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cisapride and Emesis

cisapride has been researched along with Emesis in 18 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
"Although combination antiemetics prevent vomiting during the initial 24 h after high-dose (> or =100 mg/m2) cisplatin, many patients experience delayed emesis 24-120 h afterwards despite receiving prophylactic dexamethasone and metoclopramide during this time."9.09Oral cisapride for the control of delayed vomiting following high-dose cisplatin. ( Baltzer, L; Grant, SC; Hinckley, L; Kris, MG; Miller, VA; Pisters, KM; Pizzo, BA, 1999)
"Cisapride was previously used in the same indication."6.74Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study. ( Advani, N; Alatas, S; Firmansyah, A; Hegar, B; Vandenplas, Y, 2009)
"Cisapride is a strong prokinetic gastrointestinal drug that could have a role in the prevention of DE."6.70Cisapride and dexamethasone in the prevention of delayed emesis after cisplatin administration. ( Caristi, N; Maisano, R; Pergolizzi, S; Salimbeni, V; Spadaro, P; Toscano, G, 2001)
"Treatment with cisapride 10 mg, 4 times daily improved her condition, and this was associated with improved small intestinal motility during a 12-hour examination using a computer aided system."5.28Cisapride stimulates small intestinal motility and relieves constipation in myelopathy due to cervical spinal stenosis: case report. ( Aly, A; Hellström, PM; Johansson, C, 1990)
"Although combination antiemetics prevent vomiting during the initial 24 h after high-dose (> or =100 mg/m2) cisplatin, many patients experience delayed emesis 24-120 h afterwards despite receiving prophylactic dexamethasone and metoclopramide during this time."5.09Oral cisapride for the control of delayed vomiting following high-dose cisplatin. ( Baltzer, L; Grant, SC; Hinckley, L; Kris, MG; Miller, VA; Pisters, KM; Pizzo, BA, 1999)
" We present single-subject trials of two pediatric patients done to assess the effect of cisapride on symptoms arising from gastroesophageal reflux."5.07The single-subject randomized trial. A useful clinical tool for assessing therapeutic efficacy in pediatric practice. ( Issenman, RM; Langer, JC; Winthrop, AL, 1993)
"Cisapride was previously used in the same indication."2.74Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study. ( Advani, N; Alatas, S; Firmansyah, A; Hegar, B; Vandenplas, Y, 2009)
"Cisapride is a strong prokinetic gastrointestinal drug that could have a role in the prevention of DE."2.70Cisapride and dexamethasone in the prevention of delayed emesis after cisplatin administration. ( Caristi, N; Maisano, R; Pergolizzi, S; Salimbeni, V; Spadaro, P; Toscano, G, 2001)
"Recurrent vomiting is one of many functional conditions for which it is difficult to find an explanation and to treat."1.33A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding. ( Ohlsson, B, 2006)
"Vomiting was the first cause of admission in diabetics."1.29Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. ( Gallar, P; Guijo, G; Oliet, A; Ortega, O; Vigil, A, 1993)
"Cisapride was a potent stimulant of gastric emptying in rats, 7 times more potent than metoclopramide."1.28General pharmacology of the four gastrointestinal motility stimulants bethanechol, metoclopramide, trimebutine, and cisapride. ( Awouters, FH; Megens, AA; Niemegeers, CJ, 1991)
"Treatment with cisapride 10 mg, 4 times daily improved her condition, and this was associated with improved small intestinal motility during a 12-hour examination using a computer aided system."1.28Cisapride stimulates small intestinal motility and relieves constipation in myelopathy due to cervical spinal stenosis: case report. ( Aly, A; Hellström, PM; Johansson, C, 1990)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's11 (61.11)18.2507
2000's6 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becker, DP1
Flynn, DL1
Shone, RL1
Gullikson, G1
Hegar, B1
Alatas, S1
Advani, N1
Firmansyah, A1
Vandenplas, Y1
Ohlsson, B1
Washabau, RJ1
Hall, JA1
Carella, G1
Marra, L1
Langer, JC1
Winthrop, AL1
Issenman, RM1
Gallar, P1
Oliet, A1
Vigil, A1
Ortega, O1
Guijo, G1
Sood, AK1
Malhotra, RC1
Sood, S1
Güller, R1
Reichlin, B1
Jost, G1
Pizzo, BA1
Pisters, KM1
Miller, VA1
Grant, SC1
Baltzer, L1
Hinckley, L1
Kris, MG1
Mukhopadhyay, K1
Narang, A1
Kumar, P1
Chakraborty, S1
Mittal, BR1
Maisano, R1
Spadaro, P1
Toscano, G1
Caristi, N1
Pergolizzi, S1
Salimbeni, V1
Shinawi, M1
Brik, R1
Berkowitz, D1
Jenkins, HR1
Verrier-Jones, K1
Megens, AA1
Awouters, FH1
Niemegeers, CJ1
Hellström, PM1
Aly, A1
Johansson, C1
McCallum, RW1

