cisapride has been researched along with Gastric Ulcer in 14 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination of cisapride and ranitidine in the treatment of gastric ulcer did not enhance the healing rate or improve symptom relief in patients treated for uncomplicated gastric ulcer when compared with the monotherapies." | 9.08 | The effect of cisapride and ranitidine as monotherapies and in combination in the treatment of uncomplicated gastric ulceration. ( Glise, H; Hallerbäck, B; Solhaug, JH; Stubberöd, A, 1995) |
| "A double-blind, randomized, parallel-group multicenter study was conducted in 120 patients with gastric ulcer to compare cisapride, 10 mg t." | 9.07 | Prokinetic drug treatment (cisapride) is as effective as H2-blocking agent (ranitidine) in the treatment of gastric ulcer. ( Bergemann, W; Bouzo, H; Hotz, F; Hüttemann, W; Müller, P; Rösch, W; Simon, B, 1991) |
| " The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "Apnea in the neonatal period frequently is associated with prematurity." | 7.70 | Gastric ulcer presenting as gastroesophageal reflux and apnea in a term neonate. ( Biskinis, EK; Naqvi, M; Skinner, S, 1998) |
| "Combination of cisapride and ranitidine in the treatment of gastric ulcer did not enhance the healing rate or improve symptom relief in patients treated for uncomplicated gastric ulcer when compared with the monotherapies." | 5.08 | The effect of cisapride and ranitidine as monotherapies and in combination in the treatment of uncomplicated gastric ulceration. ( Glise, H; Hallerbäck, B; Solhaug, JH; Stubberöd, A, 1995) |
| "A double-blind, randomized, parallel-group multicenter study was conducted in 120 patients with gastric ulcer to compare cisapride, 10 mg t." | 5.07 | Prokinetic drug treatment (cisapride) is as effective as H2-blocking agent (ranitidine) in the treatment of gastric ulcer. ( Bergemann, W; Bouzo, H; Hotz, F; Hüttemann, W; Müller, P; Rösch, W; Simon, B, 1991) |
| " The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "Apnea in the neonatal period frequently is associated with prematurity." | 3.70 | Gastric ulcer presenting as gastroesophageal reflux and apnea in a term neonate. ( Biskinis, EK; Naqvi, M; Skinner, S, 1998) |
| " The antiulcerogenic effects of cisapride, a potent benzamide-stimulating gastrointestinal motility agent, were studied on cold-resistant and pylorus-ligated gastric ulcers." | 3.69 | Effects of cisapride on ulcer formation and gastric secretion in rats: comparison with ranitidine and omeprazol. ( Alarcón de la Lastra, C; La Casa, M; López, A; Martin, MJ; Motilva, V, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (85.71) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahattanadul, S | 1 |
| Ridtitid, W | 1 |
| Nima, S | 1 |
| Phdoongsombut, N | 1 |
| Ratanasuwon, P | 1 |
| Kasiwong, S | 1 |
| Zou, K | 1 |
| Liu, S | 1 |
| Liu, J | 1 |
| Liu, Y | 1 |
| Hou, X | 1 |
| Yi, C | 1 |
| Stubberöd, A | 1 |
| Glise, H | 1 |
| Hallerbäck, B | 1 |
| Solhaug, JH | 1 |
| Testoni, PA | 1 |
| Bagnolo, F | 1 |
| Buizza, M | 1 |
| Masci, E | 1 |
| Toti, GL | 1 |
| Spinelli, A | 1 |
| Manzi, G | 1 |
| López, A | 3 |
| Motilva, V | 3 |
| Alarcón de la Lastra, C | 3 |
| Martín, MJ | 3 |
| La Casa, C | 2 |
| Hudziak, H | 1 |
| Takeuchi, K | 1 |
| Kato, S | 1 |
| Hirata, T | 1 |
| Nishiwaki, H | 1 |
| La Casa, M | 1 |
| Skinner, S | 1 |
| Naqvi, M | 1 |
| Biskinis, EK | 1 |
| Jian, R | 1 |
| Simon, B | 2 |
| Bergemann, W | 1 |
| Bouzo, H | 1 |
| Hüttemann, W | 1 |
| Hotz, F | 1 |
| Müller, P | 2 |
| Rösch, W | 1 |
| Nonnenmacher, A | 1 |
| Dammann, HG | 1 |
2 reviews available for cisapride and Gastric Ulcer
| Article | Year |
|---|---|
[Treatment of stomach ulcer].
