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cisapride and Abdominal Pain

cisapride has been researched along with Abdominal Pain in 10 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.

Research Excerpts

ExcerptRelevanceReference
"Although combination antiemetics prevent vomiting during the initial 24 h after high-dose (> or =100 mg/m2) cisplatin, many patients experience delayed emesis 24-120 h afterwards despite receiving prophylactic dexamethasone and metoclopramide during this time."9.09Oral cisapride for the control of delayed vomiting following high-dose cisplatin. ( Baltzer, L; Grant, SC; Hinckley, L; Kris, MG; Miller, VA; Pisters, KM; Pizzo, BA, 1999)
"A controlled multi-centre clinical trial was conducted for evaluating the efficacy and safety of cisapride in the treatment of 414 cases of functional dyspepsia with 169 cases as control."9.08[A controlled multi-centre clinical trial on cisapride in treatment of functional dyspepsia]. ( Jia, B; Liang, X; Wang, B, 1995)
"To study the effect of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome."9.08Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome. ( Brandstätter, G; Dragosics, B; Hentschel, E; Judmaier, G; Schütze, K, 1997)
"The effects of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome (IBS) were evaluated in a randomized, double-blind, placebo-controlled study."9.07"Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride. ( Milo, R; Toussaint, J; Van Eeghem, P; Van Outryve, M, 1991)
"Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown."6.68The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997)
"Cisapride was well tolerated."6.67Cisapride in functional dyspepsia: a double-blind, placebo-controlled randomized trial in general practice patients. ( Cochran, KM; Penney, SC; Wood, SF, 1993)
"Although combination antiemetics prevent vomiting during the initial 24 h after high-dose (> or =100 mg/m2) cisplatin, many patients experience delayed emesis 24-120 h afterwards despite receiving prophylactic dexamethasone and metoclopramide during this time."5.09Oral cisapride for the control of delayed vomiting following high-dose cisplatin. ( Baltzer, L; Grant, SC; Hinckley, L; Kris, MG; Miller, VA; Pisters, KM; Pizzo, BA, 1999)
"A controlled multi-centre clinical trial was conducted for evaluating the efficacy and safety of cisapride in the treatment of 414 cases of functional dyspepsia with 169 cases as control."5.08[A controlled multi-centre clinical trial on cisapride in treatment of functional dyspepsia]. ( Jia, B; Liang, X; Wang, B, 1995)
"To study the effect of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome."5.08Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome. ( Brandstätter, G; Dragosics, B; Hentschel, E; Judmaier, G; Schütze, K, 1997)
"The effects of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome (IBS) were evaluated in a randomized, double-blind, placebo-controlled study."5.07"Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride. ( Milo, R; Toussaint, J; Van Eeghem, P; Van Outryve, M, 1991)
"Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown."2.68The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997)
"Cisapride was well tolerated."2.67Cisapride in functional dyspepsia: a double-blind, placebo-controlled randomized trial in general practice patients. ( Cochran, KM; Penney, SC; Wood, SF, 1993)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (90.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bassotti, G1
Sietchiping-Nzepa, F1
de Roberto, G1
Castellani, D1
Morelli, A1
Wang, B1
Liang, X1
Jia, B1
Wood, SF1
Penney, SC1
Cochran, KM1
Haycox, A1
Schütze, K1
Brandstätter, G1
Dragosics, B1
Judmaier, G1
Hentschel, E1
Hatlebakk, JG1
Johnsson, F1
Vilien, M1
Carling, L1
Wetterhus, S1
Thøgersen, T1
Pizzo, BA1
Pisters, KM1
Miller, VA1
Grant, SC1
Baltzer, L1
Hinckley, L1
Kris, MG1
Mayer, EA1
Lembo, T1
Chang, L1
Sanger, GJ1
Van Outryve, M1
Milo, R1
Toussaint, J1
Van Eeghem, P1

Reviews

2 reviews available for cisapride and Abdominal Pain

ArticleYear
Approaches to the modulation of abdominal pain.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1999, Volume: 13 Suppl A

    Topics: Abdominal Pain; Animals; Antidepressive Agents, Tricyclic; Cisapride; Colonic Diseases, Functional;

1999
Hypersensitivity and hyperreactivity in the irritable bowel syndrome: An opportunity for drug discovery.
    Digestive diseases (Basel, Switzerland), 1999, Volume: 17, Issue:2

    Topics: Abdominal Pain; Afferent Pathways; Animals; Cisapride; Colonic Diseases, Functional; Constipation; D

1999

Trials

6 trials available for cisapride and Abdominal Pain

ArticleYear
[A controlled multi-centre clinical trial on cisapride in treatment of functional dyspepsia].
    Zhonghua nei ke za zhi, 1995, Volume: 34, Issue:3

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Diarrhea; Dyspepsia; Female; Humans; Male; Middl

1995
Cisapride in functional dyspepsia: a double-blind, placebo-controlled randomized trial in general practice patients.
    Scandinavian journal of gastroenterology. Supplement, 1993, Volume: 195

    Topics: Abdominal Pain; Adult; Aged; Chronic Disease; Cisapride; Double-Blind Method; Dyspepsia; Family Prac

1993
Double-blind study of the effect of cisapride on constipation and abdominal discomfort as components of the irritable bowel syndrome.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:2

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Doub

1997
The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:11

    Topics: Abdominal Pain; Cisapride; Constipation; Diarrhea; Drug Administration Schedule; Endoscopy; Esophagi

1997
Oral cisapride for the control of delayed vomiting following high-dose cisplatin.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Aged; Antiemetics; Antineoplastic Agents; Cisapride; Cisplatin

1999
"Prokinetic" treatment of constipation-predominant irritable bowel syndrome: a placebo-controlled study of cisapride.
    Journal of clinical gastroenterology, 1991, Volume: 13, Issue:1

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Cisapride; Colonic Diseases, Functional; Constipation; Defe

1991

Other Studies

2 other studies available for cisapride and Abdominal Pain

ArticleYear
Pseudo-pseudo-obstruction.
    European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:10

    Topics: Abdominal Pain; Chronic Disease; Cisapride; Diagnosis, Differential; Female; Gastrointestinal Agents

2004
[Management of dyspepsia. Management plan aimed at prevention of upper abdominal complaints].
    Der Internist, 1996, Volume: 37, Issue:12 Suppl M

    Topics: Abdominal Pain; Anti-Ulcer Agents; Cisapride; Dyspepsia; Esophagitis, Peptic; Humans; Piperidines

1996