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cisapride and Bradycardia

cisapride has been researched along with Bradycardia in 4 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
"A 2-month-old infant with gastroesophageal reflux was treated with cisapride."3.69Cisapride-induced long QT interval. ( Bryant, RM; Fenrich, AL; Grifka, RG; Lewin, MB, 1996)
"Drugs can cause cardiac arrhythmias in a number of clinical situations, and many of the implicated agents are used to treat non-cardiac conditions."2.40Drug-induced cardiac arrhythmias: incidence, prevention and management. ( Doig, JC, 1997)
"We studied subjects with gastroesophageal reflux disease (apparent life-threatening events, apneas, bradycardias) before and 3 days after starting cisapride (0."1.3224-hour electrocardiogram before and during cisapride treatment in neonates and infants. ( Belli, DC; Friedli, B; Jaeggi, E; Zamora, SA, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becker, DP1
Flynn, DL1
Moormann, AE1
Nosal, R1
Villamil, CI1
Loeffler, R1
Gullikson, GW1
Moummi, C1
Yang, DC1
Zamora, SA1
Belli, DC1
Friedli, B1
Jaeggi, E1
Lewin, MB1
Bryant, RM1
Fenrich, AL1
Grifka, RG1
Doig, JC1

Reviews

1 review available for cisapride and Bradycardia

ArticleYear
Drug-induced cardiac arrhythmias: incidence, prevention and management.
    Drug safety, 1997, Volume: 17, Issue:4

    Topics: Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-Infective Agents;

1997

Other Studies

3 other studies available for cisapride and Bradycardia

ArticleYear
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
    Journal of medicinal chemistry, 2006, Feb-09, Volume: 49, Issue:3

    Topics: Amides; Animals; Benzamides; Bradycardia; Brain; Dogs; Esophagus; Esters; Female; Gastric Emptying;

2006
24-hour electrocardiogram before and during cisapride treatment in neonates and infants.
    Biology of the neonate, 2004, Volume: 85, Issue:4

    Topics: Arrhythmias, Cardiac; Bradycardia; Cisapride; Electrocardiography; Gastroesophageal Reflux; Gestatio

2004
Cisapride-induced long QT interval.
    The Journal of pediatrics, 1996, Volume: 128, Issue:2

    Topics: Adult; Age Factors; Bradycardia; Cisapride; Electrocardiography; Female; Gastroesophageal Reflux; Hu

1996