cisapride has been researched along with Constipation in 78 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies with cisapride reported conflicting results in patients with constipation-predominant irritable bowel syndrome (IBS)." | 9.11 | Cisapride treatment of constipation-predominant irritable bowel syndrome is not superior to placebo. ( Kruis, W; Ziegenhagen, DJ, 2004) |
| "The effects of cisapride (10 mg three times daily) on the stool evacuation characteristics, laxative consumption (symptom diary) and motility pattern (rectoanal manometry) were assessed in patients with chronic idiopathic constipation who fulfilled Rome II criteria." | 9.10 | The efficacy of cisapride vs. placebo and diet in patients with chronic constipation. ( Altabas, K; Bilić, A; Dorosulić, Z; Jurcić, D; Mihanović, M; Restek-Petrović, B; Sunić-Omejc, M; Tolj, N, 2003) |
| "Cisapride was effective in the treatment of children with constipation." | 9.09 | Cisapride for the treatment of constipation in children: A double-blind study. ( Garcia-Aranda, JA; Nurko, S; Worona, LB; Zlochisty, O, 2000) |
| "Cisapride may have a role in the management of chronic idiopathic constipation in children." | 9.09 | Cisapride in management of chronic pediatric constipation. ( Halabi, IM, 1999) |
| "These results indicate that cisapride is not superior to placebo in the treatment of constipation and abdominal discomfort as components of irritable bowel syndrome." | 9.08 | Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome. ( Brandstätter, G; Dragosics, B; Hentschel, E; Judmaier, G; Schütze, K, 1997) |
| "To establish whether cisapride is beneficial in children with intractable constipation, an open trial was performed." | 9.08 | Treatment of intractable constipation in children: experience with cisapride. ( Garcia-Aranda, JA; Guerrero, VY; Nurko, S; Worona, LB, 1996) |
| "This study did not demonstrate a clinical role for the use of cisapride in the treatment of idiopathic constipation in children." | 9.08 | Use of cisapride in treatment of constipation in children. ( Doig, C; Miller, V; Odeka, EB; Sagher, F, 1997) |
| "This study confirmed the efficacy of cisapride in chronic idiopathic constipation." | 9.08 | Cisapride in chronic idiopathic constipation: can the colon be re-educated? Bavarian Constipation Study Group. ( Müller-Lissner, SA, 1995) |
| "Cisapride improves symptoms in patients with idiopathic constipation." | 9.08 | The symptomatic effect of cisapride in patients with irritable bowel syndrome and constipation. ( Farup, PG; Hovde, O; Hovdenak, N; Lange, OJ; Trondstad, R; Wetterhus, S, 1998) |
| "The efficacy of cisapride as a treatment for chronic constipation in children with severe brain damage was studied in 20 children." | 9.08 | Cisapride in neurologically impaired children with chronic constipation. ( Del Giudice, E; Marino, A; Miele, E; Simeone, D; Staiano, A, 1996) |
| "The efficacy of cisapride, a new prokinetic drug, as a treatment for chronic functional constipation of childhood was studied in 20 constipated children." | 9.07 | Effect of cisapride on chronic idiopathic constipation in children. ( Andreotti, MR; Cucchiara, S; Manzi, G; Minella, R; Staiano, A, 1991) |
| "The effects of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome (IBS) were evaluated in a randomized, double-blind, placebo-controlled study." | 9.07 | "Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride. ( Milo, R; Toussaint, J; Van Eeghem, P; Van Outryve, M, 1991) |
| "The effect of cisapride (20 mg bid), a new prokinetic drug, on bowel habits and laxative consumption was studied in patients with idiopathic painless constipation and chronic laxative intake." | 9.06 | Treatment of chronic constipation with cisapride and placebo. ( Müller-Lissner, SA, 1987) |
| "A double-blind cross-over trial of oral cisapride 10 mg before meals and placebo was performed to determine its effects on colonic transit in patients with severe idiopathic constipation." | 9.06 | Cisapride accelerates colonic transit in constipated patients with colonic inertia. ( Fisher, RS; Krevsky, B; Malmud, LS; Maurer, AH, 1989) |
| "Twelve patients with chronic constipation refractory to the vigorous use of emollients, enemas, and/or laxatives were chosen for study of the investigational prokinetic agent, Cisapride." | 9.06 | Cisapride for intractable constipation in children: observations from an open trial. ( Heitlinger, L; Li, BU; McClung, HJ; Murray, RD; Rehm, D, 1990) |
| "Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias." | 8.87 | Cisapride for intestinal constipation. ( Aboumarzouk, OM; Agarwal, T; Antakia, R; Nelson, RL; Shariff, U, 2011) |
| "Cisapride appears to be useful as therapy for chronic constipation that is not associated with underlying organic abnormalities or pregnancy and that is refractory to other treatments, such as increased dietary fiber intake or bulk laxatives." | 8.79 | Cisapride for the treatment of chronic idiopathic constipation. ( Beckwith, JV; Gardner, VY; Heyneman, CA, 1995) |
