ciprofloxacin has been researched along with Middle Ear Inflammation in 57 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Randomized, patient-masked, parallel-group, multicenter trial of topical otic ciprofloxacin/dexamethasone versus topical ciprofloxacin alone in 201 children aged 6 months to 12 years with acute otitis media with tympanostomy tubes (AOMT) of less than or equal to 3 weeks' duration and visible otorrhea." | 9.10 | Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes. ( Anon, JB; Conroy, PJ; Dupre, SJ; Hogg, G; Krueger, KA; Moe, RD; Potts, S; Roland, PS; Stroman, DW; Wall, GM, 2003) |
| "A multicentre double-blind randomized study was carried out to compare topical ciprofloxacin and topical gentamicin in the treatment of simple non-cholesteatomatous purulent chronic otitis media." | 9.08 | [Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase]. ( Abelló, P; Dicenta, M; Jiménez, R; Lorente, J; Maristany, M; Menem, J; Quesada, P; Sabater, F; Traserra, J; Viñas, J, 1995) |
| "To evaluate the efficacy of ciprofloxacin compared with tobramycin and placebo ear drops in the treatment of chronic suppurative otitis media without cholesteatoma." | 9.08 | Chronic otitis media treated topically with ciprofloxacin or tobramycin. ( Ben-David, J; Brodsky, A; Fradis, M; Larboni, J; Podoshin, L; Srugo, I, 1997) |
| "Clinical and bacteriological efficacy of topical ciprofloxacin hydrochloride was compared with that of intramuscular gentamicin sulfate in two groups composed of 30 patients each, all of whom were affected by chronic otitis media in the acute stage." | 9.07 | Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. ( D'Errico, G; Esposito, S; Montanaro, C; Noviello, S, 1992) |
| "The clinical and bacteriological efficacy of ciprofloxacin was studied in three groups composed of 20 patients each, all of whom were affected by chronic otitis media in the acute stage." | 9.06 | Topical and oral treatment of chronic otitis media with ciprofloxacin. A preliminary study. ( D'Errico, G; Esposito, S; Montanaro, C, 1990) |
| "80 adult outpatients suffering from otitis media, sinusitis (maxillaris or frontalis) or peritonsillitis were treated with 500 mg ciprofloxacin b." | 9.06 | Antibacterial treatment of otitis and sinusitis with ciprofloxacin and penicillin V--a comparison. ( Falser, N; Mittermayer, H; Weuta, H, 1988) |
| "OTO-201 can provide sustained release to the middle ear and effectively treat otitis media, when compared with FDA-approved ciprofloxacin otic drop formulations." | 7.80 | OTO-201: nonclinical assessment of a sustained-release ciprofloxacin hydrogel for the treatment of otitis media. ( Altschuler, RA; Dellamary, L; Dolan, DF; Fernandez, R; Harrop-Jones, A; Hou, HJ; LeBel, C; Piu, F; Tsivkovskaia, N; Wang, X, 2014) |
| "7%) of the patients receiving fluocinolone presented with adverse events related to study medication." | 6.84 | Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial. ( Ansley, J; Butehorn, HF; Byers, J; Douglis, F; Esterhuizen, K; Hernández, FJ; Hussain, I; Ismail, K; Lanier, B; Lansford, B; Pumarola, F; Spektor, Z, 2017) |
