cirazoline has been researched along with Decerebrate Posturing in 18 studies
cirazoline: posseses agonist properties at alpha-adrenoreceptor sites; RN given refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | 5.29 | Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Pretreatment with phenoxybenzamine accentuated the inhibitory actions of captopril and a combination of phenoxybenzamine and captopril significantly increased the ED50 without altering the maximum response." | 1.29 | Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine. ( Tabrizchi, R; Triggle, CR, 1994) |
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | 1.29 | Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Treatment with captopril was found to attenuate pressor responses produced by the administration of either alpha 1- or alpha 2-adrenoceptor agonists, resulting in the displacement to the right of the agonist dose-response curves and significantly increasing the calculated ED50 values." | 1.28 | The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation. ( Tabrizchi, R; Triggle, CR, 1992) |
| " The ED50 value for the dose-response curves to B-HT 920 and St587 were found to be significantly increased after the administration of staurosporine." | 1.28 | Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine. ( Tabrizchi, R; Triggle, CR, 1991) |
| " Furthermore, in the pithed rat, the alpha 1-adrenoceptor-mediated pressor dose-response curve to cirazoline was shifted approximately 6-fold to the right by both the (+)-R- and (-)-S-enantiomers of carvedilol at a dose of 1 mg/kg, i." | 1.28 | The interaction of the enantiomers of carvedilol with alpha 1- and beta 1-adrenoceptors. ( Ashton, DJ; Hieble, JP; Nichols, AJ; Ruffolo, RR; Sulpizio, AC, 1989) |
| ", dose required to produce a two-fold rightward shift in the dose-response curve of cirazoline) of 0." | 1.27 | Interaction of the enantiomers of 3-0-methyldobutamine, a metabolite of dobutamine, with alpha- and beta-adrenoreceptors in the cardiovascular system of the pithed rat. ( Morgan, EL; Ruffolo, R, 1984) |
| " Papaverine, calmidazolium and W-7 did not influence the dose-response curves for the agonists in the pithed rat experiments." | 1.27 | Interaction of calmodulin antagonists with alpha-adrenergic responses in pithed rats and in the perfused hindquarters of the rat. ( Korstanje, C; Ten Brink, EM; Van Zwieten, PA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monroy-Ordoñez, EB | 1 |
| Villalón, CM | 1 |
| Cobos-Puc, LE | 1 |
| Márquez-Conde, JA | 1 |
| Sánchez-López, A | 1 |
| Centurión, D | 1 |
| Ruffolo, RR | 3 |
| Morgan, EL | 2 |
| Messick, K | 1 |
| Ruffolo, R | 1 |
| Tabrizchi, R | 4 |
| Lupichuk, SM | 1 |
| Triggle, CR | 3 |
| Beenen, OH | 1 |
| Mathy, MJ | 2 |
| Pfaffendorf, M | 1 |
| van Zwieten, PA | 5 |
| Alvarez-Guerra, M | 1 |
| Bertholom, N | 1 |
| Garay, RP | 1 |
| Guc, MO | 1 |
| Furman, BL | 1 |
| Paratt, JR | 1 |
| Richer, C | 1 |
| Mulder, P | 1 |
| Doussau, MP | 1 |
| Gautier, P | 1 |
| Giudicelli, JF | 1 |
| Nichols, AJ | 2 |
| Motley, ED | 1 |
| Sulpizio, AC | 1 |
| Ashton, DJ | 1 |
| Hieble, JP | 1 |
| de Jonge, A | 2 |
| van den Berg, G | 1 |
| Qian, JQ | 1 |
| Wilffert, B | 2 |
| Thoolen, MJ | 3 |
| Timmermans, PB | 3 |
| Jie, K | 1 |
| van Brummelen, P | 1 |
| Hiley, CR | 1 |
| Thomas, GR | 1 |
| Korstanje, C | 1 |
| Ten Brink, EM | 1 |
18 other studies available for cirazoline and Decerebrate Posturing
| Article | Year |
|---|---|
Evidence that some imidazoline derivatives inhibit peripherally the vasopressor sympathetic outflow in pithed rats.
Topics: Adrenergic alpha-Agonists; Agmatine; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Blo | 2008 |
Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.
Topics: Animals; Aorta, Thoracic; Azepines; Blood Pressure; Decerebrate State; Diltiazem; Dose-Response Rela | 1984 |
Interaction of the enantiomers of 3-0-methyldobutamine, a metabolite of dobutamine, with alpha- and beta-adrenoreceptors in the cardiovascular system of the pithed rat.
Topics: Animals; Binding, Competitive; Blood Pressure; Catecholamines; Decerebrate State; Dobutamine; Heart | 1984 |
The effects of losartan and captopril on vasopressor actions of cirazoline in the absence and presence of SZL-49 and nifedipine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihyperten | 1995 |
Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Captopril; Decerebrate State; Dose-Response Rela | 1994 |
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimoni | 1996 |
Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1999 |
Modification of alpha-adrenoceptor-mediated pressor responses by NG-nitro-L-arginine methyl ester and vasopressin in endotoxin-treated pithed rats.
Topics: Adrenergic alpha-Agonists; Amino Acid Oxidoreductases; Animals; Arginine; Azepines; Blood Pressure; | 1992 |
The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Captopril; Clonidine; Decerebrate Stat | 1992 |
Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine.
Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate Stat | 1991 |
Systemic and regional haemodynamic interactions between K+ channel openers and the sympathetic nervous system in the pithed SHR.
Topics: Animals; Benzopyrans; Brimonidine Tartrate; Cromakalim; Decerebrate State; Dihydropyridines; Heart R | 1990 |
Effect of pertussis toxin treatment on postjunctional alpha-1 and alpha-2 adrenoceptor function in the cardiovascular system of the pithed rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
The interaction of the enantiomers of carvedilol with alpha 1- and beta 1-adrenoceptors.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Carbazoles; Carvedilol; Decerebrate State; Guinea | 1989 |
Inhibitory effect of alpha-1 adrenoceptor stimulation on cardiac sympathetic neurotransmission in pithed normotensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Decerebrate State; Ethanolamines; Heart; Heart Rate; | 1986 |
Effects of PN 200-110, a new calcium antagonist, on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction elicited by selective alpha-adrenoceptor agonists and catecholamines in the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Catecholamin | 1985 |
Effects of alpha-adrenoceptor agonists on cardiac output and its regional distribution in the pithed rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Cardiac Output; Decerebr | 1987 |
Interaction of calmodulin antagonists with alpha-adrenergic responses in pithed rats and in the perfused hindquarters of the rat.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Calmodulin; Decerebrate State; Heart Rate; Hindl | 1988 |
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Dr | 1985 |