| "Cisapride is an effective drug in at least half of the patients with chronic idiopathic constipation." | 7.69 | Cisapride in chronic idiopathic constipation: clinical response and effect on colonic transit time. ( Bak, YT; Kim, JH; Lee, CH, 1996) |
| " We therefore compared two dosage regimens of cisapride with placebo over a period of 6 months in patients with evidence of gastrooesophageal reflux, initially treated with antisecretory medication, with regard to maintaining symptom relief and satisfaction with treatment." | 6.68 | The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997) |
| "Cisapride is a drug that causes increased release of acetylcholine in the myenteric plexus." | 5.29 | Cisapride treatment of constipation in Parkinson's disease. ( Jost, WH; Schimrigk, K, 1993) |
| "Treatment with cisapride 10 mg, 4 times daily improved her condition, and this was associated with improved small intestinal motility during a 12-hour examination using a computer aided system." | 5.28 | Cisapride stimulates small intestinal motility and relieves constipation in myelopathy due to cervical spinal stenosis: case report. ( Aly, A; Hellström, PM; Johansson, C, 1990) |
| "Treatment with cisapride (4 x 10 mg daily) was undertaken." | 5.27 | Effects of cisapride on constipation due to a neurological lesion. ( de Groot, GH; de Pagter, GF, 1988) |
| "Previous studies with cisapride reported conflicting results in patients with constipation-predominant irritable bowel syndrome (IBS)." | 5.11 | Cisapride treatment of constipation-predominant irritable bowel syndrome is not superior to placebo. ( Kruis, W; Ziegenhagen, DJ, 2004) |
| "The effects of cisapride (10 mg three times daily) on the stool evacuation characteristics, laxative consumption (symptom diary) and motility pattern (rectoanal manometry) were assessed in patients with chronic idiopathic constipation who fulfilled Rome II criteria." | 5.10 | The efficacy of cisapride vs. placebo and diet in patients with chronic constipation. ( Altabas, K; Bilić, A; Dorosulić, Z; Jurcić, D; Mihanović, M; Restek-Petrović, B; Sunić-Omejc, M; Tolj, N, 2003) |
| "A randomised, double blind, placebo controlled, crossover design was used to examine the effects of cisapride (10 mg four times daily) on gall bladder emptying, mouth to caecum and large bowel transit times, and the proportions of deoxycholic acid and other bile acids, in fasting serum from: (i) control subjects (n=6), (ii) acromegalic patients not treated with octreotide (n=6), (iii) acromegalics on long term octreotide (n=8), and (iv) patients with constipation (n=8)." | 5.09 | Effects of cisapride on gall bladder emptying, intestinal transit, and serum deoxycholate: a prospective, randomised, double blind, placebo controlled trial. ( Besser, GM; Dowling, RH; Jenkins, PJ; Malcolm, P; Mallet, AI; Murphy, GM; Veysey, MJ, 2001) |
| "Cisapride was effective in the treatment of children with constipation." | 5.09 | Cisapride for the treatment of constipation in children: A double-blind study. ( Garcia-Aranda, JA; Nurko, S; Worona, LB; Zlochisty, O, 2000) |
| "Cisapride may have a role in the management of chronic idiopathic constipation in children." | 5.09 | Cisapride in management of chronic pediatric constipation. ( Halabi, IM, 1999) |
| "These results indicate that cisapride is not superior to placebo in the treatment of constipation and abdominal discomfort as components of irritable bowel syndrome." | 5.08 | Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome. ( Brandstätter, G; Dragosics, B; Hentschel, E; Judmaier, G; Schütze, K, 1997) |
| "We demonstrated pharmacokinetic characteristics of cisapride in elderly patients (85+/-6 years) who had suffered from constipation based on intestinal motility dysfunction." | 5.08 | Pharmacokinetic characteristics of cisapride in elderly patients. ( Koike, Y; Kuyama, Y; Mineshita, S; Sanaka, M; Takano, K; Yamamoto, T; Yamanaka, M, 1998) |
| "This study confirmed the efficacy of cisapride in chronic idiopathic constipation." | 5.08 | Cisapride in chronic idiopathic constipation: can the colon be re-educated? Bavarian Constipation Study Group. ( Müller-Lissner, SA, 1995) |
| "The data suggest that cisapride might be a useful adjunctive measure in treating a subset of SCI patients with colonic inertia, but a larger study is needed before this can be routinely recommended." | 5.08 | The effect of cisapride on segmental colonic transit time in patients with spinal cord injury. ( Bauman, WA; Gaing, A; Geders, JM; Korsten, MA, 1995) |
| "To establish whether cisapride is beneficial in children with intractable constipation, an open trial was performed." | 5.08 | Treatment of intractable constipation in children: experience with cisapride. ( Garcia-Aranda, JA; Guerrero, VY; Nurko, S; Worona, LB, 1996) |
