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cisapride and Cerebral Palsy

cisapride has been researched along with Cerebral Palsy in 3 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"Cisapride was used to treat gastro-oesophageal reflux in seven children with neurodevelopmental disorders and in 15 children who were neurologically normal."7.68The effects of cisapride on gastro-oesophageal reflux in children with and without neurological disorders. ( Brueton, MJ; Clarke, GS; Sandhu, BK, 1990)
"Cisapride treatment was assigned to the patients with pathologic monitoring results at a dose of 0."5.32Gastroesophageal reflux in children with cerebral palsy: efficacy of cisapride. ( Aydogdu, S; Bozkurt, M; Serdaroglu, G; Tekgul, H; Tutuncuoglu, S, 2004)
"Cisapride was used to treat gastro-oesophageal reflux in seven children with neurodevelopmental disorders and in 15 children who were neurologically normal."3.68The effects of cisapride on gastro-oesophageal reflux in children with and without neurological disorders. ( Brueton, MJ; Clarke, GS; Sandhu, BK, 1990)
"We hypothesised that gastro-oesophageal reflux (GOR) may exacerbate drooling by stimulation of the oesophago-salivary reflex."2.68Effect of antireflux medication on salivary drooling in children with cerebral palsy. ( Catto-Smith, AG; Heine, RG; Reddihough, DS, 1996)
"Cisapride treatment was assigned to the patients with pathologic monitoring results at a dose of 0."1.32Gastroesophageal reflux in children with cerebral palsy: efficacy of cisapride. ( Aydogdu, S; Bozkurt, M; Serdaroglu, G; Tekgul, H; Tutuncuoglu, S, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bozkurt, M1
Tutuncuoglu, S1
Serdaroglu, G1
Tekgul, H1
Aydogdu, S1
Heine, RG1
Catto-Smith, AG1
Reddihough, DS1
Brueton, MJ1
Clarke, GS1
Sandhu, BK1

Trials

1 trial available for cisapride and Cerebral Palsy

ArticleYear
Effect of antireflux medication on salivary drooling in children with cerebral palsy.
    Developmental medicine and child neurology, 1996, Volume: 38, Issue:11

    Topics: Adolescent; Cerebral Palsy; Child; Child, Preschool; Cisapride; Esophagus; Female; Gastroesophageal

1996

Other Studies

2 other studies available for cisapride and Cerebral Palsy

ArticleYear
Gastroesophageal reflux in children with cerebral palsy: efficacy of cisapride.
    Journal of child neurology, 2004, Volume: 19, Issue:12

    Topics: Cerebral Palsy; Child; Child, Preschool; Cisapride; Female; Follow-Up Studies; Gastric Acidity Deter

2004
The effects of cisapride on gastro-oesophageal reflux in children with and without neurological disorders.
    Developmental medicine and child neurology, 1990, Volume: 32, Issue:7

    Topics: Acetylcholine; Brain Damage, Chronic; Cerebral Palsy; Child; Child, Preschool; Cisapride; Down Syndr

1990