cisapride has been researched along with Gastric Diseases in 28 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the therapeutic effect of cisapride on gastric injury following hemorrhagic shock resuscitation." | 7.73 | Therapeutic effect of cisapride on gastric injury following hemorrhagic shock resuscitation in rats. ( Wang, ZG; Xu, Y; Zhang, LY; Zhu, PF, 2005) |
| "A case of chronic intestinal pseudoobstruction secondary to systemic amyloidosis in a patient with multiple myeloma is described." | 5.28 | Intestinal pseudoobstruction secondary to amyloidosis responsive to cisapride. ( Arthur, JF; Fraser, AG; Hamilton, I, 1991) |
| "We conducted a 12-month trial of cisapride (10 mg three times a day) in 21 patients with gastric stasis due to clinically and manometrically diagnosed gastroparesis (N = 9; seven due to diabetes) or chronic intestinal pseudo-obstruction (N = 12)." | 5.07 | Long-term efficacy of oral cisapride in symptomatic upper gut dysmotility. ( Abell, TL; Camilleri, M; DiMagno, EP; Hench, VS; Malagelada, JR; Zinsmeister, AR, 1991) |
| "In a double blind crossover comparison with placebo, the effects of cisapride (10 mg tid for two weeks), a non-antidopaminergic gastrointestinal prokinetic drug, on gastric emptying times and on symptoms were evaluated in 12 patients with chronic idiopathic dyspepsia and gastroparesis." | 5.06 | Effect of chronic administration of cisapride on gastric emptying of a solid meal and on dyspeptic symptoms in patients with idiopathic gastroparesis. ( Barbara, L; Corinaldesi, R; Raiti, C; Rea, E; Salgemini, R; Stanghellini, V, 1987) |
| "To investigate the therapeutic effect of cisapride on gastric injury following hemorrhagic shock resuscitation." | 3.73 | Therapeutic effect of cisapride on gastric injury following hemorrhagic shock resuscitation in rats. ( Wang, ZG; Xu, Y; Zhang, LY; Zhu, PF, 2005) |
| "Cisapride has an established prokinetic effect in patients with delayed gastric emptying." | 2.68 | The effect of a single rectal dose of cisapride on delayed gastric emptying. ( Brummer, RJ; Heidendal, GA; Kemerink, GJ; Sanders, DG; Schoenmakers, EA; Stockbrügger, RW, 1997) |
| "The aim of this study was to determine the optimal dosage regimen of cisapride for the treatment of idiopathic gastroparesis." | 2.67 | The effect of different dosage schedules of cisapride on gastric emptying in idiopathic gastroparesis. ( Barbara, L; Corbelli, C; Corinaldesi, R; Marengo, M; Monetti, N; Rea, E; Stanghellini, V; Tosetti, C, 1993) |
| " While both cisapride and metoclopramide normalized impaired solid emptying, cisapride at its highest dosage (10 mg) resulted in significantly faster gastric emptying (P = 0." | 2.67 | Cisapride vs metoclopramide. An acute study in diabetic gastroparesis. ( Diamant, NE; Lico, S; McHugh, S, 1992) |
| "Vomiting was the first cause of admission in diabetics." | 1.29 | Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. ( Gallar, P; Guijo, G; Oliet, A; Ortega, O; Vigil, A, 1993) |
| "A case of chronic intestinal pseudoobstruction secondary to systemic amyloidosis in a patient with multiple myeloma is described." | 1.28 | Intestinal pseudoobstruction secondary to amyloidosis responsive to cisapride. ( Arthur, JF; Fraser, AG; Hamilton, I, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.86) | 18.7374 |
