cisapride has been researched along with Heart Failure in 2 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In responses to all three QT-lengthening compounds, RR, QT and QTc(F) lengthened similarly in a dose-response manner in both the failing and normal hearts." | 1.38 | Assessment of QT-prolonging drugs in the isolated normal and failing rabbit hearts. ( Hamlin, RL; Kijtawornrat, A; Sawangkoon, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kijtawornrat, A | 1 |
| Sawangkoon, S | 1 |
| Hamlin, RL | 1 |
| Kubler, PA | 1 |
| Pillans, PI | 1 |
| McKay, JR | 1 |
2 other studies available for cisapride and Heart Failure
| Article | Year |
|---|---|
Assessment of QT-prolonging drugs in the isolated normal and failing rabbit hearts.
Topics: Animals; Arrhythmias, Cardiac; Cisapride; Electrocardiography; Feasibility Studies; Glucose; Heart; | 2012 |
Possible interaction between cisapride and digoxin.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Cisapride; Digoxin; Drug Interactions; Female; Gast | 2001 |