cisapride has been researched along with Colonic Diseases, Functional in 15 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effect of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome." | 9.08 | Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome. ( Brandstätter, G; Dragosics, B; Hentschel, E; Judmaier, G; Schütze, K, 1997) |
| "Cisapride improves symptoms in patients with idiopathic constipation." | 9.08 | The symptomatic effect of cisapride in patients with irritable bowel syndrome and constipation. ( Farup, PG; Hovde, O; Hovdenak, N; Lange, OJ; Trondstad, R; Wetterhus, S, 1998) |
| "The effects of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome (IBS) were evaluated in a randomized, double-blind, placebo-controlled study." | 9.07 | "Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride. ( Milo, R; Toussaint, J; Van Eeghem, P; Van Outryve, M, 1991) |
| "To study the effect of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome." | 5.08 | Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome. ( Brandstätter, G; Dragosics, B; Hentschel, E; Judmaier, G; Schütze, K, 1997) |
| "Cisapride has been reported to improve symptoms in patients with constipation-predominant irritable bowel syndrome." | 5.08 | Effects of oral cisapride on small bowel motility in irritable bowel syndrome. ( Bak, YT; Evans, PR; Kellow, JE, 1997) |
| "Cisapride improves symptoms in patients with idiopathic constipation." | 5.08 | The symptomatic effect of cisapride in patients with irritable bowel syndrome and constipation. ( Farup, PG; Hovde, O; Hovdenak, N; Lange, OJ; Trondstad, R; Wetterhus, S, 1998) |
| "The effects of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome (IBS) were evaluated in a randomized, double-blind, placebo-controlled study." | 5.07 | "Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride. ( Milo, R; Toussaint, J; Van Eeghem, P; Van Outryve, M, 1991) |
| "In cisapride-treated diarrhoea-predominant patients the mean contraction amplitude was higher (29." | 2.69 | Effects of cisapride on symptoms and postcibal small-bowel motor function in patients with irritable bowel syndrome. ( Campbell, FC; Hau, C; Loudon, MA; Noor, N; Small, PK, 1998) |
| "Functional gastrointestinal disorders are best understood by applying a bio-psycho-social model." | 2.40 | Today's therapy of functional gastrointestinal disorders--does it help? ( Berstad, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (80.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schütze, K | 1 |
| Brandstätter, G | 1 |
| Dragosics, B | 1 |
| Judmaier, G | 1 |
| Hentschel, E | 1 |
| Evans, PR | 1 |
| Bak, YT | 1 |
| Kellow, JE | 1 |
| Sheptulin, AA | 1 |
| Farup, PG | 1 |
| Hovdenak, N | 1 |
| Wetterhus, S | 1 |
| Lange, OJ | 1 |
| Hovde, O | 1 |
| Trondstad, R | 1 |
| Noor, N | 1 |
| Small, PK | 1 |
| Loudon, MA | 1 |
| Hau, C | 1 |
| Campbell, FC | 1 |
| Berstad, A | 1 |
| Mayer, EA | 1 |
| Lembo, T | 1 |
| Chang, L | 1 |
| Scarpignato, C | 1 |
| Pelosini, I | 1 |
| Sanger, GJ | 1 |
| Dunphy, RC | 1 |
| Verne, GN | 1 |
| Lindberg, M | 1 |
| Coffin, B | 1 |
| Cammarella, I | 1 |
| Ruggeri, R | 1 |
| Musca, A | 1 |
| Raedsch, R | 1 |
| Van Outryve, M | 1 |
| Milo, R | 1 |
| Toussaint, J | 1 |
| Van Eeghem, P | 1 |
8 reviews available for cisapride and Colonic Diseases, Functional
| Article | Year |
|---|---|
[Irritable bowel syndrome: current views on its pathogenesis, diagnosis and treatment].
Topics: Cisapride; Colonic Diseases, Functional; Diagnosis, Differential; Female; Gastrointestinal Agents; H | 1997 |
Today's therapy of functional gastrointestinal disorders--does it help?
Topics: Antacids; Benzyl Compounds; Cisapride; Clinical Trials as Topic; Colonic Diseases, Functional; Dyspe | 1998 |
Approaches to the modulation of abdominal pain.
Topics: Abdominal Pain; Animals; Antidepressive Agents, Tricyclic; Cisapride; Colonic Diseases, Functional; | 1999 |
Management of irritable bowel syndrome: novel approaches to the pharmacology of gut motility.
Topics: Animals; Cisapride; Colonic Diseases, Functional; Erythromycin; Gastrointestinal Agents; Gastrointes | 1999 |
Hypersensitivity and hyperreactivity in the irritable bowel syndrome: An opportunity for drug discovery.
Topics: Abdominal Pain; Afferent Pathways; Animals; Cisapride; Colonic Diseases, Functional; Constipation; D | 1999 |
Drug treatment options for irritable bowel syndrome: managing for success.
Topics: Aged; Antidiarrheals; Cisapride; Colonic Diseases, Functional; Dietary Fiber; Female; Gastrointestin | 2001 |
[Irritable colon. Physiopathologic and therapeutic aspects].
Topics: Antidepressive Agents; Cisapride; Colonic Diseases, Functional; Diet; Gastrointestinal Motility; Hum | 1992 |
[Meteorism and flatulence].
Topics: Cisapride; Colonic Diseases, Functional; Combined Modality Therapy; Flatulence; Gases; Humans; Intes | 1992 |
5 trials available for cisapride and Colonic Diseases, Functional
| Article | Year |
|---|---|
Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Doub | 1997 |
Effects of oral cisapride on small bowel motility in irritable bowel syndrome.
Topics: Adult; Cisapride; Colonic Diseases, Functional; Constipation; Diarrhea; Eating; Female; Gastrointest | 1997 |
The symptomatic effect of cisapride in patients with irritable bowel syndrome and constipation.
Topics: Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Double-Blind Method; | 1998 |
Effects of cisapride on symptoms and postcibal small-bowel motor function in patients with irritable bowel syndrome.
Topics: Adult; Cisapride; Colonic Diseases, Functional; Female; Gastrointestinal Agents; Gastrointestinal Mo | 1998 |
"Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Defe | 1991 |
2 other studies available for cisapride and Colonic Diseases, Functional
| Article | Year |
|---|---|
[Irritable colon].
Topics: Cisapride; Colonic Diseases, Functional; Gastrointestinal Agents; Humans; Serotonin Antagonists | 2001 |
[Colonic microflora and motility. Physiological data and during irritable bowel syndrome].
Topics: Animals; Antidiarrheals; Cisapride; Colon; Colonic Diseases, Functional; Cross-Over Studies; Fasting | 2001 |