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ciprofloxacin and Trypanosomiasis, African

ciprofloxacin has been researched along with Trypanosomiasis, African in 4 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Research Excerpts

ExcerptRelevanceReference
"Human African trypanosomiasis (HAT) or sleeping sickness is caused by two subspecies of Trypanosoma brucei , Trypanosoma brucei gambiense , and Trypanosoma brucei rhodesiense and is one of Africa's old plagues."1.38Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei. ( Braunschweig, H; Damme, A; Engstler, M; Hiltensperger, G; Holzgrabe, U; Jones, NG; Jung, J; Kaiser, M; Meinel, L; Niedermeier, S; Puhl, S; Stich, A, 2012)
"Furthermore, opportunistic secondary bacterial infection during trypanosomosis did not seem to play an important role in the changes in plasma LBP levels."1.35Lipopolysaccharide binding protein in the acute phase response of experimental murine Trypanosoma brucei brucei infection. ( Burke, J; Eckersall, PD; Jennings, FW; Mburu, JN; Mungatana, NK; Murray, M; Ngure, RM, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hiltensperger, G1
Jones, NG1
Niedermeier, S1
Stich, A1
Kaiser, M1
Jung, J1
Puhl, S1
Damme, A1
Braunschweig, H1
Meinel, L1
Engstler, M1
Holzgrabe, U1
Pomel, S1
Dubar, F1
Forge, D1
Loiseau, PM1
Biot, C1
Ngure, RM1
Eckersall, PD2
Mungatana, NK1
Mburu, JN1
Jennings, FW2
Burke, J2
Murray, M2
Ngure, R1
Mbai, FN1

Other Studies

4 other studies available for ciprofloxacin and Trypanosomiasis, African

ArticleYear
Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Acute Disease; Animals; Cell Line; DNA Topoisomerases, Type II; DNA, Kinetoplast; Mice; Microscopy,

2012
New heterocyclic compounds: Synthesis and antitrypanosomal properties.
    Bioorganic & medicinal chemistry, 2015, Aug-15, Volume: 23, Issue:16

    Topics: Aminoquinolines; Animals; Benzimidazoles; Cell Line; Ferrous Compounds; Halogenation; Heterocyclic C

2015
Lipopolysaccharide binding protein in the acute phase response of experimental murine Trypanosoma brucei brucei infection.
    Research in veterinary science, 2009, Volume: 86, Issue:3

    Topics: Acute-Phase Proteins; Animals; Anti-Bacterial Agents; Bacterial Infections; Carrier Proteins; Ciprof

2009
Secondary bacterial infection in plasma endotoxin levels and the acute-phase response of mice infected with Trypanosoma brucei brucei.
    Parasite immunology, 2009, Volume: 31, Issue:7

    Topics: Acute-Phase Reaction; Animals; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Endotoxem

2009