Page last updated: 2024-10-25

cisapride and Complications, Pregnancy

cisapride has been researched along with Complications, Pregnancy in 2 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
"The objective of this prospective multicenter study was to determine whether cisapride is associated with increased risk of malformations, spontaneous abortions, or decreased birthweight when used during pregnancy."7.69Cisapride use during human pregnancy: a prospective, controlled multicenter study. ( Addis, A; Bailey, B; Bonati, M; Conover, B; De Souza, CF; Garbis, H; Koren, G; Lau, M; Lee, A; Mastroiacovo, P; Matsui, D; Mazzone, T; Paolini, C; Sanghvi, K; Schechtman, AS; Val, T, 1997)
"The objective of this prospective multicenter study was to determine whether cisapride is associated with increased risk of malformations, spontaneous abortions, or decreased birthweight when used during pregnancy."3.69Cisapride use during human pregnancy: a prospective, controlled multicenter study. ( Addis, A; Bailey, B; Bonati, M; Conover, B; De Souza, CF; Garbis, H; Koren, G; Lau, M; Lee, A; Mastroiacovo, P; Matsui, D; Mazzone, T; Paolini, C; Sanghvi, K; Schechtman, AS; Val, T, 1997)
"Heartburn is a normal consequence of pregnancy."2.43Review article: the management of heartburn in pregnancy. ( Richter, JE, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Richter, JE1
Bailey, B1
Addis, A1
Lee, A1
Sanghvi, K1
Mastroiacovo, P1
Mazzone, T1
Bonati, M1
Paolini, C1
Garbis, H1
Val, T1
De Souza, CF1
Matsui, D1
Schechtman, AS1
Conover, B1
Lau, M1
Koren, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Efficacy of Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy : A Randomized Double-Blind Controlled Trial[NCT02470117]Phase 4100 participants (Actual)Interventional2015-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cisapride and Complications, Pregnancy

ArticleYear
Review article: the management of heartburn in pregnancy.
    Alimentary pharmacology & therapeutics, 2005, Nov-01, Volume: 22, Issue:9

    Topics: Antacids; Anti-Ulcer Agents; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Motility;

2005

Other Studies

1 other study available for cisapride and Complications, Pregnancy

ArticleYear
Cisapride use during human pregnancy: a prospective, controlled multicenter study.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:9

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Birth Weight; Case-Control Studies; Cisap

1997