cisapride has been researched along with Autoimmune Diabetes in 21 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether cisapride accelerates gastric emptying in the long term or improves diabetes control in patients with diabetic gastroparesis." | 9.10 | Long-term cisapride treatment improves diabetic gastroparesis but not glycaemic control. ( Braden, B; Caspary, WF; Enghofer, M; Lembcke, B; Schaub, M; Usadel, KH, 2002) |
| " The aim of this study was to determine in patients with diabetic gastroparesis whether the effect of cisapride on gastric emptying of solids and liquids is influenced by the plasma glucose concentration." | 9.10 | Relationship between the effects of cisapride on gastric emptying and plasma glucose concentrations in diabetic gastroparesis. ( Harding, PE; Horowitz, M; Jones, KL; Wishart, JM, 2002) |
| "To assess the effect of an 8-week course of domperidone or cisapride on gastric electrical activity, gastric emptying time and dyspeptic symptoms in children with insulin-dependent diabetes mellitus and gastroparesis." | 9.10 | Domperidone is more effective than cisapride in children with diabetic gastroparesis. ( Borrelli, O; Corrado, G; Cucchiara, S; Di Nardo, G; Dito, L; Franzese, A; Grandinetti, AL; Rea, P, 2002) |
| "Erythromycin, a macrolide antibiotic, has been shown to have gastric prokinetic effects and has been proposed as an alternative therapeutic option for diabetic gastroparesis." | 7.69 | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. ( Andriulli, A; Annese, V; Bassotti, G; Frusciante, V; Germani, U; Lombardi, G, 1997) |
| " Chronic administration of a prokinetic drug resulted in improved solid gastric emptying (percentage residual) at 120 min (p=0." | 6.71 | Glucose control is not improved by accelerating gastric emptying in patients with type 1 diabetes mellitus and gastroparesis. a pilot study with cisapride as a model drug. ( Feinle, C; Fried, M; Honegger, RA; Lehmann, R; Schwizer, W; Spinas, GA, 2003) |
| "To investigate whether cisapride accelerates gastric emptying in the long term or improves diabetes control in patients with diabetic gastroparesis." | 5.10 | Long-term cisapride treatment improves diabetic gastroparesis but not glycaemic control. ( Braden, B; Caspary, WF; Enghofer, M; Lembcke, B; Schaub, M; Usadel, KH, 2002) |
| " The aim of this study was to determine in patients with diabetic gastroparesis whether the effect of cisapride on gastric emptying of solids and liquids is influenced by the plasma glucose concentration." | 5.10 | Relationship between the effects of cisapride on gastric emptying and plasma glucose concentrations in diabetic gastroparesis. ( Harding, PE; Horowitz, M; Jones, KL; Wishart, JM, 2002) |
| "To assess the effect of an 8-week course of domperidone or cisapride on gastric electrical activity, gastric emptying time and dyspeptic symptoms in children with insulin-dependent diabetes mellitus and gastroparesis." | 5.10 | Domperidone is more effective than cisapride in children with diabetic gastroparesis. ( Borrelli, O; Corrado, G; Cucchiara, S; Di Nardo, G; Dito, L; Franzese, A; Grandinetti, AL; Rea, P, 2002) |
| "Erythromycin, a macrolide antibiotic, has been shown to have gastric prokinetic effects and has been proposed as an alternative therapeutic option for diabetic gastroparesis." | 3.69 | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. ( Andriulli, A; Annese, V; Bassotti, G; Frusciante, V; Germani, U; Lombardi, G, 1997) |
