cisapride has been researched along with Chronic Idiopathic Intestinal Pseudo-Obstruction in 37 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed upper gastrointestinal anatomy and function with contrast radiology and antroduodenal manometry in 51 children with chronic intestinal pseudo-obstruction (CIP) prior to entering these patients into an open-label outpatient trial of cisapride." | 9.07 | Predicting the clinical response to cisapride in children with chronic intestinal pseudo-obstruction. ( Di Lorenzo, C; Flores, AF; Garvey, TQ; Hyman, PE; McAdams, L; Tomomasa, T, 1993) |
| "In a 75-year-old man acute intestinal pseudo-obstruction was observed during treatment with baclofen 20 mg daily." | 7.69 | [Intestinal pseudo-obstruction during use of baclofen]. ( Ottervanger, JP; Schutter, N; Verhaar, HJ, 1995) |
| "Cisapride has been used in the treatment of chronic intestinal pseudo-obstruction with some success; however, the use of cisapride in the treatment of acute pseudo-obstruction has not been adequately studied." | 7.69 | Cisapride as a successful treatment for acute intestinal pseudo-obstruction. ( Barnes, JB; Lee, M; Mazloum, BW, 1996) |
| "In summary, in children with chronic intestinal pseudoobstruction, cisapride increased postprandial duodenal motility but did not improve gastric emptying." | 6.67 | Cisapride in children with chronic intestinal pseudoobstruction. An acute, double-blind, crossover, placebo-controlled trial. ( Di Lorenzo, C; Hyman, PE; Martin, S; Mena, I; Reddy, SN; Villanueva-Meyer, J, 1991) |
| ", was not greater than that of placebo, and dose-response as well as longer term trials are necessary to determine the clinical efficacy of this medication." | 6.66 | Effect of six weeks of treatment with cisapride in gastroparesis and intestinal pseudoobstruction. ( Abell, TL; Brown, ML; Camilleri, M; Hench, V; Malagelada, JR; Zinsmeister, AR, 1989) |
| "Treatment with cisapride substantially improved the patient's symptoms and improved feeding tolerance." | 5.39 | Clinical recovery of chronic intestinal pseudo-obstruction with cisapride in a complex pediatric patient. ( Boland, M; Cameron, JC; Lariviere, D; Major-Cook, N; Vaillancourt, R; Zucker, M, 2013) |
| "A case of chronic intestinal pseudoobstruction secondary to systemic amyloidosis in a patient with multiple myeloma is described." | 5.28 | Intestinal pseudoobstruction secondary to amyloidosis responsive to cisapride. ( Arthur, JF; Fraser, AG; Hamilton, I, 1991) |
| "Cisapride was effective in reducing the delayed intestinal transit time to within the normal range (delta solids = -115 +/- 25 min; delta liquids = -146 +/- 71 min; p less than 0." | 5.27 | Impaired transit of chyme in chronic intestinal pseudoobstruction. Correction by cisapride. ( Brown, ML; Camilleri, M; Malagelada, JR, 1986) |
| "We assessed upper gastrointestinal anatomy and function with contrast radiology and antroduodenal manometry in 51 children with chronic intestinal pseudo-obstruction (CIP) prior to entering these patients into an open-label outpatient trial of cisapride." | 5.07 | Predicting the clinical response to cisapride in children with chronic intestinal pseudo-obstruction. ( Di Lorenzo, C; Flores, AF; Garvey, TQ; Hyman, PE; McAdams, L; Tomomasa, T, 1993) |
