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cisapride and Duodenal Reflux

cisapride has been researched along with Duodenal Reflux in 7 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to look at duodenal reflux in the oesophagus together with motility characteristics in a group of patients with Barrett's oesophagus and compare them with a mild oesophagitis group and to assess the effect of cisapride on any abnormalities."9.08Effect of cisapride on oesophageal motility and duodenogastro-oesophageal reflux in patients with Barrett's oesophagus. ( Bird, NC; Globe, J; Johnson, AG; Smythe, A; Troy, GP, 1997)
"The aim of this work was to assess the effect of 10 mg of cisapride twice daily for 1 week on symptoms, gastroduodenal reflux and gall bladder emptying in patients undergoing cholecystectomy."9.08Effect of cisapride on gastroduodenal reflux and gall bladder motility in patients with gallstones. ( Baxter, PS; Maddern, GJ, 1998)
" It was the aim of this study to assess the acute effects of cisapride on antroduodenal motility and duodenogastric reflux in seven patients with severe dyspepsia and increased biliary reflux, as evidenced by increased bile salt output in their gastric aspirates."9.06Cisapride stimulates antral motility and decreases biliary reflux in patients with severe dyspepsia. ( Di Lorenzo, C; Dooley, CP; Rezende-Filho, J; Valenzuela, JE, 1989)
"Medical treatment of duodenogastroesophageal reflux in postgastrectomy patients has been disappointing."6.68Placebo-controlled trial of cisapride in postgastrectomy patients with duodenogastroesophageal reflux. ( Richter, JE; Sears, R; Vaezi, MF, 1996)
" The aim of this study was to look at duodenal reflux in the oesophagus together with motility characteristics in a group of patients with Barrett's oesophagus and compare them with a mild oesophagitis group and to assess the effect of cisapride on any abnormalities."5.08Effect of cisapride on oesophageal motility and duodenogastro-oesophageal reflux in patients with Barrett's oesophagus. ( Bird, NC; Globe, J; Johnson, AG; Smythe, A; Troy, GP, 1997)
" It was the aim of this study to assess the acute effects of cisapride on antroduodenal motility and duodenogastric reflux in seven patients with severe dyspepsia and increased biliary reflux, as evidenced by increased bile salt output in their gastric aspirates."5.06Cisapride stimulates antral motility and decreases biliary reflux in patients with severe dyspepsia. ( Di Lorenzo, C; Dooley, CP; Rezende-Filho, J; Valenzuela, JE, 1989)
"To confirm the diagnosis of duodenogastric reflux, cholescintigraphy (Tc99-HEPIDA) was performed."2.69Duodenogastric reflux: clinical and therapeutic aspects. ( KamiƱska, B; Korzon, M; Lass, P; Szarszewski, A, 1999)
"Medical treatment of duodenogastroesophageal reflux in postgastrectomy patients has been disappointing."2.68Placebo-controlled trial of cisapride in postgastrectomy patients with duodenogastroesophageal reflux. ( Richter, JE; Sears, R; Vaezi, MF, 1996)
"Primary duodenogastric reflux is a rare disorder in adults which has not yet been documented in children."1.32Primary duodenogastric reflux in children and adolescents. ( Buts, JP; Collard, JM; Hermans, D; Romagnoli, R; Sokal, EM, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smythe, A2
Bird, NC2
Troy, GP2
Ackroyd, R1
Johnson, AG2
Hermans, D1
Sokal, EM1
Collard, JM1
Romagnoli, R1
Buts, JP1
Vaezi, MF1
Sears, R1
Richter, JE1
Globe, J1
Baxter, PS1
Maddern, GJ1
Szarszewski, A1
Korzon, M1
KamiƱska, B1
Lass, P1
Rezende-Filho, J1
Di Lorenzo, C1
Dooley, CP1
Valenzuela, JE1

Trials

6 trials available for cisapride and Duodenal Reflux

ArticleYear
Does the addition of a prokinetic to proton pump inhibitor therapy help reduce duodenogastro-oesophageal reflux in patients with Barrett's oesophagus?
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:3

    Topics: Adult; Aged; Anti-Ulcer Agents; Barrett Esophagus; Cisapride; Double-Blind Method; Drug Therapy, Com

2003
Placebo-controlled trial of cisapride in postgastrectomy patients with duodenogastroesophageal reflux.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:4

    Topics: Anti-Ulcer Agents; Bilirubin; Cisapride; Cross-Over Studies; Double-Blind Method; Duodenogastric Ref

1996
Effect of cisapride on oesophageal motility and duodenogastro-oesophageal reflux in patients with Barrett's oesophagus.
    European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:12

    Topics: Adult; Aged; Barrett Esophagus; Bile Acids and Salts; Cisapride; Duodenogastric Reflux; Electrodes;

1997
Effect of cisapride on gastroduodenal reflux and gall bladder motility in patients with gallstones.
    Digestive surgery, 1998, Volume: 15, Issue:1

    Topics: Adult; Aged; Cholecystectomy; Cisapride; Double-Blind Method; Duodenogastric Reflux; Female; Gallbla

1998
Duodenogastric reflux: clinical and therapeutic aspects.
    Archives of disease in childhood, 1999, Volume: 81, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Cisapride; Duodenogastric Reflux; Endoscopy, Gastrointestinal;

1999
Cisapride stimulates antral motility and decreases biliary reflux in patients with severe dyspepsia.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:7

    Topics: Adult; Aged; Bile Acids and Salts; Cisapride; Double-Blind Method; Duodenogastric Reflux; Dyspepsia;

1989

Other Studies

1 other study available for cisapride and Duodenal Reflux

ArticleYear
Primary duodenogastric reflux in children and adolescents.
    European journal of pediatrics, 2003, Volume: 162, Issue:9

    Topics: Adolescent; Anti-Ulcer Agents; Belgium; Bile Reflux; Chelating Agents; Child; Child Welfare; Child,

2003