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ciprofloxacin and Neutropenia

ciprofloxacin has been researched along with Neutropenia in 157 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.

Research Excerpts

ExcerptRelevanceReference
"Fluoroquinolones reduce occurrence of fever in adult cancer patients who develop neutropenia, but there has been no randomized controlled trial in children, and there are only a few studies considering resistance in intestinal floral after ciprofloxacin has been used."9.17Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy. ( Chelae, S; Khwanna, T; Laoprasopwattana, K; Sujjanunt, T; Suwankeeree, P; Tunyapanit, W, 2013)
" The present study was designed to evaluate the benefit of intravenous ciprofloxacin for neutropenic patients with fever who were refractory to initial therapy given for the first 3 days."9.12Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy. ( Kawano, F; Koga, S; Matsuoka, H; Okamura, S; Shibata, K; Shirahashi, A; Suzushima, H; Tamura, K; Tsukamoto, A; Uozumi, K; Yamashita, K, 2006)
"The objective of this study was to test the efficacy of oral ciprofloxacin in the treatment of lower risk febrile neutropenia (LRFN) in children treated for malignant diseases."9.09Oral ciprofloxacin in the management of children with cancer with lower risk febrile neutropenia. ( Armada, A; Cáceres, E; Casimir, L; Debbag, R; Fernández, C; Firpo, V; Latella, A; Paganini, H; Rodriguez-Brieshcke, T; Zubizarreta, P, 2001)
"This intervention influenced administration of ciprofloxacin without apparent compromise of patient outcomes and resulted in a reduction in total costs of treating febrile neutropenia."9.09A new ciprofloxacin stepdown program in the treatment of high-risk febrile neutropenia: a clinical and economic analysis. ( de Lemos, ML; Frighetto, L; Jewesson, PJ; Marra, CA; Marra, F; Quaia, CB; Warkentin, DI, 2000)
"Low-risk patients (N = 70) with episodes of fever and neutropenia (N = 116) were randomized to receive either oral ciprofloxacin or intravenous ceftriaxone as outpatients."9.09Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial. ( Campos, MC; Dantas, LS; Ginani, VC; Petrilli, AS; Seber, A; Tanaka, C, 2000)
"We examined the efficacy of ciprofloxacin as an empirical treatment for fever in 97 neutropenic patients in a randomized study of ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin."9.06A comparative study of intravenous ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin for the empirical treatment of fever in neutropenic patients. ( Jenkins, GC; Kelsey, SM; Newland, AC; Shaw, E; Wood, ME, 1990)
"This study developed further clinical experience in using a single agent ("monotherapy") as empirical treatment for neutropenic patients with fever, and compared the safety and toxicity of two candidate agents, ceftazidime and ciprofloxacin."9.06A prospective, randomized comparison of ceftazidime and ciprofloxacin as initial empiric therapy in neutropenic patients with fever. ( Bayston, KF; Cohen, J; Want, S, 1989)
"To assess the efficacy of ciprofloxacin in neutropenic patients, we conducted a randomized prospective trial comparing the combination of ciprofloxacin and netilmicin against piperacillin plus netilmicin as an empiric treatment of fever in cancer patients with neutropenia."9.06Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients. ( Anderson, H; Chan, CC; Oppenheim, BA; Scarffe, JH; Swindell, R, 1989)
"We compared the combination of teicoplanin plus ciprofloxacin with gentamicin plus piperacillin for the empirical treatment of fever in 80 neutropenic patients."9.06A randomized study of teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin for the empirical treatment of fever in neutropenic patients. ( Collins, PW; Delord, C; Kelsey, SM; Newland, AC; Weinhard, B, 1990)
"To compare the effectiveness and toxicity of ciprofloxacin vs an aminoglycoside, both in combination with a beta-lactam, for the treatment of febrile neutropenia in the inpatient setting."8.82Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials. ( Bliziotis, IA; Christodoulou, C; Chrysanthopoulou, S; Falagas, ME; Kasiakou, SK; Michalopoulos, A; Samonis, G, 2005)
"In this retrospective study, we analyzed the clinical data and outcome of patients with AML who did or did not receive prophylactic ciprofloxacin 500 mg BD for neutropenic fever."7.83Prophylaxis of neutropenic fever with ciprofloxacin in patients with acute myeloid leukemia treated with intensive chemotherapy. ( Foratyazdi, M; Ghadiany, M; Mehdizadeh, M; Mohammad Alizadeh, A; Rahimi, H; Rezvani, H; Zamani, N, 2016)
"The objective of this investigation was to assess retrospectively the safety and the efficacy of oral ciprofloxacin plus cefuroxime axetil compared to the combination of oral ciprofloxacin plus amoxicillin/clavulanate, as initial outpatient treatment, in low-risk cancer patients with fever and neutropenia."7.74Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate. ( Karabelis, A; Kordossis, T; Kosmas, C; Sipsas, NV; Skopelitis, E; Tsavaris, N; Vadiaka, M; Ziakas, PD, 2007)
"The current results suggest that fluoroquinolone prophylaxis for patients with febrile neutropenia may be abandoned safely in areas with a high prevalence of ciprofloxacin-resistant enterobacteria."7.72Ciprofloxacin prophylaxis in patients with acute leukemia and granulocytopenia in an area with a high prevalence of ciprofloxacin-resistant Escherichia coli. ( Dalmau, D; Estany, C; Estrada, C; Garau, J; Gomez, L; Marquez, M; Martí, JM; Xercavins, M, 2003)
"The current study demonstrates that very carefully selected, low risk patients with febrile neutropenia may be treated successfully without hospitalization using oral ciprofloxacin."7.70Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer. ( Aquino, VM; Buchanan, GR; Herrera, L; Sandler, ES, 2000)
"Fifty consecutive episodes of neutropenia were studied in patients with AML who received prophylaxis with ciprofloxacin and these were compared with a historic control group of another 50 consecutive episodes of neutropenia in AML patients who did not receive antibiotic prophylaxis."7.69[Prophylaxis with ciprofloxacin in postchemotherapy neutropenia in acute myeloid leukemia]. ( Bueno, J; Juliá, A; López, A; Novo, A; Soler, JA, 1994)
"To assess the value of prophylactic ciprofloxacin in reducing the incidence of neutropenic fever in men receiving intensive chemotherapy for germ cell tumours, we reviewed the case notes of 88 consecutive patients treated between January 1986 and December 1992."7.69Chemotherapy for germ cell tumours: prophylactic ciprofloxacin reduces the incidence of neutropenic fever. ( Counsell, R; Pratt, J; Williams, MV, 1994)
"We studied the efficacy of piperacillin and ciprofloxacin as initial parenteral therapy in 41 adult patients with leukemia who developed 47 febrile episodes during severe neutropenia following chemotherapy."7.68A pilot study of piperacillin and ciprofloxacin as initial therapy for fever in severely neutropenic leukemia patients. ( Lerner, R; Nilsson, PG; Palmblad, J; Samuelsson, J; Wahlin, A; Winqvist, I, 1992)
"Inclusion criteria were cancer, febrile neutropenia, low risk of complications as predicted by a Multinational Association for Supportive Care in Cancer (MASCC) score > 20, ability to swallow, and ≤ one single intravenous dose of empiric antibiotic therapy before study drug treatment initiation."6.78Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectiou ( Akan, H; Akova, M; Aoun, M; Calandra, T; de Bock, R; Drgona, L; Kern, WV; Marchetti, O; Paesmans, M; Viscoli, C, 2013)
"Patients with stage T2-T4 primary breast cancer were scheduled to receive 6-8 cycles of TAC."6.73Pegfilgrastim +/- ciprofloxacin for primary prophylaxis with TAC (docetaxel/doxorubicin/cyclophosphamide) chemotherapy for breast cancer. Results from the GEPARTRIO study. ( Costa, SD; du Bois, A; Eidtmann, H; Eiermann, W; Gerber, B; Grasshoff, ST; Hilfrich, J; Huober, J; Jackisch, C; Kaufmann, M; Kümmel, S; Loibl, S; Mehta, KM; Skacel, T; Vescia, S; von Minckwitz, G, 2008)
"Pediatric cancer patients presenting with febrile neutropenia after non-myeloablative chemotherapy and who met institutional criteria for early hospital discharge following a minimum of 48-hr inpatient empiric intravenous ceftazidime were eligible for the study."6.71Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients. ( Burns, JL; Coughlin, J; Friedman, DL; Hawkins, D; Park, JR; Pendergrass, T, 2003)
"Ciprofloxacin was compared to ciprofloxacin plus amoxicillin as antibacterial prophylaxis in 53 evaluable patients with neutropenic episodes, because an oral penicillin may help to decrease the incidence of gram-positive infections."6.67Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin vs ciprofloxacin plus amoxicillin. ( Bosi, A; Ciolli, S; Donnini, E; Fanci, R; Guidi, S; Leoni, F; Longo, G; Rossi Ferrini, P, 1993)
"In a randomized study comparing cotrimoxazole plus colistin with ciprofloxacin, each in combination with nonabsorbable antimycotics, the incidence of major infections in terms of septicemias and pneumonias as well as of minor infections and episodes of unexplained fever (FUO) was higher in patients treated with ciprofloxacin."6.16Prevention of infection in acute leukemia. ( Daenen, S; de Pauw, BE; de Vries-Hospers, HG; Dekker, AW; Donnelly, JP; Gaus, W; Haralambie, E; Kern, W; Konrad, H; Maschmeyer, G, 1990)
"Bacteremia was documented in 33 patients (15."5.46Bacteremia during neutropenic episodes in children undergoing hematopoietic stem cell transplantation with ciprofloxacin and penicillin prophylaxis. ( Anurathapan, U; Choeyprasert, W; Hongeng, S; Pakakasama, S, 2017)
" Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0."5.35Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009)
"Unfortunately, neutropenia is common."5.31The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization. ( Andresen, SW; Avery, RK; Bernhard, L; Bolwell, BJ; Goormastic, M; Kalaycio, ME; Kuczkowski, E; Longworth, DL; Mossad, SB; Ostendorf, H; Pohlman, BL; Sobecks, RM; Wise, K, 2002)
"Fluoroquinolones reduce occurrence of fever in adult cancer patients who develop neutropenia, but there has been no randomized controlled trial in children, and there are only a few studies considering resistance in intestinal floral after ciprofloxacin has been used."5.17Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy. ( Chelae, S; Khwanna, T; Laoprasopwattana, K; Sujjanunt, T; Suwankeeree, P; Tunyapanit, W, 2013)
"Ciprofloxacin (CPFX) is a potential alternative in patients with febrile neutropenia (FN) because of its activity against Gram-negative organisms."5.17Randomized controlled trial comparing ciprofloxacin and cefepime in febrile neutropenic patients with hematological malignancies. ( Atsuta, Y; Emi, N; Inamoto, Y; Ishikawa, Y; Nagai, H; Naoe, T; Ozawa, Y; Ozeki, K; Suzuki, R; Terakura, S; Yanada, M; Yasuda, T, 2013)
" After a pre-intervention period, in which cefepime was used as the initial agent for febrile neutropenia, 4 primary antibiotics, namely, piperacillin-tazobactam, ciprofloxacin, meropenem, and cefepime, were rotated at 1-month intervals over 20 months."5.17Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity. ( Akashi, K; Chong, Y; Ito, Y; Kamimura, T; Miyamoto, T; Shimoda, S; Shimono, N; Yakushiji, H, 2013)
" The present study was designed to evaluate the benefit of intravenous ciprofloxacin for neutropenic patients with fever who were refractory to initial therapy given for the first 3 days."5.12Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy. ( Kawano, F; Koga, S; Matsuoka, H; Okamura, S; Shibata, K; Shirahashi, A; Suzushima, H; Tamura, K; Tsukamoto, A; Uozumi, K; Yamashita, K, 2006)
