Page last updated: 2024-10-25

ciprofloxacin and Stevens-Johnson Syndrome

ciprofloxacin has been researched along with Stevens-Johnson Syndrome in 22 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research Excerpts

ExcerptRelevanceReference
" Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0."5.35Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009)
"This survey considers 8 cases of toxic epidermal necrolysis diagnosed and treated in our clinic from 2003 to 2007."1.36Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis. ( Hanken, I; Sander, CA; Schimmer, M, 2010)
" Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0."1.35Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009)
"Toxic epidermal necrolysis (TEN), or Lyell's syndrome, is a fulminant bullous dermatitis."1.32Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus. ( Jongen-Lavrencic, M; Schneeberger, PM; van der Hoeven, JG, 2003)
"Skin biopsy confirmed toxic epidermal necrolysis."1.32Ciprofloxacin-induced toxic epidermal necrolysis (TEN) in a nonagerian: a case report. ( Jones, H; Mandal, B; Singh, S; Steward, M, 2004)
"Toxic epidermal necrolysis (TEN) or Lyell's syndrome is a rare fulminating skin disease notorious for its rapidly progressive course and high mortality rate."1.28Plasma exchange (PE) treatment in drug-induced toxic epidermal necrolysis (TEN). ( Alexopoulos, E; Chrisomalis, F; Karpouzas, J; Koukoudis, P; Papadimitriou, M; Papadopoulou, D; Sakellariou, G; Skenteris, N; Tsakaris, D, 1991)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (40.91)18.2507
2000's9 (40.91)29.6817
2010's3 (13.64)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Mortazavi, H1
Rostami, A1
Firooz, A1
Esmaili, N1
Ghiasi, M1
Lajevardi, V1
Amirzargar, AA1
Sheykhi, I1
Khamesipour, A1
Akhdar, M1
Vural, S1
Arakawa, A1
Arakawa, Y1
Prinz, JC1
Moghaddam, S1
Connolly, D1
Okan, G1
Yaylaci, S1
Peker, O1
Kaymakoglu, S1
Saruc, M1
Hanken, I1
Schimmer, M1
Sander, CA1
Upadya, GM1
Ruxana, K1
Cholongitas, E1
Georgousaki, C1
Spyrou, S1
Katsogridakis, K1
Dasenaki, M1
Hällgren, J1
Tengvall-Linder, M1
Persson, M1
Wahlgren, CF1
Jongen-Lavrencic, M1
Schneeberger, PM1
van der Hoeven, JG1
Mandal, B1
Steward, M1
Singh, S1
Jones, H1
Famularo, G1
Di Dona, B1
Canzona, F1
Girardelli, CR1
Cruciani, G1
Bhatia, RS1
Gohel, DR1
Oza, JJ1
Kamili, MA1
Ali, G1
Rashid, S1
Mansoor, A1
Allaqaband, GQ1
Win, A1
Evers, ML1
Chmel, H1
Moshfeghi, M1
Mandler, HD1
Yerasi, AB1
Oertel, MD1
Livasy, CA1
Kaplan, AM1
Vélez, A1
Moreno, JC1
Kundu, AK1
Tham, TC1
Allen, G1
Hayes, D1
McGrady, B1
Riddell, JG1
Sakellariou, G1
Koukoudis, P1
Karpouzas, J1
Alexopoulos, E1
Papadopoulou, D1
Chrisomalis, F1
Skenteris, N1
Tsakaris, D1
Papadimitriou, M1

Reviews

2 reviews available for ciprofloxacin and Stevens-Johnson Syndrome

ArticleYear
Stevens-Johnson syndrome associated with ciprofloxacin: a review of adverse cutaneous events reported in Sweden as associated with this drug.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:5 Suppl

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Ciprofloxacin; Female; Humans

2003
Ciprofloxacin-induced toxic epidermal necrolysis: a case report.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Fatal Outcome; Female; Humans; Leg Ulcer; Male; M

1997

Other Studies

20 other studies available for ciprofloxacin and Stevens-Johnson Syndrome

ArticleYear
Association between human leukocyte antigens and cutaneous adverse drug reactions to antiepileptics and antibiotics in the Iranian population.
    Dermatologic therapy, 2022, Volume: 35, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Case-Control Studies; Ciprofloxacin; F