| "The efficacy of cisapride as a treatment for chronic constipation in children with severe brain damage was studied in 20 children." | 5.08 | Cisapride in neurologically impaired children with chronic constipation. ( Del Giudice, E; Marino, A; Miele, E; Simeone, D; Staiano, A, 1996) |
| "This study did not demonstrate a clinical role for the use of cisapride in the treatment of idiopathic constipation in children." | 5.08 | Use of cisapride in treatment of constipation in children. ( Doig, C; Miller, V; Odeka, EB; Sagher, F, 1997) |
| "Oral cisapride influences interdigestive and post-prandial small bowel motor activity in both irritable bowel syndrome patients and healthy subjects; the effects of cisapride may be more marked in patients with predominant diarrhoea than in patients with predominant constipation." | 5.08 | Effects of oral cisapride on small bowel motility in irritable bowel syndrome. ( Bak, YT; Evans, PR; Kellow, JE, 1997) |
| "Cisapride improves symptoms in patients with idiopathic constipation." | 5.08 | The symptomatic effect of cisapride in patients with irritable bowel syndrome and constipation. ( Farup, PG; Hovde, O; Hovdenak, N; Lange, OJ; Trondstad, R; Wetterhus, S, 1998) |
| "The effects of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome (IBS) were evaluated in a randomized, double-blind, placebo-controlled study." | 5.07 | "Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride. ( Milo, R; Toussaint, J; Van Eeghem, P; Van Outryve, M, 1991) |
| "The efficacy of cisapride, a new prokinetic drug, as a treatment for chronic functional constipation of childhood was studied in 20 constipated children." | 5.07 | Effect of cisapride on chronic idiopathic constipation in children. ( Andreotti, MR; Cucchiara, S; Manzi, G; Minella, R; Staiano, A, 1991) |
| "Twelve patients with chronic constipation refractory to the vigorous use of emollients, enemas, and/or laxatives were chosen for study of the investigational prokinetic agent, Cisapride." | 5.06 | Cisapride for intractable constipation in children: observations from an open trial. ( Heitlinger, L; Li, BU; McClung, HJ; Murray, RD; Rehm, D, 1990) |
| "A double-blind cross-over trial of oral cisapride 10 mg before meals and placebo was performed to determine its effects on colonic transit in patients with severe idiopathic constipation." | 5.06 | Cisapride accelerates colonic transit in constipated patients with colonic inertia. ( Fisher, RS; Krevsky, B; Malmud, LS; Maurer, AH, 1989) |
| "The effect of cisapride (20 mg bid), a new prokinetic drug, on bowel habits and laxative consumption was studied in patients with idiopathic painless constipation and chronic laxative intake." | 5.06 | Treatment of chronic constipation with cisapride and placebo. ( Müller-Lissner, SA, 1987) |
| "Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease." | 4.90 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Cody, JD; Coggrave, M; Norton, C, 2014) |
| "Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease." | 4.89 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C, 2013) |
| "Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias." | 4.87 | Cisapride for intestinal constipation. ( Aboumarzouk, OM; Agarwal, T; Antakia, R; Nelson, RL; Shariff, U, 2011) |
| " Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (three trials)." | 4.83 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C; Wiesel, PH, 2006) |
| " Problems have arisen with alosetron being associated with ischaemic colitis and a high incidence of constipation." | 4.81 | Pharmacological treatment of irritable bowel syndrome--from concept to sales. ( Kamm, MA, 2002) |
| " Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (two trials)." | 4.81 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Brazzelli, M; Norton, C; Wiesel, PH, 2001) |
| "This paper provides a comprehensive review of the current knowledge on cisapride in different clinical conditions in children: different manifestations of gastro-oesophageal reflux, such as (excessive) regurgitation, oesophagitis, chronic respiratory disease or uncontrolled asthma, cystic fibrosis, chronic dyspepsia, constipation and pseudo-obstruction, and as an aid to small bowel capsule-biopsy." | 4.80 | Clinical use of cisapride and its risk-benefit in paediatric patients. ( Vandenplas, Y, 1998) |
| "Cisapride appears to be useful as therapy for chronic constipation that is not associated with underlying organic abnormalities or pregnancy and that is refractory to other treatments, such as increased dietary fiber intake or bulk laxatives." | 4.79 | Cisapride for the treatment of chronic idiopathic constipation. ( Beckwith, JV; Gardner, VY; Heyneman, CA, 1995) |
