Page last updated: 2024-10-25

ciprofloxacin and Pelvic Pain

ciprofloxacin has been researched along with Pelvic Pain in 8 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Pelvic Pain: Pain in the pelvic region of genital and non-genital origin.

Research Excerpts

ExcerptRelevanceReference
" To explore the potential therapeutic benefit of roxithromycin in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), this study compared the effect of roxithromycin with ciprofloxacin and aceclofenac."9.19Clinical efficacy of roxithromycin in men with chronic prostatitis/chronic pelvic pain syndrome in comparison with ciprofloxacin and aceclofenac: a prospective, randomized, multicenter pilot trial. ( Cho, YH; Choe, HS; Han, CH; Lee, SJ; Shim, BS, 2014)
"To investigate the value of Tc-99m ciprofloxacin imaging in the differential diagnosis of chronic bacterial prostatitis."9.10Tc-99m ciprofloxacin imaging in diagnosis of chronic bacterial prostatitis. ( Choe, W; Kim, S; Lee, SM; Moon, Y; Pai, SH; Ryu, JK; Seong, DW; Suh, JK, 2003)
" To explore the potential therapeutic benefit of roxithromycin in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), this study compared the effect of roxithromycin with ciprofloxacin and aceclofenac."5.19Clinical efficacy of roxithromycin in men with chronic prostatitis/chronic pelvic pain syndrome in comparison with ciprofloxacin and aceclofenac: a prospective, randomized, multicenter pilot trial. ( Cho, YH; Choe, HS; Han, CH; Lee, SJ; Shim, BS, 2014)
"To investigate the value of Tc-99m ciprofloxacin imaging in the differential diagnosis of chronic bacterial prostatitis."5.10Tc-99m ciprofloxacin imaging in diagnosis of chronic bacterial prostatitis. ( Choe, W; Kim, S; Lee, SM; Moon, Y; Pai, SH; Ryu, JK; Seong, DW; Suh, JK, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choe, HS1
Lee, SJ1
Han, CH1
Shim, BS1
Cho, YH1
Brueseke, TJ1
Lane, FL1
Ryu, JK1
Lee, SM1
Seong, DW1
Suh, JK1
Kim, S1
Choe, W1
Moon, Y1
Pai, SH1
Alexander, RB2
Propert, KJ2
Schaeffer, AJ2
Landis, JR2
Nickel, JC2
O'Leary, MP1
Pontari, MA1
McNaughton-Collins, M1
Shoskes, DA1
Comiter, CV1
Datta, NS1
Fowler, JE1
Nadler, RB1
Zeitlin, SI1
Knauss, JS1
Wang, Y1
Kusek, JW2
Nyberg, LM2
Litwin, MS2
Weidner, W1
Kulovac, B1
Aganović, D1
Prcić, A1
Hadziosmanović, O1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01843946]75 participants (Actual)Observational2011-03-31Completed
A Randomized Clinical Trial to Evaluate the Efficacy and Safety of 10mg Alfuzosin in the Treatment of Chronic Prostatitis / Chronic Pelvic Pain Syndrome (CP/CPPS) in Recently-Diagnosed and/or Newly-Symptomatic Alpha-blocker Naïve Patients[NCT00103402]Phase 3272 participants (Actual)Interventional2005-02-28Completed
Ciprofloxacin or Tamsulosin in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome: a Randomized, Double-blind Trial[NCT04552431]Phase 2196 participants (Actual)Interventional1997-09-30Completed
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)[NCT00499317]500 participants (Anticipated)Observational2007-01-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Hospital Anxiety and Depression Scale

For the Hospital Anxiety and Depression Scale, higher scores indicate greater anxiety and depression; range, 0 to 42. (NCT00103402)
Timeframe: Baseline and 12 weeks

Interventionunits on a scale (Mean)
Alfuzosin-2.6
Placebo-1.5

Change in International Index of Erectile Dysfunction (IIEF)

For the International Index of Erectile Function, higher scores indicate better sexual function; range, 0 to 75. (NCT00103402)
Timeframe: Baseline and 12 weeks

Interventionunits on a scale (Mean)
Alfuzosin0.5
Placebo-0.2

Change in Male Sexual Health Questionnaire

For the Male Sexual Health Questionnaire, higher scores indicate better function with respect to erection and ejaculation and greater satisfaction with sexual life; range, 0 to 40. (NCT00103402)
Timeframe: Baseline and 12 weeks

