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cisapride and Cardiac Diseases

cisapride has been researched along with Cardiac Diseases in 4 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
"Although the new second-generation nonsedative antihistamines terfenadine and astemizole were launched as highly selective and specific H(1)-receptor antagonists, they were later found to cause prolongation of the QT-interval and severe cardiac arrhythmias."4.81Cardiotoxicity of new antihistamines and cisapride. ( Paakkari, I, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gau, CS1
Chang, IS1
Lin Wu, FL1
Yu, HT1
Huang, YW1
Chi, CL1
Chien, SY1
Lin, KM1
Liu, MY1
Wang, HP1
Autret, E1
Jonville-Bera, AP1
Champel, V1
Veldhuyzen van Zanten, SJ1
Flook, N1
Chiba, N1
Armstrong, D1
Barkun, A1
Bradette, M1
Thomson, A1
Bursey, F1
Blackshaw, P1
Frail, D1
Sinclair, P1
Paakkari, I1

Reviews

1 review available for cisapride and Cardiac Diseases

ArticleYear
Cardiotoxicity of new antihistamines and cisapride.
    Toxicology letters, 2002, Feb-28, Volume: 127, Issue:1-3

    Topics: Arrhythmias, Cardiac; Astemizole; Benzimidazoles; Butyrophenones; Cetirizine; Cisapride; Heart Disea

2002

Other Studies

3 other studies available for cisapride and Cardiac Diseases

ArticleYear
Usage of the claim database of national health insurance programme for analysis of cisapride-erythromycin co-medication in Taiwan.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cisapride; Databases, Factual; Dose-Response Relat

2007
[Cardiac poisoning of cisapride (Prepulsid) must be considered in its prescription, specially in premature infants].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1997, Volume: 4, Issue:6

    Topics: Anti-Ulcer Agents; Child; Cisapride; Drug Prescriptions; Heart Diseases; Humans; Infant; Infant, New

1997
Update from the Canadian Dyspepsia Working Group.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2000, Sep-19, Volume: 163, Issue:6

    Topics: Canada; Cisapride; Dyspepsia; Gastroesophageal Reflux; Gastrointestinal Agents; Heart Diseases; Huma

2000