Page last updated: 2024-10-25

cisapride and Dysphagia

cisapride has been researched along with Dysphagia in 9 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
" This hypothesis was tested in a small pilot study treating functional dysphagia with cisapride."3.68Oesophageal reflex responses: abnormalities of the enteric nervous system in patients with oesophageal symptoms. ( Bancewicz, J; Marples, M; O'Hanrahan, T; Thompson, D; Williams, D, 1992)
"Only surgery improved regurgitation."1.30The effect of medical therapy and antireflux surgery on dysphagia in patients with gastroesophageal reflux disease without esophageal stricture. ( Gadenstaetter, M; Glaser, K; Hinder, RA; Profanter, C; Wetscher, GJ, 1999)
"Eighty GERD patients with either dysphagia or respiratory symptoms were studied by means of a detailed symptom questionnaire, upper gastrointestinal endoscopy, esophageal manometry, 24-h esophageal pH monitoring and a barium esophagogram."1.30Respiratory symptoms and dysphagia in patients with gastroesophageal reflux disease: a comparison of medical and surgical therapy. ( Gadenstätter, M; Profanter, C; Schwab, GP; Wetscher, GJ; Wykypiel, H, 1999)
"Esophageal leiomyomatosis is triggered by diffuse proliferation of smooth muscle cells in the wall of the entire esophagus."1.29[Leiomyomatosis of the esophagus]. ( Grönniger, J; Hillemanns, A; Oglodek, C; Reinbold, WD, 1994)
"No episode of probable/possible aspiration pneumonia was observed during the follow-up."1.29Prevention of aspiration pneumonia during long-term feeding by percutaneous endoscopic gastrostomy: might cisapride play any role? An open pilot study. ( Donati, D; Gilli, G; Malacarne, P; Nielsen, I; Sartori, S; Tassinari, D; Trevisani, L, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (88.89)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reinbold, WD1
Oglodek, C1
Hillemanns, A1
Grönniger, J1
Sartori, S1
Trevisani, L1
Tassinari, D1
Nielsen, I1
Gilli, G1
Donati, D1
Malacarne, P1
Sharman, JM1
McDougall, NI1
Johnston, BT1
Kee, F1
Collins, JS1
McFarland, RJ1
Love, AH1
Inder, TE1
Volpe, JJ1
Wetscher, GJ2
Glaser, K1
Gadenstaetter, M1
Profanter, C2
Hinder, RA1
Gadenstätter, M1
Wykypiel, H1
Schwab, GP1
Chattopadhyay, A1
Singh, S1
Sood, A1
Wanchu, A1
Bambery, P1
O'Hanrahan, T1
Bancewicz, J1
Thompson, D1
Marples, M1
Williams, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404]98 participants (Actual)Interventional2009-03-01Completed
Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study[NCT01574573]52 participants (Actual)Interventional2009-06-30Terminated (stopped due to Closed due to lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cisapride and Dysphagia

ArticleYear
Recovery of congenital isolated pharyngeal dysfunction: implications for early management.
    Pediatric neurology, 1998, Volume: 19, Issue:3

    Topics: Cisapride; Deglutition Disorders; Electromyography; Female; Humans; Infant, Newborn; Neurologic Exam

1998

Other Studies

8 other studies available for cisapride and Dysphagia

ArticleYear
[Leiomyomatosis of the esophagus].
    Der Radiologe, 1994, Volume: 34, Issue:9

    Topics: Anti-Ulcer Agents; Biopsy; Cisapride; Combined Modality Therapy; Deglutition Disorders; Esophageal N

1994
Prevention of aspiration pneumonia during long-term feeding by percutaneous endoscopic gastrostomy: might cisapride play any role? An open pilot study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1994, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cisapride; Deglutition Disorders; Enteral Nutrition; Fem

1994
Cisapride to relieve dysphagia.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 1993, Volume: 43, Issue:377

    Topics: Aged; Aged, 80 and over; Cisapride; Deglutition Disorders; Humans; Male; Piperidines; Serotonin Anta

1993
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
The effect of medical therapy and antireflux surgery on dysphagia in patients with gastroesophageal reflux disease without esophageal stricture.
    American journal of surgery, 1999, Volume: 177, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Cisapride;

1999
Respiratory symptoms and dysphagia in patients with gastroesophageal reflux disease: a comparison of medical and surgical therapy.
    Langenbeck's archives of surgery, 1999, Volume: 384, Issue:6

    Topics: Cisapride; Deglutition Disorders; Female; Fundoplication; Gastroesophageal Reflux; Gastrointestinal

1999
Cervical osteophyte induced dysphagia.
    The Journal of the Association of Physicians of India, 2001, Volume: 49

    Topics: Anti-Ulcer Agents; Cervical Vertebrae; Cisapride; Deglutition Disorders; Esophageal Stenosis; Gastro

2001
Oesophageal reflex responses: abnormalities of the enteric nervous system in patients with oesophageal symptoms.
    The British journal of surgery, 1992, Volume: 79, Issue:9

    Topics: Adult; Aged; Catheterization; Cisapride; Deglutition Disorders; Esophageal Diseases; Esophagus; Fema

1992