| "Primary: to compare one-off administration of boric acid powder with courses of 1% acetic acid and ciprofloxacin eardrops in treating active chronic otitis media." | 5.16 | A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings. ( Loock, JW, 2012) |
| "Randomized, patient-masked, parallel-group, multicenter trial of topical otic ciprofloxacin/dexamethasone versus topical ciprofloxacin alone in 201 children aged 6 months to 12 years with acute otitis media with tympanostomy tubes (AOMT) of less than or equal to 3 weeks' duration and visible otorrhea." | 5.10 | Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes. ( Anon, JB; Conroy, PJ; Dupre, SJ; Hogg, G; Krueger, KA; Moe, RD; Potts, S; Roland, PS; Stroman, DW; Wall, GM, 2003) |
| "A multicentre double-blind randomized study was carried out to compare topical ciprofloxacin and topical gentamicin in the treatment of simple non-cholesteatomatous purulent chronic otitis media." | 5.08 | [Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase]. ( Abelló, P; Dicenta, M; Jiménez, R; Lorente, J; Maristany, M; Menem, J; Quesada, P; Sabater, F; Traserra, J; Viñas, J, 1995) |
| "To evaluate the efficacy of ciprofloxacin compared with tobramycin and placebo ear drops in the treatment of chronic suppurative otitis media without cholesteatoma." | 5.08 | Chronic otitis media treated topically with ciprofloxacin or tobramycin. ( Ben-David, J; Brodsky, A; Fradis, M; Larboni, J; Podoshin, L; Srugo, I, 1997) |
| "Clinical and bacteriological efficacy of topical ciprofloxacin hydrochloride was compared with that of intramuscular gentamicin sulfate in two groups composed of 30 patients each, all of whom were affected by chronic otitis media in the acute stage." | 5.07 | Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. ( D'Errico, G; Esposito, S; Montanaro, C; Noviello, S, 1992) |
| "The clinical and bacteriological efficacy of ciprofloxacin was studied in three groups composed of 20 patients each, all of whom were affected by chronic otitis media in the acute stage." | 5.06 | Topical and oral treatment of chronic otitis media with ciprofloxacin. A preliminary study. ( D'Errico, G; Esposito, S; Montanaro, C, 1990) |
| "80 adult outpatients suffering from otitis media, sinusitis (maxillaris or frontalis) or peritonsillitis were treated with 500 mg ciprofloxacin b." | 5.06 | Antibacterial treatment of otitis and sinusitis with ciprofloxacin and penicillin V--a comparison. ( Falser, N; Mittermayer, H; Weuta, H, 1988) |
| "A 58-year-old male developed fulminating musculoskeletal pain associated with third-time exposure to ciprofloxacin administered for treatment of chronic otitis media." | 4.85 | Ciprofloxacin-related acute severe myalgia necessitating emergency care treatment: a case report and review of the literature. ( Eisele, S; Garbe, E; Schneider, T; Somasundaram, R; Zeitz, M, 2009) |
| "OTO-201 can provide sustained release to the middle ear and effectively treat otitis media, when compared with FDA-approved ciprofloxacin otic drop formulations." | 3.80 | OTO-201: nonclinical assessment of a sustained-release ciprofloxacin hydrogel for the treatment of otitis media. ( Altschuler, RA; Dellamary, L; Dolan, DF; Fernandez, R; Harrop-Jones, A; Hou, HJ; LeBel, C; Piu, F; Tsivkovskaia, N; Wang, X, 2014) |