| "We conducted a 12-month trial of cisapride (10 mg three times a day) in 21 patients with gastric stasis due to clinically and manometrically diagnosed gastroparesis (N = 9; seven due to diabetes) or chronic intestinal pseudo-obstruction (N = 12)." | 5.07 | Long-term efficacy of oral cisapride in symptomatic upper gut dysmotility. ( Abell, TL; Camilleri, M; DiMagno, EP; Hench, VS; Malagelada, JR; Zinsmeister, AR, 1991) |
| "This paper provides a comprehensive review of the current knowledge on cisapride in different clinical conditions in children: different manifestations of gastro-oesophageal reflux, such as (excessive) regurgitation, oesophagitis, chronic respiratory disease or uncontrolled asthma, cystic fibrosis, chronic dyspepsia, constipation and pseudo-obstruction, and as an aid to small bowel capsule-biopsy." | 4.80 | Clinical use of cisapride and its risk-benefit in paediatric patients. ( Vandenplas, Y, 1998) |
| "In a 75-year-old man acute intestinal pseudo-obstruction was observed during treatment with baclofen 20 mg daily." | 3.69 | [Intestinal pseudo-obstruction during use of baclofen]. ( Ottervanger, JP; Schutter, N; Verhaar, HJ, 1995) |
| "Cisapride has been used in the treatment of chronic intestinal pseudo-obstruction with some success; however, the use of cisapride in the treatment of acute pseudo-obstruction has not been adequately studied." | 3.69 | Cisapride as a successful treatment for acute intestinal pseudo-obstruction. ( Barnes, JB; Lee, M; Mazloum, BW, 1996) |
| "In summary, in children with chronic intestinal pseudoobstruction, cisapride increased postprandial duodenal motility but did not improve gastric emptying." | 2.67 | Cisapride in children with chronic intestinal pseudoobstruction. An acute, double-blind, crossover, placebo-controlled trial. ( Di Lorenzo, C; Hyman, PE; Martin, S; Mena, I; Reddy, SN; Villanueva-Meyer, J, 1991) |
| ", was not greater than that of placebo, and dose-response as well as longer term trials are necessary to determine the clinical efficacy of this medication." | 2.66 | Effect of six weeks of treatment with cisapride in gastroparesis and intestinal pseudoobstruction. ( Abell, TL; Brown, ML; Camilleri, M; Hench, V; Malagelada, JR; Zinsmeister, AR, 1989) |
| "Visceral myopathy is one of the causes of chronic intestinal pseudo-obstruction." | 2.52 | Abnormal layering of muscularis propria as a cause of chronic intestinal pseudo-obstruction: A case report and literature review. ( Angkathunyakul, N; Molagool, S; Ruangwattanapaisarn, N; Treepongkaruna, S, 2015) |
| "Treatment with cisapride substantially improved the patient's symptoms and improved feeding tolerance." | 1.39 | Clinical recovery of chronic intestinal pseudo-obstruction with cisapride in a complex pediatric patient. ( Boland, M; Cameron, JC; Lariviere, D; Major-Cook, N; Vaillancourt, R; Zucker, M, 2013) |
| "Cisapride was maintained for 10 days and mechanical ventilation for 30 days." | 1.29 | [Treatment of acute colonic pseudoobstruction (Ogilvie's syndrome) by cisapride]. ( Baechle, JP; Le Manach, Y; Pitti, R; Tordjmann, T, 1994) |
| "We report two cases of intestinal pseudoobstruction caused by visceral smooth muscle involvement due to myotonic muscular dystrophy." | 1.29 | Intestinal pseudoobstruction as a feature of myotonic muscular dystrophy. ( Barnert, J; Füger, K; Höpfner, W; Wienbeck, M, 1995) |