"An open-label randomised clinical trial was designed to compare the efficacy and tolerance of levofloxacin and ciprofloxacin plus phenethicillin for the prevention of bacterial infections in patients with high-risk neutropenia, and to monitor the emergence of antimicrobial resistance."5.12Levofloxacin vs. ciprofloxacin plus phenethicillin for the prevention of bacterial infections in patients with haematological malignancies. ( Huijgens, PC; Janssen, JJ; Leidekker, ME; Simoons-Smit, AM; Timmers, GJ; Vandenbroucke-Grauls, CM, 2007)
"To determine whether ciprofloxacin-piperacillin is equivalent to tobramycin-piperacillin as empirical therapy for neutropenic fever."5.10Ciprofloxacin plus piperacillin compared with tobramycin plus piperacillin as empirical therapy in febrile neutropenic patients. A randomized, double-blind trial. ( Cushing, DA; Donowitz, GR; Harman, CP; Haverstock, DC; Herrington, DA; Hurd, DD; Kowalsky, SF; Lazarus, HM; Peacock, JE; Reed, MD; Sinclair, JW; Wade, JC, 2002)
"Evaluation of benzylpenicillin (penicillin G) effect for infection prophylaxis at the oncological patients with severe postcytostatic neutropenia was performed."5.10[Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia]. ( Chimishkian, KL; Dmitrieva, NV; Larionova, VB; Minenko, SV; Ptushkin, VV; Sokolova, EN; Zhukov, NV, 2002)
"The objective of this study was to test the efficacy of oral ciprofloxacin in the treatment of lower risk febrile neutropenia (LRFN) in children treated for malignant diseases."5.09Oral ciprofloxacin in the management of children with cancer with lower risk febrile neutropenia. ( Armada, A; Cáceres, E; Casimir, L; Debbag, R; Fernández, C; Firpo, V; Latella, A; Paganini, H; Rodriguez-Brieshcke, T; Zubizarreta, P, 2001)
"This intervention influenced administration of ciprofloxacin without apparent compromise of patient outcomes and resulted in a reduction in total costs of treating febrile neutropenia."5.09A new ciprofloxacin stepdown program in the treatment of high-risk febrile neutropenia: a clinical and economic analysis. ( de Lemos, ML; Frighetto, L; Jewesson, PJ; Marra, CA; Marra, F; Quaia, CB; Warkentin, DI, 2000)
"To determine whether the addition of rifampin to a quinolone-based antibacterial prophylactic regimen in patients undergoing high-dose chemotherapy (HDC) with peripheral-blood stem-cell transplantation (PBSCT) decreases the incidence of neutropenia and fever, Gram-positive bacteremia, and infection-related morbidity."5.09Rifampin does not improve the efficacy of quinolone antibacterial prophylaxis in neutropenic cancer patients: results of a randomized clinical trial. ( Arcediano, A; Cortés-Funes, H; Gomez-Martin, C; Hidalgo, M; Hornedo, J; Lumbreras, C; Perea, S; Rodriguez, M; Salazar, R; Solá, C; Valentí, V, 2000)
"In hospitalized low-risk patients who have fever and neutropenia during cancer chemotherapy, empirical therapy with oral ciprofloxacin and amoxicillin-clavulanate is safe and effective."5.09A double-blind comparison of empirical oral and intravenous antibiotic therapy for low-risk febrile patients with neutropenia during cancer chemotherapy. ( Chanock, S; Freifeld, A; Gill, V; Hicks, JE; Hiemenz, J; Hiemenz, S; Lewis, L; Marchigiani, D; Pizzo, PA; Steinberg, SM; Walsh, T, 1999)
"Low-risk patients (N = 70) with episodes of fever and neutropenia (N = 116) were randomized to receive either oral ciprofloxacin or intravenous ceftriaxone as outpatients."5.09Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial. ( Campos, MC; Dantas, LS; Ginani, VC; Petrilli, AS; Seber, A; Tanaka, C, 2000)
"The objective of this study was to evaluate the efficacy of oral ciprofloxacin in preventing febrile morbidity superimposed on the neutropenia induced from a paclitaxel regimen in ovarian cancer patients."5.08Chemoprophylaxis with ciprofloxacin in ovarian cancer patients receiving paclitaxel: a randomized trial. ( Carlson, JW; Carson, LF; Copeland, LJ; Fowler, JM; Mayer, AR; Mitchell, SK, 1997)
"The purpose of this study was to test the comparative efficacy and toxicity of empiric gentamicin and ciprofloxacin, in combination with piperacillin, in febrile patients with treatment-induced neutropenia."5.08Ciprofloxacin plus piperacillin is an equally effective regimen for empiric therapy in febrile neutropenic patients compared with standard therapy. ( Betts, RF; Blair, EA; Flesher, WR; Griggs, JJ; Norton, JR; Rowe, JM, 1998)
"More patients receiving ciprofloxacin did not develop fever during neutropenia and did not receive antibiotics (34%) compared with those receiving norfloxacin (25%) (P = 0."5.07Prevention of bacterial infection in neutropenic patients with hematologic malignancies. A randomized, multicenter trial comparing norfloxacin with ciprofloxacin. The GIMEMA Infection Program. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto. ( , 1991)
"Teicoplanin plus ciprofloxacin was compared with gentamicin plus piperacillin for the empirical treatment of fever in 80 neutropenic patients."5.07Teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin in the treatment of febrile neutropenic patients. ( Collins, PW; Kelsey, SM; Newland, AC; Weinhardt, B, 1992)
"We studied the effectiveness of prophylactic oral ciprofloxacin and rifampin on fever prevention in patients undergoing autologous bone marrow transplantation (ABMT) for breast cancer."5.07Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support. ( Gilbert, C; Hussein, A; Meisenberg, B; Perfect, J; Peters, WP; Ross, M; Vredenburgh, J, 1994)
"This study developed further clinical experience in using a single agent ("monotherapy") as empirical treatment for neutropenic patients with fever, and compared the safety and toxicity of two candidate agents, ceftazidime and ciprofloxacin."5.06A prospective, randomized comparison of ceftazidime and ciprofloxacin as initial empiric therapy in neutropenic patients with fever. ( Bayston, KF; Cohen, J; Want, S, 1989)
"To assess the efficacy of ciprofloxacin in neutropenic patients, we conducted a randomized prospective trial comparing the combination of ciprofloxacin and netilmicin against piperacillin plus netilmicin as an empiric treatment of fever in cancer patients with neutropenia."5.06Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients. ( Anderson, H; Chan, CC; Oppenheim, BA; Scarffe, JH; Swindell, R, 1989)
"We examined the efficacy of ciprofloxacin as an empirical treatment for fever in 97 neutropenic patients in a randomized study of ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin."5.06A comparative study of intravenous ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin for the empirical treatment of fever in neutropenic patients. ( Jenkins, GC; Kelsey, SM; Newland, AC; Shaw, E; Wood, ME, 1990)
"We compared the combination of teicoplanin plus ciprofloxacin with gentamicin plus piperacillin for the empirical treatment of fever in 80 neutropenic patients."5.06A randomized study of teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin for the empirical treatment of fever in neutropenic patients. ( Collins, PW; Delord, C; Kelsey, SM; Newland, AC; Weinhard, B, 1990)
"In a multicenter, randomized clinical trial, the efficacy of ciprofloxacin plus azlocillin was compared with that of a standard regimen of ceftazidime plus amikacin for the initial empiric treatment of fever in neutropenic cancer patients."5.06Multicenter, randomized trial of ciprofloxacin plus azlocillin versus ceftazidime plus amikacin for empiric treatment of febrile neutropenic patients. ( Arnow, P; Edlin, B; Flaherty, JP; George, D; O'Keefe, P; Waitley, D; Weinstein, RA, 1989)
"To compare the effectiveness and toxicity of ciprofloxacin vs an aminoglycoside, both in combination with a beta-lactam, for the treatment of febrile neutropenia in the inpatient setting."4.82Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials. ( Bliziotis, IA; Christodoulou, C; Chrysanthopoulou, S; Falagas, ME; Kasiakou, SK; Michalopoulos, A; Samonis, G, 2005)
"A retrospective chart review was completed comparing the use of prophylactic moxifloxacin to that of levofloxacin or ciprofloxacin during periods of prolonged neutropenia."3.85Moxifloxacin versus levofloxacin or ciprofloxacin prophylaxis in acute myeloid leukemia patients receiving chemotherapy. ( Przybylski, DJ; Reeves, DJ, 2017)
"In this retrospective study, we analyzed the clinical data and outcome of patients with AML who did or did not receive prophylactic ciprofloxacin 500 mg BD for neutropenic fever."3.83Prophylaxis of neutropenic fever with ciprofloxacin in patients with acute myeloid leukemia treated with intensive chemotherapy. ( Foratyazdi, M; Ghadiany, M; Mehdizadeh, M; Mohammad Alizadeh, A; Rahimi, H; Rezvani, H; Zamani, N, 2016)
"We analyzed a cohort of 329 episodes of chemotherapy-induced neutropenia in adults, and compared two periods: 2005 (period 1, no prophylaxis, n=110) and 2006-2008 (period 2, ciprofloxacin prophylaxis, n=219)."3.79Ciprofloxacin prophylaxis in high risk neutropenic patients: effects on outcomes, antimicrobial therapy and resistance. ( Garnica, M; Maiolino, A; Moreira, BM; Nouér, SA; Nucci, M; Pellegrino, FL, 2013)
"This study seeks to determine the incidence of vancomycin-resistant enterococci (VRE) infection in high-risk neutropenic fever patients colonized with VRE and to determine patient characteristics associated with VRE infection."3.76Incidence of vancomycin-resistant enterococci (VRE) infection in high-risk febrile neutropenic patients colonized with VRE. ( Bossaer, JB; Garrett-Mayer, E; Hall, PD, 2010)
"The study confirms that oral ciprofloxacin and amoxicillin - clavulanate is a valuable alternative to the parenteral treatment combination in the management of NHL patients with chemotherapy-induced low risk febrile neutropenia."3.76[Oral antibiotics for non-Hodgkin's lymphoma patients with low risk neutropenic fever--a comparative controlled study]. ( Elis, A; Lishner, M; Manor, Y; Shacham-Abulafia, A, 2010)
" Neutropenia and thrombocytopenia associated with cefoxitin developed in 33 (51%) and 4 (6%) patients, respectively."3.75Antibiotic treatment of Mycobacterium abscessus lung disease: a retrospective analysis of 65 patients. ( Jeon, K; Kim, BJ; Kim, CK; Koh, WJ; Kook, YH; Kwon, OJ; Lee, NY; Lee, SH; Park, YK, 2009)
"The objective of this investigation was to assess retrospectively the safety and the efficacy of oral ciprofloxacin plus cefuroxime axetil compared to the combination of oral ciprofloxacin plus amoxicillin/clavulanate, as initial outpatient treatment, in low-risk cancer patients with fever and neutropenia."3.74Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate. ( Karabelis, A; Kordossis, T; Kosmas, C; Sipsas, NV; Skopelitis, E; Tsavaris, N; Vadiaka, M; Ziakas, PD, 2007)
"Of the 60 consecutive patients who received neoadjuvant chemotherapy as a phase II trial of docetaxel (60 mg/m(2)) and doxorubicin (50 mg/m(2)) for primary breast cancer, 30 low-risk febrile patients received oral ciprofloxacin."3.74The outpatient management of low-risk febrile patients with neutropenia: risk assessment over the telephone. ( Ando, M; Katsumata, N; Mizuno, T; Mukai, H; Shimizu, C; Watanabe, T, 2007)
"The current results suggest that fluoroquinolone prophylaxis for patients with febrile neutropenia may be abandoned safely in areas with a high prevalence of ciprofloxacin-resistant enterobacteria."3.72Ciprofloxacin prophylaxis in patients with acute leukemia and granulocytopenia in an area with a high prevalence of ciprofloxacin-resistant Escherichia coli. ( Dalmau, D; Estany, C; Estrada, C; Garau, J; Gomez, L; Marquez, M; Martí, JM; Xercavins, M, 2003)
"The current study demonstrates that very carefully selected, low risk patients with febrile neutropenia may be treated successfully without hospitalization using oral ciprofloxacin."3.70Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer. ( Aquino, VM; Buchanan, GR; Herrera, L; Sandler, ES, 2000)