| 1990's | 22 (78.57) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, LY | 1 |
| Wang, ZG | 1 |
| Zhu, PF | 1 |
| Xu, Y | 1 |
| Dworkin, BM | 1 |
| Rosenthal, WS | 1 |
| Casellas, AR | 1 |
| Girolomo, R | 1 |
| Lebovics, E | 1 |
| Freeman, S | 1 |
| Clark, SB | 1 |
| Kendall, BJ | 1 |
| McCallum, RW | 3 |
| Fraser, RJ | 1 |
| Horowitz, M | 2 |
| Maddox, AF | 1 |
| Dent, J | 1 |
| Rothstein, RD | 1 |
| Alavi, A | 1 |
| Reynolds, JC | 2 |
| Corinaldesi, R | 2 |
| Stanghellini, V | 2 |
| Tosetti, C | 1 |
| Rea, E | 2 |
| Corbelli, C | 1 |
| Marengo, M | 1 |
| Monetti, N | 1 |
| Barbara, L | 2 |
| Hill, AD | 1 |
| Walsh, TN | 1 |
| Hamilton, D | 1 |
| Freyne, P | 1 |
| O'Hare, N | 1 |
| Byrne, PJ | 1 |
| Hennessy, TP | 1 |
| Gallar, P | 1 |
| Oliet, A | 1 |
| Vigil, A | 1 |
| Ortega, O | 1 |
| Guijo, G | 1 |
| Richards, RD | 1 |
| Valenzuela, GA | 1 |
| Davenport, KG | 1 |
| Fisher, KL | 1 |
| Kawagishi, T | 1 |
| Nishizawa, Y | 1 |
| Okuno, Y | 1 |
| Sekiya, K | 1 |
| Morii, H | 1 |
| Sternberg, A | 1 |
| Coscas, D | 1 |
| Fireman, Z | 1 |
| Czambor-Ksiazek, E | 1 |
| Pokrzywnicki, W | 1 |
| Grzeszczak, W | 1 |
| Duda, G | 1 |
| Brummer, RJ | 1 |
| Schoenmakers, EA | 1 |
| Kemerink, GJ | 1 |
| Heidendal, GA | 1 |
| Sanders, DG | 1 |
| Stockbrügger, RW | 1 |
| Vitola, J | 1 |
| Vukanovic, J | 1 |
| Roden, DM | 1 |
| Hall, JA | 1 |
| Washabau, RJ | 1 |
| Chaabouni, H | 1 |
| Cheikh, I | 1 |
| el Mokhtar, M | 1 |
| Ben Ammar, A | 1 |
| Drenth, JP | 1 |
| Engels, LG | 1 |
| Jian, R | 1 |
| McHugh, S | 1 |
| Lico, S | 1 |
| Diamant, NE | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Fraser, AG | 1 |
| Arthur, JF | 1 |
| Hamilton, I | 1 |
| Abell, TL | 1 |
| Camilleri, M | 1 |
| DiMagno, EP | 1 |
| Hench, VS | 1 |
| Zinsmeister, AR | 1 |
| Malagelada, JR | 1 |
| Roberts, AP | 1 |
| Cullen, PT | 1 |
| Campbell, FC | 1 |
| Ricci, DA | 1 |
| Vogelberg, KH | 1 |
| Dalügge, A | 1 |
| Raiti, C | 1 |
| Salgemini, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for cisapride and Gastric Diseases
| Article | Year |
|---|---|
Gastroparesis and the current use of prokinetic drugs.
Topics: Cisapride; Domperidone; Gastric Emptying; Humans; Metoclopramide; Piperidines; Stomach Diseases | 1993 |
[Disorders of gastric emptying in diabetes. II. Treatment].
Topics: Cisapride; Diabetes Complications; Domperidone; Dopamine Agents; Erythromycin; Gastric Emptying; Hum | 1997 |
Diagnosis and treatment of gastric motility disorders.
Topics: Animals; Cat Diseases; Cats; Cisapride; Dog Diseases; Dogs; Erythromycin; Gastric Emptying; Gastroin | 1999 |
Diabetic gastroparesis. A critical reappraisal of new treatment strategies.
Topics: Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes | 1992 |
[Disorders of gastric emptying].
Topics: Cisapride; Diabetes Complications; Domperidone; Dyspepsia; Gastric Emptying; Gastroesophageal Reflux | 1992 |
Prokinetic agents: a key in the future of gastroenterology.
Topics: Biomechanical Phenomena; Cisapride; Domperidone; Forecasting; Gastroenterology; Gastroesophageal Ref | 1989 |
Diagnosis and treatment of delayed gastric emptying.
Topics: Anemia, Pernicious; Anorexia Nervosa; Cisapride; Connective Tissue Diseases; Diabetes Complications; | 1988 |
9 trials available for cisapride and Gastric Diseases
| Article | Year |
|---|---|
Open label study of long-term effectiveness of cisapride in patients with idiopathic gastroparesis.
