ciprofloxacin has been researched along with Leukopenia in 12 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective randomized trial, 40 stage IV breast cancer patients undergoing intermediate high-dose chemotherapy (cyclophosphamide, 5-fluorouracil plus epirubicin or methotrexate), received either recombinant human G-CSF (rhG-CSF, group I) or ciprofloxacin and amphotericin B (CAB, group II) for prevention of febrile leucopenia (FL)." | 9.09 | Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B. ( de Vries, EG; Hospers, GA; Mulder, NH; Schröder, CP; Sleijfer, DT; van der Graaf, WT; Willemse, PH, 1999) |
| "An experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats was used to study the impact of the duration of infection on the bactericidal activity of ceftazidime, gentamicin and ciprofloxacin." | 7.68 | Impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, MF; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1991) |
| "The antibacterial activities of ciprofloxacin and ceftazidime against Klebsiella pneumoniae in vitro and in vivo were compared." | 7.67 | Comparative activities of ciprofloxacin and ceftazidime against Klebsiella pneumoniae in vitro and in experimental pneumonia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, MF; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1987) |
| " Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0." | 5.35 | Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009) |
| "The impact of the dosage schedule on the therapeutic efficacy of antibiotics was investigated in experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats." | 5.28 | Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, BM; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1989) |
| "In a prospective randomized trial, 40 stage IV breast cancer patients undergoing intermediate high-dose chemotherapy (cyclophosphamide, 5-fluorouracil plus epirubicin or methotrexate), received either recombinant human G-CSF (rhG-CSF, group I) or ciprofloxacin and amphotericin B (CAB, group II) for prevention of febrile leucopenia (FL)." | 5.09 | Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B. ( de Vries, EG; Hospers, GA; Mulder, NH; Schröder, CP; Sleijfer, DT; van der Graaf, WT; Willemse, PH, 1999) |
| "We evaluated the virulence of Pseudomonas aeruginosa carrying bla(IMP), a metallo-beta-lactamase gene, and the efficacy of ceftazidime, imipenem-cilastatin, and ciprofloxacin in the endogenous bacteremia model." | 3.72 | Virulence of metallo-beta-lactamase-producing Pseudomonas aeruginosa in vitro and in vivo. ( Aoki, S; Gotoh, N; Hirakata, Y; Kamihira, S; Kohno, S; Kondoh, A; Miyazaki, Y; Tomono, K; Yamada, Y; Yanagihara, K, 2004) |
| "An experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats was used to study the impact of the duration of infection on the bactericidal activity of ceftazidime, gentamicin and ciprofloxacin." | 3.68 | Impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, MF; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1991) |
| "The antibacterial activities of ciprofloxacin and ceftazidime against Klebsiella pneumoniae in vitro and in vivo were compared." | 3.67 | Comparative activities of ciprofloxacin and ceftazidime against Klebsiella pneumoniae in vitro and in experimental pneumonia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, MF; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1987) |
| "Ciprofloxacin (CIP) is an antibiotic commonly used in human and veterinary medicine." | 1.91 | Experimentally exposed toxic effects of long-term exposure to environmentally relevant concentrations of CIP in males and females of the silver catfish Rhamdia quelen. ( Braga, TT; Carvalho, LÂSJ; Cestari, MM; Evans, AA; Moreira Brito, JC; Oliveira Guaita, G; Oya-Silva, LF; Perussolo, MC; Prodocimo, MM; Silva de Assis, HC, 2023) |
| " Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0." | 1.35 | Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009) |