2022
The therapeutic potential of TNF-α antagonists in toxic epidermal necrosis: insights from two cases and adverse event reports.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:11

    Topics: Adalimumab; Anti-Bacterial Agents; Ciprofloxacin; Dermatologic Agents; Etanercept; Female; Humans; M

2018
Photo-induced Stevens-Johnson syndrome.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:3

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Dermatitis, Phototoxic; Disease Progression; Female; Humans; S

2014
Vanishing bile duct and Stevens-Johnson syndrome associated with ciprofloxacin treated with tacrolimus.
    World journal of gastroenterology, 2008, Aug-07, Volume: 14, Issue:29

    Topics: Adult; Bile Duct Diseases; Ciprofloxacin; Deglutition Disorders; Dysuria; Female; Humans; Immunosupp

2008
Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2010, Volume: 8, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antico

2010
Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:10

    Topics: Administration, Oral; Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Ciproflo

2009
Stevens-Johnson syndrome related to ciprofloxacin, possibly enhanced by overadministration of levothyroxine.
    Dermatology online journal, 2009, Nov-15, Volume: 15, Issue:11

    Topics: Aged; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactio

2009
Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus.
    Infection, 2003, Volume: 31, Issue:6

    Topics: Adult; Ciprofloxacin; Combined Modality Therapy; Disease Progression; Fatal Outcome; Female; Humans;

2003
Ciprofloxacin-induced toxic epidermal necrolysis (TEN) in a nonagerian: a case report.
    Age and ageing, 2004, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Fatal Outcome; Female; Humans; Steven

2004
Etanercept for toxic epidermal necrolysis.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:6

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Etanercept; Humans; Immunoglobulin G; Immunologic Factors; Mal

2007
Steven Johnson syndrome following a single dose of ciprofloxacin.
    The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:4

    Topics: Administration, Oral; Adult; Ciprofloxacin; Drug Eruptions; Humans; Male; Stevens-Johnson Syndrome

1994
Steven-Johnson's syndrome following single dose of ciprofloxacin.
    The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:8

    Topics: Ciprofloxacin; Humans; Stevens-Johnson Syndrome

1994
Ciprofloxacin induced Stevens-Johnson syndrome.
    The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:9

    Topics: Ciprofloxacin; Female; Humans; Stevens-Johnson Syndrome

1994
Stevens-Johnson syndrome presumably induced by ciprofloxacin.
    International journal of dermatology, 1994, Volume: 33, Issue:7

    Topics: Adult; Ciprofloxacin; Humans; Male; Penicillin G; Stevens-Johnson Syndrome; Streptococcal Infections

1994
Ciprofloxacin-induced toxic epidermal necrolysis.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:12

    Topics: Administration, Oral; Adult; Ciprofloxacin; Female; Hospitals, University; Humans; Lupus Erythematos

1993
Ciprofloxacin-induced toxic epidermal necrolysis.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Fatal Outcome; Humans; Male; Stevens-Johnson Syndrome

1996
Second case of ranitidine-related toxic epidermal necrolysis in a patient with idiopathic thrombocytopenic purpura.
    Journal of the American Academy of Dermatology, 2000, Volume: 42, Issue:2 Pt 1

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Female; Fluid Therapy; Histamine H2 Antagonists; Humans

2000
Ciprofloxacin-induced severe cutaneous reaction and haemolysis in a young adult.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:6

    Topics: Adolescent; Anemia, Hemolytic; Ciprofloxacin; Drug Eruptions; Glucosephosphate Dehydrogenase Deficie

2000
Possible association between toxic epidermal necrolysis and ciprofloxacin.
    Lancet (London, England), 1991, Aug-24, Volume: 338, Issue:8765

    Topics: Aged; Ciprofloxacin; Combined Modality Therapy; Humans; Male; Product Surveillance, Postmarketing; S

1991
Plasma exchange (PE) treatment in drug-induced toxic epidermal necrolysis (TEN).
    The International journal of artificial organs, 1991, Volume: 14, Issue:10

    Topics: Aged; Allopurinol; Amoxicillin; Carbamazepine; Child; Ciprofloxacin; Humans; Male; Mefenamic Acid; M

1991