Page last updated: 2024-10-25

cisapride and Central Nervous System Diseases

cisapride has been researched along with Central Nervous System Diseases in 4 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
"Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease."4.90Management of faecal incontinence and constipation in adults with central neurological diseases. ( Cody, JD; Coggrave, M; Norton, C, 2014)
"Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease."4.89Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C, 2013)
" Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (three trials)."4.83Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C; Wiesel, PH, 2006)
" Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (two trials)."4.81Management of faecal incontinence and constipation in adults with central neurological diseases. ( Brazzelli, M; Norton, C; Wiesel, PH, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coggrave, M3
Norton, C4
Cody, JD1
Wiesel, PH2
Brazzelli, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neurogenic Bowel Dysfunction: Evaluation of the Effects of Osteopathic Manipulative Treatment in People With Central Nervous System Injury[NCT04127617]70 participants (Anticipated)Interventional2019-10-28Recruiting
Automatic Colon-specific Massage With MOWOOT Medical Device to Treat Chronic Constipation in Adults[NCT04262752]100 participants (Actual)Interventional2018-01-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for cisapride and Central Nervous System Diseases

ArticleYear
Management of faecal incontinence and constipation in adults with central neurological diseases.
    The Cochrane database of systematic reviews, 2013, Dec-18, Issue:12

    Topics: Adult; Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestina

2013
Management of faecal incontinence and constipation in adults with central neurological diseases.
    The Cochrane database of systematic reviews, 2014, Jan-13, Issue:1

    Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent

2014
Management of faecal incontinence and constipation in adults with central neurological diseases.
    The Cochrane database of systematic reviews, 2006, Apr-19, Issue:2

    Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent

2006
Management of faecal incontinence and constipation in adults with central neurological diseases.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent

2001