| "The impact of the dosage schedule on the therapeutic efficacy of antibiotics was investigated in experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats." | 1.28 | Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, BM; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Carvalho, LÂSJ | 1 |
| Oya-Silva, LF | 1 |
| Perussolo, MC | 1 |
| Oliveira Guaita, G | 1 |
| Moreira Brito, JC | 1 |
| Evans, AA | 1 |
| Prodocimo, MM | 1 |
| Cestari, MM | 1 |
| Braga, TT | 1 |
| Silva de Assis, HC | 1 |
| Upadya, GM | 1 |
| Ruxana, K | 1 |
| Aoki, S | 1 |
| Hirakata, Y | 1 |
| Kondoh, A | 1 |
| Gotoh, N | 1 |
| Yanagihara, K | 1 |
| Miyazaki, Y | 1 |
| Tomono, K | 1 |
| Yamada, Y | 1 |
| Kohno, S | 1 |
| Kamihira, S | 1 |
| Maiche, AG | 1 |
| Muhonen, T | 1 |
| Shapiro, MA | 1 |
| Dever, JA | 1 |
| Sesnie, JC | 1 |
| VanderRoest, SR | 1 |
| Schröder, CP | 1 |
| de Vries, EG | 1 |
| Mulder, NH | 1 |
| Willemse, PH | 1 |
| Sleijfer, DT | 1 |
| Hospers, GA | 1 |
| van der Graaf, WT | 1 |
| Shalit, I | 1 |
| Kletter, Y | 1 |
| Halperin, D | 1 |
| Waldman, D | 1 |
| Vasserman, E | 1 |
| Nagler, A | 1 |
| Fabian, I | 1 |
| Azoulay-Dupuis, E | 1 |
| Vallee, E | 1 |
| Veber, B | 1 |
| Bedos, JP | 1 |
| Bauchet, J | 1 |
| Pocidalo, JJ | 1 |
| Roosendaal, R | 3 |
| Bakker-Woudenberg, IA | 3 |
| van den Berghe-van Raffe, M | 3 |
| Vink-van den Berg, JC | 3 |
| Michel, MF | 2 |
| Choo, PW | 1 |
| Gantz, NM | 1 |
| Michel, BM | 1 |
2 trials available for ciprofloxacin and Leukopenia
| Article | Year |
|---|---|
Granulocyte colony-stimulating factor (G-CSF) with or without a quinolone in the prevention of infection in cancer patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Ciprofloxacin; Female; Granulocyte | 1993 |
Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B.
Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxac | 1999 |
10 other studies available for ciprofloxacin and Leukopenia
| Article | Year |
|---|---|
Experimentally exposed toxic effects of long-term exposure to environmentally relevant concentrations of CIP in males and females of the silver catfish Rhamdia quelen.
Topics: Acetylcholinesterase; Animals; Biomarkers; Catfishes; Ciprofloxacin; Female; Humans; Leukopenia; Liv | 2023 |
Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin.
Topics: Administration, Oral; Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Ciproflo | 2009 |
Virulence of metallo-beta-lactamase-producing Pseudomonas aeruginosa in vitro and in vivo.
Topics: Animals; Bacteremia; beta-Lactamases; Ceftazidime; Cephalosporins; Cilastatin; Ciprofloxacin; Drug T | 2004 |
Comparative therapeutic efficacy of clinafloxacin in leucopenic mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Leukopenia; Methicillin Res | 1997 |
Immunomodulatory effects of moxifloxacin in comparison to ciprofloxacin and G-CSF in a murine model of cyclophosphamide-induced leukopenia.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Bone and Bones; Bone Marrow Cells; Cell Count; Ciprof | 2001 |
In vivo efficacy of a new fluoroquinolone, sparfloxacin, against penicillin-susceptible and -resistant and multiresistant strains of Streptococcus pneumoniae in a mouse model of pneumonia.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Female; Fluoroquinolones; Leu | 1992 |
Impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats.
Topics: Animals; Bacteremia; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Administration Schedul | 1991 |
Reversible leukopenia related to ciprofloxacin therapy.
Topics: Ciprofloxacin; Endocarditis, Bacterial; Female; Heart Valve Prosthesis; Humans; Leukopenia; Middle A | 1990 |
Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Drug Administration Schedule; Female; Ge | 1989 |
Comparative activities of ciprofloxacin and ceftazidime against Klebsiella pneumoniae in vitro and in experimental pneumonia in leukopenic rats.
Topics: Animals; Ceftazidime; Ciprofloxacin; Drug Administration Schedule; Female; Klebsiella Infections; Kl | 1987 |