" We evaluated retrospectively the effect of antibiotic prophylaxis with ciprofloxacin and penicillin on the prevention of bacterial infections in 112 cases of prolonged neutropenia in adult patients treated for haematological malignancies."3.70[Evaluation of antibiotic prophylaxis in neutropenic patients with hematologic malignancies]. ( Baumgartner, JD; Cometta, A; Delarive, P; Glauser, MP, 2000)
"To assess the value of prophylactic ciprofloxacin in reducing the incidence of neutropenic fever in men receiving intensive chemotherapy for germ cell tumours, we reviewed the case notes of 88 consecutive patients treated between January 1986 and December 1992."3.69Chemotherapy for germ cell tumours: prophylactic ciprofloxacin reduces the incidence of neutropenic fever. ( Counsell, R; Pratt, J; Williams, MV, 1994)
"Fifty consecutive episodes of neutropenia were studied in patients with AML who received prophylaxis with ciprofloxacin and these were compared with a historic control group of another 50 consecutive episodes of neutropenia in AML patients who did not receive antibiotic prophylaxis."3.69[Prophylaxis with ciprofloxacin in postchemotherapy neutropenia in acute myeloid leukemia]. ( Bueno, J; Juliá, A; López, A; Novo, A; Soler, JA, 1994)
"The objective of this study was to determine the efficacy and safety of the combination ciprofloxacin plus amoxicillin/clavulanic acid as an empirical treatment of infection in hematologic patients without severe neutropenia."3.69Sequential intravenous-oral ciprofloxacin plus amoxycillin/clavulanic acid shortens hospital stay in infected non severe neutropenic patients. ( Caballero, MD; Cañizo, MC; Colino, CI; Galende, J; García-Sanz, R; Gil-Hurlé, A; Hernández, JM; San Miguel, JF; Vallejo, C; Vázquez, L, 1997)
"We studied the efficacy of piperacillin and ciprofloxacin as initial parenteral therapy in 41 adult patients with leukemia who developed 47 febrile episodes during severe neutropenia following chemotherapy."3.68A pilot study of piperacillin and ciprofloxacin as initial therapy for fever in severely neutropenic leukemia patients. ( Lerner, R; Nilsson, PG; Palmblad, J; Samuelsson, J; Wahlin, A; Winqvist, I, 1992)
"Twenty-four episodes of fever in neutropenic patients with haematological malignancy were treated with ciprofloxacin."3.67Preliminary evaluation of ciprofloxacin, a new 4-quinolone antibiotic, in the treatment of febrile neutropenic patients. ( Farrell, ID; Geddes, AM; Leyland, MJ; Smith, GM, 1986)
"Forty-six episodes of fever in 34 patients with neutropenia and haematological malignancy were treated empirically with a combination of ciprofloxacin and vancomycin."3.67A clinical, microbiological and pharmacokinetic study of ciprofloxacin plus vancomycin as initial therapy of febrile episodes in neutropenic patients. ( Farrell, ID; Geddes, AM; Leyland, MJ; Smith, GM, 1988)
"Inclusion criteria were cancer, febrile neutropenia, low risk of complications as predicted by a Multinational Association for Supportive Care in Cancer (MASCC) score > 20, ability to swallow, and ≤ one single intravenous dose of empiric antibiotic therapy before study drug treatment initiation."2.78Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectiou ( Akan, H; Akova, M; Aoun, M; Calandra, T; de Bock, R; Drgona, L; Kern, WV; Marchetti, O; Paesmans, M; Viscoli, C, 2013)
"The standard treatment of fever in chemotherapy-induced neutropenia (FN) includes emergency hospitalization and empirical intravenous antimicrobial therapy."2.77First-day step-down to oral outpatient treatment versus continued standard treatment in children with cancer and low-risk fever in neutropenia. A randomized controlled trial within the multicenter SPOG 2003 FN study. ( Ammann, RA; Bodmer, N; Brack, E; Kühne, T; Leibundgut, K; Niggli, FK; Simon, A, 2012)
"Patients with stage T2-T4 primary breast cancer were scheduled to receive 6-8 cycles of TAC."2.73Pegfilgrastim +/- ciprofloxacin for primary prophylaxis with TAC (docetaxel/doxorubicin/cyclophosphamide) chemotherapy for breast cancer. Results from the GEPARTRIO study. ( Costa, SD; du Bois, A; Eidtmann, H; Eiermann, W; Gerber, B; Grasshoff, ST; Hilfrich, J; Huober, J; Jackisch, C; Kaufmann, M; Kümmel, S; Loibl, S; Mehta, KM; Skacel, T; Vescia, S; von Minckwitz, G, 2008)
" Daily assessments were made of all patients and all adverse events were recorded."2.73A prospective, controlled, randomized, non-blind, comparative study of the efficacy and safety of a once daily high dose of ceftriaxone plus ciprofloxacin versus thrice daily ceftazidime plus amikacin in empirical therapy for febrile neutropenic patients. ( Giannakakis, T; Hatzitolios, A; Kollaras, P; Kordosis, T; Metallidis, S; Nikolaidis, J; Nikolaidis, P; Seitanidis, B, 2008)
"We treated low-risk febrile neutropenic cancer patients utilizing two standard outpatient antibiotic pathways: oral ampicillin/clavulanate (500 mg) and ciprofloxacin (500 mg) or intravenous ceftazidime (2 g) and clindamycin (600 mg) every 8 h."2.71Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients. ( Badrina, N; Benjamin, R; DeJesus, Y; Escalante, CP; Fernandez, S; Ho, V; Lam, T; Lee, EL; Manzullo, E; Rivera, E; Rolston, K; Valdres, R; Weiser, MA, 2004)
"Neutropenic fever is one of the most serious adverse effects of cancer chemotherapy."2.71Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer. ( Goto, K; Kakinuma, R; Kubota, K; Matsumoto, T; Niho, S; Nishiwaki, Y; Ohe, Y; Ohmatsu, H, 2004)
"Pediatric cancer patients presenting with febrile neutropenia after non-myeloablative chemotherapy and who met institutional criteria for early hospital discharge following a minimum of 48-hr inpatient empiric intravenous ceftazidime were eligible for the study."2.71Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients. ( Burns, JL; Coughlin, J; Friedman, DL; Hawkins, D; Park, JR; Pendergrass, T, 2003)
"Only two Gram-negative bacterial infections occurred in the CIP + COL arm compared with 16 in the NEO + COL arm."2.70Oral ciprofloxacin plus colistin: prophylaxis against bacterial infection in neutropenic patients. A strategy for the prevention of emergence of antimicrobial resistance. ( Bhamra, A; Hann, IM; Kibbler, CC; Nazareth, B; Paterson, P; Prentice, HG, 2001)
"Ciprofloxacin was therefore superior to the other two fluoroquinolones in preventing infections due to Gram-negative bacteria in this population of neutropenic patients."2.67Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies. ( Accorsi, P; Betti, S; D'Antonio, D; Dell'Isola, M; Favalli, C; Fioritoni, G; Iacone, A; Parruti, G; Piccolomini, R; Quaglietta, AM, 1994)
"Ciprofloxacin was associated with a low incidence of adverse events with skin rash (five cases) and nausea (one case) being reported as possibly or probably related to ciprofloxacin."2.67High dose intravenous ciprofloxacin in febrile neutropenic patients. ( Johnson, PR; Tooth, JA; Yin, JA, 1990)
"There were five superinfections, all in the gentamicin/azlocillin group."2.67Randomized multicentre study of ciprofloxacin and azlocillin versus gentamicin and azlocillin in the treatment of febrile neutropenic patients. ( Barker, KF; Kaczmarski, RS; Mufti, GJ; Philpott-Howard, JN; Smedley, JC; Wade, JJ, 1990)
"Ciprofloxacin was compared to ciprofloxacin plus amoxicillin as antibacterial prophylaxis in 53 evaluable patients with neutropenic episodes, because an oral penicillin may help to decrease the incidence of gram-positive infections."2.67Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin vs ciprofloxacin plus amoxicillin. ( Bosi, A; Ciolli, S; Donnini, E; Fanci, R; Guidi, S; Leoni, F; Longo, G; Rossi Ferrini, P, 1993)
"Thus, up to date management of cancer patients, in addition to other supportive care modalities, should also incorporate diagnostic methods and therapy of infections."2.47[Treatment and prevention of infections in cancer patients with neutropenia]. ( Sinkó, J, 2011)
"Patients who are treated for acute leukemia should be offered prophylaxis with ciprofloxacin or levofloxacin."2.43Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. ( Bucaneve, G; Cullen, M; Fraser, A; Gafter-Gvili, A; Kern, WV; Leibovici, L; Paul, M, 2006)
"Allergic interstitial nephritis is believed to be the underlying pathological-process."2.38Ciprofloxacin-induced nephrotoxicity in patients with cancer. ( Bodey, GP; Lo, WK; Rolston, KV; Rubenstein, EB, 1993)
"Bacteremia was documented in 33 patients (15."1.46Bacteremia during neutropenic episodes in children undergoing hematopoietic stem cell transplantation with ciprofloxacin and penicillin prophylaxis. ( Anurathapan, U; Choeyprasert, W; Hongeng, S; Pakakasama, S, 2017)
"Treatment with voriconazole was promptly started with success."1.43Acute isolated appendicitis due to Aspergillus carneus in a neutropenic child with acute myeloid leukemia. ( Bergami, E; Cavanna, C; Decembrino, N; Introzzi, F; Lallitto, F; Mangione, F; Marone, P; Tamarozzi, F; Tortorano, AM; Zecca, M, 2016)
" One equivalent generic was selected for analysis by high-pressure liquid chromatography-tandem mass spectrometry (LC-MS/MS), to confirm chemical identity, and resistance selection experiments in a hollow-fiber (HF) system simulating two clinical dosing regimens."1.42Impact on resistance of the use of therapeutically equivalent generics: the case of ciprofloxacin. ( Agudelo, M; Rodriguez, CA; Vesga, O; Zuluaga, AF, 2015)
" Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0."1.35Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009)
"Ciprofloxacin (CIP) was the least active agent tested (MIC90 4 microg/ml; 86% susceptible)."1.31Emerging antimicrobial resistances among Proteus mirabilis in Europe: report from the MYSTIC Program (1997-2001). Meropenem Yearly Susceptibility Test Information Collection. ( Jones, RN; Mutnick, AH; Turner, PJ, 2002)
"Unfortunately, neutropenia is common."1.31The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization. ( Andresen, SW; Avery, RK; Bernhard, L; Bolwell, BJ; Goormastic, M; Kalaycio, ME; Kuczkowski, E; Longworth, DL; Mossad, SB; Ostendorf, H; Pohlman, BL; Sobecks, RM; Wise, K, 2002)
"Levofloxacin was somewhat more active against methicillin-resistant Staphylococcus aureus isolates."1.31Comparative in vitro activity of levofloxacin and ciprofloxacin against bacterial isolates from neutropenic patients. ( Catamo, G; D'Antonio, D; D'Ercole, S; Di Bonaventura, G; Piccolomini, R, 2002)
" Rats were also treated with E5 or B55 in combination with a suboptimal dose of ciprofloxacin at fever onset and again 24 h later."1.29Efficacy of anti-endotoxin monoclonal antibody E5 alone or in combination with ciprofloxacin in neutropenic rats with Pseudomonas sepsis. ( Opal, SM; Palardy, JE; Romulo, RL, 1993)
"Neutropenia was less severe (P < 0."1.29Prevention of bacteraemia by systemic ciprofloxacin treatment in rat cytomegalovirus-infected immunocompromised rats. ( Bruggeman, CA; Stals, FS; vd Bogaard, AE, 1994)
"Fleroxacin was inactive against S."1.28In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin. ( Beskid, G; Chan, K; Cleeland, R; Keith, DD; McGarry, CM; Siebelist, J, 1990)
"In ciprofloxacin-treated patients the flora were almost completely ciprofloxacin-resistant, whereas in the control groups resistant flora were detected only occasionally."1.28Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin. ( Huovinen, P; Kotilainen, P; Nikoskelainen, J, 1990)
"Ciprofloxacin was withdrawn from use in the unit and daily bathing with chlorhexidine gluconate solution started."1.28Outbreak of coagulase negative staphylococcus highly resistant to ciprofloxacin in a leukaemia unit. ( Burnie, JP; Hartley, JW; Lee, W; Oppenheim, BA, 1989)

