cirazoline has been researched along with Muscle Contraction in 20 studies
cirazoline: posseses agonist properties at alpha-adrenoreceptor sites; RN given refers to parent cpd
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxymetazoline was less effective, indanidine and clonidine were ineffective." | 1.32 | Contractile actions of imidazoline alpha-adrenoceptor agonists and effects of noncompetitive alpha1-adrenoceptor antagonists in human vas deferens. ( Amobi, N; Guillebaud, J; Kaisary, A; Lloyd-Davies, RW; Smith, IC; Turner, E, 2003) |
| "Methoxamine was a partial agonist relative to norepinephrine whereas clonidine, xylazine, B-HT 920 and B-HT 933 produced minimal contractions." | 1.27 | Alpha-1 adrenoceptors and calcium in isolated canine coronary arteries. ( Aarhus, LL; Rimele, TJ; Rooke, TW; Vanhoutte, PM, 1983) |
| "(-) Idazoxan was selective for postsynaptic alpha 2-adrenoceptors and antagonized presynaptic alpha 2-adrenoceptors of the rat." | 1.27 | (Imidazolinyl-2)-2-benzodioxane 1-4 (idazoxan) and its stereoisomers, new alpha 2-antagonists. ( Dabiré, H; Mouille, P; Schmitt, H, 1985) |
| "Cirazoline was found to be a full agonist at alpha-1 receptors having an ED50, dissociation constant (KA) and relative efficacy similar to that of (-)-norepinephrine." | 1.26 | Receptor interactions of imidazolines. IX. Cirazoline is an alpha-1 adrenergic agonist and an alpha-2 adrenergic antagonist. ( Ruffolo, RR; Waddell, JE, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (65.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amobi, N | 1 |
| Guillebaud, J | 1 |
| Kaisary, A | 1 |
| Lloyd-Davies, RW | 1 |
| Turner, E | 1 |
| Smith, IC | 1 |
| Gillespie, JI | 1 |
| Mita, M | 2 |
| Walsh, MP | 2 |
| Saito, M | 1 |
| Shakirova, Y | 1 |
| Bonnevier, J | 1 |
| Albinsson, S | 1 |
| Adner, M | 1 |
| Rippe, B | 1 |
| Broman, J | 1 |
| Arner, A | 1 |
| Swärd, K | 1 |
| Ruffolo, RR | 2 |
| Morgan, EL | 1 |
| Messick, K | 1 |
| Waddell, JE | 1 |
| Rimele, TJ | 1 |
| Rooke, TW | 1 |
| Aarhus, LL | 1 |
| Vanhoutte, PM | 1 |
| Docherty, JR | 2 |
| McGrath, JC | 1 |
| Joly, G | 1 |
| Mouillé, P | 2 |
| Dabiré, H | 2 |
| Lucet, B | 1 |
| Schmitt, H | 2 |
| Lues, I | 1 |
| Schümann, HJ | 1 |
| Slavica, M | 1 |
| Lei, L | 1 |
| Patil, PN | 1 |
| Kerezy, A | 1 |
| Feller, DR | 1 |
| Miller, DD | 1 |
| Guc, MO | 1 |
| Furman, BL | 1 |
| Parratt, JR | 1 |
| Jim, KF | 1 |
| Macia, RA | 1 |
| Matthews, WD | 1 |
| Bou, J | 1 |
| Massingham, R | 1 |
| Chiu, AT | 1 |
| McCall, DE | 1 |
| Thoolen, MJ | 1 |
| Timmermans, PB | 1 |
| Williamson, KL | 1 |
| Broadley, KJ | 1 |
| Mottram, DR | 1 |
| Saggar, P | 1 |
20 other studies available for cirazoline and Muscle Contraction
| Article | Year |
|---|---|
Contractile actions of imidazoline alpha-adrenoceptor agonists and effects of noncompetitive alpha1-adrenoceptor antagonists in human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Dibenzylchlorethamine; Dose-Response Relati | 2003 |
Noradrenaline inhibits autonomous activity in the isolated guinea pig bladder.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Autonomic Nervous System; Brimonidine Tartrat | 2004 |
Augmentation of alpha1-adrenoceptor-mediated contraction by warming without increased phosphorylation of myosin in rat caudal arterial smooth muscle.
Topics: Adrenergic alpha-Agonists; Animals; Arteries; Dose-Response Relationship, Drug; Hot Temperature; Imi | 2005 |
Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Caveolae; Caveolin 1; Caveolin 2; Caveolin 3; Enzyme Ac | 2006 |
Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.
Topics: Animals; Aorta, Thoracic; Azepines; Blood Pressure; Decerebrate State; Diltiazem; Dose-Response Rela | 1984 |
Receptor interactions of imidazolines. IX. Cirazoline is an alpha-1 adrenergic agonist and an alpha-2 adrenergic antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Guinea Pigs; | 1982 |
Alpha-1 adrenoceptors and calcium in isolated canine coronary arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; | 1983 |
An investigation of presynaptic alpha-adrenoceptor subtypes in the pithed rat heart and in the rat isolated vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Electric Stimulation; Ethanolamines; Heart Rate; | 1984 |
The actions of cirazoline on the rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Imidazoles; In Vitro Techniques; Isometric Contractio | 1984 |
Pre- and postsynaptic alpha-adrenoceptor blocking properties of a new dihydrobenzofurane derivative (imidazolinyl-2)-2-dihydro 2,3 benzofurane (S 9871) and its stereoisomers in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Benzofurans; Blood Pressure; Clonidine; Drug Intera | 1984 |
Effect of removing the endothelial cells on the reactivity of rat aortic segments to different alpha-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Clonidine; Endothelium; Imidazoles; I | 1984 |
Synthesis and biological activities of a new set of irreversibly acting 2-(4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Calcium Channels; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Mal | 1994 |
alpha1-Adrenoceptor-mediated phosphorylation of myosin in rat-tail arterial smooth muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1997 |
Endotoxin impairs the response of rat anococcygeus muscle to electrical field stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Electric Stimulation; Endotoxins; Escherichia coli; Gu | 1991 |
(Imidazolinyl-2)-2-benzodioxane 1-4 (idazoxan) and its stereoisomers, new alpha 2-antagonists.
Topics: Animals; Azepines; Chickens; Clonidine; Dioxanes; Dioxins; Heart Rate; Idazoxan; Imidazoles; Male; M | 1985 |
An evaluation of the ability of a series of full alpha-1 adrenoceptor agonists to release internal calcium in venous smooth muscle.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Culture Media; Dogs; Imidazoles; Lanthanum; Mathematics | 1985 |
Effect of diltiazem upon contractile responses to phenylephrine, cirazoline, Sgd 101/75, St 587 and B-HT 920 in rabbit aorta and dog saphenous vein preparations.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Benzazepines; Clonidine; Diltiazem; D | 1986 |
Ca++ utilization in the constriction of rat aorta to full and partial alpha-1 adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Calcium; Clonidine; Dose-Response Relationship, Drug; Eth | 1986 |
Characterization of the alpha-adrenoceptors mediating positive inotropy of rat left atria by use of selective agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brimonidine Tartr | 1987 |
Cirazoline, an alpha 2-adrenoceptor antagonist in guinea-pig ileum.
Topics: Acetylcholine; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Female; G | 1985 |