| " Chronic administration of a prokinetic drug resulted in improved solid gastric emptying (percentage residual) at 120 min (p=0." | 2.71 | Glucose control is not improved by accelerating gastric emptying in patients with type 1 diabetes mellitus and gastroparesis. a pilot study with cisapride as a model drug. ( Feinle, C; Fried, M; Honegger, RA; Lehmann, R; Schwizer, W; Spinas, GA, 2003) |
| "At baseline conditions IDDM and PSS patients exhibited reduced gastric peristalsis and delayed emptying compared to controls." | 2.71 | Prokinetic therapy: what can be measured by gastric scintigraphy? ( Folwaczny, C; Linke, R; Meier, M; Muenzing, W; Schnell, O; Tatsch, K, 2005) |
| " These results indicate that single-dose cisapride increases esophageal emptying in insulin-dependent diabetics and that chronic administration of cisapride is effective in the treatment of diabetic gastroparesis." | 2.66 | Effect of cisapride on gastric and esophageal emptying in insulin-dependent diabetes mellitus. ( Chatterton, BE; Harding, PE; Horowitz, M; Maddern, GJ; Maddox, A; Shearman, DJ; Wishart, J, 1987) |
| "Vomiting was the first cause of admission in diabetics." | 1.29 | Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. ( Gallar, P; Guijo, G; Oliet, A; Ortega, O; Vigil, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braden, B | 1 |
| Enghofer, M | 1 |
| Schaub, M | 1 |
| Usadel, KH | 1 |
| Caspary, WF | 2 |
| Lembcke, B | 2 |
| Lehmann, R | 1 |
| Honegger, RA | 1 |
| Feinle, C | 1 |
| Fried, M | 1 |
| Spinas, GA | 1 |
| Schwizer, W | 1 |
| Melga, P | 1 |
| Mansi, C | 1 |
| Linke, R | 1 |
| Meier, M | 1 |
| Muenzing, W | 1 |
| Folwaczny, C | 1 |
| Schnell, O | 1 |
| Tatsch, K | 1 |
| Olausson, EA | 1 |
| Alpsten, M | 1 |
| Larsson, A | 1 |
| Mattsson, H | 1 |
| Andersson, H | 1 |
| Attvall, S | 1 |
| Rothstein, RD | 1 |
| Alavi, A | 1 |
| Reynolds, JC | 1 |
| Gallar, P | 1 |
| Oliet, A | 1 |
| Vigil, A | 1 |
| Ortega, O | 1 |
| Guijo, G | 1 |
| Kawagishi, T | 1 |
| Nishizawa, Y | 1 |
| Okuno, Y | 1 |
| Sekiya, K | 1 |
| Morii, H | 1 |
| Annese, V | 1 |
| Lombardi, G | 1 |
| Frusciante, V | 1 |
| Germani, U | 1 |
| Andriulli, A | 1 |
| Bassotti, G | 1 |
| Stacher, G | 1 |
| Schernthaner, G | 1 |
| Francesconi, M | 1 |
| Kopp, HP | 1 |
| Bergmann, H | 1 |
| Stacher-Janotta, G | 1 |
| Weber, U | 1 |
| Johansson, UB | 1 |
| Wredling, RA | 1 |
| Adamson, UC | 1 |
| Lins, PE | 1 |
| Horowitz, M | 3 |
| Jones, KL | 1 |
| Harding, PE | 2 |
| Wishart, JM | 1 |
| Franzese, A | 1 |
| Borrelli, O | 1 |
| Corrado, G | 1 |
| Rea, P | 1 |
| Di Nardo, G | 1 |
| Grandinetti, AL | 1 |
| Dito, L | 1 |
| Cucchiara, S | 1 |
| Reissell, E | 1 |
| Taskinen, MR | 1 |
| Orko, R | 1 |
| Lindgren, L | 1 |
| Wehrmann, T | 1 |
| Lazarovits, AI | 1 |
| Page, D | 1 |
| Roberts, AP | 1 |
| Brogna, A | 1 |
| Ferrara, R | 1 |
| Scornavacca, G | 1 |
| Lombardo, A | 1 |
| Bucceri, A | 1 |
| Catalano, F | 1 |
| Paradisi, V | 1 |
| Onorato, S | 1 |
| Vogelberg, KH | 1 |
| Dalügge, A | 1 |
| Havelund, T | 1 |
| Oster-Jørgensen, E | 1 |
| Eshøj, O | 1 |
| Larsen, ML | 1 |
| Lauritsen, K | 1 |
| Maddox, A | 1 |
| Maddern, GJ | 1 |
| Chatterton, BE | 1 |
| Wishart, J | 1 |
| Shearman, DJ | 1 |
14 trials available for cisapride and Autoimmune Diabetes
| Article | Year |
|---|---|
Long-term cisapride treatment improves diabetic gastroparesis but not glycaemic control.