| "Enoxacin was effective in 35%; ciprofloxacin (five publications) was used in 82 patients with 67% effectivity in otitis externa and otitis media and 61% effectivity in radical mastoid cavity infection." | 3.76 | The use of fluoroquinolones in chronic otitis suppurativa. ( Claes, J; Pattyn, SR; Valcke, HD; van Caekenberghe, DL; van de Heyning, PH, 1987) |
| "The efficacy and safety of ciprofloxacin in the treatment of Pseudomonas aeruginosa infections was evaluated in 72 patients suffering from upper urinary tract infection (19 patients), deep soft tissue infection (16), chronic osteomyelitis (12), abscess (7), chronic otitis media (6), otitis externa (3) and bronchopneumonia (9)." | 3.67 | Evaluation of ciprofloxacin in the treatment of Pseudomonas aeruginosa infections. ( Daikos, GK; Daphnis, E; Dendrinos, C; Galanakis, N; Giamarellou, H; Stefanou, J, 1986) |
| "7%) of the patients receiving fluocinolone presented with adverse events related to study medication." | 2.84 | Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial. ( Ansley, J; Butehorn, HF; Byers, J; Douglis, F; Esterhuizen, K; Hernández, FJ; Hussain, I; Ismail, K; Lanier, B; Lansford, B; Pumarola, F; Spektor, Z, 2017) |
| "Topical ciprofloxacin is a safe and uncomplicated ototoxic drug that is an effective antibiotic used in the treatment of refractory chronic otitis those dregs such as pseudomonas aerogenusa and staphylococci resistant to methicillin are responsible for it, which in the usual doses has not harmful effects on hearing hairy cells." | 2.79 | Comparison of local and systemic ciprofloxacin ototoxicity in the treatment of chronic media otitis. ( Samarei, R, 2014) |
| "Ciprofloxacin/dexamethasone has been demonstrated as safe and effective with regard to clinical cures and microbiological eradication of pathogens in either disease with low treatment failure rates." | 2.45 | Ciprofloxacin 0.3%/dexamethasone 0.1% sterile otic suspension for the topical treatment of ear infections: a review of the literature. ( Dohar, J; Roland, PS; Stroman, DW; Wall, GM, 2009) |
| "Ciprofloxacin was effective against Staphylococcus aureus, but Pseudomonas aeruginosa strains were ciprofloxacin resistant." | 1.72 | Analysis of pathogens and antimicrobial treatment in different groups of patients with chronic otitis media. ( Budzyńska, A; Gospodarek-Komkowska, E; Janiak-Kiszka, J; Kaźmierczak, H; Kaźmierczak, W; Nowaczewska, M, 2022) |
| " While the use of topical drops can minimize the administered dose of antibiotic and adverse systemic effects compared to oral antibiotics, their use has limitations, partially due to low patient compliance, high dosing frequency, and difficulty of administration." | 1.56 | Controlled release of ciprofloxacin and ceftriaxone from a single ototopical administration of antibiotic-loaded polymer microspheres and thermoresponsive gel. ( Alper, CM; Bruk, LA; Dunkelberger, KE; Fedorchak, MV; Hong, W; Khampang, P; Sadagopan, S, 2020) |
| "Otitis media is the most common reason U." | 1.43 | Treatment of otitis media by transtympanic delivery of antibiotics. ( Guo, S; Kohane, DS; Lin, LY; Okonkwo, OS; Pelton, SI; Rosowski, JJ; Sabharwal, V; Shlykova, N; Tong, R; Wang, W; Yang, R, 2016) |
