Page last updated: 2024-10-25

cisapride and Cardiovascular Diseases

cisapride has been researched along with Cardiovascular Diseases in 2 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"The nonselective 5-HT(4) receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs)."2.48Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. ( Camilleri, M; Chang, L; Chey, WD; De Maeyer, JH; Galligan, JJ; Lacy, BE; Müller-Lissner, S; Quigley, EM; Schuurkes, J; Stanghellini, V; Tack, J, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tack, J1
Camilleri, M1
Chang, L1
Chey, WD1
Galligan, JJ1
Lacy, BE1
Müller-Lissner, S1
Quigley, EM1
Schuurkes, J1
De Maeyer, JH1
Stanghellini, V1
Francis, GS1

Reviews

2 reviews available for cisapride and Cardiovascular Diseases

ArticleYear
Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:7

    Topics: Cardiovascular Diseases; Cisapride; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Indo

2012
Cardiac complications in the intensive care unit.
    Clinics in chest medicine, 1999, Volume: 20, Issue:2

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiovascular Diseases; Cisapride; Electrocardiography; Erythr

1999