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cisapride and Esophagitis

cisapride has been researched along with Esophagitis in 11 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of cisapride, a selective 5-hydroxytryptamine-4 receptor agonist, on the frequency of nocturnal transient lower oesophageal sphincter relaxations and oesophageal acid exposure in patients with gastro-oesophageal reflux disease."9.10Effect of cisapride on nocturnal transient lower oesophageal sphincter relaxations and nocturnal gastro-oesophageal reflux in patients with oesophagitis: a double-blind, placebo-controlled study. ( McCallum, R; Olyaee, M; Pehlivanov, N; Sarosiek, I; Whitman, R, 2002)
"Following endoscopy 424 patients presenting with heartburn as the predominant symptom of gastro-oesophageal reflux disease were randomized to treatment with omeprazole 20 or 10 mg once daily, or cisapride 10 mg four times daily, in a double-blind, double-dummy, parallel group, multicentre study."9.08Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride. ( Barthelemy, P; Galmiche, JP; Hamelin, B, 1997)
"In a double-blind, randomized, comparative trial of the prokinetic drug cisapride and the H2-blocker cimetidine, mucosal healing and changes in symptoms of gastroesophageal reflux were evaluated in patients with erosive reflux esophagitis."9.06Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis. ( Evreux, M; Filoche, B; Fournet, J; Fraitag, B; Galmiche, JP; Soule, JC; Vitaux, J; Zeitoun, P, 1990)
"To investigate the effect of cisapride, a selective 5-hydroxytryptamine-4 receptor agonist, on the frequency of nocturnal transient lower oesophageal sphincter relaxations and oesophageal acid exposure in patients with gastro-oesophageal reflux disease."5.10Effect of cisapride on nocturnal transient lower oesophageal sphincter relaxations and nocturnal gastro-oesophageal reflux in patients with oesophagitis: a double-blind, placebo-controlled study. ( McCallum, R; Olyaee, M; Pehlivanov, N; Sarosiek, I; Whitman, R, 2002)
"Following endoscopy 424 patients presenting with heartburn as the predominant symptom of gastro-oesophageal reflux disease were randomized to treatment with omeprazole 20 or 10 mg once daily, or cisapride 10 mg four times daily, in a double-blind, double-dummy, parallel group, multicentre study."5.08Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride. ( Barthelemy, P; Galmiche, JP; Hamelin, B, 1997)
"In a double-blind, randomized, comparative trial of the prokinetic drug cisapride and the H2-blocker cimetidine, mucosal healing and changes in symptoms of gastroesophageal reflux were evaluated in patients with erosive reflux esophagitis."5.06Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis. ( Evreux, M; Filoche, B; Fournet, J; Fraitag, B; Galmiche, JP; Soule, JC; Vitaux, J; Zeitoun, P, 1990)
"Gastroesophageal reflux (GER) may aggravate chronic bronchopulmonary diseases."1.31Frequency, consequences and pharmacological treatment of gastroesophageal reflux in children with cystic fibrosis. ( Brodzicki, J; Korzon, M; Trawińska-Bartnicka, M, 2002)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's7 (63.64)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodzicki, J1
Trawińska-Bartnicka, M1
Korzon, M1
Lindahl, H1
Rintala, R1
Vandenplas, Y1
Ashkenazi, A1
Belli, D1
Boige, N1
Bouquet, J1
Cadranel, S1
Cezard, JP1
Cucchiara, S1
Dupont, C1
Geboes, K1
Dieckmann, K1
Maurage, C1
Rolland, JC1
Ramponi, N1
Jonville, AP1
Galmiche, JP3
Barthelemy, P1
Hamelin, B1
Pehlivanov, N1
Sarosiek, I1
Whitman, R1
Olyaee, M1
McCallum, R1
Denié, C1
Gohy, P1
Allen, ML1
McIntosh, DL1
Robinson, MG1
Fraitag, B2
Filoche, B1
Evreux, M1
Vitaux, J1
Zeitoun, P1
Fournet, J1
Soule, JC1
Cloarec, D1

Reviews

2 reviews available for cisapride and Esophagitis

ArticleYear
A proposition for the diagnosis and treatment of gastro-oesophageal reflux disease in children: a report from a working group on gastro-oesophageal reflux disease. Working Group of the European Society of Paediatric Gastro-enterology and Nutrition (ESPGAN
    European journal of pediatrics, 1993, Volume: 152, Issue:9

    Topics: Child; Child Nutritional Physiological Phenomena; Cisapride; Esophagitis; Esophagoscopy; Esophagus;

1993
[Cisapride: pharmacology, current therapeutic results and future prospects].
    Gastroenterologie clinique et biologique, 1989, Volume: 13, Issue:3

    Topics: Cisapride; Constipation; Dyspepsia; Esophagitis; Esophagus; Forecasting; Gastric Emptying; Gastroeso

1989

Trials

3 trials available for cisapride and Esophagitis

ArticleYear
Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Enzyme Inhibitors; Esophagitis; Female; Ga

1997
Effect of cisapride on nocturnal transient lower oesophageal sphincter relaxations and nocturnal gastro-oesophageal reflux in patients with oesophagitis: a double-blind, placebo-controlled study.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:4

    Topics: Cisapride; Cross-Over Studies; Double-Blind Method; Esophagitis; Esophagogastric Junction; Female; G

2002
Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:5

    Topics: Adult; Cimetidine; Cisapride; Double-Blind Method; Drug Evaluation; Esophagitis; Esophagoscopy; Fema

1990

Other Studies

6 other studies available for cisapride and Esophagitis

ArticleYear
Frequency, consequences and pharmacological treatment of gastroesophageal reflux in children with cystic fibrosis.
    Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:7

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Child; Child, Preschool; Cisapride; Cystic Fibrosis; Endoscopy

2002
Long-term complications in cases of isolated esophageal atresia treated with esophageal anastomosis.
    Journal of pediatric surgery, 1995, Volume: 30, Issue:8

    Topics: Anastomosis, Surgical; Anti-Ulcer Agents; Cisapride; Constriction, Pathologic; Endoscopy, Digestive

1995
Torticollis as a side effect of cisapride treatment in an infant.
    Journal of pediatric gastroenterology and nutrition, 1996, Volume: 22, Issue:3

    Topics: Cisapride; Esophagitis; Female; Humans; Infant; Piperidines; Torticollis; Trimebutine

1996
[Current indications for cisapride].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8, Issue:4

    Topics: Cisapride; Esophagitis; Gastroesophageal Reflux; Gastrointestinal Agents; Humans

2001
[Cytolytic hepatitis induced by cisapride].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:4

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cisapride; Esophagitis; Humans; Male; Piperidines; Ser

1992
Healing or amelioration of esophagitis does not result in increased lower esophageal sphincter or esophageal contractile pressure.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:10

    Topics: Adult; Aged; Cisapride; Esophageal Motility Disorders; Esophagitis; Esophagogastric Junction; Esopha

1990