| "Ciprofloxacin was highly) effective antimicrobial agent in vitro against majority of the bacterial isolates." | 1.34 | Antimicrobial resistance patterns of clinical bacterial isolates in southwestern Ethiopia. ( Gebre-Sealsssie, S, 2007) |
| "Ciprofloxacin resistance has increased, while Ceftazidime susceptibility is unchanged (> 90 %)." | 1.31 | [Current therapeutical management, new antibiotics and treatment of Pseudomonas aeruginosa in bacterial ENT-infections]. ( Elies, W, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (17.54) | 18.7374 |
| 1990's | 13 (22.81) | 18.2507 |
| 2000's | 17 (29.82) | 29.6817 |
| 2010's | 13 (22.81) | 24.3611 |
| 2020's | 4 (7.02) | 2.80 |
| Authors | Studies |
|---|---|
| Kaźmierczak, W | 1 |
| Janiak-Kiszka, J | 1 |
| Budzyńska, A | 1 |
| Nowaczewska, M | 1 |
| Kaźmierczak, H | 1 |
| Gospodarek-Komkowska, E | 1 |
| Wang, LC | 1 |
| Phyland, DJ | 1 |
| Giddings, CE | 1 |
| Ku, M | 1 |
| Cheung, S | 1 |
| Slattery, W | 1 |
| Pierstorff, E | 1 |
| Bruk, LA | 1 |
| Dunkelberger, KE | 1 |
| Khampang, P | 1 |
| Hong, W | 1 |
| Sadagopan, S | 1 |
| Alper, CM | 1 |
| Fedorchak, MV | 1 |
| Alvi, SA | 1 |
| Jones, JW | 1 |
| Porter, P | 1 |
| Perryman, M | 1 |
| Nelson, K | 1 |
| Francis, CL | 1 |
| Larsen, CG | 1 |
| Yang, R | 2 |
| Sabharwal, V | 3 |
| Shlykova, N | 2 |
| Okonkwo, OS | 2 |
| Pelton, SI | 3 |
| Kohane, DS | 3 |
| Kutz, JW | 1 |
| Roland, PS | 4 |
| Lee, KH | 1 |
| Wang, X | 1 |
| Fernandez, R | 1 |
| Tsivkovskaia, N | 1 |
| Harrop-Jones, A | 1 |
| Hou, HJ | 1 |
| Dellamary, L | 1 |
| Dolan, DF | 1 |
| Altschuler, RA | 1 |
| LeBel, C | 1 |
| Piu, F | 1 |
| Samarei, R | 1 |
| Park, MH | 1 |
| Kim, SY | 1 |
| Roh, EY | 1 |
| Lee, HS | 1 |
| Tong, R | 1 |
| Lin, LY | 1 |
| Wang, W | 1 |
| Guo, S | 1 |
| Rosowski, JJ | 2 |
| Spektor, Z | 1 |
| Pumarola, F | 1 |
| Ismail, K | 1 |
| Lanier, B | 1 |
| Hussain, I | 1 |
| Ansley, J | 1 |
| Butehorn, HF | 1 |
| Esterhuizen, K | 1 |
| Byers, J | 1 |
| Douglis, F | 1 |
| Lansford, B | 1 |
| Hernández, FJ | 1 |
| Wall, GM | 2 |
| Stroman, DW | 2 |
| Dohar, J | 1 |
| Eisele, S | 1 |
| Garbe, E | 1 |
| Zeitz, M | 1 |
| Schneider, T | 1 |
| Somasundaram, R | 1 |
| Kavanagh, KR | 1 |
| Parham, K | 1 |
| Schoem, SR | 1 |
| Antonelli, PJ | 2 |
| Winterstein, AG | 1 |
| Schultz, GS | 1 |
| Loock, JW | 1 |
| Jang, CH | 2 |
| Cho, YB | 1 |
| Choi, CH | 1 |
| Lee, JS | 1 |
| Kang, SI | 1 |
| Khoo, X | 1 |
| Simons, EJ | 1 |
| Chiang, HH | 1 |
| Hickey, JM | 1 |
| Langer, R | 1 |
| Park, SY | 1 |
| Orr, CF | 1 |
| Rowe, DB | 1 |
| Anon, JB | 1 |
| Moe, RD | 1 |
| Conroy, PJ | 1 |
| Dupre, SJ | 1 |
| Krueger, KA | 1 |
| Potts, S | 1 |
| Hogg, G | 1 |
| Pontius, A | 1 |
| Michael Wall, G | 1 |
| Waycaster, CR | 1 |
| Olivera, ME | 1 |
| Bistoni, A | 1 |
| Anun, HE | 1 |
| Salinas, A | 1 |
| Manzo, RH | 1 |
| Becvarovski, Z | 1 |
| Kumar, VV | 1 |
| Gaughan, J | 1 |
| Isaacson, G | 1 |
| Szeremeta, W | 1 |
| Kaplan, DM | 1 |
| James, AL | 1 |
| Thorp, MA | 1 |
| Mount, RJ | 1 |
| Harrison, RV | 1 |
| Killingley, B | 1 |
| Carpenter, V | 1 |
| Flanagan, K | 1 |
| Pasvol, G | 1 |
| Shefelbine, SE | 1 |
