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ciprofloxacin and Rhabdomyolysis

ciprofloxacin has been researched along with Rhabdomyolysis in 6 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
"Rhabdomyolysis is one of the serious side effects of ciprofloxacin (CPFX), a widely used antibacterial drug; and occasionally, acute kidney injury (AKI) occurs."7.88Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin. ( Akai, S; Matsubara, A; Oda, S; Tsuneyama, K; Yokoi, T, 2018)
" In this patient, however, the clinical course was dramatically complicated by the development of ciprofloxacin-associated rhabdomyolysis."7.79Ventilator-associated pneumonia caused by OXA-48-producing Escherichia coli complicated by ciprofloxacin-associated rhabdomyolysis. ( Fruhwald, S; Grisold, AJ; Hoenigl, M; Ovcina, I; Valentin, T, 2013)
"As ciprofloxacin is a weak inhibitor of CYP3A4, it is very likely that other mechanisms involving the ATP-binding cassette drug efflux transporter family played a role in this drug interaction."5.35Rhabdomyolysis due to an uncommon interaction of ciprofloxacin with simvastatin. ( Sawant, RD, 2009)
"Rhabdomyolysis is one of the serious side effects of ciprofloxacin (CPFX), a widely used antibacterial drug; and occasionally, acute kidney injury (AKI) occurs."3.88Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin. ( Akai, S; Matsubara, A; Oda, S; Tsuneyama, K; Yokoi, T, 2018)
" In this patient, however, the clinical course was dramatically complicated by the development of ciprofloxacin-associated rhabdomyolysis."3.79Ventilator-associated pneumonia caused by OXA-48-producing Escherichia coli complicated by ciprofloxacin-associated rhabdomyolysis. ( Fruhwald, S; Grisold, AJ; Hoenigl, M; Ovcina, I; Valentin, T, 2013)
"Rhabdomyolysis and acute renal failure were successfully treated by transfusion, diuretic therapy, and glucocorticoid therapy."1.32[Surviving case of Legionella pneumonia showing a high level of serum KL-6 and complicated with rhabdomyolysis]. ( Kawai, A; Nakajima, H; Nakajima, S; Sawaguchi, H; Touda, Y, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsubara, A1
Oda, S1
Akai, S1
Tsuneyama, K1
Yokoi, T1
Grisold, AJ1
Hoenigl, M1
Ovcina, I1
Valentin, T1
Fruhwald, S1
Goldie, FC1
Brogan, A1
Boyle, JG1
Shimura, C1
Saraya, T1
Wada, H1
Takata, S1
Mikura, S1
Yasutake, T1
Kato, J1
Kato, A1
Yamamoto, M1
Watanabe, M1
Yokoyama, T1
Kurai, D1
Ishii, H1
Aoshima, M1
Yamada, A1
Goto, H1
Sawant, RD1
Kawai, A1
Nakajima, H1
Sawaguchi, H1
Touda, Y1
Nakajima, S1

Reviews

1 review available for ciprofloxacin and Rhabdomyolysis

ArticleYear
Pathological evidence of rhabdomyolysis-induced acute tubulointerstitial nephritis accompanying Legionella pneumophila pneumonia.
    Journal of clinical pathology, 2008, Volume: 61, Issue:9

    Topics: Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Humans; Kidney; Legionella pneumophila; Legionna

2008

Other Studies

5 other studies available for ciprofloxacin and Rhabdomyolysis

ArticleYear
Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin.
    Toxicology letters, 2018, Volume: 291

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Atorvastatin; Buth

2018
Ventilator-associated pneumonia caused by OXA-48-producing Escherichia coli complicated by ciprofloxacin-associated rhabdomyolysis.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:6

    Topics: Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Escherichia coli; Escherichia coli Infections

2013
Ciprofloxacin and statin interaction: a cautionary tale of rhabdomyolysis.
    BMJ case reports, 2016, Jul-28, Volume: 2016

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA R

2016
Rhabdomyolysis due to an uncommon interaction of ciprofloxacin with simvastatin.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2009,Winter, Volume: 16, Issue:1

    Topics: Aged; Anti-Infective Agents; ATP-Binding Cassette Transporters; Ciprofloxacin; Cytochrome P-450 CYP3

2009
[Surviving case of Legionella pneumonia showing a high level of serum KL-6 and complicated with rhabdomyolysis].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004, Volume: 42, Issue:8

    Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Antibodies, Bacterial; Antigens; Antigens, Bacteri

2004