Page last updated: 2024-10-25

ciprofloxacin and Rhinoscleroma

ciprofloxacin has been researched along with Rhinoscleroma in 15 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Rhinoscleroma: A granulomatous disease caused by KLEBSIELLA RHINOSCLEROMATIS infection. Despite its name, this disease is not limited to the nose and NASOPHARYNX but may affect any part of the RESPIRATORY TRACT, sometimes with extension to the lip and the skin.

Research Excerpts

ExcerptRelevanceReference
"Klebsiella rhinoscleromatis is the causative agent of this infection and the Mikulicz cell is specific to the lesion being a large macrophage with clear cytoplasm containing the bacilli."5.31A case of rhinoscleroma treated with ciprofloxacin. ( Badia, L; Lund, VJ, 2001)
"Rhinoscleroma is a granulomatous infection of the nasal cavities due to enteric bacterium belonging to the Klebsiella family (Klebsiella rhinoscleromatis)."1.48[Rhinoscleroma: a rare chronic infection of the nasal cavities]. ( Ghorbel, AM; Kallel, S, 2018)
"Rhinoscleroma is a chronic infectious disease that is endemic in certain poor areas of the world."1.48Rhinoscleroma: a chronic infectious disease of poor areas with characteristic histological features - report of a series of six cases. ( Ben Mansour, N; Chbani, L; Efared, B; El Fatemi, H; Gabrielle, AE; Hammas, N, 2018)
"Rhinoscleroma is a specific granulomatous and chronic disorder with insidious evolution."1.48[Rhinoscleroma of the cavum with expression in cervical lymph nodes: about a case]. ( Benayad, J; Benbouzid, MA; El Ayoubi, A; Essakalli, L; Lachhab, O; Lassikri, O, 2018)
"Klebsiella rhinoscleromatis is the causative agent of this infection and Mikulicz cells are specific to this lesion."1.42Rhinoscleroma of nose extruding into oral cavity. ( Desai, D; Ingaleshwar, PS; K V, S; Nayak, P; Pandit, S; R C, P, 2015)
"Rhinoscleroma is a chronic, slowly progressive, inflammatory disease of the upper respiratory tract."1.38Rhinoscleroma: a case series. ( Neoh, CY; Tan, HH; Tan, SL, 2012)
"Rhinoscleroma has become a more and more rare disease because of the sensitivity to the new molecules."1.37Retrospective study of the rhinoscleroma about 14 cases in ENT departments of university hospitals (Côte d'Ivoire). ( Kacouchia, N; Koffi-N'guessan, L; Kouassi, M; Kouassi-Ndjeundo, J; Mobio, NM; N'gattia, KV; Vroh Bi, TS; Yoda, M, 2011)
"Klebsiella rhinoscleromatis is the causative agent of this infection and the Mikulicz cell is specific to the lesion being a large macrophage with clear cytoplasm containing the bacilli."1.31A case of rhinoscleroma treated with ciprofloxacin. ( Badia, L; Lund, VJ, 2001)
"Rhinoscleroma is a very rare cause of upper airway obstruction with only isolated reports in the literature of rhinoscleroma with isolated tracheal obstruction."1.31Upper airway obstruction due to rhinoscleroma: case report. ( Al Jahdali, H; Al Othman, A; Al-Zuwayed, M; Bamefleh, H; Memish, Z, 2001)
"Rhinoscleroma is a rare infectious disease of the upper respiratory tract caused by Klebsiella rhinoscleromatis."1.30[Rhinoscleroma: a case report]. ( Bodlaj, R; Issing, WJ, 1999)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (26.67)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Sadek, HS1
El-Marssafy, LH1
Hussein, FF1
Kallel, S1
Ghorbel, AM1
Gamea, M1
El Tatawi, F1
Elnaggar, A1
Elafandi, H1
Ebeid, K1
Efared, B1
Hammas, N1
Gabrielle, AE1
Ben Mansour, N1
El Fatemi, H1
Chbani, L1
Lassikri, O1
Benayad, J1
Lachhab, O1
El Ayoubi, A1
Benbouzid, MA1
Essakalli, L1
Nayak, P1
R C, P1
K V, S1
Desai, D1
Pandit, S1
Ingaleshwar, PS1
Ramachandran, P1
Piquette, C1
Poole, JA1
N'gattia, KV1
Kacouchia, N1
Koffi-N'guessan, L1
Mobio, NM1
Kouassi-Ndjeundo, J1
Kouassi, M1
Yoda, M1
Vroh Bi, TS1
Tan, SL1
Neoh, CY1
Tan, HH1
Avery, RK1
Salman, SD1
Baker, AS1
Borgstein, J1
Sada, E1
Cortes, R1
Issing, WJ1
Bodlaj, R1
Fajardo-Dolci, G1
Chavolla, R1
Lamadrid-Bautista, E1
Rizo-Alvarez, J1
Badia, L1
Lund, VJ1
Al Jahdali, H1
Bamefleh, H1
Memish, Z1
Al-Zuwayed, M1
Al Othman, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gemifloxacin Versus Ciprofloxacin Versus Rifampicin in Treatment of Rhinoscleroma[NCT03326050]Early Phase 160 participants (Anticipated)Interventional2018-02-28Not yet recruiting
Efficacy Of Doxycycline & Versus Rifampin In Treatment Of Rhinoscleroma[NCT05431673]Phase 145 participants (Anticipated)Interventional2022-08-21Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ciprofloxacin and Rhinoscleroma