| "A 12-year-old male castrated domestic shorthair developed chronic urinary retention, constipation and a decreased perineal reflex following a single lumbo-sacral epidural injection of morphine during general anesthesia." | 3.77 | Suspected epidural morphine analgesia induced chronic urinary and bowel dysfunction in a cat. ( Callan, MB; Cross, JR; Golder, FJ; Song, RB, 2011) |
| " In a pilot study, we investigated the action of the gastrointestinal prokinetic drug cisapride on gastric emptying in seven premature infants, of whom four suffered from gastric stasis and three had constipation." | 3.71 | Improved use of the [13C]octanoic acid breath test as intra-individual parameter to study the effect of a prokinetic drug on gastric emptying in preterm infants with oral feeding intolerance. ( Cranendonk, A; Kneepkens, CM; Kulik, W; Lafeber, HN; Menelik, N; van Weissenbruch, MM, 2001) |
| "Cisapride is an effective drug in at least half of the patients with chronic idiopathic constipation." | 3.69 | Cisapride in chronic idiopathic constipation: clinical response and effect on colonic transit time. ( Bak, YT; Kim, JH; Lee, CH, 1996) |
| "The total effective rate and recurrence rate of the treated group were superior to those of the control group significantly (P < 0." | 2.71 | Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome. ( Chen, G; Ding, SQ; Ha, NL; Ye, H; Yu, SP, 2005) |
| "Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon." | 2.70 | Effects of cisapride on colonic transit in patients with progressive systemic sclerosis. ( Chen, DY; Chen, YH; Hsieh, TY; Lan, JL; Lin, WY; Wang, SJ, 2002) |
| " We therefore compared two dosage regimens of cisapride with placebo over a period of 6 months in patients with evidence of gastrooesophageal reflux, initially treated with antisecretory medication, with regard to maintaining symptom relief and satisfaction with treatment." | 2.68 | The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997) |
| "Constipation is one of the most common gastrointestinal disorders with a prevalence up to 16." | 2.53 | [Current Status of Translational Research on Constipation]. ( Lee, HJ; Park, KS, 2016) |
| "Constipation is a common pediatric problem." | 2.43 | Evaluation and treatment of constipation in children: summary of updated recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. ( , 2006) |
| "Cisapride was either equal to or superior to metoclopramide in relieving reflux symptoms." | 2.39 | Cisapride: a gastrointestinal prokinetic drug. ( Barone, JA; Bierman, RH; Colaizzi, JL; Jessen, LM, 1994) |
| " Similar dose-response activity was obtained for a control group consisting of six patients undergoing resection for colorectal carcinoma." | 1.30 | Abnormalities in the contractile properties of colonic smooth muscle in idiopathic slow transit constipation. ( Gillespie, JI; Slater, BJ; Varma, JS, 1997) |
| "A 46-year-old man with achalasia-like syndrome developed CREST syndrome 4 years later." | 1.29 | Achalasia-like syndrome as the first manifestation in a patient with CREST syndrome. ( Berenguer, J; Gálvez, C; Garrigues, V; Ponce, J; Valverde, J, 1996) |
| "Cisapride was well tolerated and thus appears to be a useful option in the treatment of functional digestive disorders in a general practice setting." | 1.29 | Functional dyspepsia versus other functional gastrointestinal disorders: a practical approach in Belgian general practices. ( Cardon, E; Jaecques, N; Lebrun, F; Meurant, JP; Rombouts, J; Spaepen, W; Verhaeghe, J, 1993) |
| "Cisapride is a drug that causes increased release of acetylcholine in the myenteric plexus." | 1.29 | Cisapride treatment of constipation in Parkinson's disease. ( Jost, WH; Schimrigk, K, 1993) |
| "Treatment with cisapride 10 mg, 4 times daily improved her condition, and this was associated with improved small intestinal motility during a 12-hour examination using a computer aided system." | 1.28 | Cisapride stimulates small intestinal motility and relieves constipation in myelopathy due to cervical spinal stenosis: case report. ( Aly, A; Hellström, PM; Johansson, C, 1990) |
| "Treatment with cisapride (4 x 10 mg daily) was undertaken." | 1.27 | Effects of cisapride on constipation due to a neurological lesion. ( de Groot, GH; de Pagter, GF, 1988) |
| "Treatment with Cisapride (R 51 619, Janssen Pharmaceutica) was undertaken in an attempt to increase colonic motility and to reduce urinary retention." | 1.27 | Treatment with cisapride of the gastrointestinal and urological sequelae of spinal cord transection: case report. ( Brassinne, A; Etienne, M; Verlinden, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (12.82) | 18.7374 |
| 1990's | 38 (48.72) | 18.2507 |
| 2000's | 22 (28.21) | 29.6817 |
| 2010's | 7 (8.97) | 24.3611 |
| 2020's | 1 (1.28) | 2.80 |
| Authors | Studies |
|---|---|
| Carroll, W | 1 |
| Green, J | 1 |
| Gilchrist, FJ | 1 |
| Li, DY | 1 |
| Dai, YK | 1 |
| Zhang, YZ | 1 |
| Huang, MX | 1 |
| Li, RL | 1 |
| Ou-Yang, J | 1 |
| Chen, WJ | 1 |
| Hu, L | 1 |
| Coggrave, M | 3 |
