cisapride has been researched along with Diabetes Mellitus, Type 2 in 7 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In conclusion, this study showed that cisapride can improve gastric dysrhythmia during both fasting and post-meal phases in patients with diabetic gastroparesis." | 5.08 | Effect of cisapride on gastric dysrhythmia and emptying of indigestible solids in type-II diabetic patients. ( Chang, CS; Chen, GH; Lien, HC; Poon, SK; Tung, CF; Yeh, HZ, 1998) |
| "Cisapride is a prokinetic drug of the gastrointestinal tract and acts by releasing acetylcholine from cholinergic nerve endings." | 1.31 | Cisapride improves gallbladder emptying in patients with type 2 diabetes mellitus. ( Arke, L; Bhansali, A; Chawla, YK; Dhiman, RK; Gupta, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssen, P | 1 |
| Harris, MS | 1 |
| Jones, M | 1 |
| Masaoka, T | 1 |
| Farré, R | 1 |
| Törnblom, H | 1 |
| Van Oudenhove, L | 1 |
| Simrén, M | 1 |
| Tack, J | 1 |
| Kawagishi, T | 1 |
| Nishizawa, Y | 1 |
| Okuno, Y | 1 |
| Sekiya, K | 1 |
| Morii, H | 1 |
| Allegra, G | 1 |
| Costa, R | 1 |
| Scaffidi, L | 1 |
| Campisi, D | 1 |
| Cangialosi, G | 1 |
| Scaffidi, A | 1 |
| Chang, CS | 1 |
| Lien, HC | 1 |
| Yeh, HZ | 1 |
| Poon, SK | 1 |
| Tung, CF | 1 |
| Chen, GH | 1 |
| SoRelle, R | 1 |
| Dhiman, RK | 1 |
| Arke, L | 1 |
| Bhansali, A | 1 |
| Gupta, S | 1 |
| Chawla, YK | 1 |
| Kasai, S | 1 |
| Tanaka, K | 1 |
| Machimura, H | 1 |
| Takeda, H | 1 |
| Kaneshige, H | 1 |
| Sakai, H | 1 |
| Harasawa, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cisapride and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis.
Topics: Cisapride; Diabetes Mellitus, Type 2; Domperidone; Erythromycin; Gastric Emptying; Gastrointestinal | 2013 |
2 trials available for cisapride and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Effect of cisapride on gastric emptying of indigestible solids and plasma motilin concentration in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Cisapride; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1993 |
Effect of cisapride on gastric dysrhythmia and emptying of indigestible solids in type-II diabetic patients.
Topics: Blood Glucose; Cisapride; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Gastrointestinal Agen | 1998 |
4 other studies available for cisapride and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
[The evaluation of the time of gastric radio-isotopic emptying in subjects with non-insulin dependent diabetes mellitus].
Topics: Aged; Cisapride; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Humans; Male; Middle Aged; Pip | 1996 |
Drugs and disease.
Topics: Chromans; Cisapride; Diabetes Mellitus, Type 2; Drug and Narcotic Control; Gastroesophageal Reflux; | 2000 |
Cisapride improves gallbladder emptying in patients with type 2 diabetes mellitus.
Topics: Acetylcholine; Administration, Oral; Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Cis | 2001 |
Effect of cisapride on gastric emptying in diabetic patients without gastrointestinal symptoms.
Topics: Acetaminophen; Blood Glucose; Cisapride; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucos | 1991 |