cisapride has been researched along with Barrett Esophagus in 6 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Barrett Esophagus: A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to look at duodenal reflux in the oesophagus together with motility characteristics in a group of patients with Barrett's oesophagus and compare them with a mild oesophagitis group and to assess the effect of cisapride on any abnormalities." | 9.08 | Effect of cisapride on oesophageal motility and duodenogastro-oesophageal reflux in patients with Barrett's oesophagus. ( Bird, NC; Globe, J; Johnson, AG; Smythe, A; Troy, GP, 1997) |
| " The aim of this study was to look at duodenal reflux in the oesophagus together with motility characteristics in a group of patients with Barrett's oesophagus and compare them with a mild oesophagitis group and to assess the effect of cisapride on any abnormalities." | 5.08 | Effect of cisapride on oesophageal motility and duodenogastro-oesophageal reflux in patients with Barrett's oesophagus. ( Bird, NC; Globe, J; Johnson, AG; Smythe, A; Troy, GP, 1997) |
| "Barrett's esophagus has to be regarded as a precancerous lesion, therefore surveillance strategy is required." | 2.43 | [Gastroesophageal reflux disease]. ( Gräter, H, 2005) |
| "Gastroesophageal reflux (GER) occurs in 2 distinct forms that differ in pathophysiology, clinical presentation, natural history, and therapy: mild GER (with no or minimal esophagitis) and classic, severe reflux (at risk for erosive esophagitis)." | 2.40 | Gastroesophageal reflux: practical management of a common, challenging disorder. ( Fass, R; Soll, AH, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smythe, A | 2 |
| Bird, NC | 2 |
| Troy, GP | 2 |
| Ackroyd, R | 1 |
| Johnson, AG | 2 |
| Gräter, H | 1 |
| McDougall, NI | 1 |
| Johnston, BT | 1 |
| Kee, F | 1 |
| Collins, JS | 1 |
| McFarland, RJ | 1 |
| Love, AH | 1 |
| Globe, J | 1 |
| Heading, RC | 1 |
| Baldi, F | 1 |
| Holloway, RH | 1 |
| Janssens, J | 1 |
| Jian, R | 1 |
| McCallum, RW | 1 |
| Richter, JE | 1 |
| Scarpignato, C | 1 |
| Sontag, SJ | 1 |
| Wienbeck, M | 1 |
| Soll, AH | 1 |
| Fass, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404] | 98 participants (Actual) | Interventional | 2009-03-01 | Completed | |||
| Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study[NCT01574573] | 52 participants (Actual) | Interventional | 2009-06-30 | Terminated (stopped due to Closed due to lack of recruitment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cisapride and Barrett Esophagus
| Article | Year |
|---|---|
[Gastroesophageal reflux disease].
Topics: Aged; Antacids; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cisapride; Diagnosis, Differential; En | 2005 |
Gastroesophageal reflux: practical management of a common, challenging disorder.
Topics: Anti-Ulcer Agents; Barrett Esophagus; Cisapride; Endoscopy, Gastrointestinal; Gastrins; Gastroesopha | 1999 |
2 trials available for cisapride and Barrett Esophagus
| Article | Year |
|---|---|
Does the addition of a prokinetic to proton pump inhibitor therapy help reduce duodenogastro-oesophageal reflux in patients with Barrett's oesophagus?
Topics: Adult; Aged; Anti-Ulcer Agents; Barrett Esophagus; Cisapride; Double-Blind Method; Drug Therapy, Com | 2003 |
Effect of cisapride on oesophageal motility and duodenogastro-oesophageal reflux in patients with Barrett's oesophagus.
Topics: Adult; Aged; Barrett Esophagus; Bile Acids and Salts; Cisapride; Duodenogastric Reflux; Electrodes; | 1997 |
2 other studies available for cisapride and Barrett Esophagus
| Article | Year |
|---|---|
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea | 1996 |
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea | 1996 |
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea | 1996 |
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea | 1996 |
Prokinetics in the treatment of gastro-oesophageal reflux disease. International symposium. Paris, France, 5 September 1996.
Topics: Barrett Esophagus; Bethanechol; Cisapride; Gastric Emptying; Gastroesophageal Reflux; Gastrointestin | 1998 |