cisapride has been researched along with Fecal Incontinence in 7 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Fecal Incontinence: Failure of voluntary control of the anal sphincters, with involuntary passage of feces and flatus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether cisapride is effective in the treatment of children with constipation." | 9.09 | Cisapride for the treatment of constipation in children: A double-blind study. ( Garcia-Aranda, JA; Nurko, S; Worona, LB; Zlochisty, O, 2000) |
| "To determine whether cisapride is effective in the treatment of children with constipation." | 5.09 | Cisapride for the treatment of constipation in children: A double-blind study. ( Garcia-Aranda, JA; Nurko, S; Worona, LB; Zlochisty, O, 2000) |
| "Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease." | 4.90 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Cody, JD; Coggrave, M; Norton, C, 2014) |
| "Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease." | 4.89 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C, 2013) |
| " Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (three trials)." | 4.83 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C; Wiesel, PH, 2006) |
| " Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (two trials)." | 4.81 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Brazzelli, M; Norton, C; Wiesel, PH, 2001) |
| "This paper provides a comprehensive review of the current knowledge on cisapride in different clinical conditions in children: different manifestations of gastro-oesophageal reflux, such as (excessive) regurgitation, oesophagitis, chronic respiratory disease or uncontrolled asthma, cystic fibrosis, chronic dyspepsia, constipation and pseudo-obstruction, and as an aid to small bowel capsule-biopsy." | 4.80 | Clinical use of cisapride and its risk-benefit in paediatric patients. ( Vandenplas, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coggrave, M | 3 |
| Norton, C | 4 |
| Cody, JD | 1 |
| Wiesel, PH | 2 |
| Vandenplas, Y | 1 |
| Fernández-Fernández, FJ | 1 |
| González-González, C | 1 |
| Castro-Alvariño, J | 1 |
| Sesma, P | 1 |
| Nurko, S | 1 |
| Garcia-Aranda, JA | 1 |
| Worona, LB | 1 |
| Zlochisty, O | 1 |
| Brazzelli, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neurogenic Bowel Dysfunction: Evaluation of the Effects of Osteopathic Manipulative Treatment in People With Central Nervous System Injury[NCT04127617] | 70 participants (Anticipated) | Interventional | 2019-10-28 | Recruiting | |||
| Automatic Colon-specific Massage With MOWOOT Medical Device to Treat Chronic Constipation in Adults[NCT04262752] | 100 participants (Actual) | Interventional | 2018-01-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for cisapride and Fecal Incontinence
| Article | Year |
|---|---|
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Adult; Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestina | 2013 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2014 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2006 |
Clinical use of cisapride and its risk-benefit in paediatric patients.
Topics: Child; Child, Preschool; Cisapride; Constipation; Cystic Fibrosis; Drug Interactions; Dyspepsia; Fec | 1998 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2001 |
1 trial available for cisapride and Fecal Incontinence
| Article | Year |
|---|---|
Cisapride for the treatment of constipation in children: A double-blind study.
Topics: Adolescent; Analysis of Variance; Cathartics; Chi-Square Distribution; Child; Child, Preschool; Chro | 2000 |
1 other study available for cisapride and Fecal Incontinence
| Article | Year |
|---|---|
[Cisapride in idiopathic megacolon-megarectum].
Topics: Adolescent; Chronic Disease; Cisapride; Combined Modality Therapy; Diarrhea; Dilatation, Pathologic; | 1999 |