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ciprofloxacin and Malaria

ciprofloxacin has been researched along with Malaria in 12 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"A randomized, open study of high-dose ciprofloxacin (750 mg every 12 h) in uncomplicated falciparum malaria was conducted in Thailand."9.07Ciprofloxacin treatment of drug-resistant falciparum malaria. ( Edstein, MD; Pavanand, K; Shanks, GD; Watt, G; Webster, HK; Wechgritaya, S, 1991)
"We investigated the in vivo antimalarial activities of pefloxacin and ciprofloxacin in Swiss albino mice infected intravenously with 5 x 10(6) Plasmodium yoelii N67 parasites 1 h before treatment."7.68Activities of pefloxacin and ciprofloxacin against experimental malaria in mice. ( Deloron, P; Gaudin, C; Lebras, J; Malhotra, K; Pocidalo, JJ; Salmon, D, 1990)
"A randomized, open study of high-dose ciprofloxacin (750 mg every 12 h) in uncomplicated falciparum malaria was conducted in Thailand."5.07Ciprofloxacin treatment of drug-resistant falciparum malaria. ( Edstein, MD; Pavanand, K; Shanks, GD; Watt, G; Webster, HK; Wechgritaya, S, 1991)
"The increasing spread of chloroquine resistant malaria has intensified the search for new antimalarial treatment, especially drugs that can be used in combination."3.78Interaction between ciprofloxacin and chloroquine in mice infected with chloroquine resistant Plasmodium berghei: interaction between ciprofloxacin and chloroqune. ( Abiodun, OO; Gbotosho, GO; Happi, CT; Oduola, AM; Sowunmi, A; Woranola, O, 2012)
"The antimalarial activity of combinations of mefloquine or artesunic acid with ciprofloxacin and other synthetic fluoroquinolone was tested in vitro against Plasmodium falciparum using a strain (BHz26/86) partially resistant to chloroquine and a resistant clone (W2); both are sensitive to mefloquine."3.74Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin. ( Andrade, AA; Boechat, N; de Freitas, IO; de Pilla Varotti, F; de Souza, MV; Krettli, AU; Vasconcelos, TR, 2007)
"We investigated the in vivo antimalarial activities of pefloxacin and ciprofloxacin in Swiss albino mice infected intravenously with 5 x 10(6) Plasmodium yoelii N67 parasites 1 h before treatment."3.68Activities of pefloxacin and ciprofloxacin against experimental malaria in mice. ( Deloron, P; Gaudin, C; Lebras, J; Malhotra, K; Pocidalo, JJ; Salmon, D, 1990)
"Typhoid fever is an acute infectious disease caused by Salmonella serotype Typhi, leading to endemic or epidemic outbreaks in tropical/ subtropical countries (especially in India, Southeast Asia, Central and South Africa)."1.33[A case with fever of unknown origin during treatment for malaria: multi-drug resistant Salmonella typhi infection]. ( Akin, K; Cesur, S; Esen, B; Levent, B; Willke, A; Yavuzdemir, S, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's4 (33.33)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amorha, KC1
Ugwuowo, OB1
Ayogu, EE1
Nduka, SO1
Okonta, MJ1
Levine, AC1
Shetty, PP1
Henwood, PC1
Sabeti, P1
Katz, JT1
Vaidya, A1
Falajiki, YF1
Akinola, O1
Abiodun, OO2
Happi, CT2
Sowunmi, A2
Gbotosho, GO2
Woranola, O1
Oduola, AM1
Akin, K1
Yavuzdemir, S1
Cesur, S1
Levent, B1
Esen, B1
Willke, A1
Andrade, AA1
de Pilla Varotti, F1
de Freitas, IO1
de Souza, MV1
Vasconcelos, TR1
Boechat, N1
Krettli, AU1
López-Vélez, R1
Sánchez Mancilla, R1
García Camacho, A1
Salmon, D1
Deloron, P1
Gaudin, C1
Malhotra, K1
Lebras, J1
Pocidalo, JJ1
Watt, G1
Shanks, GD1
Edstein, MD1
Pavanand, K1
Webster, HK1
Wechgritaya, S1
Krishna, S1
Davis, TM1
Chan, PC1
Wells, RA1
Robson, KJ1

Trials

1 trial available for ciprofloxacin and Malaria

ArticleYear
Ciprofloxacin treatment of drug-resistant falciparum malaria.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:3

    Topics: Adult; Animals; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria; M

1991

Other Studies

11 other studies available for ciprofloxacin and Malaria

ArticleYear
Evaluation of the hepatic effect of concomitant administration of ciprofloxacin and some antimalarial drugs in Plasmodium berghei infected mice: An in vivo study.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Chemical and Drug Induced Liver Injury; Ciprofloxacin

2018
Interactive medical case. A Liberian health care worker with fever.
    The New England journal of medicine, 2015, Jan-29, Volume: 372, Issue:5

    Topics: Anti-Bacterial Agents; Antibodies, Viral; Ciprofloxacin; Combined Modality Therapy; Diagnosis, Diffe

2015
Amodiaquine-Ciprofloxacin: a potential combination therapy against drug resistant malaria.
    Parasitology, 2015, Volume: 142, Issue:6

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Ciprofloxacin; Dose-Response Relationship, Drug; D

2015
Interaction between ciprofloxacin and chloroquine in mice infected with chloroquine resistant Plasmodium berghei: interaction between ciprofloxacin and chloroqune.
    Parasitology research, 2012, Volume: 110, Issue:2

    Topics: Animals; Antimalarials; Chloroquine; Ciprofloxacin; Disease Models, Animal; Drug Resistance; Drug Th

2012
[A case with fever of unknown origin during treatment for malaria: multi-drug resistant Salmonella typhi infection].
    Mikrobiyoloji bulteni, 2005, Volume: 39, Issue:1

    Topics: Adult; Afghanistan; Agglutination Tests; Anti-Infective Agents; Antibodies, Bacterial; Ciprofloxacin

2005
Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin.
    European journal of pharmacology, 2007, Mar-08, Volume: 558, Issue:1-3

    Topics: Animals; Antimalarials; Artemisinins; Ciprofloxacin; Drug Synergism; Malaria; Mefloquine; Mice; Para

2007
Fluoroquinolone antimicrobials.
    Tropical and geographical medicine, 1995, Volume: 47, Issue:4

    Topics: Adult; Animals; Anti-Infective Agents; Antimalarials; Ciprofloxacin; Democratic Republic of the Cong

1995
Advice for travelers.
    The Medical letter on drugs and therapeutics, 1998, Apr-24, Volume: 40, Issue:1025

    Topics: Anti-Infective Agents; Antidiarrheals; Bacterial Vaccines; Cholera; Ciprofloxacin; Diarrhea; Diphthe

1998
Advice for travelers.
    The Medical letter on drugs and therapeutics, 2002, Apr-15, Volume: 44, Issue:1128

    Topics: Africa; Altitude Sickness; Asia; Chloroquine; Ciprofloxacin; Contraindications; Diarrhea; Female; He

2002
Activities of pefloxacin and ciprofloxacin against experimental malaria in mice.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:12

    Topics: Animals; Ciprofloxacin; Female; Malaria; Mice; Pefloxacin; Plasmodium yoelii; Staining and Labeling

1990
Ciprofloxacin and malaria.
    Lancet (London, England), 1988, May-28, Volume: 1, Issue:8596

    Topics: Animals; Ciprofloxacin; Humans; Malaria; Plasmodium falciparum; Time Factors

1988