ArticleYear
Ciprofloxacin for rhinoscleroma and ozena.
    Lancet (London, England), 1993, Jul-10, Volume: 342, Issue:8863

    Topics: Ciprofloxacin; Female; Humans; Male; Rhinitis, Atrophic; Rhinoscleroma; Rifampin; Trimethoprim, Sulf

1993

Other Studies

14 other studies available for ciprofloxacin and Rhinoscleroma

ArticleYear
First report of rare persistence granulomatous extra respiratory Rhinoscleroma of oral pathology.
    Microbial pathogenesis, 2022, Volume: 164

    Topics: Ciprofloxacin; Female; Humans; Nasal Cavity; Nose; Pathology, Oral; Rhinoscleroma

2022
[Rhinoscleroma: a rare chronic infection of the nasal cavities].
    The Pan African medical journal, 2018, Volume: 31

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Biopsy; Ciprofloxacin; Female; Humans; Klebsiella pneumoni

2018
Topical ciprofloxacin as treatment for rhinoscleroma in a series of 23 patients.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2021, Volume: 46, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Ciprofloxacin; Female; Humans; Ma

2021
Rhinoscleroma: a chronic infectious disease of poor areas with characteristic histological features - report of a series of six cases.
    Tropical doctor, 2018, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Chronic Disease; Ciprofloxacin; Female; Humans; Mal

2018
[Rhinoscleroma of the cavum with expression in cervical lymph nodes: about a case].
    The Pan African medical journal, 2018, Volume: 30

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Female; Follow-Up Studies; Humans; Klebsiella pneumoniae; Lymp

2018
Rhinoscleroma of nose extruding into oral cavity.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25 Suppl 1

    Topics: Anti-Infective Agents; Ciprofloxacin; Female; Humans; Klebsiella pneumoniae; Middle Aged; Mouth; Nas

2015
Rhinoscleroma in a young adult with chronic rhinitis and dyspnea.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2008, Volume: 101, Issue:3

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dyspnea; Female; Humans; Klebsiella pneumoniae; Nasal O

2008
Retrospective study of the rhinoscleroma about 14 cases in ENT departments of university hospitals (Côte d'Ivoire).
    European annals of otorhinolaryngology, head and neck diseases, 2011, Volume: 128, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Combined Modality

2011
Rhinoscleroma: a case series.
    Singapore medical journal, 2012, Volume: 53, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Doxycycline; Drug Therapy, Combination; Female; Humans;

2012
Rhinoscleroma treated with ciprofloxacin: a case report.
    The Laryngoscope, 1995, Volume: 105, Issue:8 Pt 1

    Topics: Adult; Ciprofloxacin; Humans; Male; Rhinoscleroma; Treatment Outcome

1995
[Rhinoscleroma: a case report].
    Laryngo- rhino- otologie, 1999, Volume: 78, Issue:4

    Topics: Adult; Ciprofloxacin; Combined Modality Therapy; Endoscopy; Humans; Klebsiella pneumoniae; Male; Nas

1999
Laryngeal scleroma.
    The Journal of otolaryngology, 1999, Volume: 28, Issue:4

    Topics: Adult; Airway Obstruction; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Laryngeal Diseases;

1999
A case of rhinoscleroma treated with ciprofloxacin.
    The Journal of laryngology and otology, 2001, Volume: 115, Issue:3

    Topics: Adolescent; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Magnetic Resonance Imaging; Rhinos

2001
Upper airway obstruction due to rhinoscleroma: case report.
    Journal of chemotherapy (Florence, Italy), 2001, Volume: 13 Suppl 1

    Topics: Airway Obstruction; Anti-Infective Agents; Bronchoscopy; Ciprofloxacin; Dyspnea; Female; Gram-Negati

2001