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cisapride and Cushing's Syndrome

cisapride has been researched along with Cushing's Syndrome in 5 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
"The serotonin4 (5-HT4) receptor agonists cisapride and/or metoclopramide have been shown to stimulate cortisol secretion in some patients with ACTH-independent bilateral macronodular adrenal hyperplasias (AIMAH) causing Cushing's syndrome."7.72Overexpression of serotonin4 receptors in cisapride-responsive adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia causing Cushing's syndrome. ( Bastard, C; Bertherat, J; Caron, P; Cartier, D; Kuhn, JM; Lacroix, A; Lefebvre, H; Lihrmann, I; Parmentier, F; Tabarin, A; Vaudry, H; Young, J, 2003)
"The serotonin4 (5-HT4) receptor agonists cisapride and/or metoclopramide have been shown to stimulate cortisol secretion in some patients with ACTH-independent bilateral macronodular adrenal hyperplasias (AIMAH) causing Cushing's syndrome."3.72Overexpression of serotonin4 receptors in cisapride-responsive adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia causing Cushing's syndrome. ( Bastard, C; Bertherat, J; Caron, P; Cartier, D; Kuhn, JM; Lacroix, A; Lefebvre, H; Lihrmann, I; Parmentier, F; Tabarin, A; Vaudry, H; Young, J, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cartier, D1
Lihrmann, I1
Parmentier, F1
Bastard, C1
Bertherat, J2
Caron, P1
Kuhn, JM3
Lacroix, A2
Tabarin, A1
Young, J1
Vaudry, H3
Lefebvre, H3
Contesse, V2
Reznik, Y1
Duparc, C2
Perraudin, V1
Mannelli, M1
Ferruzzi, P1
Luciani, P1
Crescioli, C1
Buci, L1
Corona, G1
Serio, M1
Peri, A1
Louiset, E1
Barrande, G1
Groussin, L1
Emy, P1
Bertagna, X1
Bourdeau, I1
D'Amour, P1
Hamet, P1
Boutin, JM1

Trials

1 trial available for cisapride and Cushing's Syndrome

ArticleYear
Aberrant membrane hormone receptors in incidentally discovered bilateral macronodular adrenal hyperplasia with subclinical Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:11

    Topics: Adrenal Hyperplasia, Congenital; Cisapride; Cushing Syndrome; Dopamine Antagonists; Female; Follicle

2001

Other Studies

4 other studies available for cisapride and Cushing's Syndrome

ArticleYear
Overexpression of serotonin4 receptors in cisapride-responsive adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia causing Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Cisapride; Cushing

2003
Effects of serotonin and vasopressin on cortisol production from an adrenocortical tumor causing subclinical Cushing's syndrome.
    Endocrine research, 2002, Volume: 28, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Arginine Vasopressin; Cisapride; Culture Techniques; Cushing Synd

2002
Cushing's syndrome in a patient with bilateral macronodular adrenal hyperplasia responding to cisapride: an in vivo and in vitro study.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:10

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cisapride; Cushing Syndrome; Female; Gene Expression; H

2003
In vivo and in vitro screening for illegitimate receptors in adrenocorticotropin-independent macronodular adrenal hyperplasia causing Cushing's syndrome: identification of two cases of gonadotropin/gastric inhibitory polypeptide-dependent hypercortisolism
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Cells, Cultured; Chorionic

2005