Research

Studies (157)

TimeframeStudies, this research(%)All Research%
pre-199018 (11.46)18.7374
1990's61 (38.85)18.2507
2000's52 (33.12)29.6817
2010's25 (15.92)24.3611
2020's1 (0.64)2.80

Authors

AuthorsStudies
Forde, C1
McMullan, R1
Clarke, M1
Wilson, RH1
Plummer, R1
Grayson, M1
McDowell, C1
Agus, A1
Doran, A1
McAuley, DF1
Thomas, AL1
Barnes, RA1
Adams, R1
Chau, I1
Coyle, V1
Przybylski, DJ1
Reeves, DJ1
Wattier, RL1
Levy, ER1
Sabnis, AJ1
Dvorak, CC1
Auerbach, AD1
Castagnola, E1
Moroni, C1
Bandettini, R1
Caprino, D1
Haupt, R1
Garnica, M1
Nouér, SA1
Pellegrino, FL1
Moreira, BM1
Maiolino, A1
Nucci, M2
De Rosa, FG1
Motta, I1
Audisio, E1
Frairia, C1
Busca, A1
Di Perri, G1
Marmont, F1
Ghadiany, M1
Rahimi, H1
Rezvani, H1
Mohammad Alizadeh, A1
Zamani, N1
Mehdizadeh, M1
Foratyazdi, M1
Blennow, O1
Ljungman, P1
Sparrelid, E1
Mattsson, J1
Remberger, M1
Rodriguez, CA1
Agudelo, M1
Zuluaga, AF1
Vesga, O1
Mayer, K1
Hahn-Ast, C1
Mückter, S1
Schmitz, A1
Krause, S1
Felder, L1
Bekeredjian-Ding, I1
Molitor, E1
Brossart, P1
von Lilienfeld-Toal, M1
Petru, E1
Singer, CF1
Polterauer, S1
Galid, A1
Schauer, C1
Klocker, J1
Seifert, M1
Reinthaller, A1
Benedicic, C1
Hubalek, M1
Hefler, L1
Marth, C1
Scholl-Firon, T1
Bogner, G1
Zeimet, AG1
Decembrino, N1
Zecca, M1
Tortorano, AM1
Mangione, F1
Lallitto, F1
Introzzi, F1
Bergami, E1
Marone, P1
Tamarozzi, F1
Cavanna, C1
Flinn, A1
McDermott, M1
Butler, KM1
Pohlen, M1
Marx, J1
Mellmann, A1
Becker, K1
Mesters, RM1
Mikesch, JH1
Schliemann, C1
Lenz, G1
Müller-Tidow, C1
Büchner, T1
Krug, U1
Stelljes, M1
Karch, H1
Peters, G2
Gerth, HU1
Görlich, D1
Berdel, WE1
Choeyprasert, W1
Hongeng, S1
Anurathapan, U1
Pakakasama, S1
Metallidis, S1
Kollaras, P1
Giannakakis, T1
Seitanidis, B1
Kordosis, T1
Nikolaidis, J1
Hatzitolios, A1
Nikolaidis, P1
Jeon, K1
Kwon, OJ1
Lee, NY1
Kim, BJ1
Kook, YH1
Lee, SH1
Park, YK1
Kim, CK1
Koh, WJ1
Kitada, N1
Nishino, M1
Yasuda, J1
Morita, S1
Fujii, C1
Minegaki, T1
Kondoh, M1
Anami, S1
Takara, K1
Watari, M1
Upadya, GM1
Ruxana, K1
Bossaer, JB1
Hall, PD1
Garrett-Mayer, E1
Eleutherakis-Papaiakovou, E1
Kostis, E1
Migkou, M1
Christoulas, D1
Terpos, E1
Gavriatopoulou, M1
Roussou, M1
Bournakis, E1
Kastritis, E1
Efstathiou, E1
Dimopoulos, MA1
Papadimitriou, CA1
Shacham-Abulafia, A1
Elis, A1
Manor, Y1
Lishner, M1
Sinkó, J1
Brack, E1
Bodmer, N1
Simon, A1
Leibundgut, K1
Kühne, T1
Niggli, FK1
Ammann, RA2
Mullen, CA3
Laoprasopwattana, K1
Khwanna, T1
Suwankeeree, P1
Sujjanunt, T1
Tunyapanit, W1
Chelae, S1
Yasuda, T1
Suzuki, R1
Ishikawa, Y1
Terakura, S1
Inamoto, Y1
Yanada, M1
Nagai, H1
Ozawa, Y1
Ozeki, K1
Atsuta, Y1
Emi, N1
Naoe, T1
Slavin, MA1
Thursky, KA1
Kern, WV2
Marchetti, O1
Drgona, L1
Akan, H1
Aoun, M2
Akova, M1
de Bock, R1
Paesmans, M2
Viscoli, C1
Calandra, T1
Chong, Y1
Shimoda, S1
Yakushiji, H1
Ito, Y1
Miyamoto, T1
Kamimura, T1
Shimono, N1
Akashi, K1
Peacock, JE1
Herrington, DA1
Wade, JC1
Lazarus, HM1
Reed, MD1
Sinclair, JW1
Haverstock, DC1
Kowalsky, SF1
Hurd, DD1
Cushing, DA1
Harman, CP1
Donowitz, GR1
Mutnick, AH1
Turner, PJ1
Jones, RN1
Di Bonaventura, G1
D'Antonio, D5
Catamo, G1
D'Ercole, S1
Piccolomini, R3
Avery, RK1
Pohlman, BL1
Mossad, SB1
Goormastic, M1
Longworth, DL1
Kalaycio, ME1
Sobecks, RM1
Andresen, SW1
Kuczkowski, E1
Bernhard, L1
Ostendorf, H1
Wise, K1
Bolwell, BJ1
Park, JR1
Coughlin, J1
Hawkins, D1
Friedman, DL1
Burns, JL1
Pendergrass, T1
Zomorrodi, A1
Wald, ER1
Gowda, RV1
Stout, R1
Minenko, SV1
Dmitrieva, NV1
Chimishkian, KL1
Zhukov, NV1
Sokolova, EN1
Larionova, VB1
Ptushkin, VV1
Gomez, L1
Garau, J1
Estrada, C1
Marquez, M1
Dalmau, D1
Xercavins, M1
Martí, JM1
Estany, C1
Bodey, GP2
Rolston, KV3
Raad, II1
Linkin, DR1
Fishman, N1
Paganini, H3
Gómez, S1
Ruvinsky, S1
Zubizarreta, P3
Latella, A2
Fraquelli, L1
Iturres, AS1
Casimir, L2
Debbag, R2
Prabhu, RM1
Elliott, MA1
Patel, R1
Cometta, A2
Kern, W2
Niho, S1
Ohe, Y1
Goto, K1
Ohmatsu, H1
Matsumoto, T1
Kubota, K1
Kakinuma, R1
Nishiwaki, Y1
Escalante, CP1
Weiser, MA1
Manzullo, E2
Benjamin, R1
Rivera, E1
Lam, T1
Ho, V1
Valdres, R1
Lee, EL1
Badrina, N1
Fernandez, S1
DeJesus, Y1
Rolston, K2
Lalami, Y1
Munoz-Bermeo, R1
Reuss, K1
Cherifi, S1
Alexopoulos, CG1
Klastersky, J1
Rókusz, L1
László, L1
Paul, M2
Leibovici, L2
Bliziotis, IA1
Michalopoulos, A1
Kasiakou, SK1
Samonis, G1
Christodoulou, C1
Chrysanthopoulou, S1
Falagas, ME1
Timmer-Bonte, JN1
de Boo, TM1
Smit, HJ1
Biesma, B1
Wilschut, FA1
Cheragwandi, SA1
Termeer, A1
Hensing, CA1
Akkermans, J1
Adang, EM1
Bootsma, GP1
Tjan-Heijnen, VC2
Mizuno, T1
Katsumata, N1
Mukai, H1
Shimizu, C1
Ando, M1
Watanabe, T1
Matsuoka, H1
Tsukamoto, A1
Shirahashi, A1
Koga, S1
Suzushima, H1
Shibata, K1
Uozumi, K1
Yamashita, K1
Okamura, S1
Kawano, F1
Tamura, K1
Cullen, M1
Bucaneve, G3
Gafter-Gvili, A1
Fraser, A1
Patel, SM1
Saravolatz, LD1
Timmers, GJ1
Simoons-Smit, AM1
Leidekker, ME1
Janssen, JJ1
Vandenbroucke-Grauls, CM1
Huijgens, PC1
Sipsas, NV1
Kosmas, C1
Ziakas, PD1
Karabelis, A1
Vadiaka, M1
Skopelitis, E1
Kordossis, T1
Tsavaris, N1
von Minckwitz, G1
Kümmel, S1
du Bois, A1
Eiermann, W1
Eidtmann, H1
Gerber, B1
Hilfrich, J1
Huober, J1
Costa, SD1
Jackisch, C1
Grasshoff, ST1
Vescia, S1
Skacel, T1
Loibl, S1
Mehta, KM1
Kaufmann, M1
Elwood, ET1
Sommerville, DN1
Murray, JD1
Carlson, JW2
Fowler, JM2
Saltzman, AK1
Carter, JR1
Chen, MD1
Mitchell, SK2
Dunn, D1
Carson, LF2
Adcock, LL1
Twiggs, LB1
Velasco, E1
Costa, MA1
Martins, CA1
van Tiel, FH1
Slangen, BF1
Schouten, HC1
Jacobs, JA1
Ketley, NJ1
Kelsey, SM6
Newland, AC6
Stals, FS1
vd Bogaard, AE1
Bruggeman, CA1
Counsell, R1
Pratt, J1
Williams, MV1
Iacone, A3
Fioritoni, G3
Parruti, G1
Betti, S2
Quaglietta, AM1
Accorsi, P1
Dell'Isola, M2
Favalli, C1
López, A1
Soler, JA1
Juliá, A1
Novo, A1
Bueno, J1
Gilbert, C1
Meisenberg, B1
Vredenburgh, J1
Ross, M1
Hussein, A1
Perfect, J1
Peters, WP1
McWhinney, PH2
Patel, S1
Whiley, RA1
Hardie, JM1
Gillespie, SH1
Kibbler, CC3
Imrie, K1
Gold, W1
Salit, I1
Keating, A1
Romulo, RL1
Palardy, JE3
Opal, SM3
Del Favero, A3
Menichetti, F2
Rubenstein, EB2
Benjamin, RS1
Loewy, J1
Escalante, C1
Hughes, P1
Moreland, B1
Fender, A1
Kennedy, K1
Lo, WK1
Fanci, R1
Leoni, F1
Bosi, A1
Guidi, S1
Ciolli, S1
Longo, G1
Donnini, E1
Rossi Ferrini, P1
Cornelissen, JJ1
Rozenberg-Arska, M2
Dekker, AW2
Patrick, CC1
Freifeld, A2
Pizzo, P1
Horowitz, HW1
Holmgren, D1