| Young, LJ | 1 |
| Gebre-Sealsssie, S | 1 |
| Lorente, J | 1 |
| Sabater, F | 1 |
| Maristany, M | 1 |
| Jiménez, R | 1 |
| Menem, J | 1 |
| Viñas, J | 1 |
| Quesada, P | 1 |
| Traserra, J | 1 |
| Dicenta, M | 1 |
| Abelló, P | 1 |
| Tutkun, A | 1 |
| García Rodríguez, JA | 1 |
| García Sánchez, JE | 1 |
| García García, MI | 1 |
| García Sánchez, E | 1 |
| Muñoz Bellido, JL | 1 |
| Ramos Macías, A | 1 |
| Gaillot, O | 1 |
| Berche, P | 1 |
| Kasemsuwan, L | 1 |
| Clongsuesuek, P | 1 |
| Fradis, M | 1 |
| Brodsky, A | 1 |
| Ben-David, J | 1 |
| Srugo, I | 1 |
| Larboni, J | 1 |
| Podoshin, L | 1 |
| Joseph, EM | 1 |
| Sperling, NM | 1 |
| Fontanel, JP | 1 |
| Petersen, W | 1 |
| Laprell, H | 1 |
| Kuczkowski, J | 1 |
| Samet, A | 1 |
| Brzoznowski, W | 1 |
| Lelièvre, G | 1 |
| Elies, W | 1 |
| Marone, C | 1 |
| Quadri, F | 1 |
| Esposito, S | 2 |
| Noviello, S | 1 |
| D'Errico, G | 2 |
| Montanaro, C | 2 |
| Karp, P | 1 |
| Wyss, E | 1 |
| Alame, S | 1 |
| Mons, P | 1 |
| Kebbi, H | 1 |
| Decaux, F | 1 |
| Peters, B | 1 |
| Pinching, AJ | 1 |
| Stange, G | 1 |
| Ganz, H | 2 |
| Van de Heyning, PH | 2 |
| Pattyn, SR | 2 |
| Valcke, HD | 2 |
| Giamarellou, H | 2 |
| Daphnis, E | 2 |
| Dendrinos, C | 2 |
| Daikos, GK | 2 |
| Galanakis, N | 1 |
| Stefanou, J | 1 |
| Falser, N | 1 |
| Mittermayer, H | 1 |
| Weuta, H | 1 |
| van Caekenberghe, DL | 1 |
| Claes, J | 1 |
| Dibb, WL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Double-Blind Clinical Trial to Assess the Efficacy and Safety of DF289 Plus DF277 Otic Solution Compared to DF289 Otic Solution and to DF277 Otic Solution in the Treatment of Acute Otitis Media With Tympanostomy Tubes (AOMT) in [NCT01404611] | Phase 3 | 331 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| Clinical Study to Assess the Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Middle Ear Infections in Pediatric Patients[NCT01395966] | Phase 3 | 331 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| N-Acetylcysteine as an Adjunct for Refractory Chronic Suppurative Otitis Media[NCT00956748] | Phase 4 | 0 participants (Actual) | Interventional | 2019-11-29 | Withdrawn (stopped due to Lack of staff, time, and resources) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01404611)
Timeframe: From baseline until the end of the study (up to 22 days)
| Intervention | days (Median) |
|---|---|
| DF289 | 6.83 |
| DF277 | 22 |
| DF289 Plus DF277 | 4.94 |
(NCT01395966)
Timeframe: From baseline until the end of the study ( up to 22 days)
| Intervention | days (Median) |
|---|---|
| DF289 | 7.69 |
| DF277 | 22 |
| DF289 Plus DF277 | 3.75 |
6 reviews available for ciprofloxacin and Middle Ear Inflammation
| Article | Year |
|---|---|
Ciprofloxacin 0.3% + dexamethasone 0.1% for the treatment for otitis media.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Dexamethasone; Drug Combinations; Glucocorticoids; Hu | 2013 |
Ciprofloxacin/fluocinolone (Otovel) for otitis media with tympanostomy tubes.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Fluocinolone Aceto | 2016 |
Ciprofloxacin 0.3%/dexamethasone 0.1% sterile otic suspension for the topical treatment of ear infections: a review of the literature.