| "A case of chronic intestinal pseudoobstruction secondary to systemic amyloidosis in a patient with multiple myeloma is described." | 1.28 | Intestinal pseudoobstruction secondary to amyloidosis responsive to cisapride. ( Arthur, JF; Fraser, AG; Hamilton, I, 1991) |
| "Cisapride was effective in reducing the delayed intestinal transit time to within the normal range (delta solids = -115 +/- 25 min; delta liquids = -146 +/- 71 min; p less than 0." | 1.27 | Impaired transit of chyme in chronic intestinal pseudoobstruction. Correction by cisapride. ( Brown, ML; Camilleri, M; Malagelada, JR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (24.32) | 18.7374 |
| 1990's | 22 (59.46) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 2 (5.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angkathunyakul, N | 1 |
| Treepongkaruna, S | 1 |
| Molagool, S | 1 |
| Ruangwattanapaisarn, N | 1 |
| Shim, LS | 1 |
| Eslick, GD | 1 |
| Kan, AE | 1 |
| Kalantar, JS | 1 |
| Cameron, JC | 1 |
| Vaillancourt, R | 1 |
| Major-Cook, N | 1 |
| Boland, M | 1 |
| Zucker, M | 1 |
| Lariviere, D | 1 |
| Silk, DB | 1 |
| Bassotti, G | 1 |
| Sietchiping-Nzepa, F | 1 |
| de Roberto, G | 1 |
| Castellani, D | 1 |
| Morelli, A | 1 |
| Muñoz, MT | 1 |
| Solís Herruzo, JA | 1 |
| Schutter, N | 1 |
| Verhaar, HJ | 1 |
| Ottervanger, JP | 1 |
| Baechle, JP | 1 |
| Le Manach, Y | 1 |
| Pitti, R | 1 |
| Tordjmann, T | 1 |
| Rudolph, CD | 1 |
| Glassman, MS | 1 |
| Hyman, PE | 3 |
| Di Lorenzo, C | 2 |
| McAdams, L | 1 |
| Flores, AF | 1 |
| Tomomasa, T | 2 |
| Garvey, TQ | 1 |
| Füger, K | 1 |
| Barnert, J | 1 |
| Höpfner, W | 1 |
| Wienbeck, M | 1 |
| Mazloum, BW | 1 |
| Barnes, JB | 1 |
| Lee, M | 1 |
| Cucchiara, S | 1 |
| Yanagisawa, M | 1 |
| Kusano, M | 1 |
| Doi, I | 1 |
| Motegi, K | 1 |
| Nakamura, K | 1 |
| Kawamura, O | 1 |
| Mori, M | 1 |
| Sekiguchi, T | 1 |
| Vandenplas, Y | 1 |
| Torii, A | 1 |
| Stanghellini, V | 1 |
| Corinaldesi, R | 1 |
| Ghidini, C | 1 |
| Ricci Maccarini, M | 1 |
| De Giorgio, R | 1 |
| Biasco, G | 1 |
| Brillanti, S | 1 |
| Paparo, GF | 1 |
| Barbara, L | 1 |
| Casasa, JM | 1 |
| Tollesson, PO | 1 |
| Cassuto, J | 1 |
| Rimbäck, G | 1 |
| Faxén, A | 1 |
| Bergman, L | 1 |
| Mattsson, E | 1 |
| Reddy, SN | 1 |
| Villanueva-Meyer, J | 1 |
| Mena, I | 1 |
| Martin, S | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Fraser, AG | 1 |
| Arthur, JF | 1 |
| Hamilton, I | 1 |
| Abell, TL | 2 |
| Camilleri, M | 3 |
| DiMagno, EP | 1 |
| Hench, VS | 1 |
| Zinsmeister, AR | 2 |
| Malagelada, JR | 3 |
| Reyntjens, A | 1 |
| Verlinden, M | 1 |
| Schuermans, V | 1 |
| Pelckmans, PA | 1 |
| Michielsen, PP | 1 |
| Jorens, PG | 1 |
| Van Maercke, YM | 1 |
| MacColl, C | 1 |
| MacCannell, KL | 1 |
| Baylis, B | 1 |
| Lee, SS | 1 |
| Demling, L | 1 |
| Brown, ML | 2 |
| Hench, V | 1 |
| Fraitag, B | 1 |
| Cloarec, D | 1 |
| Galmiche, JP | 1 |
| Graham, JR | 1 |
| Sparnon, AL | 1 |
| Spitz, L | 1 |
| Ricci, DA | 1 |
| McCallum, RW | 1 |
| Cohen, NP | 1 |
| Booth, IW | 1 |
| Parashar, K | 1 |
| Corkery, JJ | 1 |
| McDiarmid, SV | 1 |
| Napolitano, J | 1 |
| Abrams, CE | 1 |
| von Ritter, C | 1 |
| Hunter, S | 1 |
| Hinder, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery[NCT02056405] | Phase 4 | 90 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for cisapride and Chronic Idiopathic Intestinal Pseudo-Obstruction
| Article | Year |
|---|---|
Abnormal layering of muscularis propria as a cause of chronic intestinal pseudo-obstruction: A case report and literature review.
