ciprofloxacin has been researched along with Tuberculosis, Meningeal in 4 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Tuberculosis, Meningeal: A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the entry of ciprofloxacin into the cerebrospinal fluid (CSF) in 37 patients with various types of meningitis (bacterial meningitis 10 patients, viral 12 patients, tuberculous 7 patients)." | 7.68 | Entry of ciprofloxacin into cerebrospinal fluid during bacterial, viral and tuberculous meningitis. ( Barsić, B; Beus, I; Himbele, J; Lisić, M; Marton, E; Schönwald, S, 1991) |
| "Underlying clinical syndromes were viral meningitis (n = 10), convalescent phase of acute bacterial meningitis (n = 9), and acute phase of bacterial meningitis (n = 1)." | 5.28 | Penetration of ciprofloxacin into the spinal fluid in patients with viral and bacterial meningitis. ( Borner, K; Ruhnke, M; Trautmann, M, 1990) |
| "We studied the entry of ciprofloxacin into the cerebrospinal fluid (CSF) in 37 patients with various types of meningitis (bacterial meningitis 10 patients, viral 12 patients, tuberculous 7 patients)." | 3.68 | Entry of ciprofloxacin into cerebrospinal fluid during bacterial, viral and tuberculous meningitis. ( Barsić, B; Beus, I; Himbele, J; Lisić, M; Marton, E; Schönwald, S, 1991) |
| "Underlying clinical syndromes were viral meningitis (n = 10), convalescent phase of acute bacterial meningitis (n = 9), and acute phase of bacterial meningitis (n = 1)." | 1.28 | Penetration of ciprofloxacin into the spinal fluid in patients with viral and bacterial meningitis. ( Borner, K; Ruhnke, M; Trautmann, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thwaites, GE | 1 |
| Bhavnani, SM | 1 |
| Chau, TT | 1 |
| Hammel, JP | 1 |
| Török, ME | 1 |
| Van Wart, SA | 1 |
| Mai, PP | 1 |
| Reynolds, DK | 1 |
| Caws, M | 1 |
| Dung, NT | 1 |
| Hien, TT | 1 |
| Kulawy, R | 1 |
| Farrar, J | 1 |
| Ambrose, PG | 1 |
| Fisher, M | 1 |
| Tomlinson, DR | 1 |
| Coker, RJ | 1 |
| Barsić, B | 1 |
| Himbele, J | 1 |
| Beus, I | 1 |
| Schönwald, S | 1 |
| Marton, E | 1 |
| Lisić, M | 1 |
| Trautmann, M | 1 |
| Ruhnke, M | 1 |
| Borner, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis[NCT03092817] | Phase 3 | 520 participants (Actual) | Interventional | 2017-05-25 | Active, not recruiting | ||
| A Randomized Double Blind Placebo Controlled Non-inferiority Trial of Adjunctive Dexamethasone for the Treatment of HIV-uninfected Adults With Tuberculous Meningitis Stratified by Leukotriene A4 Hydrolase Genotype[NCT03100786] | Phase 3 | 640 participants (Anticipated) | Interventional | 2018-02-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ciprofloxacin and Tuberculosis, Meningeal
| Article | Year |
|---|---|
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; | 2011 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; | 2011 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; | 2011 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; | 2011 |
3 other studies available for ciprofloxacin and Tuberculosis, Meningeal
| Article | Year |
|---|---|
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group.
Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitu | 1996 |
Entry of ciprofloxacin into cerebrospinal fluid during bacterial, viral and tuberculous meningitis.
Topics: Adult; Bacterial Infections; Ciprofloxacin; Humans; Meningitis; Meningitis, Viral; Middle Aged; Tube | 1991 |
Penetration of ciprofloxacin into the spinal fluid in patients with viral and bacterial meningitis.
Topics: Adult; Aged; Ciprofloxacin; Female; Humans; Male; Meningitis; Meningitis, Viral; Middle Aged; Tuberc | 1990 |