cisapride has been researched along with Diabetes Mellitus in 5 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conclude that long-term administration of cisapride reduced dysmotility symptoms and improved solid and liquid gastric emptying without adversely affecting glycemic control." | 5.29 | [Influence on glycemic control of improved diabetic gastroparesis by long-term cisapride therapy]. ( Ishii, K; Mitsuhashi, T; Saigenji, K; Tanabe, S, 1995) |
| "Cisapride is a prokinetic agent believed to facilitate acetylcholine release from the myenteric plexus of the gut." | 2.66 | Effect of cisapride on gastric emptying of indigestible solids in patients with gastroparesis diabeticorum. A comparison with metoclopramide and placebo. ( Feldman, M; Smith, HJ, 1987) |
| " We conclude that long-term administration of cisapride reduced dysmotility symptoms and improved solid and liquid gastric emptying without adversely affecting glycemic control." | 1.29 | [Influence on glycemic control of improved diabetic gastroparesis by long-term cisapride therapy]. ( Ishii, K; Mitsuhashi, T; Saigenji, K; Tanabe, S, 1995) |
| "Delayed gastric emptying is supposed to affect glycemic control in diabetic patients by relative over dosing of insulin to blood glucose level due to delayed absorption of nutrients." | 1.27 | [Effect of cisapride on delayed gastric emptying in diabetic patients]. ( Goto, Y; Hongo, M; Lin, YF; Okuyama, S; Satake, K; Toyota, T; Ujiie, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, K | 1 |
| Tanabe, S | 1 |
| Mitsuhashi, T | 1 |
| Saigenji, K | 1 |
| Horowitz, M | 1 |
| O'Donovan, D | 1 |
| Jones, KL | 1 |
| Feinle, C | 1 |
| Rayner, CK | 1 |
| Samsom, M | 1 |
| Kawagishi, T | 1 |
| Nishizawa, Y | 1 |
| Okuno, Y | 1 |
| Sekiya, K | 1 |
| Morii, H | 1 |
| Lin, YF | 1 |
| Hongo, M | 1 |
| Satake, K | 1 |
| Ujiie, H | 1 |
| Toyota, T | 1 |
| Goto, Y | 1 |
| Okuyama, S | 1 |
| Feldman, M | 1 |
| Smith, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Preoperative Oral Carbohydrate on Recovery in Diabetic Patients After Gastrointestinal Surgery: a Pilot Randomized Controlled Trial[NCT03204344] | 65 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cisapride and Diabetes Mellitus
| Article | Year |
|---|---|
Gastric emptying in diabetes: clinical significance and treatment.
Topics: Blood Glucose; Cisapride; Diabetes Mellitus; Diabetic Neuropathies; Domperidone; Gastric Emptying; G | 2002 |
1 trial available for cisapride and Diabetes Mellitus
| Article | Year |
|---|---|
Effect of cisapride on gastric emptying of indigestible solids in patients with gastroparesis diabeticorum. A comparison with metoclopramide and placebo.
Topics: Adult; Cisapride; Diabetes Mellitus; Double-Blind Method; Female; Gastric Emptying; Humans; Male; Me | 1987 |
3 other studies available for cisapride and Diabetes Mellitus
| Article | Year |
|---|---|
[Influence on glycemic control of improved diabetic gastroparesis by long-term cisapride therapy].
Topics: Adult; Aged; Blood Glucose; Cisapride; Diabetes Complications; Diabetes Mellitus; Female; Gastric Em | 1995 |
Segmental gut transit in diabetes mellitus: effect of cisapride.
Topics: Administration, Oral; Adult; Cisapride; Colon; Contrast Media; Diabetes Mellitus; Diabetic Nephropat | 1992 |
[Effect of cisapride on delayed gastric emptying in diabetic patients].
Topics: Administration, Oral; Blood Glucose; Cisapride; Diabetes Mellitus; Female; Gastric Emptying; Humans; | 1988 |