Interventionunits on a scale (Mean)
Alfuzosin1.7
Placebo0.6

Number of Participants With Decline in Total Score ≥4 for the NIH-CPSI Total Score From Baseline to 12 Weeks

For the National Institutes of Health Chronic Prostatitis Symptom Index (NIHCPSI) total score, higher scores indicate more severe symptoms and scores range from 0 to 43. The primary outcome was a decline of at least 4 from baseline to 12 weeks (NCT00103402)
Timeframe: Baseline and 12 weeks

InterventionParticipants (Count of Participants)
Alfuzosin68
Placebo66

Change in Medical Outcomes Study Short Form 12

For the Medical Outcomes Study Short Form Health Survey 12 (SF-12), higher scores indicate better quality of life. Score range for both the physical and mental component summaries is 0 to 100. (NCT00103402)
Timeframe: Baseline and 12 weeks

,
Interventionunits on a scale (Mean)
Physical componentMental component
Alfuzosin3.04.0
Placebo3.51.9

Change in Subscales of the McGill Pain Questionnaire

For the McGill Pain Questionnaire, higher scores indicate greater pain. Score ranges are as follows: total score, 0 to 45; sensory score, 0 to 33; affective score, 0 to 12. (NCT00103402)
Timeframe: Baseline and 12 weeks

,
Interventionunits on a scale (Mean)
Total scoreSensory scoreAffective score
Alfuzosin-3.4-2.5-1.0
Placebo-3.1-2.3-0.9

Change in Subscales of the NIH-CPSI

For the National Institutes of Health Chronic Prostatitis Symptom Index (NIHCPSI), higher scores indicate more severe symptoms (for the quality-of-life score, higher scores indicate a more negative effect). Score ranges are as follows: total score, 0 to 43; pain score, 0 to 21; urinary score, 0 to 10, quality-of-life score, 0 to 12; and average pain and urgency scores, 0 to 10. (NCT00103402)
Timeframe: Baseline and12 weeks

,
Interventionunits on a scale (Mean)
Total scorePain scoreUrinary scoreQuality-of-life score
Alfuzosin-7.1-3.3-1.2-1.2
Placebo-6.5-3.0-1.0-1.2

Trials

5 trials available for ciprofloxacin and Pelvic Pain

ArticleYear
Clinical efficacy of roxithromycin in men with chronic prostatitis/chronic pelvic pain syndrome in comparison with ciprofloxacin and aceclofenac: a prospective, randomized, multicenter pilot trial.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014, Volume: 20, Issue:1

    Topics: Adult; Chronic Disease; Ciprofloxacin; Diclofenac; Humans; Male; Pelvic Pain; Pilot Projects; Prospe

2014
Tc-99m ciprofloxacin imaging in diagnosis of chronic bacterial prostatitis.
    Asian journal of andrology, 2003, Volume: 5, Issue:3

    Topics: Adult; Aged; Bacterial Infections; Chronic Disease; Ciprofloxacin; Humans; Male; Middle Aged; Organo

2003
Ciprofloxacin or tamsulosin in men with chronic prostatitis/chronic pelvic pain syndrome: a randomized, double-blind trial.
    Annals of internal medicine, 2004, Oct-19, Volume: 141, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Double-B

2004
Management of chronic nonbacterial prostatitis/chronic pelvic pain syndrome.
    Bosnian journal of basic medical sciences, 2007, Volume: 7, Issue:3

    Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Doxazosin; Drug Therapy, Combination;

2007
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002
Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
    Urology, 2002, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Therapy, C

2002

Other Studies

3 other studies available for ciprofloxacin and Pelvic Pain

ArticleYear
Ischiorectal fossa abscess after pelvic floor injection of botulinum toxin.
    American journal of obstetrics and gynecology, 2012, Volume: 206, Issue:3

    Topics: Abscess; Ampicillin; Anti-Bacterial Agents; Anti-Dyskinesia Agents; Anus Diseases; Botulinum Toxins;

2012
Summaries for patients. Treating men with chronic prostatitis/chronic pelvic pain syndrome.
    Annals of internal medicine, 2004, Oct-19, Volume: 141, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Double-B

2004
Treating chronic prostatitis: antibiotics no, alpha-blockers maybe.
    Annals of internal medicine, 2004, Oct-19, Volume: 141, Issue:8

    Topics: Adrenergic alpha-Antagonists; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Humans; Male; P

2004