cisapride has been researched along with Atrial Fibrillation in 3 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objectives were to study the absorption kinetics and pharmacodynamics of two oral formulations of flecainide in patients with atrial fibrillation (AF) and to assess the relationship between pharmacokinetic parameters and the efficacy in restoring sinus rhythm." | 9.11 | Absorption kinetics and pharmacodynamics of two oral dosage forms of flecainide in patients with an episode of paroxysmal atrial fibrillation. ( Brouwers, JR; Deneer, VH; Dunselman, PH; Gossen, SA; Kingma, JH; Lie-A-Huen, L; Proost, JH; Stuurman, A; Uytdehaag, GM, 2004) |
| "The objectives were to study the absorption kinetics and pharmacodynamics of two oral formulations of flecainide in patients with atrial fibrillation (AF) and to assess the relationship between pharmacokinetic parameters and the efficacy in restoring sinus rhythm." | 5.11 | Absorption kinetics and pharmacodynamics of two oral dosage forms of flecainide in patients with an episode of paroxysmal atrial fibrillation. ( Brouwers, JR; Deneer, VH; Dunselman, PH; Gossen, SA; Kingma, JH; Lie-A-Huen, L; Proost, JH; Stuurman, A; Uytdehaag, GM, 2004) |
| " Therefore, the effects of a novel 5-HT(4) receptor antagonist, RS-100302, and the partial agonist cisapride on atrial flutter and fibrillation induced in swine were studied to delineate the role of the 5-HT(4) receptor in modulating atrial electrophysiological properties and the antiarrhythmic potential of RS-100302." | 3.70 | Electrophysiological and antiarrhythmic effects of the atrial selective 5-HT(4) receptor antagonist RS-100302 in experimental atrial flutter and fibrillation. ( Cotter, B; Eglen, RM; Feld, GK; Ford, AP; Leistad, E; Mohabir, R; Rahme, MM; Wadhwa, MK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caraballo, L | 1 |
| Molina, G | 1 |
| Weitz, D | 1 |
| Piskulic, L | 1 |
| Avila, A | 1 |
| Marzi, M | 1 |
| Deneer, VH | 1 |
| Lie-A-Huen, L | 1 |
| Kingma, JH | 1 |
| Proost, JH | 1 |
| Gossen, SA | 1 |
| Stuurman, A | 1 |
| Uytdehaag, GM | 1 |
| Dunselman, PH | 1 |
| Brouwers, JR | 1 |
| Rahme, MM | 1 |
| Cotter, B | 1 |
| Leistad, E | 1 |
| Wadhwa, MK | 1 |
| Mohabir, R | 1 |
| Ford, AP | 1 |
| Eglen, RM | 1 |
| Feld, GK | 1 |
1 review available for cisapride and Atrial Fibrillation
| Article | Year |
|---|---|
[Proarrhythmic effects of domperidone in infants: a systematic review].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Cisapride; Contraindications; Cytochrome P-450 CYP3A; Dom | 2014 |
1 trial available for cisapride and Atrial Fibrillation
| Article | Year |
|---|---|
Absorption kinetics and pharmacodynamics of two oral dosage forms of flecainide in patients with an episode of paroxysmal atrial fibrillation.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Anti-Ulcer Agents; Area Under Curve; Atrial Fibrillati | 2004 |
1 other study available for cisapride and Atrial Fibrillation
| Article | Year |
|---|---|
Electrophysiological and antiarrhythmic effects of the atrial selective 5-HT(4) receptor antagonist RS-100302 in experimental atrial flutter and fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cisapride; Electrocardiography | 1999 |