cisapride has been researched along with Diarrhea in 8 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A controlled multi-centre clinical trial was conducted for evaluating the efficacy and safety of cisapride in the treatment of 414 cases of functional dyspepsia with 169 cases as control." | 9.08 | [A controlled multi-centre clinical trial on cisapride in treatment of functional dyspepsia]. ( Jia, B; Liang, X; Wang, B, 1995) |
| "Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown." | 6.68 | The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997) |
| "A controlled multi-centre clinical trial was conducted for evaluating the efficacy and safety of cisapride in the treatment of 414 cases of functional dyspepsia with 169 cases as control." | 5.08 | [A controlled multi-centre clinical trial on cisapride in treatment of functional dyspepsia]. ( Jia, B; Liang, X; Wang, B, 1995) |
| "Cisapride has been reported to improve symptoms in patients with constipation-predominant irritable bowel syndrome." | 5.08 | Effects of oral cisapride on small bowel motility in irritable bowel syndrome. ( Bak, YT; Evans, PR; Kellow, JE, 1997) |
| "Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown." | 2.68 | The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997) |
| "Cisapride was a potent stimulant of gastric emptying in rats, 7 times more potent than metoclopramide." | 1.28 | General pharmacology of the four gastrointestinal motility stimulants bethanechol, metoclopramide, trimebutine, and cisapride. ( Awouters, FH; Megens, AA; Niemegeers, CJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, B | 1 |
| Liang, X | 1 |
| Jia, B | 1 |
| Evans, PR | 1 |
| Bak, YT | 1 |
| Kellow, JE | 1 |
| Hatlebakk, JG | 1 |
| Johnsson, F | 1 |
| Vilien, M | 1 |
| Carling, L | 1 |
| Wetterhus, S | 1 |
| Thøgersen, T | 1 |
| Fernández-Fernández, FJ | 1 |
| González-González, C | 1 |
| Castro-Alvariño, J | 1 |
| Sesma, P | 1 |
| Sanger, GJ | 1 |
| Megens, AA | 1 |
| Awouters, FH | 1 |
| Niemegeers, CJ | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Campbell, FC | 1 |
| Storey, BE | 1 |
| Cullen, PT | 1 |
| Cuschieri, A | 1 |
1 review available for cisapride and Diarrhea
| Article | Year |
|---|---|
Hypersensitivity and hyperreactivity in the irritable bowel syndrome: An opportunity for drug discovery.
Topics: Abdominal Pain; Afferent Pathways; Animals; Cisapride; Colonic Diseases, Functional; Constipation; D | 1999 |
3 trials available for cisapride and Diarrhea
| Article | Year |
|---|---|
[A controlled multi-centre clinical trial on cisapride in treatment of functional dyspepsia].
Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Diarrhea; Dyspepsia; Female; Humans; Male; Middl | 1995 |
Effects of oral cisapride on small bowel motility in irritable bowel syndrome.
Topics: Adult; Cisapride; Colonic Diseases, Functional; Constipation; Diarrhea; Eating; Female; Gastrointest | 1997 |
The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease.
Topics: Abdominal Pain; Cisapride; Constipation; Diarrhea; Drug Administration Schedule; Endoscopy; Esophagi | 1997 |
4 other studies available for cisapride and Diarrhea
| Article | Year |
|---|---|
[Cisapride in idiopathic megacolon-megarectum].
Topics: Adolescent; Chronic Disease; Cisapride; Combined Modality Therapy; Diarrhea; Dilatation, Pathologic; | 1999 |
General pharmacology of the four gastrointestinal motility stimulants bethanechol, metoclopramide, trimebutine, and cisapride.
Topics: Animals; Apomorphine; Bethanechol Compounds; Cisapride; Conditioning, Operant; Diarrhea; Dogs; Gastr | 1991 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Surface vibration analysis (SVA): a new non-invasive monitor of gastrointestinal activity.
Topics: Adult; Cisapride; Diarrhea; Digestive System; Digestive System Physiological Phenomena; Gastrointest | 1989 |