Seiter, K1
Mani, V1
Cartwright, K1
Dooley, J1
Swarbrick, E1
Fairclough, P1
Oakley, C1
Hidalgo, M2
Hornedo, J2
Lumbreras, C2
Trigo, JM1
Gómez, C1
Perea, S2
Ruiz, A1
Hitt, R1
Cortés-Funes, H2
Mayer, AR1
Copeland, LJ1
Murphy, M1
Brown, AE1
Sepkowitz, KA1
Bernard, EM1
Kiehn, TE1
Armstrong, D1
Vallejo, C1
Caballero, MD1
García-Sanz, R1
Hernández, JM1
Vázquez, L1
Cañizo, MC1
Galende, J1
Colino, CI1
Gil-Hurlé, A1
San Miguel, JF1
Marie, JP1
Vekhoff, A1
Pico, JL1
Guy, H1
Andremont, A1
Richet, H1
Griggs, JJ1
Blair, EA1
Norton, JR1
Rowe, JM1
Flesher, WR1
Betts, RF1
Nouwen, JL1
van Belkum, A1
de Marie, S1
Sluijs, J1
Wielenga, JJ1
Kluytmans, JA1
Verbrugh, HA1
Jhung, JW1
Keith, JC1
Parejo, NA1
Young, LD1
Bhattacharjee, A1
Kerr, KG1
Armitage, HT1
von Eiff, C1
Minotti, V1
Gentile, G1
Iori, AP1
Micozzi, A2
Cavicchi, F1
Barbabietola, G1
Landonio, G2
Martino, P2
Petropoulos, D1
Roberts, WM1
Rytting, M1
Zipf, T1
Chan, KW1
Culbert, SJ1
Danielson, M1
Jeha, SS1
Kuttesch, JF1
Marchigiani, D1
Walsh, T1
Chanock, S1
Lewis, L1
Hiemenz, J1
Hiemenz, S1
Hicks, JE1
Gill, V1
Steinberg, SM1
Pizzo, PA1
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Bross, P1
Siegel, RS1
Small, CD1
Tabbara, IA1
Petrilli, AS1
Dantas, LS1
Campos, MC1
Tanaka, C1
Ginani, VC1
Seber, A1
Aquino, VM1
Herrera, L1
Sandler, ES1
Buchanan, GR1
Gomez-Martin, C1
Solá, C1
Valentí, V1
Arcediano, A1
Rodriguez, M1
Salazar, R1
Markman, M1
Kennedy, A1
Webster, K1
Peterson, G1
Kulp, B1
Belinson, J1
Marra, CA1
Frighetto, L1
Quaia, CB1
de Lemos, ML1
Warkentin, DI1
Marra, F1
Jewesson, PJ1
Rocchetta, HL1
Boylan, CJ1
Foley, JW1
Iversen, PW1
LeTourneau, DL1
McMillian, CL1
Contag, PR1
Jenkins, DE1
Parr, TR1
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Baumgartner, JD1
Glauser, MP1
Persson, L1
Vikerfors, T1
Sjöberg, L1
Engervall, P1
Tidefelt, U1
Rodriguez-Brieshcke, T1
Firpo, V1
Armada, A1
Fernández, C1
Cáceres, E1
Orlando, R1
Mastrullo, L1
De Blasi, D1
Boffa, ML1
Zorzato, G1
Miraglia, E1
Zaidi, Y1
Hastings, M1
Murray, J1
Hassan, R1
Kurshid, M1
Mahendra, P1
Prentice, HG1
Hann, IM1
Nazareth, B1
Paterson, P1
Bhamra, A1
Bunn, PA1
Postmus, PE1
Ardizzoni, A1
Lee, DG1
Choi, SM1
Choi, JH1
Yoo, JH1
Park, YH1
Kim, YJ1
Lee, S1
Min, CK1
Kim, HJ1
Kim, DW1
Lee, JW1
Min, WS1
Shin, WS1
Kim, CC1
Weinhardt, B1
Collins, PW2
Johnson, PR2
Liu Yin, JA1
Tooth, JA2
Samuelsson, J1
Nilsson, PG1
Wahlin, A1
Lerner, R1
Winqvist, I1
Palmblad, J1
Pizzigallo, E1
Piergallini, A1
Di Gianfilippo, R1
Olioso, P1
Torlontano, G1
Broughton, BJ1
Drusano, GL1
Wimperis, JZ2
Baglin, TP2
Marcus, RE1
Warren, RE2
Hyatt, DS1
Rogers, TR1
McCarthy, DM1
Samson, DS1
Collins, MS1
Ladehoff, D1
Mehton, NS1
Di Girolamo, A1
Cellini, L1
Nicoletti, M1
Villanueva Marcos, JL1
Villar Ráez, A1
Kindelán Jaquotot, JM1
Jurado Jiménez, R1
Pons, M1
del Blanco, J1
Mateo, L1
Juanola, X1
Beskid, G1
Siebelist, J1
McGarry, CM1
Cleeland, R1
Chan, K1
Keith, DD1
Maschmeyer, G1
Daenen, S1
de Pauw, BE1
de Vries-Hospers, HG1
Donnelly, JP1
Gaus, W1
Haralambie, E1
Konrad, H1
Moriuchi, Y1
Kamihira, S1
Yamamura, M1
Mori, H1
Miyazaki, Y1
Tokunaga, S1
Nonaka, H1
Amagasaki, T1
Yamada, Y1
Yoshida, Y1
Cross, AS1
Kelly, NM1
Sadoff, JC1
Bodmer, MW1
Victor, GH1
Lewin, CS1
Paton, R1
Amyes, SG1
Delord, C1
Weinhard, B1
Lim, SH1
Smith, MP1
Goldstone, AH1
Machin, SJ1
Wood, ME2
Shaw, E2
Jenkins, GC1
Arning, M1
Wolf, HH1
Aul, C1
Heyll, A1
Scharf, RE1
Scheider, W1
Yin, JA1
Constantine, CE1
Marcus, R1
Philpott-Howard, JN1
Barker, KF1
Wade, JJ1
Kaczmarski, RS1
Smedley, JC1
Mufti, GJ1
Kotilainen, P1
Nikoskelainen, J1
Huovinen, P1
Oppenheim, BA2
Hartley, JW1
Lee, W1
Burnie, JP1
Minetti, B1
Ricci, P1
Montillo, M1
Malleo, C1
Chan, CC1
Anderson, H1
Swindell, R1
Scarffe, JH1
Obana, Y1
Nishino, T1
Bayston, KF1
Want, S1
Cohen, J1
Flaherty, JP1
Waitley, D1
Edlin, B1
George, D1
Arnow, P1
O'Keefe, P1
Weinstein, RA1
Patton, WN1
Smith, GM3
Leyland, MJ3
Geddes, AM3
Chin, NX1
Jules, K1
Neu, HC1
Bendig, JW1
Kyle, PW1
Giangrande, PL1
Samson, DM1
Azadian, BS1
Verhoef, J1
Dekker, A1
Peterson, LR1
Moody, JA1
Fasching, CE1
Gerding, DN1
Mannan, P1
Noone, P1
Gordin, FM1
Hackbarth, CJ1
Scott, KG1
Sande, MA1
Trautmann, M1
Brückner, O1
Marre, R1
Hahn, H1
Farrell, ID2
Fu, KP1
Hetzel, N1
Gregory, FJ1
Hung, PP1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility Study of the Use of Intermediate Doses of Cytarabine Associated With Autologous Hematopoietic Stem Cells as Consolidation Treatment of Young Adults With Low- or Intermediate-risk de Novo Acute Myeloid Leukemia[NCT03023384]547 participants (Anticipated)Observational [Patient Registry]2016-12-31Recruiting
A Prospective Multi-Center Study on Pediatric Patients With Fever in Severe Chemotherapy Induced Neutropenia, Including a Randomized Comparison of Outpatient Management and Oral Antimicrobial Therapy Versus Inpatient Management and Intravenous Antimicrobi[NCT00107081]Phase 370 participants (Actual)Interventional2004-01-31Terminated (stopped due to Accrual goal for interventional part not achievable)
Randomized Controlled Trial Comparing Ciprofloxacin With Cefepime in Febrile Neutropenic Patients With Hematologic Diseases[NCT00137787]Phase 351 participants (Actual)Interventional2005-04-30Completed
Oral Empirical Therapy of Fever in Low-Risk Neutropenic Cancer Patients: A Prospective, Double-Blind, Randomized, Multicenter Trial Comparing Monotherapy (Single Daily Dose Moxifloxacin) With Combination Therapy (Ciprofloxacin Plus Amoxicillin/Clavulanic [NCT00062231]351 participants (Actual)Interventional2002-04-30Terminated (stopped due to low accrual)
Intermittent Every Other Days of 5 Shot-filgrastim Compared With Single Pegfilgrastim in Breast Cancer Patients Receiving Adjuvant Docetaxel, Doxorubicin, and Cyclophosphamide Chemotherapy (Intermittent G-CSF 105)[NCT02685111]Phase 222 participants (Actual)Interventional2016-02-29Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for ciprofloxacin and Neutropenia

ArticleYear
Prophylactic long-acting granulocyte-colony stimulating factors (G-CSF) in gynecologic malignancies: an oncologic expert statement.
    Wiener medizinische Wochenschrift (1946), 2015, Volume: 165, Issue:19-20

    Topics: Cause of Death; Ciprofloxacin; Contraindications; Delayed-Action Preparations; Disease Progression;