Topics: Aged; Blood Glucose; Breath Tests; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug | 2002 |
Glucose control is not improved by accelerating gastric emptying in patients with type 1 diabetes mellitus and gastroparesis. a pilot study with cisapride as a model drug.
Topics: Adult; Age of Onset; Blood Glucose; Body Constitution; Cisapride; Diabetes Mellitus, Type 1; Diabeti | 2003 |
Type 1 (insulin-dependent) diabetes mellitus and gastric emptying: role of blood glucose concentration and dopamine D2 receptors.
Topics: Adult; Blood Glucose; Breath Tests; Cisapride; Cross-Over Studies; Diabetes Mellitus, Type 1; Female | 2004 |
Prokinetic therapy: what can be measured by gastric scintigraphy?
Topics: Adult; Aged; Cisapride; Diabetes Mellitus, Type 1; Female; Gastric Emptying; Gastrointestinal Agents | 2005 |
Effect of cisapride on gastric emptying of indigestible solids and plasma motilin concentration in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Cisapride; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1993 |
Cisapride versus placebo for 8 weeks on glycemic control and gastric emptying in insulin-dependent diabetes: a double blind cross-over trial.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Glucose; Cardiovascular System; Cisapride; Cro | 1999 |
A randomised study evaluating the effects of cisapride on glucose variability and quality of life parameters in insulin-dependent diabetes mellitus patients.
Topics: Blood Glucose; Cisapride; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Evalua | 1999 |
Relationship between the effects of cisapride on gastric emptying and plasma glucose concentrations in diabetic gastroparesis.
Topics: Adult; Blood Glucose; Cisapride; Diabetes Mellitus, Type 1; Female; Gastric Emptying; Gastrointestin | 2002 |
Domperidone is more effective than cisapride in children with diabetic gastroparesis.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Cisapride; Diabetes Mellitus, Type 1; Dom | 2002 |
Increased volume of gastric contents in diabetic patients undergoing renal transplantation: lack of effect with cisapride.
Topics: Administration, Oral; Adult; Anesthesia, General; Cisapride; Defecation; Diabetes Mellitus, Type 1; | 1992 |
Influence of cisapride on antroduodenal motor function in healthy subjects and diabetics with autonomic neuropathy.
Topics: Adult; Autonomic Nervous System Diseases; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathie | 1991 |
Cisapride and gastric emptying of a solid meal in dyspeptic diabetics without autonomic neuropathy and in healthy volunteers.
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Dyspepsia; Female; Gastric Emptying; Humans; Male; Midd | 1989 |
Effects of cisapride on gastroparesis in patients with insulin-dependent diabetes mellitus. A double-blind controlled trial.
Topics: Cisapride; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Double-Blind Method; Gastric Emptyin | 1987 |
Effect of cisapride on gastric and esophageal emptying in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Cisapride; Diabetes Mellitus, Type 1; Esophagus; Female; Gastric Emptying; Hum | 1987 |
7 other studies available for cisapride and Autoimmune Diabetes
| Article | Year |
|---|---|
Small particle size of a solid meal increases gastric emptying and late postprandial glycaemic response in diabetic subjects with gastroparesis.
Topics: Aged; Blood Glucose; Cisapride; Diabetes Mellitus, Type 1; Diet, Diabetic; Eating; Female; Gastric E | 2008 |
Electrogastrography in patients with gastroparesis and effect of long-term cisapride.
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Electromyography; Electrophysiology; Gastric Emptying; | 1993 |
Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin.
Topics: Cisapride; Diabetes Mellitus, Type 1; Erythromycin; Female; Gastric Emptying; Hospitalization; Human | 1993 |
Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Erythromycin; Female; Gastric Emptying; Gastroparesis; | 1997 |
Intraperitoneal cisapride for the treatment of diabetics with gastroparesis and end-stage renal disease.
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Drug Evaluation; Gastrointestin | 1990 |
Long-term efficacy of cisapride in diabetic gastroparesis.
Topics: Cisapride; Diabetes Mellitus, Type 1; Gastric Emptying; Humans; Male; Middle Aged; Piperidines; Sero | 1990 |
[Sonographic studies during drug treatment of diabetic gastroparesis].
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastric Emptying; Gastro | 1988 |