Reviews

6 reviews available for cisapride and Helicobacter Infections

ArticleYear
Update on the role of drug therapy in non-ulcer dyspepsia.
    Reviews in gastroenterological disorders, 2003,Winter, Volume: 3, Issue:1

    Topics: Anti-Ulcer Agents; Antidepressive Agents, Tricyclic; Cisapride; Dopamine Antagonists; Dyspepsia; Gas

2003
Functional dyspepsia. Current treatment recommendations.
    Drugs, 1993, Volume: 45, Issue:6

    Topics: Cisapride; Dopamine Antagonists; Dyspepsia; Gastric Acid; Gastrointestinal Agents; Gastrointestinal

1993
Modern management of dyspepsia.
    Australian family physician, 1996, Volume: 25, Issue:1

    Topics: Adult; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bismuth; Child; C

1996
[Treatment of stomach ulcer].
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:1 Pt 2

    Topics: Anti-Ulcer Agents; Cisapride; Drug Resistance; Helicobacter Infections; Histamine H2 Antagonists; Hu

1996
Management guidelines for uninvestigated and functional dyspepsia in the Asia-Pacific region: First Asian Pacific Working Party on Functional Dyspepsia.
    Journal of gastroenterology and hepatology, 1998, Volume: 13, Issue:4

    Topics: Antiemetics; Asia; Cisapride; Disease Management; Domperidone; Dyspepsia; Endoscopy; Gastrointestina

1998
[Gastroesophageal reflux in adults: diagnosis and treatment. Conclusions of Consensus Conference: long text. Organized by the French National Society of Gastroenterology and Belgian Royal Society of Gastroenterology/Flemish Society of Gastroenterology. Fr
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:1

    Topics: Adult; Age Factors; Antacids; Anti-Ulcer Agents; Cisapride; Clinical Trials as Topic; Diagnosis, Dif

1999

Trials

7 trials available for cisapride and Helicobacter Infections

ArticleYear
A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:9

    Topics: Adult; Aged; Cisapride; Double-Blind Method; Dyspepsia; Female; Gastrointestinal Agents; Health Stat

2002
Lack of effect of Helicobacter pylori on symptom improvement with a prokinetic medication, cisapride, in patients with non-ulcer dyspepsia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:5

    Topics: Adult; Cholinergic Agonists; Cisapride; Drug Administration Schedule; Dyspepsia; Female; Gastric Emp

2005
Helicobacter pylori eradication versus prokinetics in the treatment of functional dyspepsia: a randomized, double-blind study.
    Journal of gastroenterology, 2006, Volume: 41, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Infective Agents; Cisapride; Clari

2006
Are routine duodenal and antral biopsies useful in the management of "functional" dyspepsia? A diagnostic and therapeutic study.
    Journal of clinical gastroenterology, 1993, Volume: 17, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Bismuth; Cisapride; Double-Blind Method; Du

1993
Cisapride in functional dyspepsia in general practice. A placebo-controlled, randomized, double-blind study.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Cisapride; Diagnosis, Differential; Double-Blind Method;

1997
Treatment of uninvestigated dyspepsia with cisapride for patients with negative Helicobacter pylori serologies.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:9

    Topics: Administration, Oral; Adult; Antibodies, Bacterial; Cisapride; Diagnosis, Differential; Dyspepsia; F

2000
[The effect of prokinetic treatment and eradication of Helicobacter pylori on gastric emptying and symptoms of functional dyspepsia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2001, Volume: 54, Issue:1-2

    Topics: Adolescent; Adult; Cisapride; Drug Therapy, Combination; Dyspepsia; Famotidine; Female; Gastric Empt

2001

Other Studies

5 other studies available for cisapride and Helicobacter Infections

ArticleYear
[Rational treatment of patients with functional dyspepsia].
    Terapevticheskii arkhiv, 2021, Aug-15, Volume: 93, Issue:8

    Topics: Antidepressive Agents, Tricyclic; Cisapride; Domperidone; Dyspepsia; Helicobacter Infections; Humans

2021
[The effect of Helicobacter pylori eradication on prokinetic treatment on the quality of life in functional dyspepsia].
    Orvosi hetilap, 2004, Oct-17, Volume: 145, Issue:42

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Benzimidazoles

2004
[What are the results of medical treatments?].
    Revue medicale de Bruxelles, 1999, Volume: 20, Issue:2

    Topics: Antacids; Cisapride; Gastroesophageal Reflux; Gastrointestinal Agents; Helicobacter Infections; Heli

1999
[Drug therapy of functional dyspepsia. A review based on Cochrane Reviews].
    Ugeskrift for laeger, 2001, Sep-10, Volume: 163, Issue:37

    Topics: Antacids; Cisapride; Databases, Bibliographic; Dyspepsia; Evidence-Based Medicine; Gastrointestinal

2001
Functional dyspepsia in children.
    Journal of pediatric gastroenterology and nutrition, 2001, Volume: 33, Issue:4

    Topics: Adolescent; Anti-Ulcer Agents; Child; Child, Preschool; Cisapride; Diagnosis, Differential; Dyspepsi

2001