Topics: Adult; Anti-Ulcer Agents; Cisapride; Female; Gastric Emptying; Humans; Male; Paresis; Piperidines; S | 1994 |
The effect of different dosage schedules of cisapride on gastric emptying in idiopathic gastroparesis.
Topics: Adult; Cisapride; Double-Blind Method; Drug Administration Schedule; Eating; Female; Gastric Emptyin | 1993 |
Objective and subjective results of a randomized, double-blind, placebo-controlled trial using cisapride to treat gastroparesis.
Topics: Adolescent; Adult; Aged; Cisapride; Double-Blind Method; Female; Gastric Emptying; Humans; Male; Mid | 1993 |
Effect of cisapride on gastric emptying of indigestible solids and plasma motilin concentration in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Cisapride; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1993 |
The effect of a single rectal dose of cisapride on delayed gastric emptying.
Topics: Administration, Rectal; Adult; Aged; Cisapride; Cross-Over Studies; Double-Blind Method; Female; Gas | 1997 |
Diabetic gastroparesis. A critical reappraisal of new treatment strategies.
Topics: Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes | 1992 |
Cisapride vs metoclopramide. An acute study in diabetic gastroparesis.
Topics: Adult; Autonomic Nervous System Diseases; Cisapride; Diabetic Neuropathies; Dose-Response Relationsh | 1992 |
Long-term efficacy of oral cisapride in symptomatic upper gut dysmotility.
Topics: Administration, Oral; Adult; Body Weight; Chronic Disease; Cisapride; Double-Blind Method; Female; G | 1991 |
Effect of chronic administration of cisapride on gastric emptying of a solid meal and on dyspeptic symptoms in patients with idiopathic gastroparesis.
Topics: Adult; Cisapride; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Female; Gastric Emptying | 1987 |
13 other studies available for cisapride and Gastric Diseases
| Article | Year |
|---|---|
Therapeutic effect of cisapride on gastric injury following hemorrhagic shock resuscitation in rats.
Topics: Animals; Cisapride; Disease Models, Animal; Gastric Emptying; Gastric Mucosa; Gastrointestinal Agent | 2005 |
Postprandial antropyloroduodenal motility and gastric emptying in gastroparesis--effects of cisapride.
Topics: Adult; Aged; Cisapride; Clinical Protocols; Duodenum; Female; Gastric Emptying; Gastrointestinal Mot | 1994 |
Electrogastrography in patients with gastroparesis and effect of long-term cisapride.
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Electromyography; Electrophysiology; Gastric Emptying; | 1993 |
Erythromycin improves emptying of the denervated stomach after oesophagectomy.
Topics: Aged; Cisapride; Erythromycin; Esophageal Neoplasms; Esophagectomy; Female; Gastric Emptying; Humans | 1993 |
Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin.
Topics: Cisapride; Diabetes Mellitus, Type 1; Erythromycin; Female; Gastric Emptying; Hospitalization; Human | 1993 |
[Gastric phytobezoar].
Topics: Adult; Anti-Ulcer Agents; Bezoars; Cellulose; Cisapride; Dietary Fiber; Domperidone; Endoscopy; Frui | 1996 |
Cisapride-induced torsades de pointes.
Topics: Adolescent; Anti-Bacterial Agents; Biotransformation; Cisapride; Electrocardiography; Female; Follow | 1998 |
[Gastric motility disorders].
Topics: Cisapride; Diagnosis, Differential; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Moti | 1999 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Intestinal pseudoobstruction secondary to amyloidosis responsive to cisapride.
Topics: Amyloidosis; Cisapride; Female; Humans; Intestinal Diseases; Intestinal Pseudo-Obstruction; Middle A | 1991 |
Long-term efficacy of cisapride in diabetic gastroparesis.
Topics: Cisapride; Diabetes Mellitus, Type 1; Gastric Emptying; Humans; Male; Middle Aged; Piperidines; Sero | 1990 |
Cisapride in postoperative gastroparesis.
Topics: Acute Disease; Cisapride; Female; Humans; Middle Aged; Paralysis; Piperidines; Postoperative Complic | 1987 |
[Sonographic studies during drug treatment of diabetic gastroparesis].
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastric Emptying; Gastro | 1988 |