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cisapride and Esophageal Dysmotility

cisapride has been researched along with Esophageal Dysmotility in 11 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
" The aim of the study is to compare the clinical efficacy of levosulpiride and cisapride in patients with dysmotility-like functional dyspepsia."9.11Levosulpiride and cisapride in the treatment of dysmotility-like functional dyspepsia: a randomized, double-masked trial. ( Balboa, A; Jiménez, I; Mearin, F; Patón, C; Pérez-Mota, A; Rodrigo, L; Sebastián, JJ, 2004)
" The aim of the study is to compare the clinical efficacy of levosulpiride and cisapride in patients with dysmotility-like functional dyspepsia."5.11Levosulpiride and cisapride in the treatment of dysmotility-like functional dyspepsia: a randomized, double-masked trial. ( Balboa, A; Jiménez, I; Mearin, F; Patón, C; Pérez-Mota, A; Rodrigo, L; Sebastián, JJ, 2004)
"In most patients with progressive systemic sclerosis (PSS) the oesophagus is affected."2.70Effects of cisapride on oesophageal transit of solids in patients with progressive systemic sclerosis. ( Chen, DY; Chen, YH; Hsieh, TY; La, JL; Lin, WY; Wang, SJ, 2002)
"Long-standing gastroesophageal reflux disease (GERD) is frequently associated with impaired esophageal body motility."2.69[Prokinetic medication after surgical therapy of reflux patients with disorders of esophageal peristalsis: a randomized clinical study]. ( Gadenstätter, M; Klocker, J; Weiss, H; Wetscher, GJ, 2000)
"placebo in 12 patients with progressive systemic sclerosis and proven esophageal dysfunction as well as in 10 healthy volunteers in a double-blind, prospective trial."2.67[Effect of cisapride on esophageal motility in healthy probands and patients with progressive systemic scleroderma]. ( Caspary, WF; Wehrmann, T, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (63.64)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mearin, F1
Rodrigo, L1
Pérez-Mota, A1
Balboa, A1
Jiménez, I1
Sebastián, JJ1
Patón, C1
Carella, G1
Marra, L1
Cucchiara, S1
Leelamanit, V1
Geater, A1
Ovartlarnporn, T1
Snape, WJ1
Song, CW1
UM, SH1
Kim, CD1
Ryu, HS1
Hyun, JH1
Choe, JG1
Gadenstätter, M1
Klocker, J1
Weiss, H1
Wetscher, GJ1
Chhina, S1
Peverini, RL1
Deming, DD1
Hopper, AO1
Hashmi, A1
Vyhmeister, NR1
Wang, SJ1
La, JL1
Chen, DY1
Chen, YH1
Hsieh, TY1
Lin, WY1
Wehrmann, T1
Caspary, WF1
Allen, ML1
McIntosh, DL1
Robinson, MG1

Reviews

1 review available for cisapride and Esophageal Dysmotility

ArticleYear
Cisapride therapy for gastrointestinal disease.
    Journal of pediatric gastroenterology and nutrition, 1996, Volume: 22, Issue:3

    Topics: Adult; Animals; Child; Cisapride; Constipation; Esophageal Motility Disorders; Gastrointestinal Dise

1996

Trials

5 trials available for cisapride and Esophageal Dysmotility

ArticleYear
Levosulpiride and cisapride in the treatment of dysmotility-like functional dyspepsia: a randomized, double-masked trial.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2004, Volume: 2, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Cisapride; Dose-Response Relationship, Drug; Double-B

2004
Double-blind placebo-controlled study of cisapride in patients with nonspecific esophageal motility disorder accompanied by delayed esophageal transit.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:6

    Topics: Adult; Cisapride; Double-Blind Method; Esophageal Motility Disorders; Esophagus; Female; Gastrointes

1997
[Prokinetic medication after surgical therapy of reflux patients with disorders of esophageal peristalsis: a randomized clinical study].
    Wiener klinische Wochenschrift, 2000, Nov-10, Volume: 112, Issue:21

    Topics: Adult; Aged; Cisapride; Esophageal Motility Disorders; Female; Follow-Up Studies; Fundoplication; Ga

2000
Effects of cisapride on oesophageal transit of solids in patients with progressive systemic sclerosis.
    Clinical rheumatology, 2002, Volume: 21, Issue:1

    Topics: Administration, Oral; Adult; Aged; Cisapride; Cross-Over Studies; Double-Blind Method; Esophageal Mo

2002
[Effect of cisapride on esophageal motility in healthy probands and patients with progressive systemic scleroderma].
    Klinische Wochenschrift, 1990, Jun-19, Volume: 68, Issue:12

    Topics: Adult; Cisapride; Double-Blind Method; Esophageal Motility Disorders; Esophagus; Female; Humans; Mal

1990

Other Studies

5 other studies available for cisapride and Esophageal Dysmotility

ArticleYear
[Prokinetic drugs in digestive disorders].
    La Clinica terapeutica, 1993, Volume: 143, Issue:3

    Topics: Antineoplastic Agents; Cisapride; Domperidone; Esophageal Motility Disorders; Gastroesophageal Reflu

1993
Cisapride in the treatment of globus hystericus.
    Advances in oto-rhino-laryngology, 1997, Volume: 51

    Topics: Adult; Cisapride; Conversion Disorder; Esophageal Motility Disorders; Esophagogastric Junction; Esop

1997
Managing the patient with atypical chest pain.
    Hospital practice (1995), 1997, Apr-15, Volume: 32, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Algorithms; Amitriptyline; Anti-Ulcer Agents; Atropine; Chest Pain; Ci

1997
QTc interval in infants receiving cisapride.
    Journal of perinatology : official journal of the California Perinatal Association, 2002, Volume: 22, Issue:2

    Topics: Analysis of Variance; Cisapride; Cohort Studies; Dose-Response Relationship, Drug; Drug Administrati

2002
Healing or amelioration of esophagitis does not result in increased lower esophageal sphincter or esophageal contractile pressure.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:10

    Topics: Adult; Aged; Cisapride; Esophageal Motility Disorders; Esophagitis; Esophagogastric Junction; Esopha

1990