Topics: Anti-Ulcer Agents; Cisapride; Drug Resistance; Helicobacter Infections; Histamine H2 Antagonists; Hu | 1996 |
[Disorders of gastric emptying].
Topics: Cisapride; Diabetes Complications; Domperidone; Dyspepsia; Gastric Emptying; Gastroesophageal Reflux | 1992 |
6 trials available for cisapride and Gastric Ulcer
| Article | Year |
|---|---|
Study on gastric empty disorder after the gastric ulcer healing and therapeutic effect of cisapride.
Topics: Adult; Aged; Anti-Ulcer Agents; Cisapride; Female; Gastric Emptying; Humans; Male; Middle Aged; Stom | 2000 |
The effect of cisapride and ranitidine as monotherapies and in combination in the treatment of uncomplicated gastric ulceration.
Topics: Anti-Ulcer Agents; Cisapride; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combi | 1995 |
Effectiveness of cisapride in gastric ulcer. Results of a double-blind randomized trial versus ranitidine and versus cisapride plus ranitidine.
Topics: Adult; Aged; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Drug Therapy, Combination; Female; H | 1993 |
Prokinetic drug treatment (cisapride) is as effective as H2-blocking agent (ranitidine) in the treatment of gastric ulcer.
Topics: Adult; Aged; Cisapride; Double-Blind Method; Female; Gastrointestinal Motility; Gastroscopy; Humans; | 1991 |
[Treatment of chronic-obstructive upper abdominal complaints. Outlook. Further hypothetical indications].
Topics: Cisapride; Clinical Trials as Topic; Constipation; Dyspepsia; Gastroesophageal Reflux; Gastrointesti | 1990 |
[Gastroprokinetics in the treatment of stomach ulcer: a direct comparative study of cisapride versus ranitidine].
Topics: Adult; Aged; Cisapride; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperidines; Randomi | 1990 |
6 other studies available for cisapride and Gastric Ulcer
| Article | Year |
|---|---|
Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Biomarkers; Cisapride; Disease Models | 2011 |
The role of gastric mucosal sulphydryls in the ulcer-protecting effects of cisapride.
Topics: Animals; Anti-Ulcer Agents; Cisapride; Disease Models, Animal; Ethanol; Ethylmaleimide; Gastric Muco | 1996 |
Cytoprotective activity of cisapride on experimental gastric mucosal lesions induced by ethanol. Role of endogenous prostaglandins.
Topics: Animals; Anti-Ulcer Agents; Cisapride; Dinoprostone; Ethanol; Gastric Mucosa; Indomethacin; Male; Mu | 1996 |
Gastric motility and mucosal ulcerogenic responses induced by prokinetic drugs in rats under prostaglandin-deficient conditions.
Topics: Animals; Cisapride; Dose-Response Relationship, Drug; Gastric Acid; Gastric Emptying; Gastric Mucosa | 1997 |
Effects of cisapride on ulcer formation and gastric secretion in rats: comparison with ranitidine and omeprazol.
Topics: Animals; Anti-Ulcer Agents; Cisapride; Gastric Juice; Gastric Mucosa; Histamine Release; Ligation; M | 1996 |
Gastric ulcer presenting as gastroesophageal reflux and apnea in a term neonate.
Topics: Anti-Ulcer Agents; Apnea; Cisapride; Esophagus; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concen | 1998 |