Topics: Administration, Topical; Anti-Infective Agents; Anti-Inflammatory Agents; Ciprofloxacin; Dexamethaso | 2009 |
Ciprofloxacin-related acute severe myalgia necessitating emergency care treatment: a case report and review of the literature.
Topics: Acute Disease; Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Emergencies; Humans; Injection | 2009 |
Absorption of intratympanic topical antibiotics.
Topics: Absorption; Administration, Topical; Animals; Anti-Infective Agents, Local; Ciprofloxacin; Humans; O | 2004 |
The use of fluoroquinolones in chronic otitis suppurativa.
Topics: Cholesteatoma; Chronic Disease; Ciprofloxacin; Clinical Trials as Topic; Enoxacin; Humans; Mastoidit | 1987 |
15 trials available for ciprofloxacin and Middle Ear Inflammation
| Article | Year |
|---|---|
A randomised clinical trial of single or extended dosing ciprofloxacin versus no intervention for prevention of ventilation tube otorrhoea and obstruction (PreVenTO2).
Topics: Anti-Bacterial Agents; Child, Preschool; Ciprofloxacin; Female; Humans; Infant; Male; Middle Ear Ven | 2022 |
Steroid Versus Antibiotic Drops in the Prevention of Postoperative Myringotomy Tube Complications.
Topics: Administration, Topical; Anti-Bacterial Agents; Ciprofloxacin; Dexamethasone; Female; Follow-Up Stud | 2018 |
Comparison of local and systemic ciprofloxacin ototoxicity in the treatment of chronic media otitis.
Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Audiometry; Chronic Disease; C | 2014 |
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial.
Topics: Acute Disease; Administration, Topical; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxaci | 2017 |
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial.
Topics: Acute Disease; Administration, Topical; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxaci | 2017 |
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial.
Topics: Acute Disease; Administration, Topical; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxaci | 2017 |
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial.
Topics: Acute Disease; Administration, Topical; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxaci | 2017 |
A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings.
Topics: Acetic Acid; Administration, Topical; Adult; Analysis of Variance; Anti-Infective Agents; Audiometry | 2012 |
Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes.
Topics: Acute Disease; Administration, Topical; Cerebrospinal Fluid Otorrhea; Child; Child, Preschool; Cipro | 2003 |
Ototopical ciprofloxacin in a glycerin vehicle for the treatment of acute external otitis.
Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective A | 2004 |
[Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase].
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Aspergillus; Candida albica | 1995 |
Efficacy of topical ciprofloxacin in the treatment of ear infections in adults.
Topics: Administration, Topical; Adult; Bacterial Infections; Chronic Disease; Ciprofloxacin; Ear Diseases; | 1993 |
A double blind, prospective trial of topical ciprofloxacin versus normal saline solution in the treatment of otorrhoea.
Topics: Administration, Topical; Adult; Aged; Anti-Infective Agents; Bacteria, Aerobic; Cerebrospinal Fluid | 1997 |
Chronic otitis media treated topically with ciprofloxacin or tobramycin.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; | 1997 |
Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media.
Topics: Administration, Topical; Adult; Chronic Disease; Ciprofloxacin; Female; Gentamicins; Humans; Injecti | 1992 |
Topical and oral treatment of chronic otitis media with ciprofloxacin. A preliminary study.
Topics: Administration, Oral; Administration, Topical; Adult; Chronic Disease; Ciprofloxacin; Drug Administr | 1990 |
Antibacterial treatment of otitis and sinusitis with ciprofloxacin and penicillin V--a comparison.
