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cisapride and A-V Dissociation

cisapride has been researched along with A-V Dissociation in 4 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
"7 mM and Mg2+=1 mM), d,l-sotalol (10 and 30 microM), a class III antiarrhythmic drug, prolonged ventricular repolarization, such as QT intervals and monophasic action potential duration, and induced early after-depolarization and polymorphic ventricular tachyarrhythmia."3.71Drug-induced ventricular tachyarrhythmia in isolated rabbit hearts with atrioventricular block. ( Ito, T; Kii, Y, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, MH1
Su, MJ1
Sun, SS1
Kantoch, MJ1
Qurashi, MM1
Bulbul, ZR1
Gorgels, AP1
Sugiyam, A1
Ishida, Y1
Satoh, Y1
Aoki, S1
Hori, M1
Akie, Y1
Kobayashi, Y1
Hashimoto, K1
Kii, Y1
Ito, T1

Other Studies

4 other studies available for cisapride and A-V Dissociation

ArticleYear
Age-related differences in the direct cardiac effects of cisapride: narrower safety range in the hearts of young rabbits.
    Pediatric research, 2003, Volume: 53, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Atrioventricular Node; Bundle of His; Cisapride; Electrocard

2003
A newborn with a complex congenital heart disease, atrioventricular block, and torsade de pointes ventricular tachycardia.
    Pacing and clinical electrophysiology : PACE, 1998, Volume: 21, Issue:12

    Topics: Cisapride; Electrocardiography; Female; Heart Block; Heart Defects, Congenital; Humans; Infant, Newb

1998
Electrophysiological, anatomical and histological remodeling of the heart to AV block enhances susceptibility to arrhythmogenic effects of QT-prolonging drugs.
    Japanese journal of pharmacology, 2002, Volume: 88, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Atrioventricular Node; Blood Pressure; Body Weight; Cisapride; Dogs;

2002
Drug-induced ventricular tachyarrhythmia in isolated rabbit hearts with atrioventricular block.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:5

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzamides; Cisapride; Dimethyl Sulfoxide; Disea

2002