Reviews

1 review available for cisapride and Emesis

ArticleYear
Cisapride.
    Journal of the American Veterinary Medical Association, 1995, Nov-15, Volume: 207, Issue:10

    Topics: Animals; Cisapride; Esophagus; Gastric Emptying; Gastroesophageal Reflux; Gastrointestinal Motility;

1995

Trials

5 trials available for cisapride and Emesis

ArticleYear
Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:4

    Topics: Antiemetics; Cardiovascular System; Cisapride; Domperidone; Electrocardiography; Esophageal pH Monit

2009
The single-subject randomized trial. A useful clinical tool for assessing therapeutic efficacy in pediatric practice.
    Clinical pediatrics, 1993, Volume: 32, Issue:11

    Topics: Adult; Child; Child, Preschool; Cisapride; Gagging; Gastroesophageal Reflux; Humans; Infant; Male; P

1993
[Colonic preparation with sodium phosphate. Prospective, randomized, placebo-controlled double blind study with various antiemetics].
    Schweizerische medizinische Wochenschrift, 1996, Aug-06, Volume: 126, Issue:31-32

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Cathartics; Cisapride

1996
Oral cisapride for the control of delayed vomiting following high-dose cisplatin.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Aged; Antiemetics; Antineoplastic Agents; Cisapride; Cisplatin

1999
Cisapride and dexamethasone in the prevention of delayed emesis after cisplatin administration.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2001, Volume: 9, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Agents; Cisapride; Cisplatin; Dexamet

2001

Other Studies

12 other studies available for cisapride and Emesis

ArticleYear
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.
    Bioorganic & medicinal chemistry letters, 2004, Nov-15, Volume: 14, Issue:22

    Topics: Adamantane; Animals; Aza Compounds; Benzamides; Cisplatin; Dogs; Gastrointestinal Agents; Gastrointe

2004
[With evidence-based phytotherapy. Takes away gastric and intestinal irritation].
    MMW Fortschritte der Medizin, 2003, Mar-27, Volume: 145, Issue:13

    Topics: Antiemetics; Cisapride; Clinical Trials as Topic; Dopamine Antagonists; Evidence-Based Medicine; Gas

2003
A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding.
    BMC gastroenterology, 2006, Oct-21, Volume: 6

    Topics: Acetylcholine; Adult; Breast Feeding; Cisapride; Endoscopy, Digestive System; Female; Gastric Emptyi

2006
[Prokinetic drugs in digestive disorders].
    La Clinica terapeutica, 1993, Volume: 143, Issue:3

    Topics: Antineoplastic Agents; Cisapride; Domperidone; Esophageal Motility Disorders; Gastroesophageal Reflu

1993
Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1993, Volume: 13 Suppl 2

    Topics: Cisapride; Diabetes Mellitus, Type 1; Erythromycin; Female; Gastric Emptying; Hospitalization; Human

1993
Rumination-treatment with cisapride.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Cisapride; Female; Gastroesophageal Reflux; Humans; Male; Parasympatholytics; Pip

1995
Gastroesophageal reflux and pulmonary complication in a neonate.
    Indian pediatrics, 1998, Volume: 35, Issue:7

    Topics: Antiemetics; Apnea; Cisapride; Follow-Up Studies; Gastroesophageal Reflux; Gastrointestinal Agents;

1998
Gastrointestinal tract cytomegalovirus infection with prolonged vomiting and fever in an immunocompetent child.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:8

    Topics: Cisapride; Cytomegalovirus; Cytomegalovirus Infections; Fever; Gastrointestinal Agents; Gastrointest

2001
Vomiting and chronic renal failure.
    Pediatric nephrology (Berlin, Germany), 1991, Volume: 5, Issue:4

    Topics: Administration, Oral; Cisapride; Gastroesophageal Reflux; Humans; Infant; Kidney Failure, Chronic; P

1991
General pharmacology of the four gastrointestinal motility stimulants bethanechol, metoclopramide, trimebutine, and cisapride.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:6

    Topics: Animals; Apomorphine; Bethanechol Compounds; Cisapride; Conditioning, Operant; Diarrhea; Dogs; Gastr

1991
Cisapride stimulates small intestinal motility and relieves constipation in myelopathy due to cervical spinal stenosis: case report.
    Paraplegia, 1990, Volume: 28, Issue:4

    Topics: Cisapride; Constipation; Female; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Intest

1990
Review of the current status of prokinetic agents in gastroenterology.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:12

    Topics: Benzamides; Chemical Phenomena; Chemistry; Cisapride; Dexamethasone; Digestive System; Domperidone;

1985