| Norton, C | 4 |
| Cody, JD | 1 |
| Lee, HJ | 1 |
| Park, KS | 1 |
| Boyle, G | 1 |
| Mounsey, A | 1 |
| Crowell, K | 1 |
| Aboumarzouk, OM | 1 |
| Agarwal, T | 1 |
| Antakia, R | 1 |
| Shariff, U | 1 |
| Nelson, RL | 1 |
| Song, RB | 1 |
| Cross, JR | 1 |
| Golder, FJ | 1 |
| Callan, MB | 1 |
| Bove, A | 1 |
| Bellini, M | 1 |
| Battaglia, E | 1 |
| Bocchini, R | 1 |
| Gambaccini, D | 1 |
| Bove, V | 1 |
| Pucciani, F | 1 |
| Altomare, DF | 1 |
| Dodi, G | 1 |
| Sciaudone, G | 1 |
| Falletto, E | 1 |
| Piloni, V | 1 |
| Wang, SJ | 1 |
| Lan, JL | 2 |
| Chen, DY | 1 |
| Chen, YH | 1 |
| Hsieh, TY | 1 |
| Lin, WY | 1 |
| Rubin, G | 4 |
| Rubin, GP | 1 |
| Altabas, K | 1 |
| Bilić, A | 1 |
| Jurcić, D | 1 |
| Dorosulić, Z | 1 |
| Mihanović, M | 1 |
| Sunić-Omejc, M | 1 |
| Restek-Petrović, B | 1 |
| Tolj, N | 1 |
| Schimpl, G | 1 |
| Uray, E | 1 |
| Ratschek, M | 1 |
| Höllwarth, ME | 1 |
| Ziegenhagen, DJ | 1 |
| Kruis, W | 1 |
| Yu, SP | 1 |
| Ye, H | 1 |
| Ha, NL | 1 |
| Ding, SQ | 1 |
| Chen, G | 1 |
| Kamm, MA | 1 |
| Wiesel, PH | 2 |
| Hanauer, SB | 1 |
| Reboa, G | 1 |
| Arnulfo, G | 1 |
| Frascio, M | 1 |
| Di Somma, C | 1 |
| Pitto, G | 1 |
| Berti-Riboli, E | 1 |
| Jost, WH | 3 |
| Schimrigk, K | 3 |
| Geders, JM | 1 |
| Gaing, A | 1 |
| Bauman, WA | 1 |
| Korsten, MA | 1 |
| Müller-Lissner, SA | 2 |
| Barone, JA | 1 |
| Jessen, LM | 1 |
| Colaizzi, JL | 1 |
| Bierman, RH | 1 |
| Verhaeghe, J | 1 |
| Jaecques, N | 1 |
| Rombouts, J | 1 |
| Spaepen, W | 1 |
| Cardon, E | 1 |
| Lebrun, F | 1 |
| Meurant, JP | 1 |
| McCauley, MD | 1 |
| Gardner, VY | 1 |
| Beckwith, JV | 1 |
| Heyneman, CA | 1 |
| Meier, C | 1 |
| Hess, C | 1 |
| Meier-Abt, PJ | 1 |
| Krähenbühl, S | 1 |
| Longo, WE | 1 |
| Woolsey, RM | 1 |
| Vernava, AM | 1 |
| Virgo, KS | 1 |
| McKirgan, L | 1 |
| Johnson, FE | 1 |
| Staiano, A | 2 |
| Del Giudice, E | 1 |
| Simeone, D | 1 |
| Miele, E | 1 |
| Marino, A | 1 |
| Cucchiara, S | 2 |
| Garrigues, V | 1 |
| Ponce, J | 1 |
| Gálvez, C | 1 |
| Valverde, J | 1 |
| Berenguer, J | 1 |
| Loening-Baucke, V | 2 |
| Nurko, S | 3 |
| Garcia-Aranda, JA | 2 |
| Guerrero, VY | 1 |
| Worona, LB | 2 |
| Bak, YT | 2 |
| Kim, JH | 1 |
| Lee, CH | 1 |
| Slater, BJ | 1 |
| Varma, JS | 1 |
| Gillespie, JI | 1 |
| Schütze, K | 1 |
| Brandstätter, G | 1 |
| Dragosics, B | 1 |
| Judmaier, G | 1 |
| Hentschel, E | 1 |
| Odeka, EB | 2 |
| Sagher, F | 1 |
| Miller, V | 2 |
| Doig, C | 1 |
| Evans, PR | 1 |
| Kellow, JE | 1 |
| Hatlebakk, JG | 1 |
| Johnsson, F | 1 |
| Vilien, M | 1 |
| Carling, L | 1 |
| Wetterhus, S | 2 |
| Thøgersen, T | 1 |
| Farup, PG | 1 |
| Hovdenak, N | 1 |
| Lange, OJ | 1 |
| Hovde, O | 1 |
| Trondstad, R | 1 |
| Yamamoto, T | 1 |
| Takano, K | 1 |
| Sanaka, M | 1 |
| Kuyama, Y | 1 |
| Yamanaka, M | 1 |
| Koike, Y | 1 |
| Mineshita, S | 1 |
| Hoekstra, JH | 1 |
| König, B | 1 |
| Vandenplas, Y | 2 |
| Halabi, IM | 1 |
| Sanger, GJ | 1 |
| Zlochisty, O | 1 |
| Bhatnagar, SK | 1 |
| Kulik, W | 1 |
| van Weissenbruch, MM | 1 |
| Menelik, N | 1 |
| Cranendonk, A | 1 |
| Kneepkens, CM | 1 |
| Lafeber, HN | 1 |
| Brazzelli, M | 1 |
| Veysey, MJ | 1 |
| Malcolm, P | 1 |
| Mallet, AI | 1 |
| Jenkins, PJ | 1 |
| Besser, GM | 1 |
| Murphy, GM | 1 |
| Dowling, RH | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Van Outryve, M | 1 |
| Milo, R | 1 |
| Toussaint, J | 1 |
| Van Eeghem, P | 1 |
| Andreotti, MR | 1 |
| Minella, R | 1 |
| Manzi, G | 1 |
| Hellström, PM | 1 |
| Aly, A | 1 |
| Johansson, C | 1 |
| Murray, RD | 1 |
| Li, BU | 1 |
| McClung, HJ | 1 |
| Heitlinger, L | 1 |
| Rehm, D | 1 |
| Fink, S | 1 |
| Chaudhuri, TK | 1 |
| Palmer, JD | 1 |
| Fraitag, B | 1 |
| Cloarec, D | 1 |
| Galmiche, JP | 1 |
| Krevsky, B | 1 |
| Maurer, AH | 1 |
| Malmud, LS | 1 |
| Fisher, RS | 1 |
| Kasicka, A | 1 |
| Jonderko, K | 1 |
| Ewe, K | 1 |
| Graham, JR | 1 |
| Binnie, NR | 1 |
| Creasey, GH | 1 |
| Edmond, P | 1 |
| Smith, AN | 1 |
| de Groot, GH | 1 |
| de Pagter, GF | 1 |
| Etienne, M | 1 |
| Verlinden, M | 1 |
| Brassinne, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neurogenic Bowel Dysfunction: Evaluation of the Effects of Osteopathic Manipulative Treatment in People With Central Nervous System Injury[NCT04127617] | 70 participants (Anticipated) | Interventional | 2019-10-28 | Recruiting | |||
| Automatic Colon-specific Massage With MOWOOT Medical Device to Treat Chronic Constipation in Adults[NCT04262752] | 100 participants (Actual) | Interventional | 2018-01-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 reviews available for cisapride and Constipation
| Article | Year |
|---|---|
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Topics: Cisapride; Constipation; Cystic Fibrosis; Humans; Intestinal Obstruction; Quality of Life; Randomize | 2021 |
Systematic review and meta-analysis of traditional Chinese medicine in the treatment of constipation-predominant irritable bowel syndrome.
