cisapride has been researched along with Abnormalities, Drug-Induced in 2 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this prospective multicenter study was to determine whether cisapride is associated with increased risk of malformations, spontaneous abortions, or decreased birthweight when used during pregnancy." | 7.69 | Cisapride use during human pregnancy: a prospective, controlled multicenter study. ( Addis, A; Bailey, B; Bonati, M; Conover, B; De Souza, CF; Garbis, H; Koren, G; Lau, M; Lee, A; Mastroiacovo, P; Matsui, D; Mazzone, T; Paolini, C; Sanghvi, K; Schechtman, AS; Val, T, 1997) |
| "The objective of this prospective multicenter study was to determine whether cisapride is associated with increased risk of malformations, spontaneous abortions, or decreased birthweight when used during pregnancy." | 3.69 | Cisapride use during human pregnancy: a prospective, controlled multicenter study. ( Addis, A; Bailey, B; Bonati, M; Conover, B; De Souza, CF; Garbis, H; Koren, G; Lau, M; Lee, A; Mastroiacovo, P; Matsui, D; Mazzone, T; Paolini, C; Sanghvi, K; Schechtman, AS; Val, T, 1997) |
| " Instead, single dosing on specific days is proposed to be a better way to characterize the teratogenic potential of Ikr blocking drugs." | 2.44 | Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs. ( Danielsson, BR; Danielsson, C; Nilsson, MF, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danielsson, BR | 1 |
| Danielsson, C | 1 |
| Nilsson, MF | 1 |
| Bailey, B | 1 |
| Addis, A | 1 |
| Lee, A | 1 |
| Sanghvi, K | 1 |
| Mastroiacovo, P | 1 |
| Mazzone, T | 1 |
| Bonati, M | 1 |
| Paolini, C | 1 |
| Garbis, H | 1 |
| Val, T | 1 |
| De Souza, CF | 1 |
| Matsui, D | 1 |
| Schechtman, AS | 1 |
| Conover, B | 1 |
| Lau, M | 1 |
| Koren, G | 1 |
1 review available for cisapride and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; | 2007 |
1 other study available for cisapride and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Cisapride use during human pregnancy: a prospective, controlled multicenter study.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Birth Weight; Case-Control Studies; Cisap | 1997 |