Topics: Biomarkers; Biopsy; Brachydactyly; Chronic Disease; Cisapride; Digestive System Abnormalities; Enter | 2015 |
[Chronic intestinal pseudo-obstruction].
Topics: Chronic Disease; Cisapride; Dietary Supplements; Endoscopy; Gastrointestinal Agents; Humans; Intesti | 2007 |
Cisapride therapy for gastrointestinal disease.
Topics: Adult; Animals; Child; Cisapride; Constipation; Esophageal Motility Disorders; Gastrointestinal Dise | 1996 |
Clinical use of cisapride and its risk-benefit in paediatric patients.
Topics: Child; Child, Preschool; Cisapride; Constipation; Cystic Fibrosis; Drug Interactions; Dyspepsia; Fec | 1998 |
Cisapride in the treatment of chronic intestinal pseudo-obstruction.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cisapride; Female; Gastrointestinal Motility; Huma | 1990 |
[Cisapride: pharmacology, current therapeutic results and future prospects].
Topics: Cisapride; Constipation; Dyspepsia; Esophagitis; Esophagus; Forecasting; Gastric Emptying; Gastroeso | 1989 |
Diagnosis and treatment of delayed gastric emptying.
Topics: Anemia, Pernicious; Anorexia Nervosa; Cisapride; Connective Tissue Diseases; Diabetes Complications; | 1988 |
8 trials available for cisapride and Chronic Idiopathic Intestinal Pseudo-Obstruction
| Article | Year |
|---|---|
Predicting the clinical response to cisapride in children with chronic intestinal pseudo-obstruction.
Topics: Child, Preschool; Chronic Disease; Cisapride; Enteral Nutrition; Female; Humans; Intestinal Pseudo-O | 1993 |
Treatment of postoperative paralytic ileus with cisapride.
Topics: Cholecystectomy; Cisapride; Colonic Diseases; Double-Blind Method; Female; Gastrointestinal Motility | 1991 |
Cisapride in children with chronic intestinal pseudoobstruction. An acute, double-blind, crossover, placebo-controlled trial.
Topics: Child; Child, Preschool; Cisapride; Double-Blind Method; Duodenum; Eating; Female; Gastric Emptying; | 1991 |
Long-term efficacy of oral cisapride in symptomatic upper gut dysmotility.
Topics: Administration, Oral; Adult; Body Weight; Chronic Disease; Cisapride; Double-Blind Method; Female; G | 1991 |
[Treatment of chronic-obstructive upper abdominal complaints. Outlook. Further hypothetical indications].
Topics: Cisapride; Clinical Trials as Topic; Constipation; Dyspepsia; Gastroesophageal Reflux; Gastrointesti | 1990 |
Cisapride in the treatment of chronic intestinal pseudo-obstruction.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cisapride; Female; Gastrointestinal Motility; Huma | 1990 |
Effect of six weeks of treatment with cisapride in gastroparesis and intestinal pseudoobstruction.
Topics: Adult; Cisapride; Clinical Trials as Topic; Double-Blind Method; Female; Gastric Emptying; Gastroint | 1989 |
Cisapride does not reduce postoperative paralytic ileus.
Topics: Cisapride; Clinical Trials as Topic; Double-Blind Method; Humans; Intestinal Pseudo-Obstruction; Pip | 1987 |
23 other studies available for cisapride and Chronic Idiopathic Intestinal Pseudo-Obstruction
| Article | Year |
|---|---|
A case of chronic intestinal pseudo-obstruction secondary to primary visceral myopathy.
Topics: Adolescent; Biopsy; Chronic Disease; Cisapride; Female; Gastrointestinal Agents; Humans; Indoles; In | 2008 |
Clinical recovery of chronic intestinal pseudo-obstruction with cisapride in a complex pediatric patient.
Topics: Antacids; Antiemetics; Child; Cisapride; Domperidone; Gastrointestinal Agents; Gastrointestinal Moti | 2013 |
Pseudo-pseudo-obstruction: lessons in diagnosis and management.
Topics: Chronic Disease; Cisapride; Diagnosis, Differential; Gastrointestinal Agents; Humans; Intestinal Pse | 2004 |
Pseudo-pseudo-obstruction.