Topics: Benzamides; Cisapride; Constipation; Humans; Irritable Bowel Syndrome; Medicine, Chinese Traditional | 2017 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Adult; Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestina | 2013 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2014 |
[Current Status of Translational Research on Constipation].
Topics: Animals; Cisapride; Colon; Constipation; Disease Models, Animal; Humans; Interstitial Cells of Cajal | 2016 |
Cisapride for intestinal constipation.
Topics: Adult; Arrhythmias, Cardiac; Child; Cisapride; Constipation; Female; Gastrointestinal Agents; Humans | 2011 |
Constipation.
Topics: Biofeedback, Psychology; Cathartics; Child; Cisapride; Constipation; Humans; Infant; Randomized Cont | 2002 |
Constipation.
Topics: Biofeedback, Psychology; Cathartics; Child; Cisapride; Constipation; Humans; Infant; Toilet Training | 2002 |
Constipation in children.
Topics: Adolescent; Cathartics; Child; Child, Preschool; Cisapride; Constipation; Dietary Fiber; Gastrointes | 2003 |
Constipation in children.
Topics: Cathartics; Child; Cisapride; Constipation; Dietary Fiber; Gastrointestinal Agents; Humans | 2004 |
Pharmacological treatment of irritable bowel syndrome--from concept to sales.
Topics: Antidepressive Agents; Benzofurans; Carbolines; Cisapride; Constipation; Drug Industry; Gastrointest | 2002 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2006 |
Evaluation and treatment of constipation in children: summary of updated recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.
Topics: Animals; Biofeedback, Psychology; Cattle; Child; Cisapride; Constipation; Dietary Fiber; Gastroenter | 2006 |
Cisapride: a gastrointestinal prokinetic drug.
Topics: Adult; Anti-Ulcer Agents; Cisapride; Clinical Trials as Topic; Constipation; Double-Blind Method; Dy | 1994 |
Cisapride for the treatment of chronic idiopathic constipation.
Topics: Chronic Disease; Cisapride; Clinical Trials as Topic; Constipation; Female; Gastrointestinal Agents; | 1995 |
Cisapride therapy for gastrointestinal disease.
Topics: Adult; Animals; Child; Cisapride; Constipation; Esophageal Motility Disorders; Gastrointestinal Dise | 1996 |
Clinical use of cisapride and its risk-benefit in paediatric patients.
Topics: Child; Child, Preschool; Cisapride; Constipation; Cystic Fibrosis; Drug Interactions; Dyspepsia; Fec | 1998 |
Hypersensitivity and hyperreactivity in the irritable bowel syndrome: An opportunity for drug discovery.
Topics: Abdominal Pain; Afferent Pathways; Animals; Cisapride; Colonic Diseases, Functional; Constipation; D | 1999 |
Advances in the management of pediatric constipation.
Topics: Biofeedback, Psychology; Child; Child, Preschool; Cisapride; Constipation; Gastrointestinal Agents; | 2000 |
Controversies in the management of chronic constipation.
Topics: Cathartics; Child; Chronic Disease; Cisapride; Constipation; Dietary Fiber; Feedback; Gastrointestin | 2001 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2001 |
[Cisapride: pharmacology, current therapeutic results and future prospects].
Topics: Cisapride; Constipation; Dyspepsia; Esophagitis; Esophagus; Forecasting; Gastric Emptying; Gastroeso | 1989 |
[Cisapride--a new drug effective in the treatment of disorders of gastrointestinal motility].
Topics: Cisapride; Constipation; Drug Evaluation; Gastrointestinal Motility; Humans; Piperidines | 1989 |
[Therapy of obstipation].
Topics: Biofeedback, Psychology; Cathartics; Chronic Disease; Cisapride; Constipation; Humans; Narcotic Anta | 1989 |
28 trials available for cisapride and Constipation
| Article | Year |
|---|---|
Effects of cisapride on colonic transit in patients with progressive systemic sclerosis.
Topics: Adult; Aged; Cisapride; Colon; Constipation; Female; Gastrointestinal Agents; Gastrointestinal Trans | 2002 |
The efficacy of cisapride vs. placebo and diet in patients with chronic constipation.
