cisapride has been researched along with Drop Attack in 7 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adverse cardiac events, typically long QT syndrome, have been reported in patients treated with the gastrointestinal prokinetic agent cisapride." | 8.81 | Spontaneous adverse event reports of serious ventricular arrhythmias, QT prolongation, syncope, and sudden death in patients treated with cisapride. ( Barbey, JT; Lazzara, R; Zipes, DP, 2002) |
| " Linkage to cisapride was probable, promoted by high dosage and cisapride metabolism inhibition by ranitidine, but its plasma concentration was not measured." | 5.30 | [Syncope with long QT interval in a 39 day-old infant treated with cisapride]. ( Autret, E; Champel, V; Jonville-Bera, AP; Olivier, C; Valdes, L, 1997) |
| "Adverse cardiac events, typically long QT syndrome, have been reported in patients treated with the gastrointestinal prokinetic agent cisapride." | 4.81 | Spontaneous adverse event reports of serious ventricular arrhythmias, QT prolongation, syncope, and sudden death in patients treated with cisapride. ( Barbey, JT; Lazzara, R; Zipes, DP, 2002) |
| " Continuous 24-h ECG recording detected a ventricular tachycardia in torsades de pointes inducing a syncopal convulsive attack that seemed to be related to oral Cisapride assumption for dyspepsia." | 3.74 | An anorexic woman with convulsive loss of consciousness. Syncope or epileptic fits? ( Argiriadou, V; Attanasio, A; Diomedi, M; Sandri, G, 2007) |
| "One patient died from ventricular arrhythmia 12 days after discontinuing cisapride." | 1.31 | Retrospective analysis of cisapride-induced QT changes in end-stage renal disease patients. ( Gunderson, BW; Hentges, MJ; Lewis, MJ, 2000) |
| " Linkage to cisapride was probable, promoted by high dosage and cisapride metabolism inhibition by ranitidine, but its plasma concentration was not measured." | 1.30 | [Syncope with long QT interval in a 39 day-old infant treated with cisapride]. ( Autret, E; Champel, V; Jonville-Bera, AP; Olivier, C; Valdes, L, 1997) |
| "To report a case of QT prolongation and syncopal episodes resulting from concomitant use of cisapride and agents known to inhibit its metabolism." | 1.30 | Syncopal episodes associated with cisapride and concurrent drugs. ( Gray, VS, 1998) |
| "Respiratory complications of gastroesophageal reflux disease that have been reported include hoarseness, wheezing, bronchospasm, stridor, laryngitis, and chronic cough." | 1.29 | Gastroesophageal reflux-induced cough syncope. ( Puetz, TR; Vakil, N, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Attanasio, A | 1 |
| Argiriadou, V | 1 |
| Sandri, G | 1 |
| Diomedi, M | 1 |
| Puetz, TR | 1 |
| Vakil, N | 1 |
| Valdes, L | 1 |
| Champel, V | 1 |
| Olivier, C | 1 |
| Jonville-Bera, AP | 1 |
| Autret, E | 1 |
| Gray, VS | 1 |
| Trinkle, R | 1 |
| Hentges, MJ | 1 |
| Gunderson, BW | 1 |
| Lewis, MJ | 1 |
| Barbey, JT | 1 |
| Lazzara, R | 1 |
| Zipes, DP | 1 |
1 review available for cisapride and Drop Attack
| Article | Year |
|---|---|
Spontaneous adverse event reports of serious ventricular arrhythmias, QT prolongation, syncope, and sudden death in patients treated with cisapride.
Topics: Arrhythmias, Cardiac; Cisapride; Death, Sudden, Cardiac; Gastrointestinal Agents; Humans; Long QT Sy | 2002 |
6 other studies available for cisapride and Drop Attack
| Article | Year |
|---|---|
An anorexic woman with convulsive loss of consciousness. Syncope or epileptic fits?
Topics: Adult; Anorexia; Cisapride; Diagnosis, Differential; Dyspepsia; Epilepsy; Female; Gastrointestinal A | 2007 |
Gastroesophageal reflux-induced cough syncope.
Topics: Adult; Cisapride; Cough; Drug Therapy, Combination; Gastroesophageal Reflux; Humans; Male; Monitorin | 1995 |
[Syncope with long QT interval in a 39 day-old infant treated with cisapride].
Topics: Anti-Ulcer Agents; Cisapride; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gastroeso | 1997 |
Syncopal episodes associated with cisapride and concurrent drugs.
Topics: Accidents, Traffic; Anti-Bacterial Agents; Anti-Ulcer Agents; Cisapride; Clarithromycin; Cytochrome | 1998 |
Comment: syncopal episodes associated with cisapride.
Topics: Cisapride; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Gastrointestinal Ag | 1999 |
Retrospective analysis of cisapride-induced QT changes in end-stage renal disease patients.
Topics: Arrhythmias, Cardiac; Cisapride; Diabetic Nephropathies; Electrocardiography; Ethnicity; Female; Gas | 2000 |