2015
[Treatment and prevention of infections in cancer patients with neutropenia].
    Magyar onkologia, 2011, Volume: 55, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Bacterial In

2011
Ecthyma gangrenosum: considerations in a previously healthy child.
    The Pediatric infectious disease journal, 2002, Volume: 21, Issue:12

    Topics: Administration, Oral; Chronic Disease; Ciprofloxacin; Ecthyma; Female; Follow-Up Studies; Granulocyt

2002
Ciprofloxacin in treatment of fever and neutropenia in pediatric cancer patients.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:12

    Topics: Ambulatory Care; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Bacterial I

2003
[Treatment with oral antibiotics of febrile neutropenia in onco-haematology. The experience of the EORTC antimicrobial group].
    Presse medicale (Paris, France : 1983), 2004, Mar-13, Volume: 33, Issue:5

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Bacterial Infections; Ceftazidi

2004
Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Therapy, Combination; Feve

2005
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
    Cancer, 2006, Oct-15, Volume: 107, Issue:8

    Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciproflox

2006
Monotherapy versus combination therapy.
    The Medical clinics of North America, 2006, Volume: 90, Issue:6

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Infections; Cellulit

2006
Ciprofloxacin-induced nephrotoxicity in patients with cancer.
    Archives of internal medicine, 1993, May-24, Volume: 153, Issue:10

    Topics: Acute Kidney Injury; Aged; Ciprofloxacin; Female; Fever; Humans; Kidney; Male; Middle Aged; Neoplasm

1993
Prevention of infection in acute leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Acute Disease; Anti-Bacterial Agents; Ciprofloxacin; Colistin; Drug Therapy, Combination; Humans; In

1990
Prevention of infection by ciprofloxacin in neutropenia.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl F

    Topics: Ciprofloxacin; Erythromycin; Feces; Gram-Negative Bacteria; Humans; Neutropenia; Sepsis; Staphylococ

1990

Trials

61 trials available for ciprofloxacin and Neutropenia

ArticleYear
Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis (the EASI-SWITCH trial): study protocol for a randomised controlled trial.
    Trials, 2020, May-27, Volume: 21, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; An

2020
A prospective, controlled, randomized, non-blind, comparative study of the efficacy and safety of a once daily high dose of ceftriaxone plus ciprofloxacin versus thrice daily ceftazidime plus amikacin in empirical therapy for febrile neutropenic patients.
    European journal of internal medicine, 2008, Volume: 19, Issue:8

    Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ceftazidime; Ceftriaxo

2008
[Equalization of breast cancer chemotherapy at general hospital( II )-evaluation of safety in FEC and TC regimens].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Ciprofloxa

2009
Prophylactic antibiotics for the prevention of neutropenic fever in patients undergoing autologous stem-cell transplantation: results of a single institution, randomized phase 2 trial.
    American journal of hematology, 2010, Volume: 85, Issue:11

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Ciprofloxacin; Fever; Graft Survival; Hematologic Neo

2010
First-day step-down to oral outpatient treatment versus continued standard treatment in children with cancer and low-risk fever in neutropenia. A randomized controlled trial within the multicenter SPOG 2003 FN study.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:3

    Topics: Administration, Oral; Adolescent; Ambulatory Care; Amoxicillin; Anti-Bacterial Agents; Antineoplasti

2012
Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:3

    Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agen

2013
Randomized controlled trial comparing ciprofloxacin and cefepime in febrile neutropenic patients with hematological malignancies.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Algorithms; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin;

2013
Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectiou
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Mar-20, Volume: 31, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Ag

2013
Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; Cefepime;

2013
Ciprofloxacin plus piperacillin compared with tobramycin plus piperacillin as empirical therapy in febrile neutropenic patients. A randomized, double-blind trial.
    Annals of internal medicine, 2002, Jul-16, Volume: 137, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bone Marrow Transplant

2002
Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients.
    Medical and pediatric oncology, 2003, Volume: 40, Issue:2

    Topics: Administration, Oral; Ambulatory Care; Amoxicillin; Antineoplastic Agents; Blood Cell Count; Child;

2003
[Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:7

    Topics: Adolescent; Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial I

2002
Outpatient, sequential, parenteral-oral antibiotic therapy for lower risk febrile neutropenia in children with malignant disease: a single-center, randomized, controlled trial in Argentina.
    Cancer, 2003, Apr-01, Volume: 97, Issue:7

    Topics: Administration, Oral; Adolescent; Ambulatory Care; Amikacin; Anti-Bacterial Agents; Antineoplastic A

2003
Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:2

    Topics: Administration, Oral; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ce

2004
Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:9

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Ampicillin; Anti-Bacterial Agents; Cancer Care Facilities;

2004
A prospective randomised evaluation of G-CSF or G-CSF plus oral antibiotics in chemotherapy-treated patients at high risk of developing febrile neutropenia.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:10

    Topics: Administration, Oral; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Age

2004
Prevention of chemotherapy-induced febrile neutropenia by prophylactic antibiotics plus or minus granulocyte colony-stimulating factor in small-cell lung cancer: a Dutch Randomized Phase III Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combin

2005
Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:8

    Topics: Adult; Aged; Algorithms; Carbapenems; Cefepime; Cephalosporins; Ciprofloxacin; Female; Fever; Hemato

2006
Levofloxacin vs. ciprofloxacin plus phenethicillin for the prevention of bacterial infections in patients with haematological malignancies.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2007, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ciprofloxacin; Cross Infecti

2007
Pegfilgrastim +/- ciprofloxacin for primary prophylaxis with TAC (docetaxel/doxorubicin/cyclophosphamide) chemotherapy for breast cancer. Results from the GEPARTRIO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxacin; Cyclop

2008
Randomized trial comparing oral ciprofloxacin plus penicillin V with amikacin plus carbenicillin or ceftazidime for empirical treatment of febrile neutropenic cancer patients.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Administration, Oral; Adult; Amikacin; Carbenicillin; Ceftazidime; Ciprofloxacin; Costs and Cost Ana

1995
Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Anti-Infective Agents; Bacteremia; Bacterial Infections; Ciprofloxacin

1994
Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; B

1994
Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer.
    Cancer, 1993, Jun-01, Volume: 71, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ambulatory Care; Aztreonam; Bacteremia; Bacterial Inf

1993
Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin vs ciprofloxacin plus amoxicillin.
    Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Amoxicillin; Bacteria; Bacterial Infections; Ciprofloxacin

1993
Discontinuation of intravenous antibiotic therapy during persistent neutropenia in patients receiving prophylaxis with oral ciprofloxacin.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:5

    Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Fever of Unknown

1995
Stepdown single agent antibiotic therapy for the management of the high risk neutropenic adult with hematologic malignancies.
    Leukemia & lymphoma, 1996, Volume: 23, Issue:1-2

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciproflo

1996
Lack of ability of ciprofloxacin-rifampin prophylaxis to decrease infection-related morbidity in neutropenic patients given cytotoxic therapy and peripheral blood stem cell transplants.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antineoplastic Com

1997
Chemoprophylaxis with ciprofloxacin in ovarian cancer patients receiving paclitaxel: a randomized trial.
    Gynecologic oncology, 1997, Volume: 65, Issue:2

    Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Bacteri

1997
Neutropenic infections: a review of the French Febrile Aplasia Study Group trials in 608 febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl D

    Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Therapy, Combinati

1998
Ciprofloxacin plus piperacillin is an equally effective regimen for empiric therapy in febrile neutropenic patients compared with standard therapy.
    American journal of hematology, 1998, Volume: 58, Issue:4

    Topics: Adult; Amphotericin B; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Female; Fever

1998
Domiciliary treatment of febrile episodes in cancer patients: a prospective randomized trial comparing oral versus parenteral empirical antibiotic treatment.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; C

1999
Outpatient treatment of fever and neutropenia for low risk pediatric cancer patients.
    Cancer, 1999, Jul-01, Volume: 86, Issue:1

    Topics: Adolescent; Ambulatory Care; Antineoplastic Agents; Bacterial Infections; Ceftazidime; Cephalosporin

1999
A double-blind comparison of empirical oral and intravenous antibiotic therapy for low-risk febrile patients with neutropenia during cancer chemotherapy.
    The New England journal of medicine, 1999, Jul-29, Volume: 341, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Antineoplastic Ag

1999
Empiric antimicrobial therapy of febrile neutropenic patients undergoing haematopoietic stem cell transplantation.
    International journal of antimicrobial agents, 1999, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Bone Marrow Transplantation; C

1999
Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial.
    Medical and pediatric oncology, 2000, Volume: 34, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Anti-Infective Agents; Antineoplastic Agen

2000
Rifampin does not improve the efficacy of quinolone antibacterial prophylaxis in neutropenic cancer patients: results of a randomized clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:10

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antineoplastic Age

2000
A new ciprofloxacin stepdown program in the treatment of high-risk febrile neutropenia: a clinical and economic analysis.
    Pharmacotherapy, 2000, Volume: 20, Issue:8

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Ciprofloxacin; Costs and Cost Analysis; Female;

2000
Oral ciprofloxacin in the management of children with cancer with lower risk febrile neutropenia.
    Cancer, 2001, Apr-15, Volume: 91, Issue:8

    Topics: Administration, Oral; Adolescent; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antineopla

2001
Oral ciprofloxacin plus colistin: prophylaxis against bacterial infection in neutropenic patients. A strategy for the prevention of emergence of antimicrobial resistance.
    British journal of haematology, 2001, Volume: 115, Issue:1

    Topics: Adolescent; Adult; Aged; Antibiotic Prophylaxis; Bacterial Infections; Bone Marrow Transplantation;

2001
Selective bowel decontamination for the prevention of infection in acute myelogenous leukemia: a prospective randomized trial.
    The Korean journal of internal medicine, 2002, Volume: 17, Issue:1

    Topics: Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciprofloxacin; Drug Ther

2002
Teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin in the treatment of febrile neutropenic patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:6

    Topics: Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fever; Gentamicins; Glycopeptides; H

1992
A randomized trial of high-dose ciprofloxacin versus azlocillin and netilmicin in the empirical therapy of febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1992, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Azlocillin; Ciprofloxacin; Double-Blind Method; Drug Therapy, Combination;

1992
A randomized trial of ciprofloxacin plus azlocillin versus netilmicin plus azlocillin for the empirical treatment of fever in neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1991, Volume: 28, Issue:2

    Topics: Azlocillin; Ciprofloxacin; Drug Therapy, Combination; Fever; Gram-Negative Bacterial Infections; Gra

1991
Clinical efficacy and in vitro activity of the ciprofloxacin-azlocillin combination (ratio 1:10) against gram-negative bacteria from non-neutropenic haematologic patients.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:9

    Topics: Adult; Aged; Azlocillin; Ciprofloxacin; Drug Therapy, Combination; Female; Gram-Negative Bacteria; G

1991
Prevention of bacterial infection in neutropenic patients with hematologic malignancies. A randomized, multicenter trial comparing norfloxacin with ciprofloxacin. The GIMEMA Infection Program. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto.
    Annals of internal medicine, 1991, Jul-01, Volume: 115, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fever;

1991
Prevention of infection in acute leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Acute Disease; Anti-Bacterial Agents; Ciprofloxacin; Colistin; Drug Therapy, Combination; Humans; In

1990
[Comparison of ciprofloxacin with polymyxin B for infection prophylaxis in neutropenic patients with acute non-lymphocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:10

