cisapride has been researched along with ANS (Autonomic Nervous System) Diseases in 14 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
| Excerpt | Relevance | Reference |
|---|---|---|
| " While both cisapride and metoclopramide normalized impaired solid emptying, cisapride at its highest dosage (10 mg) resulted in significantly faster gastric emptying (P = 0." | 2.67 | Cisapride vs metoclopramide. An acute study in diabetic gastroparesis. ( Diamant, NE; Lico, S; McHugh, S, 1992) |
| "Cisapride is a prokinetic drug of the gastrointestinal tract and acts by releasing acetylcholine from cholinergic nerve endings." | 1.31 | Cisapride improves gallbladder emptying in patients with type 2 diabetes mellitus. ( Arke, L; Bhansali, A; Chawla, YK; Dhiman, RK; Gupta, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 11 (78.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gumurdulu, Y | 1 |
| Yapar, Z | 1 |
| Canataroglu, A | 1 |
| Serin, E | 1 |
| Gumurdulu, D | 1 |
| Kibar, M | 1 |
| Colakoglu, S | 1 |
| Räihä, I | 1 |
| Sourander, L | 1 |
| Camilleri, M | 2 |
| Balm, RK | 2 |
| Zinsmeister, AR | 2 |
| Kawagishi, T | 1 |
| Nishizawa, Y | 1 |
| Okuno, Y | 1 |
| Sekiya, K | 1 |
| Morii, H | 1 |
| Doxey, DL | 3 |
| Tothill, S | 1 |
| Milne, EM | 3 |
| Davis, Z | 1 |
| Harter, A | 1 |
| Woodman, MP | 1 |
| Cuddeford, D | 1 |
| Pearson, RA | 1 |
| Stacher, G | 1 |
| Schernthaner, G | 1 |
| Francesconi, M | 1 |
| Kopp, HP | 1 |
| Bergmann, H | 1 |
| Stacher-Janotta, G | 1 |
| Weber, U | 1 |
| Dhiman, RK | 1 |
| Arke, L | 1 |
| Bhansali, A | 1 |
| Gupta, S | 1 |
| Chawla, YK | 1 |
| Bergmann, JF | 1 |
| Chassany, O | 1 |
| Guillausseau, PJ | 1 |
| Bayle, M | 1 |
| Chagnon, S | 1 |
| Caulin, C | 1 |
| Sallenave, JR | 1 |
| McHugh, S | 1 |
| Lico, S | 1 |
| Diamant, NE | 1 |
| Wehrmann, T | 1 |
| Lembcke, B | 1 |
| Caspary, WF | 1 |
| de Caestecker, JS | 1 |
| Ewing, DJ | 1 |
| Tothill, P | 1 |
| Clarke, BF | 1 |
| Heading, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 trials available for cisapride and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Determinants of response to a prokinetic agent in neuropathic chronic intestinal motility disorder.
Topics: Adult; Autonomic Nervous System; Autonomic Nervous System Diseases; Chronic Disease; Cisapride; Doub | 1994 |
Effect of cisapride on gastric emptying of indigestible solids and plasma motilin concentration in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Cisapride; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1993 |
Symptomatic improvement with one-year cisapride treatment in neuropathic chronic intestinal dysmotility.
Topics: Adult; Aged; Anti-Ulcer Agents; Autonomic Nervous System Diseases; Chronic Disease; Cisapride; Femal | 1996 |
An evaluation of the use of cisapride in horses with chronic grass sickness (equine dysautonomia)
Topics: Animals; Anti-Ulcer Agents; Autonomic Nervous System Diseases; Chronic Disease; Cisapride; Female; G | 1996 |
Cisapride versus placebo for 8 weeks on glycemic control and gastric emptying in insulin-dependent diabetes: a double blind cross-over trial.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Glucose; Cardiovascular System; Cisapride; Cro | 1999 |
Simultaneous noninvasive evaluation of gastric emptying and orocaecal transit times. Use in studying the actions of cisapride in diabetic patients.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Cisapride; Diabetic Neuropathies; Double-Blind Metho | 1992 |
Cisapride vs metoclopramide. An acute study in diabetic gastroparesis.
Topics: Adult; Autonomic Nervous System Diseases; Cisapride; Diabetic Neuropathies; Dose-Response Relationsh | 1992 |
Influence of cisapride on antroduodenal motor function in healthy subjects and diabetics with autonomic neuropathy.
Topics: Adult; Autonomic Nervous System Diseases; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathie | 1991 |
Evaluation of oral cisapride and metoclopramide in diabetic autonomic neuropathy: an eight-week double-blind crossover study.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cisapride; Diabetic Neuropathies; Double-Bl | 1989 |
5 other studies available for cisapride and ANS (Autonomic Nervous System) Diseases
| Article | Year |
|---|---|
Gastric emptying time and the effect of cisapride in cirrhotic patients with autonomic neuropathy.
Topics: Administration, Oral; Adult; Aged; Ascites; Autonomic Nervous System Diseases; Cisapride; Female; Ga | 2003 |
GI motility disorders: diagnostic workup and use of prokinetic therapy.
Topics: Aging; Anti-Ulcer Agents; Autonomic Nervous System Diseases; Cisapride; Diet; Gastrointestinal Disea | 1993 |
Patterns of feeding and behaviour in horses recovering from dysautonomia (grass sickness).
Topics: Animal Feed; Animals; Appetitive Behavior; Autonomic Nervous System Diseases; Behavior, Animal; Cisa | 1995 |
Recovery of horses from dysautonomia (grass sickness).
Topics: Animals; Autonomic Nervous System Diseases; Chronic Disease; Cisapride; Female; Follow-Up Studies; G | 1995 |
Cisapride improves gallbladder emptying in patients with type 2 diabetes mellitus.
Topics: Acetylcholine; Administration, Oral; Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Cis | 2001 |