Topics: Abdominal Pain; Chronic Disease; Cisapride; Diagnosis, Differential; Female; Gastrointestinal Agents | 2004 |
[Intestinal pseudo-obstruction during use of baclofen].
Topics: Aged; Anti-Ulcer Agents; Baclofen; Bisacodyl; Cathartics; Cisapride; Humans; Intestinal Pseudo-Obstr | 1995 |
[Treatment of acute colonic pseudoobstruction (Ogilvie's syndrome) by cisapride].
Topics: Aged; Cisapride; Colonic Diseases; Colonoscopy; Female; Gastrointestinal Motility; Humans; Intestina | 1994 |
Diagnosis of pseudo-obstruction in children.
Topics: Child; Chronic Disease; Cisapride; Electromyography; Gastrointestinal Motility; Gastrointestinal Tra | 1993 |
Intestinal pseudoobstruction as a feature of myotonic muscular dystrophy.
Topics: Cathartics; Cisapride; Female; Follow-Up Studies; Humans; Intestinal Pseudo-Obstruction; Male; Manom | 1995 |
Cisapride as a successful treatment for acute intestinal pseudo-obstruction.
Topics: Acute Disease; Cisapride; Colonic Diseases; Fatal Outcome; Humans; Intestinal Pseudo-Obstruction; Ma | 1996 |
[Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)].
Topics: Aged; Chronic Disease; Cisapride; Drug Therapy, Combination; Erythromycin; Female; Gastrointestinal | 1998 |
[Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)].
Topics: Chronic Disease; Cisapride; Drug Therapy, Combination; Erythromycin; Gastrointestinal Agents; Humans | 1999 |
Reversibility of gastrointestinal motor abnormalities in chronic intestinal pseudo-obstruction.
Topics: Adult; Chronic Disease; Cisapride; Fasting; Gastrointestinal Motility; Humans; Intestinal Pseudo-Obs | 1992 |
[The treatment of intestinal pseudo-obstruction].
Topics: Cisapride; Colonic Diseases; Combined Modality Therapy; Hirschsprung Disease; Humans; Ileostomy; Inf | 1991 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Intestinal pseudoobstruction secondary to amyloidosis responsive to cisapride.
Topics: Amyloidosis; Cisapride; Female; Humans; Intestinal Diseases; Intestinal Pseudo-Obstruction; Middle A | 1991 |
Cisapride in Ogilvie's syndrome.
Topics: Aged; Cisapride; Colonic Pseudo-Obstruction; Female; Humans; Intestinal Pseudo-Obstruction; Male; Pi | 1990 |
Treatment of acute colonic pseudoobstruction (Ogilvie's syndrome) with cisapride.
Topics: Acute Disease; Aged; Cisapride; Colonic Diseases; Colonic Pseudo-Obstruction; Drug Evaluation; Drugs | 1990 |
[The typical patient with disorder of digestive motility].
Topics: Cisapride; Dyspepsia; Gastric Emptying; Gastroesophageal Reflux; Humans; Intestinal Pseudo-Obstructi | 1990 |
Cisapride for severe non-ulcer dyspepsia, pseudoobstruction and constipation.
Topics: Adult; Aged; Cisapride; Constipation; Dyspepsia; Female; Humans; Intestinal Pseudo-Obstruction; Male | 1989 |
Pharmacological manipulation of postoperative intestinal adhesions.
Topics: Animals; Cisapride; Female; Gastrointestinal Motility; Intestinal Diseases; Intestinal Pseudo-Obstru | 1989 |
Successful management of idiopathic intestinal pseudo-obstruction with cisapride.
Topics: Administration, Rectal; Child; Chronic Disease; Cisapride; Humans; Injections, Intravenous; Intestin | 1988 |
Antroduodenal motility in children with chronic intestinal pseudo-obstruction.
Topics: Child; Child, Preschool; Cisapride; Duodenum; Female; Gastrointestinal Motility; Humans; Infant; Int | 1988 |
Impaired transit of chyme in chronic intestinal pseudoobstruction. Correction by cisapride.
Topics: Adult; Cisapride; Eating; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Intestinal Ob | 1986 |