    Topics: Administration, Inhalation; Administration, Oral; Bacterial Infections; Ciprofloxacin; Drug Administ

1990
Assessment of the interaction between ciprofloxacin and teicoplanin in vitro and in neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:4

    Topics: Adult; Ciprofloxacin; Drug Therapy, Combination; Glycopeptides; Humans; Methicillin Resistance; Midd

1990
A randomized study of teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin for the empirical treatment of fever in neutropenic patients.
    British journal of haematology, 1990, Volume: 76 Suppl 2

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bone Marrow Transplantation; Ciprofloxacin; D

1990
A randomized prospective study of ceftazidime and ciprofloxacin with or without teicoplanin as an empiric antibiotic regimen for febrile neutropenic patients.
    British journal of haematology, 1990, Volume: 76 Suppl 2

    Topics: Anti-Bacterial Agents; Bacteria; Catheterization, Peripheral; Ceftazidime; Ciprofloxacin; Drug Thera

1990
A comparative study of intravenous ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin for the empirical treatment of fever in neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:1

    Topics: Adult; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fever; Humans; Injections, In

1990
Infection prophylaxis in neutropenic patients with acute leukaemia--a randomized, comparative study with ofloxacin, ciprofloxacin and co-trimoxazole/colistin.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl D

    Topics: Bacterial Infections; Ciprofloxacin; Colistin; Humans; Neutropenia; Ofloxacin; Precursor Cell Lympho

1990
High dose intravenous ciprofloxacin in febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl F

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Ciprofloxacin; Female; Fever; Gram-Negative Bacteria;

1990
Randomized multicentre study of ciprofloxacin and azlocillin versus gentamicin and azlocillin in the treatment of febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl F

    Topics: Adolescent; Adult; Azlocillin; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Femal

1990
[Prophylaxis using quinolones in neutropenic patients. Preliminary results of a cooperative study by the Grupo Italiano Malattie Ematologiche maligne dell'adulto (GIMEMEA)].
    Haematologica, 1989, Volume: 74, Issue:5 Suppl

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Bone Marrow Transplantation; Ciproflox

1989
Intravenous ciprofloxacin as empirical treatment of febrile neutropenic patients.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adult; Agranulocytosis; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fe

1989
Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Bone Marrow Tr

1989
A prospective, randomized comparison of ceftazidime and ciprofloxacin as initial empiric therapy in neutropenic patients with fever.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adolescent; Adult; Agranulocytosis; Bacterial Infections; Ceftazidime; Ciprofloxacin; Female; Fever;

1989
Multicenter, randomized trial of ciprofloxacin plus azlocillin versus ceftazidime plus amikacin for empiric treatment of febrile neutropenic patients.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Amikacin; Azlocillin; Bacterial Infections; Ceftazi

1989
Prevention of infection in patients with acute nonlymphocytic leukemia by several drug treatment regimens.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Clinical Trials as Topic; Colistin; Drug

1987

Other Studies

86 other studies available for ciprofloxacin and Neutropenia

ArticleYear
Moxifloxacin versus levofloxacin or ciprofloxacin prophylaxis in acute myeloid leukemia patients receiving chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:12

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ciprofloxacin; Clostridioides difficile;

2017
Reducing Second Gram-Negative Antibiotic Therapy on Pediatric Oncology and Hematopoietic Stem Cell Transplantation Services.
    Infection control and hospital epidemiology, 2017, Volume: 38, Issue:9

    Topics: Adolescent; Anti-Bacterial Agents; Antimicrobial Stewardship; beta-Lactams; Child; Child, Preschool;

2017
Ciprofloxacin prophylaxis in children with acute leukemia in an era of increasing antibiotic resistance.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:5

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Ciprofloxacin; Female; Fever; Humans; Male; Neutropeni

2013
Ciprofloxacin prophylaxis in high risk neutropenic patients: effects on outcomes, antimicrobial therapy and resistance.
    BMC infectious diseases, 2013, Jul-31, Volume: 13

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremi

2013
Epidemiology of bloodstream infections in patients with acute myeloid leukemia undergoing levofloxacin prophylaxis.
    BMC infectious diseases, 2013, Dec-01, Volume: 13

    Topics: Adult; Aged; Antibiotic Prophylaxis; Bacteremia; Bacteria; Bacterial Infections; Ciprofloxacin; Fema

2013
Prophylaxis of neutropenic fever with ciprofloxacin in patients with acute myeloid leukemia treated with intensive chemotherapy.
    Asia-Pacific journal of clinical oncology, 2016, Volume: 12, Issue:1

    Topics: Adolescent; Aged; Antibiotic Prophylaxis; Ciprofloxacin; Female; Fever; Humans; Incidence; Induction

2016
Incidence, risk factors, and outcome of bloodstream infections during the pre-engraftment phase in 521 allogeneic hematopoietic stem cell transplantations.
    Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Amphotericin B; Anti-Infective Agents; Bacteremia; Candidiasis; Child; Chil

2014
Impact on resistance of the use of therapeutically equivalent generics: the case of ciprofloxacin.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drugs, Generic; Mice; Microbial Sensitivity Tests; Ne

2015
Comparison of antibiotic prophylaxis with cotrimoxazole/colistin (COT/COL) versus ciprofloxacin (CIP) in patients with acute myeloid leukemia.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial Infecti

2015
Acute isolated appendicitis due to Aspergillus carneus in a neutropenic child with acute myeloid leukemia.
    The new microbiologica, 2016, Volume: 39, Issue:1

    Topics: Acute Disease; Acyclovir; Amphotericin B; Antifungal Agents; Appendicitis; Aspergillosis; Aspergillu

2016
A Child With Septic Shock and Purpura.
    JAMA pediatrics, 2016, Volume: 170, Issue:4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Diagnosis, Differential; Drug Therapy, Combination; Female; Hu

2016
Ciprofloxacin versus colistin prophylaxis during neutropenia in acute myeloid leukemia: two parallel patient cohorts treated in a single center.
    Haematologica, 2016, Volume: 101, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineopl

2016
Bacteremia during neutropenic episodes in children undergoing hematopoietic stem cell transplantation with ciprofloxacin and penicillin prophylaxis.
    International journal of hematology, 2017, Volume: 105, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antilymphocyte Serum; Bacteremia; Child;

2017
Antibiotic treatment of Mycobacterium abscessus lung disease: a retrospective analysis of 65 patients.
    American journal of respiratory and critical care medicine, 2009, Nov-01, Volume: 180, Issue:9

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefoxitin; Chemical and Drug Induced

2009
Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:10

    Topics: Administration, Oral; Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Ciproflo

2009
Incidence of vancomycin-resistant enterococci (VRE) infection in high-risk febrile neutropenic patients colonized with VRE.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 19, Issue:2

    Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Case-Control Studies; Ciprofloxacin; Daptomycin; Ente

2010
[Oral antibiotics for non-Hodgkin's lymphoma patients with low risk neutropenic fever--a comparative controlled study].
    Harefuah, 2010, Volume: 149, Issue:6

    Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Antineoplastic Agents; Ciprofloxacin; Clav

2010
"Good enough" medicine: noninferiority clinical trials and the management of fever and neutropenia.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:3

    Topics: Ambulatory Care; Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Therapy, Combination; Femal

2012
Outpatient therapy for fever and neutropenia is safe but implementation is the key.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Mar-20, Volume: 31, Issue:9

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Female; Fev

2013
Summaries for patients. Treatment of fever in hospitalized patients with low white blood cell counts.
    Annals of internal medicine, 2002, Jul-16, Volume: 137, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bone Marrow Transplant

2002
Emerging antimicrobial resistances among Proteus mirabilis in Europe: report from the MYSTIC Program (1997-2001). Meropenem Yearly Susceptibility Test Information Collection.
    Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:3

    Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Critical Care; Cystic F

2002
Comparative in vitro activity of levofloxacin and ciprofloxacin against bacterial isolates from neutropenic patients.
    Chemotherapy, 2002, Volume: 48, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Neutropenia

2002
The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization.
    Bone marrow transplantation, 2002, Volume: 30, Issue:5

    Topics: Ambulatory Care; Antibiotic Prophylaxis; Cefepime; Cephalosporins; Ciprofloxacin; Clarithromycin; Da

2002
Pasteurella multocida infection in a post-chemotherapy neutropenic host following cat exposure.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2002, Volume: 14, Issue:6

    Topics: Aged; Animals; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas

2002
Ciprofloxacin prophylaxis in patients with acute leukemia and granulocytopenia in an area with a high prevalence of ciprofloxacin-resistant Escherichia coli.
    Cancer, 2003, Jan-15, Volume: 97, Issue:2

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Ciprofloxacin

2003
Ciprofloxacin versus tobramycin for neutropenic fevers.
    Annals of internal medicine, 2003, Mar-04, Volume: 138, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Fever; Human

2003
Ciprofloxacin versus tobramycin for neutropenic fevers.
    Annals of internal medicine, 2003, Mar-04, Volume: 138, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Fever; Human

2003
Apparent failure of moxifloxacin to prevent ciprofloxacin- and levofloxacin-susceptible Pseudomonas aeruginosa bacteremia in neutropenic patients undergoing peripheral blood stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Apr-01, Volume: 38, Issue:7

    Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Female; Fluoroquinolones; Hematopoi

2004
Outpatient, sequential, parenteral-oral antibiotic therapy for lower risk febrile neutropenia in children with malignant disease: a single-center, randomized, controlled trial in Argentina.
    Cancer, 2004, Apr-01, Volume: 100, Issue:7

    Topics: Anti-Bacterial Agents; Argentina; Ceftriaxone; Child; Ciprofloxacin; Humans; Neoplasms; Neutropenia;

2004
Infections of febrile neutropenic patients in malignant hematological diseases (second study period).
    Military medicine, 2005, Volume: 170, Issue:8

    Topics: Antibiotic Prophylaxis; Antineoplastic Agents; Bacteremia; Bacterial Infections; Ciprofloxacin; Fema

2005
Systematic reviews and meta-analysis of febrile neutropenia.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Therapy, Combination; Feve

2005
The outpatient management of low-risk febrile patients with neutropenia: risk assessment over the telephone.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007, Volume: 15, Issue:3

    Topics: Adult; Aged; Ambulatory Care; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols;

2007
Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate.
    Scandinavian journal of infectious diseases, 2007, Volume: 39, Issue:9

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Amoxicillin-Potassium Clavulanate Combination; A

2007
Periorbital necrotizing fasciitis.
    Plastic and reconstructive surgery, 2007, Volume: 120, Issue:7

    Topics: Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Breast Neoplasms;

2007
Chemoprophylaxis with oral ciprofloxacin in ovarian cancer patients receiving taxol.
    Gynecologic oncology, 1994, Volume: 55, Issue:3 Pt 1

    Topics: Administration, Oral; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bacteria

1994
Study of Stomatococcus mucilaginosus isolated in a hospital ward using phenotypic characterization.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1995, Volume: 14, Issue:3

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Cluster Analysis; Colony Count, Microbial; Cross Infection; Dr

1995
Teicoplanin and oral ciprofloxacin as outpatient treatment of infective episodes in patients with indwelling central venous catheters and haematological malignancy.
    Clinical and laboratory haematology, 1995, Volume: 17, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Bacterial Infections; Catheterization, Cen

1995
Prevention of bacteraemia by systemic ciprofloxacin treatment in rat cytomegalovirus-infected immunocompromised rats.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:1