Topics: Adult; Aged; Chronic Disease; Cisapride; Constipation; Diet; Female; Gastrointestinal Agents; Humans | 2003 |
Cisapride treatment of constipation-predominant irritable bowel syndrome is not superior to placebo.
Topics: Adolescent; Adult; Aged; Cisapride; Constipation; Female; Gastrointestinal Agents; Humans; Irritable | 2004 |
Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome.
Topics: Adult; Aged; Anal Canal; Cisapride; Constipation; Female; Follow-Up Studies; Gastrointestinal Agents | 2005 |
Colon motility and colo-anal reflexes in chronic idiopathic constipation. Effects of a novel enterokinetic agent cisapride.
Topics: Adult; Aged; Anal Canal; Cathartics; Cisapride; Colon; Constipation; Female; Gastrointestinal Agents | 1984 |
The effect of cisapride on delayed colonic transit time in patients with idiopathic Parkinson's disease.
Topics: Aged; Aged, 80 and over; Cisapride; Colon; Constipation; Cross-Over Studies; Double-Blind Method; Fe | 1994 |
The effect of cisapride on segmental colonic transit time in patients with spinal cord injury.
Topics: Adult; Aged; Cisapride; Colon; Constipation; Double-Blind Method; Gastrointestinal Transit; Humans; | 1995 |
Cisapride in chronic idiopathic constipation: can the colon be re-educated? Bavarian Constipation Study Group.
Topics: Adult; Chronic Disease; Cisapride; Colon; Constipation; Defecation; Double-Blind Method; Humans; Pip | 1995 |
Cisapride in neurologically impaired children with chronic constipation.
Topics: Brain Damage, Chronic; Child; Child, Preschool; Chronic Disease; Cisapride; Constipation; Defecation | 1996 |
Cisapride for children with intractable constipation: an interim verdict!
Topics: Adult; Autonomic Agents; Child; Cisapride; Constipation; Humans; Piperidines; Serotonin Agents | 1996 |
Treatment of intractable constipation in children: experience with cisapride.
Topics: Anal Canal; Child; Child, Preschool; Cisapride; Constipation; Female; Humans; Male; Manometry; Piper | 1996 |
Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Doub | 1997 |
Use of cisapride in treatment of constipation in children.
Topics: Adolescent; Child; Child, Preschool; Cisapride; Constipation; Defecation; Double-Blind Method; Femal | 1997 |
Use of cisapride in treatment of idiopathic constipation in children.
Topics: Child; Cisapride; Constipation; Double-Blind Method; Gastrointestinal Agents; Humans; Piperidines | 1997 |
Effects of oral cisapride on small bowel motility in irritable bowel syndrome.
Topics: Adult; Cisapride; Colonic Diseases, Functional; Constipation; Diarrhea; Eating; Female; Gastrointest | 1997 |
The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease.
Topics: Abdominal Pain; Cisapride; Constipation; Diarrhea; Drug Administration Schedule; Endoscopy; Esophagi | 1997 |
The symptomatic effect of cisapride in patients with irritable bowel syndrome and constipation.
Topics: Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Double-Blind Method; | 1998 |
Pharmacokinetic characteristics of cisapride in elderly patients.
Topics: Administration, Oral; Aged; Aged, 80 and over; Area Under Curve; Biological Availability; Cisapride; | 1998 |
Cisapride in management of chronic pediatric constipation.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Cisapride; Constipation; Double-Blind Method; | 1999 |
Cisapride for the treatment of constipation in children: A double-blind study.
Topics: Adolescent; Analysis of Variance; Cathartics; Chi-Square Distribution; Child; Child, Preschool; Chro | 2000 |
Cisapride for the treatment of constipation in children.
Topics: Adolescent; Child; Child, Preschool; Cisapride; Constipation; Double-Blind Method; Gastrointestinal | 2000 |
Effects of cisapride on gall bladder emptying, intestinal transit, and serum deoxycholate: a prospective, randomised, double blind, placebo controlled trial.
Topics: Acromegaly; Adult; Cholelithiasis; Cholic Acid; Cisapride; Constipation; Cross-Over Studies; Deoxych | 2001 |
"Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Defe | 1991 |
Effect of cisapride on chronic idiopathic constipation in children.
Topics: Child; Child, Preschool; Cisapride; Constipation; Double-Blind Method; Female; Gastrointestinal Moti | 1991 |
[Treatment of chronic-obstructive upper abdominal complaints. Outlook. Further hypothetical indications].
Topics: Cisapride; Clinical Trials as Topic; Constipation; Dyspepsia; Gastroesophageal Reflux; Gastrointesti | 1990 |
Cisapride for intractable constipation in children: observations from an open trial.
Topics: Adolescent; Anal Canal; Child; Child, Preschool; Chronic Disease; Cisapride; Constipation; Encopresi | 1990 |
Cisapride accelerates colonic transit in constipated patients with colonic inertia.
Topics: Adult; Cisapride; Clinical Trials as Topic; Colon; Constipation; Double-Blind Method; Female; Gastro | 1989 |
Treatment of chronic constipation with cisapride and placebo.
Topics: Cathartics; Chronic Disease; Cisapride; Clinical Trials as Topic; Constipation; Consumer Behavior; D | 1987 |
26 other studies available for cisapride and Constipation
| Article | Year |
|---|---|
Clinical inquiries: what is the role of prokinetic agents for constipation?
