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cisapride and Gall Bladder Diseases

cisapride has been researched along with Gall Bladder Diseases in 2 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
" Gallbladder contractility, measured in vitro in response to CCK, decreased 23% in animals on the 1% cholesterol diet; cisapride restored the CCK dose-response curve to normal."5.29Cisapride improves gallbladder contractility and bile lipid composition in an animal model of gallstone disease. ( Shaffer, EA; Xu, QW, 1993)
"Cisapride treatment reversed the gallbladder hypomotility within the normal range while placebo did not change the response to meal."2.67Gallbladder hypokinesia and normal gastric emptying of liquids in patients with dyspeptic symptoms. A double-blind placebo-controlled clinical trial with cisapride. ( Cuccurullo, F; DiFelice, F; Imbimbo, B; Laico, MG; Lapenna, D; Marzio, L, 1992)
" Gallbladder contractility, measured in vitro in response to CCK, decreased 23% in animals on the 1% cholesterol diet; cisapride restored the CCK dose-response curve to normal."1.29Cisapride improves gallbladder contractility and bile lipid composition in an animal model of gallstone disease. ( Shaffer, EA; Xu, QW, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, QW1
Shaffer, EA1
Marzio, L1
DiFelice, F1
Laico, MG1
Imbimbo, B1
Lapenna, D1
Cuccurullo, F1

Trials

1 trial available for cisapride and Gall Bladder Diseases

ArticleYear
Gallbladder hypokinesia and normal gastric emptying of liquids in patients with dyspeptic symptoms. A double-blind placebo-controlled clinical trial with cisapride.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:2

    Topics: Adult; Cisapride; Double-Blind Method; Dyspepsia; Female; Gallbladder Diseases; Gallbladder Emptying

1992

Other Studies

1 other study available for cisapride and Gall Bladder Diseases

ArticleYear
Cisapride improves gallbladder contractility and bile lipid composition in an animal model of gallstone disease.
    Gastroenterology, 1993, Volume: 105, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Carbon Radioisotopes; Cholecystokinin; Cholelithiasis; Choleste

1993