    Topics: Animals; Bacteremia; Ciprofloxacin; Cytomegalovirus Infections; Gram-Negative Aerobic Bacteria; Gram

1994
Chemotherapy for germ cell tumours: prophylactic ciprofloxacin reduces the incidence of neutropenic fever.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1994, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carbo

1994
[Prophylaxis with ciprofloxacin in postchemotherapy neutropenia in acute myeloid leukemia].
    Medicina clinica, 1994, Jan-29, Volume: 102, Issue:3

    Topics: Adult; Aged; Bacterial Infections; Ciprofloxacin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mi

1994
Activities of potential therapeutic and prophylactic antibiotics against blood culture isolates of viridans group streptococci from neutropenic patients receiving ciprofloxacin.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:11

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Drug Synergism; Humans; Microbial

1993
Ciprofloxacin-induced neutropenia and erythema multiforme.
    American journal of hematology, 1993, Volume: 43, Issue:2

    Topics: Aged; Ciprofloxacin; Erythema Multiforme; Female; Humans; Neutropenia; Respiratory Tract Infections

1993
Efficacy of anti-endotoxin monoclonal antibody E5 alone or in combination with ciprofloxacin in neutropenic rats with Pseudomonas sepsis.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Bacteremia; Ciprofloxacin; Combined Modality Therapy; Endotoxins; F

1993
The new fluorinated quinolones for antimicrobial prophylaxis in neutropenic cancer patients.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A Suppl 1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Gram-Negativ

1993
Use of fluoroquinolones as prophylactic agents in patients with neutropenia.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:1

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciprofloxacin; Digestive System

1997
Use of fluoroquinolones for empirical management of febrile neutropenia in pediatric cancer patients.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:1

    Topics: Administration, Oral; Anti-Infective Agents; Child; Ciprofloxacin; Fever of Unknown Origin; Humans;

1997
Antibiotic prophylaxis in gastrointestinal endoscopy: a report by a Working Party for the British Society of Gastroenterology Endoscopy Committee.
    Endoscopy, 1997, Volume: 29, Issue:2

    Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophyla

1997
Fluoroquinolone prophylaxis for the prevention of bacterial infections in patients with cancer--is it justified?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Therapy; Ent

1997
Sequential intravenous-oral ciprofloxacin plus amoxycillin/clavulanic acid shortens hospital stay in infected non severe neutropenic patients.
    Hematology and cell therapy, 1997, Volume: 39, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Analysis of Variance;

1997
Clonal expansion of Staphylococcus epidermidis strains causing Hickman catheter-related infections in a hemato-oncologic department.
    Journal of clinical microbiology, 1998, Volume: 36, Issue:9

    Topics: Air Microbiology; Antibiotic Prophylaxis; Bacteriological Techniques; Catheterization, Central Venou

1998
Recombinant human interleukin-11 in experimental Pseudomonas aeruginosa sepsis in immunocompromised animals.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:4

    Topics: Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Com

1998
Activity of quinolones against viridans group streptococci isolated from blood cultures of patients with haematological malignancy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:1

    Topics: Adult; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Hematologic N

1999
In vitro activity of ciprofloxacin, ofloxacin, and levofloxacin against Micrococcus species and Stomatococcus mucilaginosus isolated from healthy subjects and neutropenic patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:12

    Topics: Anti-Infective Agents; Ciprofloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Human

1998
Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer.
    Cancer, 2000, Apr-01, Volume: 88, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Anti-Infective Agents; Blood Cell Count; C

2000
Experience with prophylactic oral ciprofloxacin in gynecological cancer patients developing severe chemotherapy-induced neutropenia.
    Journal of cancer research and clinical oncology, 2000, Volume: 126, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocol

2000
Validation of a noninvasive, real-time imaging technology using bioluminescent Escherichia coli in the neutropenic mouse thigh model of infection.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ceftazidime; Cell Count; Cephalosporins; Cipr

2001
[Evaluation of antibiotic prophylaxis in neutropenic patients with hematologic malignancies].
    Schweizerische medizinische Wochenschrift, 2000, Dec-02, Volume: 130, Issue:48

    Topics: Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial Infections; Ciprofloxacin; Dru

2000
Increased incidence of bacteraemia due to viridans streptococci in an unselected population of patients with acute myeloid leukaemia.
    Scandinavian journal of infectious diseases, 2000, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Antibiotic Prophylaxis;

2000
Aeromonas sobria sepsis in a neutropenic patient.
    Haematologica, 2001, Volume: 86, Issue:4

    Topics: Acute Disease; Aeromonas; Aged; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxaci

2001
Quinolone resistance in neutropenic patients: the effect of prescribing policy in the UK and Pakistan.
    Clinical and laboratory haematology, 2001, Volume: 23, Issue:1

    Topics: Anti-Infective Agents; Bacteremia; Ciprofloxacin; Drug and Narcotic Control; Drug Prescriptions; Dru

2001
Editorial comments on 'Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study'.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemot

2001
Assessment and treatment of low-risk febrile neutropenic (LRFN) pediatric patients with cancer.
    Medical and pediatric oncology, 2002, Volume: 38, Issue:4

    Topics: Anti-Infective Agents; Ceftriaxone; Cephalosporins; Child; Ciprofloxacin; Fever; Humans; Neoplasms;

2002
Reply to the article "Editorial comments on 'reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study'", by P.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:3

    Topics: Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cipro

2002
A pilot study of piperacillin and ciprofloxacin as initial therapy for fever in severely neutropenic leukemia patients.
    Scandinavian journal of infectious diseases, 1992, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Ciprofloxacin; Drug Therapy, Combination; Dru

1992
Occurrence of bacteremia in hematologic patients.
    European journal of epidemiology, 1992, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Aged; Bacteremia; Bone Marrow Transplantation; Catheterization; Ciprofloxacin; Fe

1992
Prevention of infection during neutropenia.
    British journal of haematology, 1992, Volume: 81, Issue:2

    Topics: Ciprofloxacin; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Fluconazole; Huma

1992
Optimal sampling theory and population modelling: application to determination of the influence of the microgravity environment on drug distribution and elimination.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:10

    Topics: Bayes Theorem; Ceftazidime; Chromatography, High Pressure Liquid; Ciprofloxacin; Cystic Fibrosis; Fe

1991
An assessment of the efficacy of antimicrobial prophylaxis in bone marrow autografts.
    Bone marrow transplantation, 1991, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Amphotericin B; Bacteremia; Bacterial Infections; Bone Marrow Transplantation; Ci

1991
Therapy of established experimental Pseudomonas aeruginosa infections with oral ciprofloxacin and five human monoclonal antibodies against lipopolysaccharide antigens.
    Antibiotics and chemotherapy, 1991, Volume: 44

    Topics: Animals; Antibodies, Monoclonal; Antigens, Bacterial; Burns; Cellulitis; Ciprofloxacin; Immunotherap

1991
[Neutropenia caused by ciprofloxacin and Escherichia coli bacteremia. Bone marrow examination].
    Medicina clinica, 1991, Sep-07, Volume: 97, Issue:7

    Topics: Bacteremia; Bone Marrow Examination; Ciprofloxacin; Escherichia coli Infections; Humans; Neutropenia

1991
[Ciprofloxacin-induced neutropenia: an infrequent adverse effect].
    Medicina clinica, 1991, Mar-02, Volume: 96, Issue:8

    Topics: Aged; Ciprofloxacin; Humans; Male; Neutropenia; Spondylitis

1991
In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin.
    Chemotherapy, 1990, Volume: 36, Issue:2

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Cefotaxime; Ciprofloxacin; Drug Evaluation, Pr

1990
Efficacy of a monoclonal antibody directed against tumor necrosis factor in protecting neutropenic rats from lethal infection with Pseudomonas aeruginosa.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:6

    Topics: Agranulocytosis; Animals; Antibodies, Monoclonal; Ciprofloxacin; Combined Modality Therapy; Disease

1990
Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:1

    Topics: Aged; Ciprofloxacin; Coagulase; Drug Resistance, Microbial; Female; Humans; Immune Tolerance; Leukem

1990
Outbreak of coagulase negative staphylococcus highly resistant to ciprofloxacin in a leukaemia unit.
    BMJ (Clinical research ed.), 1989, Jul-29, Volume: 299, Issue:6694

    Topics: Cancer Care Facilities; Ciprofloxacin; Coagulase; Cross Infection; Disease Outbreaks; Drug Resistanc

1989
In vivo activity of ciprofloxacin, ofloxacin, norfloxacin and pipemidic acid against Escherichia coli infections in mice.
    Drugs under experimental and clinical research, 1989, Volume: 15, Issue:2

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Mice; Microbial

1989
Multiply resistant Salmonella typhimurium septicaemia in an immunocompromised patient successfully treated with ciprofloxacin.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Drug Resistance, Microbial; Hu

1985
Synergy of ciprofloxacin and azlocillin in vitro and in a neutropenic mouse model of infection.
    European journal of clinical microbiology, 1986, Volume: 5, Issue:1

    Topics: Animals; Azlocillin; Bacteria; Carbenicillin; Ciprofloxacin; Drug Synergism; Drug Therapy, Combinati

1986
Two neutropenic patients with multiple resistant Pseudomonas aeruginosa septicaemia treated with ciprofloxacin.
    Journal of the Royal Society of Medicine, 1987, Volume: 80, Issue:5

    Topics: Adolescent; Aged; Agranulocytosis; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial;

1987
In vivo and in vitro activity of ciprofloxacin plus azlocillin against 12 streptococcal isolates in a neutropenic site model.
    Diagnostic microbiology and infectious disease, 1987, Volume: 7, Issue:2

    Topics: Amikacin; Animals; Azlocillin; Ciprofloxacin; Disease Models, Animal; Drug Synergism; Drug Therapy,

1987
Activity of ciprofloxacin and colistin against Pseudomonas aeruginosa isolates from neutropenic patients: a possible approach to prophylaxis.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:6

    Topics: Agranulocytosis; Ciprofloxacin; Colistin; Drug Resistance, Microbial; Humans; Microbial Sensitivity

1988
Activities of pefloxacin and ciprofloxacin in experimentally induced Pseudomonas pneumonia in neutropenic guinea pigs.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:4

    Topics: Agranulocytosis; Animals; Anti-Bacterial Agents; Ciprofloxacin; Guinea Pigs; Half-Life; Microbial Se

1985
Comparative efficacy of ciprofloxacin, ceftazidime and gentamicin, given alone or in combination, in a model of experimental septicemia due to Klebsiella pneumoniae in neutropenic mice.
    Infection, 1988, Volume: 16, Issue:1

    Topics: Agranulocytosis; Animals; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combinat

1988
A clinical, microbiological and pharmacokinetic study of ciprofloxacin plus vancomycin as initial therapy of febrile episodes in neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Ciprofloxacin; Drug Therapy, Combination; Fever; Humans; L

1988
Preliminary evaluation of ciprofloxacin, a new 4-quinolone antibiotic, in the treatment of febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl D

    Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Ciprofloxacin; Female; Fever; Half-Life; Humans;

1986
Therapeutic efficacy of cefpiramide-ciprofloxacin combination in experimental Pseudomonas infections in neutropenic mice.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:4

    Topics: Agranulocytosis; Animals; Cephalosporins; Ciprofloxacin; Cyclophosphamide; Drug Therapy, Combination

1987