Topics: Adult; Bacterial Infections; Ciprofloxacin; Clinical Trials as Topic; Frontal Sinus; Humans; Maxilla | 1988 |
The use of fluoroquinolones in chronic otitis suppurativa.
Topics: Cholesteatoma; Chronic Disease; Ciprofloxacin; Clinical Trials as Topic; Enoxacin; Humans; Mastoidit | 1987 |
37 other studies available for ciprofloxacin and Middle Ear Inflammation
| Article | Year |
|---|---|
Analysis of pathogens and antimicrobial treatment in different groups of patients with chronic otitis media.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Escherichia coli; Fe | 2022 |
An extended release ciprofloxacin/dexamethasone hydrogel for otitis media.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Ciprofloxacin; Dexamethasone; Guinea Pigs; | 2020 |
Controlled release of ciprofloxacin and ceftriaxone from a single ototopical administration of antibiotic-loaded polymer microspheres and thermoresponsive gel.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Bacterial Agents; Ceftriaxone; Chinchilla; Cip | 2020 |
Treatment of Streptococcus pneumoniae otitis media in a chinchilla model by transtympanic delivery of antibiotics.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Ciprofloxacin; Disease Models, Animal; Dose-Response Rel | 2018 |
OTO-201: nonclinical assessment of a sustained-release ciprofloxacin hydrogel for the treatment of otitis media.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Chinchilla; Ciprofloxacin; Delayed-Action P | 2014 |
Difference of Type 3 secretion system (T3SS) effector gene genotypes (exoU and exoS) and its implication to antibiotics resistances in isolates of Pseudomonas aeruginosa from chronic otitis media.
Topics: ADP Ribose Transferases; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; | 2017 |
Treatment of otitis media by transtympanic delivery of antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Biomechanical Phenomena; Child; Chinchilla; | 2016 |
Auditory function after a prolonged course of ciprofloxacin-dexamethasone otic suspension in a murine model.
Topics: Acute Disease; Animals; Anti-Infective Agents; Ciprofloxacin; Dexamethasone; Disease Models, Animal; | 2009 |
Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study.
Topics: Administration, Cutaneous; Animals; Anti-Infective Agents; Chi-Square Distribution; Chinchilla; Cipr | 2010 |
Effect of anti-adhesion barrier solution containing ciprofloxacin-hydrocortisone on abraded mucosa with otitis media.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Ciprofloxacin; Disease Models, Animal; Drug | 2013 |
Formulations for trans-tympanic antibiotic delivery.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Ciprofloxacin; Drug Compounding; Male; Nanocapsules; Oti | 2013 |
Emergence of ciprofloxacin-resistant pseudomonas in pediatric otitis media.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Ciprofl | 2003 |
Eardrop attacks: seizures triggered by ciprofloxacin eardrops.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Combinations; Drug Therapy, Combination; Female; Hu | 2003 |
A cost threshold analysis of ciprofloxacin-dexamethasone versus ofloxacin for acute otitis media in pediatric patients with tympanostomy tubes.
Topics: Anti-Bacterial Agents; Canada; Child; Ciprofloxacin; Cost-Benefit Analysis; Costs and Cost Analysis; | 2004 |
Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction.
Topics: Administration, Topical; Adolescent; Adrenergic alpha-Agonists; Anti-Infective Agents; Antibiotic Pr | 2005 |
Effects of middle ear application of Cipro HC Otic Suspension in an animal model.
Topics: Animals; Anti-Infective Agents; Auditory Perception; Chinchilla; Ciprofloxacin; Cochlea; Evoked Pote | 2004 |
Pneumococcal meningitis and etanercept--chance or association?
Topics: Antirheumatic Agents; Ceftriaxone; Ciprofloxacin; Disease Susceptibility; Etanercept; Female; Humans | 2005 |
Mitigation of hearing loss from semi-circular canal transection in pseudomonas otitis media with ciprofloxacin-dexamethasone irrigation.