Topics: Cisapride; Constipation; Gastrointestinal Agents; Humans; Indoles | 2009 |
Suspected epidural morphine analgesia induced chronic urinary and bowel dysfunction in a cat.
Topics: Anesthesia, Epidural; Animals; Cat Diseases; Cats; Cisapride; Constipation; Gastrointestinal Agents; | 2011 |
Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation (part II: treatment).
Topics: Chronic Disease; Cisapride; Clinical Trials as Topic; Colectomy; Constipation; Dietary Fiber; Gastro | 2012 |
Childhood constipation.
Topics: Biofeedback, Psychology; Cathartics; Child; Cisapride; Constipation; Humans; Lactulose | 2003 |
Constipation and intestinal neuronal dysplasia type B: a clinical follow-up study.
Topics: Age of Onset; Cathartics; Child, Preschool; Cisapride; Constipation; Defecation; Female; Follow-Up S | 2004 |
Moving ahead or falling behind?
Topics: Cisapride; Constipation; Domperidone; Gastrointestinal Agents; Gastrointestinal Diseases; Gastrointe | 2007 |
Cisapride treatment of constipation in Parkinson's disease.
Topics: Acetylcholine; Aged; Autonomic Nervous System; Cisapride; Constipation; Female; Humans; Male; Middle | 1993 |
Functional dyspepsia versus other functional gastrointestinal disorders: a practical approach in Belgian general practices.
Topics: Adult; Aged; Belgium; Cisapride; Cluster Analysis; Constipation; Dyspepsia; Family Practice; Female; | 1993 |
Dosage consideration for cisapride.
Topics: Animals; Cat Diseases; Cats; Cisapride; Constipation; Female; Parasympathomimetics; Piperidines | 1996 |
[A clinical-pharmacological case (1). Action of cisapride (Prepulsid) on bladder function].
Topics: Aged; Cisapride; Constipation; Humans; Male; Parasympathomimetics; Piperidines; Spinal Cord Injuries | 1996 |
Cisapride for constipation in spinal cord injured patients: a preliminary report.
Topics: Cisapride; Colostomy; Constipation; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Man | 1995 |
Achalasia-like syndrome as the first manifestation in a patient with CREST syndrome.
Topics: Anti-Ulcer Agents; Cardia; Cisapride; Constipation; CREST Syndrome; Dilatation; Esophageal Achalasia | 1996 |
Cisapride in chronic idiopathic constipation: clinical response and effect on colonic transit time.
Topics: Adult; Chronic Disease; Cisapride; Colon; Constipation; Female; Gastrointestinal Motility; Humans; M | 1996 |
Abnormalities in the contractile properties of colonic smooth muscle in idiopathic slow transit constipation.
Topics: Adolescent; Adult; Aged; Carbachol; Cisapride; Colorectal Neoplasms; Constipation; Female; Gastroint | 1997 |
Long-term results with cisapride in Parkinson's disease.
Topics: Aged; Cathartics; Cisapride; Constipation; Female; Humans; Male; Middle Aged; Parkinson Disease; Per | 1997 |
Sorbitol in oral liquid cisapride.
Topics: Adult; Cathartics; Child; Cisapride; Constipation; Gastrointestinal Agents; Humans; Sorbitol | 1998 |
[Prokinetic drug more effective than laxatives. Despite multiple sclerosis, no enema].
Topics: Adult; Cisapride; Constipation; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema | 1998 |
Cisapride in constipation.
Topics: Cisapride; Constipation; Gastrointestinal Agents; Humans | 1999 |
Improved use of the [13C]octanoic acid breath test as intra-individual parameter to study the effect of a prokinetic drug on gastric emptying in preterm infants with oral feeding intolerance.
Topics: Breath Tests; Caprylates; Carbon Isotopes; Cisapride; Constipation; Gastric Emptying; Gastrointestin | 2001 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Cisapride stimulates small intestinal motility and relieves constipation in myelopathy due to cervical spinal stenosis: case report.
Topics: Cisapride; Constipation; Female; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Intest | 1990 |
Cisapride accelerates colonic transit in constipated patients with colonic inertia.
Topics: Cisapride; Colon; Constipation; Gastrointestinal Transit; Humans; Piperidines; Serotonin Antagonists | 1990 |
Cisapride for severe non-ulcer dyspepsia, pseudoobstruction and constipation.
Topics: Adult; Aged; Cisapride; Constipation; Dyspepsia; Female; Humans; Intestinal Pseudo-Obstruction; Male | 1989 |
The action of cisapride on the chronic constipation of paraplegia.
Topics: Administration, Oral; Adult; Anal Canal; Chronic Disease; Cisapride; Constipation; Female; Gastroint | 1988 |
Effects of cisapride on constipation due to a neurological lesion.
Topics: Adult; Chronic Disease; Cisapride; Constipation; Dose-Response Relationship, Drug; Gastrointestinal | 1988 |
Treatment with cisapride of the gastrointestinal and urological sequelae of spinal cord transection: case report.
Topics: Bisacodyl; Cisapride; Constipation; Drug Administration Schedule; Drug Therapy, Combination; Humans; | 1988 |