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ciprofloxacin and Magnesium Deficiency

ciprofloxacin has been researched along with Magnesium Deficiency in 4 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)

Research Excerpts

ExcerptRelevanceReference
"5 and 6 h after dosing and the drug was still detectable in plasma 48 h after dosing (0."1.30Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics. ( Förster, C; Günther, T; Lozo, E; Merker, HJ; Schwabe, R; Stahlmann, R; Vormann, J; Zippel, U, 1997)
" In addition, the formation of metal chelates is also believed to be the reason for the significant reduction in oral bioavailability for the quinolones when concomitantly dosed with oral cation containing agents."1.30Effects of order of magnesium exposure on the postantibiotic effect and bactericidal activity of ciprofloxacin. ( Lam, JS; Lau, PY; Li, RC; Lo, KN, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Förster, C2
Schwabe, R1
Lozo, E1
Zippel, U1
Vormann, J2
Günther, T1
Merker, HJ1
Stahlmann, R3
Rücker, M1
Shakibaei, M2
Baumann-Wilschke, I1
Li, RC1
Lo, KN1
Lam, JS1
Lau, PY1
de Souza, P1
van Sickle, D1

Other Studies

4 other studies available for ciprofloxacin and Magnesium Deficiency

ArticleYear
Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics.
    Archives of toxicology, 1997, Volume: 72, Issue:1

    Topics: Age Factors; Animals; Anti-Infective Agents; Calcium; Cartilage; Ciprofloxacin; Contraindications; F

1997
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
    Archives of toxicology, 1998, Volume: 72, Issue:7

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian;

1998
Effects of order of magnesium exposure on the postantibiotic effect and bactericidal activity of ciprofloxacin.
    Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:4

    Topics: Anti-Infective Agents; Chelating Agents; Ciprofloxacin; Dietary Supplements; Dose-Response Relations

1999
Biochemical changes in Achilles tendon from juvenile dogs after treatment with ciprofloxacin or feeding a magnesium-deficient diet.
    Archives of toxicology, 2001, Volume: 75, Issue:6

    Topics: Achilles Tendon; Administration, Oral; Animal Feed; Animals; Anti-Infective Agents; Blotting, Wester

2001