Topics: Animals; Anti-Infective Agents; Auditory Threshold; Ciprofloxacin; Dexamethasone; Glucocorticoids; G | 2006 |
Antimicrobial resistance patterns of clinical bacterial isolates in southwestern Ethiopia.
Topics: Anti-Infective Agents; Child; Ciprofloxacin; Cross-Sectional Studies; Drug Resistance, Multiple, Bac | 2007 |
Ciprofloxacin.
Topics: Administration, Topical; Ciprofloxacin; Humans; Otitis Media | 1994 |
In vitro susceptibility to ciprofloxacin of bacterial strains isolated from chronic otitis media and chronic sinusitis.
Topics: Adult; Anti-Infective Agents; Bacteria; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; | 1995 |
Facial nerve paralysis in acute otitis media: cause and management revisited.
Topics: Acute Disease; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Age | 1998 |
[Role of ciprofloxacin in the treatment of chronic otitis media].
Topics: Administration, Oral; Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; A | 1998 |
[Insidious rupture of the Achilles tendon after ciprofloxacin-induced tendopathy. A case report].
Topics: Achilles Tendon; Adult; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Necrosis; Otitis Media | 1998 |
[Bacteriologic evaluation of otitis externa and chronic otitis media].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Aspergillus; Bacteria; Candida; Child; Chronic | 2000 |
[Chronic ORL infections of the adult in the community. Role of ciprofloxacin].
Topics: Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; Humans; Otitis Media; S | 2001 |
[Current therapeutical management, new antibiotics and treatment of Pseudomonas aeruginosa in bacterial ENT-infections].
Topics: Ceftazidime; Chronic Disease; Ciprofloxacin; Clinical Trials as Topic; Dose-Response Relationship, D | 2002 |
Beware of ciprofloxacin in acute otitis media.
Topics: Acute Disease; Ciprofloxacin; Drug Resistance, Microbial; Humans; Male; Meningitis, Pneumococcal; Mi | 1992 |
[Pneumococcal meningitis during ciprofloxacin therapy for otitis media].
Topics: Adult; Ciprofloxacin; Humans; Male; Meningitis, Pneumococcal; Otitis Media | 1991 |
Fatal anaphylaxis associated with ciprofloxacin in a patient with AIDS related complex.
Topics: Administration, Oral; Adult; AIDS-Related Complex; Anaphylaxis; Ciprofloxacin; Humans; Male; Otitis | 1989 |
[Local treatment of Pseudomonas infection of the ear. A small clinical study].
Topics: Audiometry, Pure-Tone; Auditory Threshold; Ciprofloxacin; Follow-Up Studies; Humans; Otitis Externa; | 1989 |
[Local antibiotic therapy of bacterial ear infections].
Topics: Administration, Topical; Bacterial Infections; Ciprofloxacin; Humans; Lymphadenitis; Mastoiditis; Ot | 1989 |
Ciprofloxacin in oral treatment of ear infections.
Topics: Administration, Oral; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Humans; Male; O | 1986 |
Experience with ciprofloxacin in the treatment of various infections caused mainly by Pseudomonas aeruginosa.
Topics: Abscess; Administration, Oral; Adolescent; Adult; Aged; Bronchopneumonia; Child; Ciprofloxacin; Fema | 1985 |
Evaluation of ciprofloxacin in the treatment of Pseudomonas aeruginosa infections.
Topics: Abscess; Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bronchopneumonia; Chi | 1986 |
[Gyrase inhibitor in the local treatment of the chronically infected middle ear following surgery].
Topics: Administration, Topical; Adult; Aged; Bacterial Infections; Ciprofloxacin; Drug Resistance; Escheric | 1986 |
External otitis in divers: etiology and in vitro activity of ciprofloxacin and local agents.
Topics: Acinetobacter; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Diving; Enterobacteriacea | 1987 |